Clinical trials: Neck Scar
Scar Conditions and Fibrosis of Skin
Dermabrasion for Free Flap Aesthetic Enhancement
The purpose of this study is to evaluate the aesthetic benefit and safety of serial dermabrasion for free flap skin paddles and donor site scars in head and neck reconstruction.
- Trial name
- NCT07233200
- Testing
- Dermabrasion
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Postoperative Surgical Scar, Scar
Effect of an Intraoperative Polynucleotide Injection on Scar Quality After Thyroidectomy
The goal of this clinical trial is to learn whether a single polynucleotide injection can improve scar quality after thyroid or parathyroid surgery in adults. It will also assess the safety of the injection.
- Conditions
- Postoperative Surgical Scar, Scar, Scar Formation, Neck Scar
- Trial name
- NCT07791953
- Testing
- Polynucleotide (PN-HPT), Sterile 0.9% Sodium Chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Acne Scars, Wrinkles
Collagen Injections for the Treatment of Acne Scars and Wrinkles
The purpose of this study is to find out if autologous (your own) fibroblast injections are effective for the treatment of acne scars and wrinkles.
- Trial name
- NCT01704209
- Testing
- Fibroblast Treatment, Vehicle
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Scar Niche, Abnormal Uterine Bleeding
Sublingual Misoprostol Versus No Cervical Priming Before Hysteroscopic Resection of Symptomatic Uterine Niches
The purpose of the study is to evaluated whether preoperative sublingual misoprostol can enhance the effectiveness and safety of niche resection in patients with symptomatic uterine niche.
- Conditions
- Scar Niche, Abnormal Uterine Bleeding, Cesarean Section Complications
- Trial name
- NCT07271056
- Testing
- Misoprostol 200mcg Tab, Hysteroscopic resection of uterine niche, Saline-infusion Sonohysterography
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Benha University
Cicatrix, Lipodystrophy
Evaluating Performance and Safety of the Medical Device Jalucomplex in the Treatment of Facial and Neck Tissue Defects
The Research Question of the present study is the following: in a population of men and women presenting facial and neck dermal tissue defects (scars, hypertrophic scars, depressed plaques, and lipodystrophy defects) will linear…
- Conditions
- Cicatrix, Lipodystrophy, Plaque
- Trial name
- NCT05239351
- Testing
- Jalucomplex
- Where
- Romania
- Volunteers
- 48 people
- Sponsor
- I.R.A. Istituto Ricerche Applicate S.p.A.
Suture, Dermatologic Surgery
Aesthetic Outcome of Running Cuticular Suture Distance (2mm vs 5mm)
It is standard teaching that the top layer of sutures should be placed 3-5mm from the wound edge. However, there is lack of data regarding the most optimal placement of sutures from the wound edge for the best cosmetic outcome.
- Conditions
- Suture, Dermatologic Surgery, Scar, Cosmetic Outcome
- Trial name
- NCT04870008
- Testing
- Suture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Wrinkle, Pigmentation
Device for Improving Skin Quality and Texture on the Face and Neck
The goal of this clinical trial is to investigate the effect of the BTL-785F device (with BTL-785-4-4 tip on BTL-785-4 applicator) on the improvement of skin quality and texture on the face and neck in healthy adult volunteers.
- Conditions
- Wrinkle, Pigmentation, Skin Laxity, Skin Scarring
- Trial name
- NCT06645366
- Testing
- Treatment with BTL-785F
- Where
- 3 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Surgical Flaps, Skin Pigmentation
Evaluation of the Postoperative Effect of Expanded Pedicled Deltopectoral Flap to Repair the Facial-Cervical Scars
This study evaluates the effect of Expanded Pedicled Deltopectoral Flap on facial-cervical scars repair, including flap sensation, L*a*b* value,flap's elasticity,melanin content, hemoglobin content, and evaluation of scar and…
- Conditions
- Surgical Flaps, Skin Pigmentation, Sensory Defect
- Trial name
- NCT03735641
- Testing
- Expanded Pedicled Deltopectoral Flap
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Preterm Labor
The Cervical Length and Thickness of Cesarean Section Scar With Preterm Labor
Although the Cesarean section is one of the most common obstetric operations around the world, the World Health Organization recognizes that where cesarean rates are higher than 10%, there is no increase in beneficial maternal…
- Trial name
- NCT04554745
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Assiut University
Scarred Uterus
A Comparison of Balloon Catheter Versus Ocytocin for Cervical Ripening on Scarred Uterus With Unfavorable Cervix
Increasing cesarean rate in France is worrying. Different methods are described for ripening labor : the use of prostaglandins is described but maybe dangerous for patients with scarred uterus and is not recommended.
