Clinical trials: Negative Thoughts
Depressive Disorder, Major
Neuroimaging Study for Decoding Emotional States and Identifying Neural Circuits to Disengage From Negative Thinking
The purpose of this study is to decode different thinking states from the brain activation patterns and identify the neural circuits that disengage from these thinking patterns using functional magnetic resonance imaging (fMRI)…
- Trial name
- RNT-decoding (NCT06254144)
- Testing
- functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Personality Disorders
The Effectiveness of a Creative Arts en Psychomotor Therapy Intervention for People With Personality Disorders. From Negative Thinking to Positive Acting.
Mental health consists of the absence of mental disorders and the presence of mental well-being. However; mental health care currently focuses mainly on mental disorders and less on promoting mental well-being.
- Trial name
- NDPD (NCT06219122)
- Testing
- Creative arts and psychomotor therapies intervention for people with personality disorders
- Where
- Netherlands
- Volunteers
- 37 people
- Sponsor
- Suzanne Haeyen
Unspecified Symptoms and Signs Involving Cognitive Functions Following Unspecified Cerebrovascular Disease, Heroin Addicts
Effect of Exercise on Cognitive Function and Mental Health in Heroin Addicts
The goal of this [type of study: exercise intervention study] is to test in describe participant health conditions. The main questions it aims to answer are: [Whether physical exercise improves executive function of male heroin…
- Conditions
- Unspecified Symptoms and Signs Involving Cognitive Functions Following Unspecified Cerebrovascular Disease, Heroin Addicts, Executive Function, Negative Thinking/Affect
- Trial name
- NCT05650983
- Testing
- Aerobic exercise; Resistance exercise
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Guangzhou Sport University
Stress, Stress Disorders
Manage Your Workingnegative Thoughts Through Hypnosis
Medical doctor generally are exposed to several risks and pressures, it is not a case that several meta-analyses have shown high stress and anxiety level in these workers. Stress management represents a very important topic.
- Trial name
- Hypnosis (NCT06778109)
- Testing
- Experimental: Hypnosis and negative memory
- Where
- 2 sites in Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Padova
Social Anxiety Disorder
Effect of Nursing Interventions Using Roy Adaptation Model with Virtual Reality on Social Anxiety in Youth
The study was conducted to determine the effect of nursing practices based on the RAM integrated with VR on the social anxiety level of young people.The main questions it aims to answer are: H1: "Nursing practices based on the…
- Trial name
- NCT06586944
- Testing
- Nursing Practices Based On Roy Adaptation Model Integrated With Virtual Reality, Roy Adaptation Model
- Where
- Turkey (Türkiye)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Aytuğ Türk
Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
Food for Thought - A Nutrition Intervention for Women Undergoing Active Treatment for Triple Negative Breast Cancer
The goal of this randomized clinical trial is to learn if a healthy eating pattern called the MIND eating plan can reduce cancer-related cognitive impairment (commonly called "chemobrain") and other symptoms commonly experienced…
- Conditions
- Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Triple-Negative Breast Carcinoma
- Trial name
- MIND-TNBC (NCT06582615)
- Testing
- Biospecimen Collection, Cognitive Assessment, Dietary Intervention
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Repetitive Negative Thinking, Healthy Controls Group - Age and Sex-matched
Emotion Regulation in RNT
The goal of this study is to understand why some people become stuck in repetitive negative thinking, which is common among individuals with depression and anxiety.
- Trial name
- NCT07513766
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Negative Thoughts, Mild Depression
How Body Awareness Promotes Mental Health During Yoga and Physical Exercise
The integrity of interoceptive networks is linked to resilience against depressive symptoms, whereas degradation of these networks is linked to apathy and deficits in emotion processing.
- Conditions
- Negative Thoughts, Mild Depression, Stress
- Trial name
- NCT03553745
- Testing
- Gentle Yoga Intervention, Rigorous Yoga Intervention, Physical Exercise Intervention
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Depressive Symptoms, Anxiety
Strategies for Coping With Negative Thoughts
The primary objective of this study is to assess the impact of two strategies for coping with negative automatic thoughts (positive thinking and cognitive restructuring) on one's belief in negative thoughts and one's affect.
- Conditions
- Depressive Symptoms, Anxiety, Negative Thinking
- Trial name
- NCT05566691
- Testing
- Positive thinking, Positive thinking + Mood induction, Thought reevaluation
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Eating Disorder Symptom, Emotional Maladjustment
Testing if Reductions in Negative Affect Yield Decreased Emotional Eating Symptoms
The purpose of this study to test a computerized treatment designed to help people with high levels of emotional eating, which is when people eat to cope with negative emotions and/or stressful situations.
