Clinical trials: Nebulized Lidocaine
Stress Response
Effect of Nebulized Lignocaine on the Stress Response of Endotracheal Intubation in Pediatrics Undergoing Tonsillectomy Operation Monitored by Rise in Serum Cortisol Level Post Intubation
This randomized clinical trial aims to is examining the effect of preoperative nebulized lidocaine on the stress response to intubation, monitored by rise in serum cortisol level post intubation
- Trial name
- NCT07139730
- Testing
- Lignocaine 2% concentration solution
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemodynamic Instability
Nebulized Lidocaine, Dexmedetomedine and Their Combination in Direct Laryngoscopy Surgery
Direct laryngoscopy (DL) procedure is typically done under general anaesthesia as a day case. It is a short but irritating.Various drugs and drug combinations have been used to attenuate stress response to DL.Administrating…
- Trial name
- NCT04659057
- Testing
- Nebulized Lidocaine, Nebulized dexmedetomidine, Nebulized lidocaine and dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia of Mucous Membrane
Comparison of Topical and Nebulized Anesthesia in Patients Undergoing Esophago-Gastro-Duodenoscopy
This study compares the effect of nebulized lidocaine and lidocaine spray in patients undergoing esophago-gastro-duodenoscopy. The investigators evaluate the success rate of the procedure between two methods.
- Trial name
- NCT02317770
- Testing
- Lidocaine Spray, Nebulized Lidocaine
- Where
- Thailand
- Volunteers
- 110 people
- Sponsor
- Mahidol University
Bronchopulmonary Disease
Nebulized Lignocaine for Topical Airway Anesthesia During Flexible Bronchoscopy: A Randomized Controlled Trial
Flexible bronchoscopy is one of the most widely performed procedures for diagnosis of various bronchopulmonary diseases. Most patients tolerate the procedure well although cough is often reported as a distressing symptom.
- Trial name
- NEBULA (NCT03040193)
- Testing
- Lignocaine Nebulization, Saline Nebulization
- Where
- India
- Volunteers
- 200 people
- Sponsor
- All India Institute of Medical Sciences
Blood Pressure After Nerve Block, Hemodynamic Stability During Awake Intubation
COMPARISON OF AIRWAY NERVE BLOCK VERSUS NEBULIZED LIDOCAINE ON HEMODYNAMIC RESPONSES DURING AWAKE FIBEROPTIC INTUBATION
This prospective randomized controlled trial aims to compare the effectiveness of airway nerve blocks versus nebulized lidocaine in attenuating hemodynamic responses during awake fiberoptic intubation in adult patients with…
- Trial name
- NCT07627100
- Testing
- Nebulized Lidocaine, Nerve Block
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Mayo Hospital Lahore
Anesthesia Intubation Complication
Dexmedetomidine or Lidocaine for Lessening the Hemodynamic Responses to Laryngoscopy and Intubation
Laryngoscopy, tracheal intubation, surgical stimulation, and extubation unleash remarkable sympathetic activity and are associated with transient but significant hemodynamic changes.
- Trial name
- NCT05941767
- Testing
- Dexmedetomidine nebulization, Lidocaine nebulization, Dexmedetomidine IV
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Airway Complication of Anesthesia
Effect of Nebulized Lidocaine on the Quality of Laryngeal Mask Airway Insertion
The primary outcome of this study will be the effect of lidocaine nebulization before LMA insertion on LMA insertion score (within 1 minute of LMA insertion) in adult patients undergoing surgery under general anesthesia.
- Trial name
- NCT03361397
- Testing
- Lidocaine Hydrochloride, Distilled Water
- Volunteers
- 80 people
- Sponsor
- Assiut University
Procedural Anxiety, Procedural Pain
Nebulized Lidocaine and Intranasal Midazolam for NGT Insertion in Children
Nasogastric tube (NGT) is a commonly performed procedure in the Emergency Department. Although it is not a major procedure, it is usually associated with a bad experience and cause discomfort and pain in kids.
- Trial name
- NCT04571879
- Testing
- Nebulized Lidocaine, Intranasal Midazolam
- Where
- 2 sites in Qatar
- Volunteers
- 48 people
- Sponsor
- Hamad Medical Corporation
Sore Throat, Dexmedetomidine Analgesia
Effect of Preoprative Nebulized Dexmedetomidine Compared to Nebulized Lidocaine in Attenuating Sore Throat Following Tonsillectomy In Childern.
The aim of the study is to compare the effect of nebulized Dexmedetomidine compared to nebulized Lidocaine on postoperative sore throat in childern undergoing Tonsillectomy.
- Conditions
- Sore Throat, Dexmedetomidine Analgesia, Tonsillectomy
- Trial name
- NCT07780760
- Testing
- Group D (dexmedetomidine group), Group L (Lidocaine group)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Fayoum University Hospital
Emergence Agitation, Emergence Delirium
Effect of Nebulized Lignocaine on Emergence Agitation After Sevoflurane Anesthesia in Pediatric Patients Undergoing Tonsillectomy
Emergence agitation is a frequent recovery complication in young children following general anesthesia with sevoflurane. It is characterized by confusion, crying, disorientation, and non-purposeful thrashing during early…
- Conditions
- Emergence Agitation, Emergence Delirium, Postoperative Pain
- Trial name
- NCT07871266
- Testing
- Lidocaine, 0.9% Normal Saline
- Volunteers
- 60 people
- Sponsor
- Assiut University
Migraine Headache
A Double Blind Randomized Controlled of Placebo and Nebulized Lidocaine for Migraine Headache
Migraine headaches have previously been shown to be responsive to intranasal lidocaine in a small study. Using a nebulizer to administer the drug would improve the feasibility of using the treatment.