- Trial name
- NCT01711060
- Testing
- oxytocin, balloon catheter
- Where
- 7 sites in France
- Volunteers
- 204 people
- Sponsor
- Poitiers University Hospital
Breast Ptosis, Mammaplasty
Autologous Free Dermal Graft Support in Superior Pedicle Vertical Scar Reduction Mammaplasty
The goal of this observational study is to learn whether using an autologous free dermal graft during breast reduction surgery helps maintain lower breast pole shape over time in women undergoing primary bilateral reduction…
- Conditions
- Breast Ptosis, Mammaplasty, Lower Pole Elongation, Postoperative Breast Pseudoptosis
- Trial name
- NCT07657962
- Testing
- Autologous Free Dermal Graft Support
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Cumhuriyet University Hospital
Herpes Genitalis, Genital Wart
Safety and Efficacy of Laser Therapy in Gynaecology
The aim of this study is to retrospectively evaluate the effectiveness and safety of Er:YAG laser for treatment of different gynecological indication, e.g.
- Conditions
- Herpes Genitalis, Genital Wart, Lichen Sclerosus, Cervical Intraepithelial Neoplasia
- Trial name
- NCT04073082
- Where
- Slovenia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Juna d.o.o.
Termination of Pregnancy
Termination of Pregnancy in Previous Scarred Uterus: PGE1 Versus Cervical Folleys
As mentioned above, previous studies have shown variable results and the best among these two is still in debate, so there must be re-evaluation of results on this topic.
- Trial name
- NCT07604051
- Testing
- PGE1 tablet, cervical folleys
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dr Mudassar Saeed Pansota
Nevus, Cicatrix
A Trial to Investigate Scar Improvement Efficacy of RN1001 (Avotermin) After Head and Neck Naevi Excision
This trial will investigate whether four doses of RN1001 (20ng, 50ng, 100ng and 200ng) are efficacious in preventing or reducing the resultant scar, as compared to placebo, when applied intradermally to wound margins following…
- Trial name
- NCT00656227
- Testing
- Avotermin
- Where
- United Kingdom
- Volunteers
- 239 people
- Sponsor
- Renovo
Breast Hypertrophy
Vertical Scar Versus Inferior Pedicle Reduction Mammoplasty
Main research question: Is vertical scar reduction mammoplasty superior when compared to inferior pedicle reduction mammoplasty in terms of patient quality of life and cost-effectiveness? Why is this research important?: There is…
- Trial name
- NCT00149344
- Testing
- Vertical scar versus inferior pedicle reduction mammoplasty
- Where
- Canada
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cutaneous Sutures and Scar Cosmesis
Suturing Distance From the Wound Edge, 2 mm vs 5 mm
This study aims to investigate whether the spacing of the interrupted cutaneous sutures affects surgical wound cosmesis on the face and neck.
- Trial name
- NCT03330041
- Testing
- Fast absorbing gut suture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Wound Closure Techniques
Closure Techniques and Scar Appearance
The goal of this study is to assess whether wound closure with skin adhesive or running stitches combined with skin adhesive will be superior to standard wound sutures.
- Trial name
- NCT01352533
- Testing
- Running polypropylene closure, Tissue Adhesive (Derma-Bond), Subcuticular polyglactin-910 combined with tissue adhesive
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Surgical Wound
Outcomes Comparing Different Methods of Skin Closure in Patients Undergoing Head and Neck Surgery.
When patients undergo neck dissection surgeries, the current standard of care is to close the skin layer with either metal staples, which are removed a few days post-operatively, or with sutures, which can be absorbable or…
- Trial name
- NCT02936063
- Testing
- Surgical staples, Subcuticular sutures
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Scar
Explore the Short- and Mid-term Effects of Fespixon in Scar Cosmesis Following Cervical or Abdominal Surgery
The aim of this study is to evaluate the efficacy of the Fespixon cream for prevention and/or appearance reduction of different types of linear scars during the 12-week treatment phase, which is assessed by the blinded…
- Trial name
- NCT05271708
- Testing
- Fespixon cream
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- National Defense Medical Center, Taiwan
Scar
Botox in the Healing of Surgical Wounds of the Neck
The investigators hypothesize that Botox A will reduce scarring and improve healing of surgical neck wounds.
- Trial name
- NCT01177358
- Testing
- Botulinum Toxin Type A, Normal Saline
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority