Clinical trials: Natural Language Processing (NLP)
Thyroid Cancer, Large Language Models
Evaluation of an Artificial Intelligence-enabled Clinical Assistant to Support Thyroid Cancer Management
This study aims to evaluate the clinical feasibility of adopting artificial intelligence (AI)-based models to improve clinical management of thyroid cancer.
- Trial name
- NCT07234539
- Testing
- AI-enabled clinical assistant
- Where
- 2 sites in Hong Kong
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Neonatal Death, Perinatal Death
Leveraging Interactive Text Messaging to Monitor and Support Maternal Health in Kenya
Mobile health (mHealth) interventions such as interactive short message service (SMS) text messaging with healthcare workers (HCWs) have been proposed as efficient, accessible additions to traditional health care in…
- Conditions
- Neonatal Death, Perinatal Death, Depression
- Trial name
- AI-NEO (NCT05369806)
- Testing
- Interactive two-way SMS dialogue
- Where
- 2 sites in Kenya
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Crohn's Disease (CD)
Research on the Whole Process of AI Intelligent Management System for the Diagnosis and Treatment of Inflammatory Bowel Diseases
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is a chronic immune-mediated disorder requiring long-term management.
- Conditions
- Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Crohn's Disease (CD), Ulcerative Colitis (UC), Artificial Intelligence (AI)
- Trial name
- NCT07590271
- Where
- Taiwan
- Volunteers
- 4,500 people
- Sponsor
- Taichung Veterans General Hospital
Psychosis, Schizophrenia
CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies
The primary objective of this grant is to develop and evaluate an Artificial Intelligence-based clinical training tool--CBTpro--to support high-quality skills training in CBT for psychosis (CBTp).
- Conditions
- Psychosis, Schizophrenia, Schizo Affective Disorder, Bipolar Disorder
- Trial name
- CBTpro (NCT05127837)
- Testing
- CBTpro
- Where
- 13 sites in United States
- Volunteers
- 601 people
- Sponsor
- University of Washington
Palliative Care, Generative Artificial Intelligence
Patient Aid for Theory-Driven Health Communication (PATH): Translating Goal-Power Theory Into an Instrument and Generative AI Support for Palliative Care Communication
The goal of this clinical trial is to learn whether an artificial intelligence (AI)-supported communication tool can help improve communication between people receiving palliative care and their healthcare providers.
- Conditions
- Palliative Care, Generative Artificial Intelligence, Natural Language Processing (NLP)
- Trial name
- NCT07692711
- Testing
- NurseChat+
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Headache Disorders
NLP Headache Speech (NLPH-SPEECH): a Cross-sectional Study on Natural Language Processing Analysing Spoken Monologues by Headache Patients
The research collects spoken descriptions of headache disorders by participants with headache disorders. The speech recordings are analyzed by natural language processing (NLP) tools to analyse linguistic properties of the texts…
- Trial name
- NLPH SPEECH (NCT05204316)
- Testing
- Digital Analysis of Speech
- Where
- Belgium
- Volunteers
- 2 people
- Sponsor
- University Hospital, Ghent
Prostate Cancer
NLP-Based Feedback to Improve Risk Comms and Informed Shared Decision Making
In this pilot study, the investigators will show feasibility of the NLP-based feedback system in 20 consultations of men with newly diagnosed prostate cancer.
- Trial name
- NCT05923684
- Testing
- NLP-based Feedback
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cedars-Sinai Medical Center
Opiod Use Disorder
Chicago Data-driven Opioid Use Disorder Screening, Engagement, Treatment and Planning System
This study, called the Chicago Data-driven Opioid use disorder Screening, Engagement, Treatment and Planning (C-DOSETaP) System, tests a new system of clinical care for patients with opioid use disorder (OUD) across a large…
- Trial name
- C-DOSETaP (NCT07498322)
- Testing
- OUD screening, MOUD, Continuity of care
- Where
- United States
- Volunteers
- 271,031 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Crohn Disease, Rectal Fistula
A Study Using Artificial Intelligence to Identify Adults With Complex Perianal Fistulas Associated With Crohn's Disease
Natural Language Processing and machine learning are examples of artificial intelligence tools. This study will check if these tools correctly identify people with Crohn's disease with complex perianal fistulas from their medical…
- Trial name
- INTUITION-CPF (NCT04844593)
- Where
- 3 sites in Spain
- Volunteers
- 32 people
- Sponsor
- Takeda
Substance Use Disorder (SUD), Addiction
NLP Analysis of Weekly Narratives for Dynamic Clinical Assessment in SUD
This prospective observational study follows adults undergoing residential rehabilitation for severe substance use disorders at a specialized treatment center in Mexico.
- Conditions
- Substance Use Disorder (SUD), Addiction, Anxiety, Emotional Dysregulation
- Trial name
- DYNA-NLP (NCT07595614)
- Testing
- Residential rehabilitation as usual
- Where
- Mexico
- Volunteers
- 35 people
- Sponsor
- Lauro Gutiérrez Castro
Radiography, Oral Health
Large Language Models for Dental Radiology Report Generation From Structured Textual Data
The purpose of this observational methodological study is to evaluate whether large language models can transform structured dental radiology data into clear narrative radiology reports.
- Conditions
- Radiography, Oral Health, Large Language Model, Natural Language Processing (NLP)
- Trial name
- DENT-LLM (NCT07676318)
- Testing
- Large language model-assisted radiology report generation
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Hospital of the Ministry of Interior, Kielce, Poland
Headache Disorders, Tension-Type Headache
An Open Internet-based Survey and Natural Language Processing Project Analysing Written Monologues by Headache Patients
Headache disorders are among the most prevalent medical conditions worldwide. The diagnosis of headache disorders is based on medical history taking.
- Conditions
- Headache Disorders, Tension-Type Headache, Migraine Disorders, Cluster Headache
- Trial name
- NLPH-OPEN (NCT05153876)
- Testing
- Questionnaires
- Where
- Belgium
- Volunteers
- 1,150 people
- Sponsor
- University Hospital, Ghent
Functional Gastrointestinal Disorders
NLP to Aid in the Evaluation and Diagnosis of FGIDs
The study has two arms, where the same natural language processing (NLP) and probabilistic graphical modeling technology will be utilized on patients' report of symptoms in both arms.
- Trial name
- NCT05501028
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Massachusetts General Hospital
COVID-19
Natural Language Processing (NLP) Analysis of Free Text Notes to Investigate Coronavirus (COVID-19)
A retrospective cohort study investigating clinical notes using Natural Language Processing in combination with structured data from the Electronic Health Record (EHR) to create a database for analytics to identify features…
- Trial name
- NCT04432961
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Malignancy, Immune Related Adverse Events
Evaluating Informatics-assisted Immune-related Adverse Event Detection to Improve Registration Onto a Biorepository
Immunotherapies have improved cancer outcomes, but have a unique profile of immune-related adverse events (irAEs). Biorepositories have been established to collect data and samples to help improve our understanding of irAEs…
- Trial name
- NCT06789601
- Testing
- Informatics system for eligibility monitoring, Standard eligibility monitoring
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Brigham and Women's Hospital
Opioid Use Disorder, Opioid Misuse
Natural Language Processing for Screening Opioid Misuse
This is a clinical study to implement and evaluate a hospital-wide, operational intervention for a real-time natural language processing (NLP)-driven clinical decision support (CDS) tool, called Substance Misuse Algorithm for…
- Trial name
- NCT05745480
- Testing
- Opioid Misuse Screening with an Addiction Consult Service
- Where
- United States
- Volunteers
- 47,502 people
- Sponsor
- University of Wisconsin, Madison
Prostate Cancer, Shared Decision Making
RCT of NLP-Based Feedback for Improving SDM in Men With Localized Prostate Cancer
The purpose of the research is to assess the impact of a natural language processing + artificial intelligence (NLP+AI)-based risk communication feedback system to improve quality of risk communication of key tradeoffs during…
- Conditions
- Prostate Cancer, Shared Decision Making, Risk Communication
- Trial name
- NLP RCT (NCT06856694)
- Testing
- NLP+AI Report
- Where
- United States
- Volunteers
- 283 people
- Sponsor
- Cedars-Sinai Medical Center