- Trial name
- NCT00287781
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Kern Medical Center
Dexmedetomidine, Lidocaine
A Comparative Study to Measure the Effect of Nebulized Dexmedetomidine
A comparative study to measure the effect of nebulized dexmedetomidine - lidocaine for controlling postoperative pain after tonsillectomy in adults.
- Conditions
- Dexmedetomidine, Lidocaine, Tonsillectomy
- Trial name
- NCT05158348
- Testing
- Dexmedetomidine Hydrochloride, Nebulized lidocaine, Local infiltration of lidocaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
COVID-19 Acute Respiratory Distress Syndrome
Efficacy of Nebulized Lidocaine, Salbutamol, and Beclomethasone Plus Salbutamol in the Covid-19 Patients With ARDS on Non-invasive Ventilation; Randomized Control Trial
The COVID-19, a pandemic as declare by WHO1, has a devastating impact on health and economic worldwide2. Literature suggests that acute respiratory distress syndrome (ARDS) develops over 20% of the infected individuals with…
- Trial name
- NCT04979923
- Testing
- Lidocaine
- Where
- Pakistan
- Volunteers
- 81 people
- Sponsor
- Sheikh Zayed Medical College
Postoperative Respiratory Complication
Nebulized Lidocaine vs 3% Sodium Chloride in Pediatric Adenoid/Tonsil Surgery
This prospective, randomized clinical trial aims to evaluate the effect of preoperative nebulized lidocaine and nebulized 3% hypertonic sodium chloride (NaCl) on the incidence of postoperative respiratory complications in…
- Trial name
- NCT07267897
- Testing
- Nebulize Lidocaine, Nebulize %3 Sodium Chloride
- Volunteers
- 90 people
- Sponsor
- Sakarya University
Fiberoptic Bronchoscopy (FOB), Lung Cancer (Diagnosis)
Nebulized Lidocaine And Ketamine Before Fiberoptic Bronchoscopy
The current study is looked for the comparison between nebulized lidocaine and ketamine, nebulized lidocaine, and usual lidocaine spray in the oral and nasal cavities before flexible bronchoscopy.
- Conditions
- Fiberoptic Bronchoscopy (FOB), Lung Cancer (Diagnosis), Premedication
- Trial name
- NCT07743333
- Testing
- Nebulized lidocaine and ketamine, Nebulized Lidocaine, Lidocaine spray (2%)
- Where
- Egypt
- Volunteers
- 134 people
- Sponsor
- Alexandria University
Patients With Indication for Flexible Bronchoscopy
A Randomized Trial of 4% Nebulized Lignocaine vs. 10% Lignocaine Spray in Patients Undergoing Flexible Bronchoscopy
Flexible bronchoscopy is common procedure used in the diagnosis and treatment of a variety of tracheobronchial diseases. During routine diagnostic flexible bronchoscopy, the most distressing symptom experienced by the patients is…
- Trial name
- NCT03109392
- Testing
- Nebulized Lignocaine, Lignocaine spray, Combined spray and nebulization
- Where
- India
- Volunteers
- 1,050 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Sore Throat
Comparing Efficacy Preoperative Nebulized: Ketamine , Mgspo4 ,and Lidocaine In Attenuating Endotracheal Sore Throat
One of the most common complications after endotracheal intubation is sore throat Lidocaine jelly or spray, preoperative gargles with licorice or ketamine or I.V steroids used for prophylaxis against POST are expensive ,and…
- Trial name
- NCT03729973
- Testing
- Ketamine, Magnesium Sulfate, Lidocaine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Lidocaine Spray, Nebulized Lidocaine
Comparison Between Different Ways for Using Lidocaine During FB
compare the efficacy and safety of nebulized lidocaine, oropharyngeal lidocaine spray, or their combination for better outcome of topical anesthesia in subjects undergoing diagnostic FB; severity of cough , pain during procedure…
- Conditions
- Lidocaine Spray, Nebulized Lidocaine, Lung Diseases, Lung Cancer
- Trial name
- NCT06563050
- Testing
- Nebulized lidocaine, Lidocaine spray, Combination of nebulized lidocaine and lidocaine spray
- Volunteers
- 240 people
- Sponsor
- Assiut University
Hemodynamics After Endotracheal Intubation
Preoperative Topical Lidocaine Versus Intravenous Fentanyl to Obtund the Stress of Intubation Under Anesthesia.
To compare the effectiveness of preoperative combined topical airway anesthesia consisting of nebulised, mouth rinsing and gargling with lidocaine versus intravenous fentanyl to prevent the stress of endotracheal intubation by…
- Trial name
- NCT07533643
- Testing
- topical lidocaine, Fentanyl (Low Dose)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Sore Throat
Effect of Nebulized Lidocaine on Postoperative Sore Throat
The purpose of this study is to test the hypothesis that use of preoperative nebulized lidocaine is reduced the incidence of postoperative sore throat after endotracheal intubation.
- Trial name
- NCT03779516
- Testing
- Saline, Lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Antalya Training and Research Hospital