- Conditions
- Eating Disorder Symptom, Emotional Maladjustment, Negative Thoughts
- Trial name
- NCT03040076
- Testing
- Cognitive Bias Treatment, Relaxation Condition
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Florida State University
Schizophrenia
A Study of RO4917838 in Combination With Antipsychotic Treatment in Patients With Schizophrenia.
This study will determine the efficacy and safety of RO4917838 in patients with schizophrenia who are stable on current antipsychotic treatment (olanzapine, que tiapine, risperidone, paliperidone or aripiprazole) with prominent…
- Trial name
- NCT00616798
- Testing
- RO4917838, Standard antipsychotic therapy
- Where
- 73 sites in United States, Austria and 8 more
- Volunteers
- 323 people
- Sponsor
- Hoffmann-La Roche
Diabetes Mellitus, Type 2
Perceived Stress and Negative Thoughts With Biomarkers in People With Type 2 Diabetes Mellitus and Healthy Subjects
The purpose of this study is to determine the effect of measured and induced negative feelings on glucose, tumor necrosis factor alpha, and cortisol levels in healthy participants and participants with type 2 diabetes mellitus.
- Trial name
- NCT04387045
- Testing
- Guilty feelings
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Francisco Carlos López Marquez
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts
The investigators are conducting this study to learn more about the cognitive and attentional processes among individuals with three types of repetitive negative thinking (RNT): mental rituals (as seen in obsessive compulsive…
- Conditions
- Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
- Trial name
- NCT04225624
- Testing
- Emotion Regulation Therapy - Attention Regulation (AR-ERT), Supportive Psychotherapy (SPT)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Massachusetts General Hospital
Depression, Anxiety
Group-Based Acceptance and Commitment Therapy Versus Active Control in University Students With Emotional Symptoms
This study evaluates the efficacy of a group-based Acceptance and Commitment Therapy (ACT) protocol compared to a non-directive group therapy used as an active control condition in university students presenting moderate to…
- Trial name
- ACT-EMA-RCT (NCT07506148)
- Testing
- Acceptance and Commitment Therapy (ACT), Non-Directive Group Therapy (NDT)
- Where
- Uruguay
- Volunteers
- 48 people
- Sponsor
- Mónica Larrosa Signorelli
Depressive Disorder, Major
Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression
In this project, the investigators use real-time fMRI neurofeedback (rtfMRI-nf) to causally relate dysfunction of right anterior insula (rAI) and right superior temporal sulcus (rSTS) connectivity with the intensity of repetitive…
- Trial name
- CNF-RNT (NCT06219681)
- Testing
- Active neurofeedback
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Chronic Pain
Repetitive Thinking in FibroMyalgia and Attentional Bias
Theoretical models of chronic pain hypothesize a privileged treatment of pain-related information that would be the basis of avoidance behaviors in chronic pain.
- Trial name
- PRFM-BA (NCT03466892)
- Testing
- Questionnaires and computer paradigm
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Rumination, Worry
Evaluating the Effects of a Self-help Mobile Phone Application on Worry and Overthinking in Young Adults Aged Between 16 and 24.
This project seeks to understand if a new self-help mobile phone application (called MyMoodCoach) is effective at reducing worry and overthinking, prominent risk factors that predict reduced well-being and poor mental health.
- Conditions
- Rumination, Worry, Repetitive Negative Thinking
- Trial name
- NCT04950257
- Testing
- digital CBT self-help including specific intervention elements to target worry and rumination.
- Where
- United Kingdom
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Body Dissatisfaction
Singing Your Negative Body-Related Thoughts
Study Objectives: 1. Examine whether singing can be used as a cognitive defusion strategy to change one's appraisals of body-related thoughts so they are less threatening to the individual. 2.
- Trial name
- NCT03646305
- Testing
- Cognitive Defusion
- Where
- Canada
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- York University
Repetitive Negative Thinking, General Anxiety Disorder
Training Protocol 'Drop it'. The Impact of a Training Protocol Focused on Coping With Negative Repetitive Thinking on Cognitive and Behavioural Functioning of People Suffering From GAD or Minor or Moderate Depressive Disorder or Depressive Disorder in Remission
Repetitive negative thinking (RNT) plays an important role in different psychiatric disorders, such as depressive and anxiety disorders, complicated grief, posttraumatic stress disorders, anorexia nervosa.
- Conditions
- Repetitive Negative Thinking, General Anxiety Disorder, Depressive Disorder, Depression
- Trial name
- Drop It (NCT01983033)
- Testing
- Drop It training session, treatment as usual
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
Intrusive Negative Thinking
Intervention for Intrusive Negative Thinking
Intrusive negative thinking styles such as rumination are typical of many psychiatric disorders, are difficult to treat, and predict poor treatment outcome.
- Trial name
- NCT02394704
- Testing
- Sensory attention training
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- University of Pittsburgh