Clinical trials: Myopic Astigmatism
Refractive Errors, Myopia
Safety and Suitability of ICL for Correction of Refractive Errors Without the Use of Dispersive OVDs
The goal of this observational study is to test whether surgeries for lenses designed to be implanted in the eye to correct refractive error can be done without the need for using viscoelastic substances that are used routinely…
- Conditions
- Refractive Errors, Myopia, Myopic Astigmatism, Hypermetropia
- Trial name
- NCT06371079
- Testing
- phakic intraocular lens implantation traditional, phakic intraocular lens implantation reduced OVD
- Where
- Iraq
- Volunteers
- 448 people
- Sponsor
- Loay Abdulmutalib Almusawi
Myopia, Astigmatism
Contralateral Comparison of Three Excimer Laser Systems in Performing LASIK
The purpose of this study is to compare LASIK outcomes using the WaveLight ALLEGRETTO WAVE™ wavefront guided or optimized excimer laser treatment with the AMO/VISX CustomVue™ and the LADARVision 4000 excimer laser treatment.
- Trial name
- WLCVLV-001 (NCT00821236)
- Testing
- Excimer Laser, AMO/VISX CustomVue™, LADARVision 4000 excimer laser
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Durrie Vision
Myopia, Hyperopia
Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
A new multi-purpose solution (MPS)was clinically evaluated against Opti-Free RepleniSH MPS at specific time points over the course of four days. The study was conducted with PureVision lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01024855
- Testing
- RevitaLens OcuTec MPS (Investigational MPS) and Opti-Free RepleniSH MPS (control)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Myopia, Astigmatism
Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems
The purpose of this study is to evaluate the lipid uptake, wetting characteristics, and visual performance of AIR OPTIX® AQUA and ACUVUE® OASYS® with HYDRACLEAR® contact lenses when used in conjunction with two contact lens care…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01699750
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE® PUREMOIST® MPDS
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Comparison of Topography Guided LASIK With WaveLight® EX500 to SMILE With Zeiss VisuMax
The purpose of this study is to compare Topography Guided Laser In Situ Keratomileusis (LASIK) corneal surgery to Small Incision Lenticule Extraction (SMILE) corneal surgery for the treatment of myopia with astigmatism.
- Trial name
- NCT02987660
- Testing
- Topography Guided LASIK, Small Incision Lenticular Extraction, WaveLight EX500 Excimer Laser System
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Alcon, a Novartis Company
Myopia, Astigmatism
Product Performance of a Toric Contact Lens
Product performance of a Bausch \& Lomb Toric Contact Lens compared to Ciba Vision Focus Daily Toric Contact Lens
- Trial name
- NCT00658996
- Testing
- SofLens DD Toric, Ciba Vision Focus Dailies Toric Contact Lens
- Where
- Malaysia
- Volunteers
- 220 people
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism, Myopia
Comparative Clinical Evaluation of Soft Toric Lens Designs
This study is evaluating the initial fit of toric contact lenses.
- Trial name
- NCT01552876
- Testing
- etafilcon A, nelfilcon A, Filcon II 3
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism, Myopia
Evaluation of Two Daily Disposable Contact Lenses for Wearers With Astigmatism
The purpose of this trial is to compare the performance of two contact lenses for contact lens wearers with astigmatism.
- Trial name
- NCT01207466
- Testing
- Nelfilcon A investigational contact lens, Nelfilcon A commercial contact lens
- Volunteers
- 95 people
- Sponsor
- CIBA VISION
Myopia, Astigmatism
Multicenter Dispensing Study of Biofinity Toric Made-To-Order Lenses in Extended Power Ranges
The study hypothesis is that the Biofinity Toric XR lenses will perform as well as or better than the participants' habitual contact lenses.
- Trial name
- NCT02193178
- Testing
- comfilcon A Toric
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- CooperVision, Inc.
Refractive Error
WaveLight® Refractive Myopic Study
The purpose of this study is to evaluate outcomes of subjects undergoing myopic surgery using the WaveLight® Refractive Suite (Excimer EX500 and Femtosecond FS200 lasers).
- Trial name
- NCT01941498
- Testing
- Wavelight® Refractive Suite, LASIK surgery
- Volunteers
- 104 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Clinical Comparison of Two Daily Disposable Toric Lenses
The purpose of this trial was to compare the performance of two contact lenses commercially available for people with astigmatism.
- Trial name
- NCT01362894
- Testing
- nelfilcon A contact lens, etafilcon A contact lens
- Volunteers
- 240 people
- Sponsor
- CIBA VISION
Myopia, Astigmatism
Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Soft Contact Lens Wearers
The purpose of this study is demonstrate substantial equivalence of an investigational contact lens disinfecting solution to a commercially available contact lens solution in silicone hydrogel and soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Hyperopia, Refractive Error
- Trial name
- NCT01912768
- Testing
- FID 120947A contact lens disinfecting solution, renu fresh multi-purpose solution, Soft contact lenses
- Volunteers
- 362 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Prospective Study of an Investigational Toric Soft Contact Lens
The purpose of this study was to demonstrate substantial equivalence of an investigational toric soft contact lens to the commercially available Focus® DAILIES® Toric soft contact lens when worn in a daily wear, daily disposable…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01461811
- Testing
- Nelfilcon A toric contact lenses (with comfort additives), Nelfilcon A toric contact lenses
- Volunteers
- 154 people
- Sponsor
- CIBA VISION
Myopia, Astigmatism
Technolas 217z Laser With Zyoptix Aspheric Algorithm Used for the LASIK Treatment of Myopia and Myopic Astigmatism.
The purpose of this study is to evaluate the safety and effectiveness of the Bausch \& Lomb Technolas 217z laser with the investigational Zyoptix Aspheric Algorithm when used for LASIK treatment of myopia and myopic astigmatism.
- Trial name
- NCT00769808
- Testing
- Bausch & Lomb 217z Excimer Laser
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error, Myopia
Comparative Evaluation of Contact Lens Centering of DAILIES® AquaComfort Plus® Versus 1-DAY ACUVUE® MOIST® in Japan
The purpose of this study is to evaluate lens centration and subjective impressions of DAILIES® AquaComfort Plus® (DACP) lenses compared to 1-DAY ACUVUE® MOIST® (1DAM) lenses in ball sports players.
- Conditions
- Refractive Error, Myopia, Myopic Astigmatism
- Trial name
- NCT02103309
- Testing
- Nelfilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 42 people
- Sponsor
- Alcon Research
Refractive Error
WaveLight® Refractive Flap Accuracy Study
The purpose of this study is to evaluate the accuracy of the WaveLight FS200 femtosecond laser, as assessed by 1 day and 1 month post-operative optical coherence tomography (OCT) anterior segment corneal measurements compared to…
- Trial name
- NCT01941485
- Testing
- WaveLight® Refractive Suite, LASIK surgery
- Volunteers
- 60 people
- Sponsor
- Alcon Research
Astigmatism, Ametropia
Clinical Comparison of Two Daily Disposable Toric Soft Contact Lenses
The primary purpose of this study is to demonstrate noninferiority in the visual acuity at distance when wearing PRECISION1™ for Astigmatism (P1fA) soft contact lenses compared to another commercially available, soft toric…
- Conditions
- Astigmatism, Ametropia, Myopia
- Trial name
- NCT05483127
- Testing
- Verofilcon A toric soft contact lenses, Stenfilcon A toric soft contact lenses
- Where
- 11 sites in United States
- Volunteers
- 153 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
1-Week Dispensing Evaluation of Kalifilcon A Toric Contact Lenses Compared to Ultra for Astigmatism
This single-site, randomized, double-masked (participant and investigator), 2-way crossover, repeated-measures dispensing study evaluated the visual performance of kalifilcon A daily disposable toric (LD213001) contact lenses…
- Trial name
- NCT05320042
- Testing
- kalifilcon A daily disposable toric contact lenses, Ultra for Astigmatism (samfilcon A) contact lenses
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Stable Myopic Refractive Error, With or Without Astigmatism
Prospective S&E Study of Wavefront-guided PRK for Myopia With iDesign Advanced Wavescan Studio™ System and Star S4 IR™
Prospective, multicenter, bilaterally-treated, open-label, non-randomized clinical trial.
- Trial name
- NCT02675751
- Testing
- STAR S4 IR laser with iDesign
- Volunteers
- 167 people
- Sponsor
- Abbott Medical Optics
Refractive Error, Astigmatism
Visual Performance Investigation of Two Toric Soft Contact Lenses
The purpose of this study is to compare the amount of coma as measured by aberrometry induced by two silicone hydrogel toric lenses in astigmatic participants.
- Conditions
- Refractive Error, Astigmatism, Myopia, Hyperopia
- Trial name
- CARDINAL (NCT01858701)
- Testing
- Lotrafilcon B toric contact lens, Comfilcon A toric contact lens
- Volunteers
- 49 people
- Sponsor
- Alcon Research