Clinical trials: Neonatal Death
Pregnancy Complications, Maternal Death
Nutrition Optimalization Among Pregnant Women to Improve Maternal and Neonatal Outcome in DKI Jakarta
The goal of this MONAS Study is to learn about comprehensive monitoring and nutritional intervention among pregnant women in order to improve maternal and neonatal outcomes. The main questions it aims to answer are: 1.
- Conditions
- Pregnancy Complications, Maternal Death, Preeclampsia, Intrauterine Infection
- Trial name
- MONAS (NCT06268509)
- Testing
- Nutritional panel laboratory examination, Pregnancy supplements (other than provided by Ministry of Health), Fetomaternal ultrasound
- Where
- Indonesia
- Volunteers
- 245 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Mucopolysaccharidosis II
Long-term Follow-Up for RGX-121
RGX-121-5101 is an observational long-term follow-up study to the RGX-121-101 or RGX-121-1102 studies where participants received RGX-121, a gene therapy intended to deliver a functional copy of the iduronate-2-sulfatase gene…
- Trial name
- NCT04597385
- Testing
- Long-term Follow-Up
- Where
- 4 sites in United States, Brazil
- Volunteers
- 27 people
- Sponsor
- REGENXBIO Inc.
Arrhythmias, Cardiac, Children, Only
Mobile Electrocardiogram Monitoring for Detecting Arrhythmias in Children
The objective of this project is to evaluate the capability of a specific mobile electrocardiogram monitoring of detecting arrhythmic events in children with history of palpitation and or syncope.
- Conditions
- Arrhythmias, Cardiac, Children, Only, Congenital Heart Disease, Sudden Cardiac Death
- Trial name
- NCT05140343
- Testing
- KARDIA Mobile ECG Monitoring (KMCM)
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Centro Medico Teknon
Neonatal Death, Perinatal Death
Leveraging Interactive Text Messaging to Monitor and Support Maternal Health in Kenya
Mobile health (mHealth) interventions such as interactive short message service (SMS) text messaging with healthcare workers (HCWs) have been proposed as efficient, accessible additions to traditional health care in…
- Conditions
- Neonatal Death, Perinatal Death, Depression
- Trial name
- AI-NEO (NCT05369806)
- Testing
- Interactive two-way SMS dialogue
- Where
- 2 sites in Kenya
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Neonatal Death, Prematurity
Outcomes Following Early Parenteral Nutrition Use in Preterm Neonates
BACKGROUND An essential part of neonatal care is providing nutrition to ensure that babies grow and develop. Providing this can be difficult in premature babies because their intestines are underdeveloped.
- Trial name
- NCT03767634
- Testing
- Parenteral nutrition
- Where
- United Kingdom
- Volunteers
- 97,507 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Cardiomyopathy (Ischemic or Non-Ischemic)
Data Analysis and Evaluation of the Incidence of Life-threatening Ventricular Arrhythmias in Patients with Newly Diagnosed Cardiomyopathies of NICM or MI/CAD Origin PROTECTED from SCD by a WCD
SCD-PROTECT is an epidemiological, observational, multicenter study to assess the incidence of sudden cardiac arrest/death (SCA/SCD) in patients with newly diagnosed non-ischemic cardiomyopathy or with myocardial…
- Trial name
- SCD-PROTECT (NCT06883383)
- Where
- Germany
- Volunteers
- 19,598 people
- Sponsor
- Hannover Medical School
Neonatal Herpes Simplex Infection, Neonatal HSV Infection
Host RNA Expression Profiles and Protein Biomarkers in Neonatal Herpes Simplex Virus Infection
This study seeks to identify and test host RNA expression profiles in context to protein biomarkers in dried blood spot samples as novel diagnostic markers of neonatal herpes simplex virus infection and to improve the…
- Conditions
- Neonatal Herpes Simplex Infection, Neonatal HSV Infection, Neonatal Infection, Newborn; Infection
- Trial name
- NCT05226949
- Where
- 2 sites in Denmark
- Volunteers
- 159 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Death, Sudden, Cardiac, Ventricular Fibrillation
PREVENTION-ACHD Risk Score
Sudden cardiac death (SCD) is one of the major causes of mortality in adults with congenital heart disease (ACHD). Risk stratification for sudden cardiac death in this patient group is challenging and at the current moment there…
- Conditions
- Death, Sudden, Cardiac, Ventricular Fibrillation, Ventricular Tachycardia, Congenital Heart Disease
- Trial name
- PREVENTIONACHD (NCT03957824)
- Testing
- PREVENTION-ACHD risk score
- Volunteers
- 783 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Mortality Through Six Months of Age, Vitamin A Deficiency
Community Trial of Newborn Vitamin A Supplementation to Reduce Infant Mortality in Rural Bangladesh
The purpose of this trial is determine whether a 50,000 IU oral dose of vitamin A delivered to newborn infants within the first days of life, reduces six-month infant mortality by at least 15%.
- Trial name
- NCT00128557
- Testing
- vitamin A supplementation (15,000 ug retinol equivalents or 50,000 IU)
- Where
- Bangladesh
- Volunteers
- 15,937 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Neonatal Respiratory Distress Related Conditions, Meconium
Amnioinfusion's Protective Effects on Respiratory and Longitudinal Pediatric Outcomes After Intrapartum Meconium Exposure
Meconium in the amniotic fluid occurs in about one out of seven pregnancies and increases the chance that a newborn may have breathing problems after birth.
- Conditions
- Neonatal Respiratory Distress Related Conditions, Meconium, Perinatal Morbidity, Neonatal Acidosis
- Trial name
- PEARL (NCT07274527)
- Testing
- Intrauterine pressure catheter, Standard obstetric care at discretion of delivery provider
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Medical College of Wisconsin
Respiratory Distress Syndrome (Neonatal), Intubation Complication
InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS
The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAero™, a novel oral airway delivery device specifically designed to give Infasurf in a less complicated…
- Conditions
- Respiratory Distress Syndrome (Neonatal), Intubation Complication, Death; Neonatal
- Trial name
- Aero-05 (NCT05960929)
- Testing
- Infasurf Aero™
- Where
- 10 sites in United States
- Volunteers
- 220 people
- Sponsor
- ONY
Primary Immunodeficiency, PID
Bilateral Orthotopic Lung Transplant - Bone Marrow Transplant
The purpose of this study is to determine whether bilateral orthotopic lung transplantation (BOLT) followed by cadaveric partially-matched CD3+/CD19+ depleted bone marrow transplant (BMT) is safe and effective for individuals…
- Trial name
- BOLT-BMT (NCT03330795)
- Testing
- CD3/CD19 neg allogeneic BMT
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Fetal Death, Fetal Anomaly
Antenatal Palliative Care
In France, according to current legislation, termination of pregnancy could be performed without any upper gestational age limit, if there is a strong probability that the fetus will be affected by a particularly severe and…
- Trial name
- SPAN (NCT03795857)
- Testing
- Semi-structured interviews
- Where
- 3 sites in France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Perinatal Morbidity, Morbidity;Perinatal
Multicentric Retrospective Study of Perinatal Mortality
Background: Perinatal mortality ranges mortality from 22 gestational weeks up to the first 7 days of life and extended mortality goes up to 28 days of life.
- Conditions
- Perinatal Morbidity, Morbidity;Perinatal, Stillbirth, ICD
- Trial name
- PM-PHD-NTM (NCT05491772)
- Where
- Spain
- Volunteers
- 468 people
- Sponsor
- Corporacion Parc Tauli
Maternal and Perinatal Death Surveillance and Response (MPDSR) Implementation, Maternal Mortality
Accelerating Maternal and Newborn Survival: The AMANI Study
The goal of this cluster randomized controlled trial is to learn if a practice facilitation package (including both audit and feedback and enhanced mentorship) can increase the use of maternal and perinatal death surveillance and…
- Conditions
- Maternal and Perinatal Death Surveillance and Response (MPDSR) Implementation, Maternal Mortality, Neonatal Mortality, Perinatal Mortality
- Trial name
- AMANI (NCT07560839)
- Testing
- Audit and Feedback, Enhanced Mentorship
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sickle Cell Disease and Pregnancy
Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana
The goal of this observational study is to determine the feasibility and effectiveness of initiating a multidisciplinary sickle cell disease (SCD) obstetrics program for women with SCD in a non-academic hospital.
- Trial name
- SCOB III (NCT07488091)
- Testing
- Multidisciplinary sickle cell disease (SCD) obstetrics program for women with SCD in a non-academic hospital.
- Where
- Ghana
- Volunteers
- 198 people
- Sponsor
- University of Ghana Medical School
Fabry Disease
Arrhythmia Burden, Risk of Sudden Cardiac Death and Stroke in Patients With Fabry Disease
Fabry disease (FD) is a genetic disorder that leads to progressive accumulation of fat or 'sphingolipid' within the tissues, including the heart muscle and conductive tissue.
- Trial name
- RaILRoAD (NCT03305250)
- Testing
- Implantable Loop Recorder
- Where
- 7 sites in Australia, United Kingdom
- Volunteers
- 169 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Maternal Death, Newborn Death
Impact of the Safe Childbirth Checklist in Luapula Province of Zambia Province of Zambia
This study would like to determine if the introduction of the Safe Childbirth Checklist and associated mentorship can improve the adherence of skilled birth attendants (SBAs) to the essential practices of childbirth delivery.
- Trial name
- NCT03263182
- Testing
- Introduction of the Safe Childbirth Checklist
- Where
- 4 sites in Zambia
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Clinton Health Access Initiative Inc.
Myotonic Dystrophy, Sudden Cardiac Death
RAMYD Study - Evaluation of Arrhythmic Risk in Myotonic Dystrophy
This is a prospective multicentric Italian study to evaluate the arrhythmic risk in myotonic dystrophy type 1.
- Trial name
- NCT00127582
- Testing
- Electrophysiological study, pacemaker , implantable cardiac defibrillator or loop-recorder implant
- Where
- Italy
- Volunteers
- 537 people
- Sponsor
- Catholic University of the Sacred Heart
HIV, Cancer
Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer
Background: There are very few documents to help young adults living with advanced cancer discuss their concerns and end-of-life preferences.
- Conditions
- HIV, Cancer, Chronic Granulomatous Disease, Dock 8 Deficiency
- Trial name
- NCT02108028
- Where
- 9 sites in United States
- Volunteers
- 272 people
- Sponsor
- National Cancer Institute (NCI)