Clinical trials: Myopia; Refractive Error, open to volunteers
Myopia
Myopia Control Using Novel Soft Contact Lenses
The goal of this study is to investigate the myopic control efficacy of two study soft contact lenses in children. Participants will be prescribed Lens A, Lens B or single vision contact lenses for the first year.
- Trial name
- NCT07547085
- Testing
- Lens A, Lens B
- Where
- Hong Kong
- Volunteers
- 126 people
- Sponsor
- The Hong Kong Polytechnic University
Multimorbidity, Comorbidity
A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students
Junior high school students are in a critical period of physical and mental development, currently facing two major health challenges: first, persistently high rates of myopia with a noticeable trend toward younger onset; second…
- Conditions
- Multimorbidity, Comorbidity, Common Diseases in Children and Adolescents, Myopia
- Trial name
- NCT07237698
- Testing
- The intervention group participated in specialized physical education courses.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Wu
Myopia: Refractive Error
Evaluation of Novel Spectacles Intended for Myopia Management in a Short-Term Study
The primary objective of this study is to evaluate the visual acuity, wearability, and quality of vision with two novel multifocal glasses designs in habitual myopia control glasses wearers, in a non-dispensing study after…
- Trial name
- NCT07497672
- Testing
- Habitual myopia glasses, Myopia Glasses A, Myopia Glasses B
- Volunteers
- 20 people
- Sponsor
- Myoptechs, Inc
Myopia
Dual-focus Soft Contact Lenses for Controlling Rapid Progressive Myopia in Young Adults
This study aims to evaluate the effectiveness and acceptability of dual-focus soft contact lenses in controlling rapid myopia progression in adults through a randomized controlled trial.
- Trial name
- NCT06528860
- Testing
- MiSight® 1 day soft contact lenses, Proclear® 1 day soft contact lenses
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Refractive Errors
School-based Myopia Control Trial for Children With Premyopia or Myopia
This is a prospective, school-based randomized controlled trial designed to evaluate auricular acupressure combined with defocus spectacle lenses for myopia control in primary school students with premyopia or myopia.
- Trial name
- SPARK (NCT07746778)
- Testing
- Defocus Spectacle Lenses, Auricular Acupressure
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Multicenter Evaluation of Near Vision and Outdoor Time in Kids Study
Currently, optical and pharmacological interventions have been developed to prevent the progression of childhood myopia. However, no myopia control strategy has been shown to have complete efficacy in controlling myopia…
- Trial name
- MENOK (NCT06119243)
- Testing
- Vivior
- Where
- 5 sites in United States, Australia
- Volunteers
- 230 people
- Sponsor
- The University of New South Wales
Myopia
Influence of Rodenstock Spectacle Lenses on Myopia Progression.
The prevalence of myopia in Singapore is among the highest in the world, with 65 percent of our children being myopic by Primary 6, and 83 percent of young adults being myopic.
- Trial name
- NCT06816446
- Testing
- Myopia control spectacle lens, Single-vision lens
- Where
- Singapore
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Rodenstock GmbH
Myopia, Anisometropia
Assessing the Magnitude of Anisometropia in Patients Wearing Misight 1 Day Contact Lens
The effectiveness of Misight 1 Day Contact Lens in retarding anisometropic progression has not been investigated before. This study is aimed to elucidate the efficacy of Misight 1 Day Contact Lens for anisometropia control.
- Trial name
- NCT06744478
- Testing
- Misight 1 Day Contact Lens
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Myopia, Randomized Controlled Trial (RCT)
The Rebound Effect on Repeated Low-Level Red Light Therapy for Myopia
Myopia is a global public health issue, projected to affect 49.8% of the world population by 2050, increasing risks of cataracts, glaucoma, macular degeneration, and retinal detachment.
- Trial name
- NCT07748546
- Testing
- Repeated low-level red light (RLRL) therapy
- Volunteers
- 159 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Myopia
Repeatability of AO-SLO (Mona IIa) Technology and Cone Cell Density of Individuals Use Repeated Low-level Red-light Therapy
To explore the repeatability of AO-SLO (Mona IIa) technology and the difference of cone cell density between individuals who used or not used repeated low-intensity red light treatment
- Trial name
- AO-SLO (NCT07160036)
- Testing
- RLRL(Model RS-200-2A, Eyerising; Suzhou Xuanjia Optoelectronic Technology Co., Ltd., Suzhou, China))
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Ruihua Wei
Myopia, Refractive Errors
School-based Myopia Prevention Trial for Children With Adequate Hyperopic Reserve
This is a prospective, school-based randomized controlled trial designed to evaluate a wearable device-supported outdoor activity program for myopia prevention in primary school students with adequate hyperopic reserve.
- Conditions
- Myopia, Refractive Errors, Hyperopia
- Trial name
- SPARK (NCT07746752)
- Testing
- Wearable Device-Supported Myopia Prevention Program, Eye Health Education
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Astigmatism
Contoura With Phorcides Compared to Wavefront Optimized LASIK
Comparing post-operative visual acuity and patient reported satisfaction between Contoura with Phorcides and WaveLight Wavefront Optimized.
- Trial name
- NCT05486546
- Testing
- Contoura with Phorcides, WaveLight Wavefront Optimized
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- Daniel Terveen
Myopic Choroidal Neovascularisation, Anti-VEGF Treatment
The Treatment Burden of Myopic Choroidal Neovascularization
Pathologic myopia (PM) is characterized by progressive eye elongation associated with degenerative changes in the retinal and choroidal tissue.
- Conditions
- Myopic Choroidal Neovascularisation, Anti-VEGF Treatment, Burden
- Trial name
- mCNV burden (NCT07009574)
- Testing
- anti-VEGF intravitreal treatment in patients affected by myopic choroidal neovascularization
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Policlinico Gaspare Rodolico - San Marco Catania
Myopia
Efficacy of Repeated Low-level Red-light Therapy in Myopia Control
Low-level red-light technology provides a new and innovative myopia control approach. This strategy enables relatively high energies of light to be delivered at much shorter durations of exposure to induce the myopia control…
- Trial name
- NCT05606237
- Testing
- Low-level Red Light Therapy Device
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Presbyopia Correction, Visual Impairment and Blindness (Excl Colour Blindness)
Effect of Presbyopia Correction on Livelihood and Repayment Among Solar Customers in Western Region, Kenya
With age, people lose the ability to see things that are near them clearly. This is known as presbyopia. Although this is a normal ageing process, it can be corrected with near vision eyeglasses - colloquially known as reading…
- Conditions
- Presbyopia Correction, Visual Impairment and Blindness (Excl Colour Blindness), Repayment Behaviour, Livelihoods
- Trial name
- NCT06774183
- Testing
- Near vision glasses for presbyopia correction
- Volunteers
- 1,085 people
- Sponsor
- Dot Glasses Kenya
Myopia
Post-market Follow Up Study on Paragon CRT® 100 (Paflufocon D)
The main objective of this post market clinical study is to evaluate the effectiveness and safety of the Paragon CRT®100 Contact Lens.
- Trial name
- NCT04187599
- Testing
- Paragon CRT®100 Contact Lens
- Where
- 4 sites in China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Myopia, Ear Acupressure Pellets
Effects of Auricular Point Pressing With Pellets in Children With Insufficient Hyperopia Reserve
This project aims to address the trend of early onset and high myopia among children in China by focusing on insufficient hyperopia reserve, a key early warning indicator for myopia.
- Conditions
- Myopia, Ear Acupressure Pellets, Hyperopia Reserve, Low-concentration Atropine Eye Drops
- Trial name
- NCT07475585
- Testing
- Ear acupoint pressure pellet intervention group, Atropine intervention group, Joint intervention Group
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Refractive Errors
Measurment of Optic Disc Parameters, RNFL Thickness and Ganglion Cell Complex in Myopic, Hypermetropic and Emmetropic Patients Using OCT and Axial Length Measurments
To evaluate the optic disc parameters, thickness of ganglion cell complex (GCC), and thickness of peripapillary retinal nerve fiber layer (RNFL) in myopic and hyperopic and emmetrop patients using optical coherence tomography…
- Trial name
- NCT07241806
- Testing
- OCT
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intermittent Exotropia, Myopia
A Comparative Study of the Efficacy of Myopia Control Lenses With Different Mechanisms on Controlling Myopia Progression in Patients With Intermittent Exotropia
The goal of this clinical trial is to compare the efficacy of myopia control lenses with different working principles in patients with intermittent exotropia aged 6 to 12 years.
- Trial name
- NCT07642934
- Testing
- DIMS glasses, DOT glasses
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Myopia, Children
Atropine 0.01% Eyedrops for Evolutive Myopia Treatment in Children
Prevalence of myopia and its complications has been increasing over the past decades, especially among children and adolescents.
- Trial name
- NCT04252989
- Testing
- data collection
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne