Clinical trials: Musculoskeletal Pain, active
Subacromial Pain Syndrome, Rotator Cuff Related Shoulder Pain
Pain Phenotype and Response to Corticosteroid Injection in Patients With Subacromial Pain Syndrome (SAPS)
The goal of this prospective cohort study is to investigate whether pain phenotype is associated with subsequent change in pain intensity after corticosteroid injection given as part of routine care in patients diagnosed with…
- Conditions
- Subacromial Pain Syndrome, Rotator Cuff Related Shoulder Pain, Shoulder Pain, Shoulder Impingement Syndrome
- Trial name
- NAP SAPS CSI (NCT07792421)
- Testing
- Clinical evaluation
- Where
- Denmark
- Volunteers
- 134 people
- Sponsor
- Vejle Hospital
Subacromial Pain Syndrome, Rotator Cuff Related Shoulder Pain
Nociplastic Pain in Patients Diagnosed With Subacromial Pain Syndrome (SAPS)
The goal of this cross-sectional study is to estimate the prevalence of the nociplastic pain phenotype, according to the IASP clinical criteria, among patients diagnosed with SubAcromial Pain Syndrome (SAPS).
- Conditions
- Subacromial Pain Syndrome, Rotator Cuff Related Shoulder Pain, Shoulder Pain, Shoulder Impingement Syndrome
- Trial name
- The NAP SAPS (NCT07792434)
- Testing
- Clinical evaluation
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Vejle Hospital
Chronic Musculoskeletal Pain
Effectiveness of Communication-Focused Pain Neuroscience Education in Chronic Musculoskeletal Pain
This randomized controlled trial aims to evaluate the effectiveness of the "Algo(S)Therapy" Pain Neuroscience Education (PNE) program in patients with chronic musculoskeletal pain.
- Trial name
- NCT07001449
- Testing
- Pain Neuroscience Education with Communication Training, Pain Neuroscience Education without Communication Training, Usual Physiotherapy Treatment
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- University of Thessaly
Chronic Pain, Musculoskeletal Pain
Multicomponent Exercise and Pain Science Education for Fall Prevention in Older Adults With Chronic Musculoskeletal Pain (MovePainFall)
Chronic musculoskeletal pain is common in older adults and is associated with reduced mobility, loss of function, poorer quality of life, fear of movement, fear of falling and a higher risk of falls.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Accidental Falls, Fear of Falling
- Trial name
- MovePainFall (NCT07889024)
- Testing
- MovePainFall multicomponent exercise programme, Pain science and fall-prevention education
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Instituto Politécnico de Bragança
Myofacial Pain, Myofacial Pain Syndrome
Evaluation of the Effect of Adding Sodium Bicarbonate to Lidocaine in the Treatment of Myofascial Pain Syndrome
This study is designed to evaluate a method to improve the treatment of myofascial pain syndrome (MPS), a common condition that causes muscle pain, tenderness, and reduced movement due to the presence of trigger points in…
- Conditions
- Myofacial Pain, Myofacial Pain Syndrome, Myofacial Pain Syndromes, Trigger Point Pain, Myofascial
- Trial name
- BIC-LIDO-MPS (NCT07572994)
- Testing
- Lidocaine 2 %, Lidocaine + Sodium Bicarbonate
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Musculoskeletal Pain, Autonomy
Translation and Validation of the Limbs, Pain, Autonomy, Depression, Anxiety and Quality of Life Scales in Albanian
The cross-cultural adaptation will be performed according to the internationally recommended methodology, using the following guidelines: translation, back-translation; revision by a committee, questionnaire diffusion and data…
- Conditions
- Musculoskeletal Pain, Autonomy, Healthy, Upper Limb Injury
- Trial name
- NCT06685094
- Where
- Spain
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Musculoskeletal Pain
Musculoskeletal Outcomes Using Tylenol/Ibuprofen vs. Oral Steroids in New Injuries
In this pilot study, the investigators aim to compare two short-term pain relief methods administered over the course of 6 days in the setting of acute musculoskeletal (MSK) pain: 1.
- Trial name
- MOTION (NCT07393503)
- Testing
- Methylprednisolone 4Mg Tab, Acetaminophen 500Mg Tab, Ibuprofen 200Mg Oral Tablet
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- State University of New York at Buffalo
Juvenile Idiopathic Arthritis (JIA), Fibromyalgia
Biopsychosocial Risk Influences on the Development and Generation of Early-Onset Chronic Pain
The purpose of the study is to discover the underlying subtypes of chronic musculoskeletal pain (muscle and joint pain) in youth.
- Conditions
- Juvenile Idiopathic Arthritis (JIA), Fibromyalgia, Lupus, Scoliosis
- Trial name
- BRIDGE Pain (NCT07602595)
- Testing
- Not applicable- observational study
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Musculoskeletal Pain
Virtual Reality and Standard Care vs. Standard Care Alone for Acute MSK Pain in Geriatric ED Patients
The proposed Virtual Reality as an Adjunct to Pain Management for Geriatric Patients in the ED (VRAP-ED) project will take place in the Emergency Medicine Department at Maimonides Medical Center.
- Trial name
- NCT06685107
- Testing
- Standard of Care Analgesia, Standard of Care Analgesia + Virtual Reality
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Antonios Likourezos
Older People, Pain
Exploring the Acute and Dynamic Relationships Between Movement and Pain in Older Adults With Musculoskeletal Pain
The purpose of this research study is to evaluate the effect of brief bouts of intermittent walking on bodily pain, pain during movement, and how the body adapts to musculoskeletal pain in older adults.
- Trial name
- NCT06886906
- Testing
- Intermittent light walking, uninterrupted sitting
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Indiana University
Chronic Musculoskeletal Pain, Sexual Assault
Post-traumatic Estradiol Administration and Care Evaluation (PEACE)
This pilot randomized, double-blind, placebo-controlled trial evaluates the feasibility, acceptability, and tolerability of administering a single 6 mg oral dose of 17β-estradiol (E2) to individuals assigned female at birth who…
- Conditions
- Chronic Musculoskeletal Pain, Sexual Assault, Posttraumatic Stress Disorder (PTSD)
- Trial name
- PEACE (NCT07868536)
- Testing
- 17β-estradiol
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Myofascial Trigger Points, Migraine
Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Knee Osteoarthritis(OA)
Chronic musculoskeletal pain (CMP) is a common disease in China, with a high incidence among the elderly, and has a significant impact on patients' quality of life. Knee osteoarthritis is a common type of CMP.
- Conditions
- Myofascial Trigger Points, Migraine, Cervicogenic Headache, Chronic Musculoskeletal Pain
- Trial name
- NCT07347028
- Testing
- MTrPs Injection, Intra-articular(IA) Injection
- Where
- China
- Volunteers
- 238 people
- Sponsor
- Beijing Tiantan Hospital
Orthopaedic Fractures, Orthopaedic Trauma Fractures and Non-unions
Mindfulness in Fracture Recovery and Reduction of Opioid Reliance: Evaluating the Feasibility of Implementing a Brief, Mindfulness-based Intervention to Manage Pain and Anxiety Before and After Fracture Surgery
Breaking a bone is not only physically painful but also emotionally overwhelming. Patients often experience intense pain, anxiety, and uncertainty as they are rushed to hospital, undergo emergency treatment, and prepare for…
- Conditions
- Orthopaedic Fractures, Orthopaedic Trauma Fractures and Non-unions, Orthopaedic Trauma, Orthopaedic Surgery
- Trial name
- MIRROR (NCT07486505)
- Testing
- Mindfulness Based Intervention, Educational Recording
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS)
Regenerative Medicine for Joint Hypermobility and Instability
This clinical trial is designed to evaluate whether a stepwise injection-based treatment approach can reduce pain and improve function in adults with joint hypermobility, connective tissue laxity, and joint instability.
- Conditions
- Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS), Joint Hypermobility, Joint Instability
- Trial name
- NCT07688096
- Testing
- Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational)
- Volunteers
- 100 people
- Sponsor
- Manhattan Pain Medicine, PLLC
Work-Related Musculoskeletal Disorders
Exercise and Health Education for Musculoskeletal Health in Industrial Workers
This prospective, non-randomised interventional study aims to assess changes in musculoskeletal health, pain and physical activity among industrial workers following a health education and exercise programme adapted to their…
- Trial name
- NCT07844707
- Testing
- Health Education, Tailored Exercise Programme
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Hyperthermia, Chronic Primary Pain
Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked Pain
This study, in a quasi-experimental matched two-group pre-post design, investigates the effect of serial water-filtered whole-body hyperthermia on circadian core body temperature, the somatosensory system (nociception) and the…
- Conditions
- Hyperthermia, Chronic Primary Pain, Widespread Pain, Muscular Disease
- Trial name
- HYPPRI-1 (NCT07101978)
- Testing
- serial whole body hyperthermia
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Chronic Pain, Musculoskeletal Pain
Weighted Blanket Use for Adults With Chronic Pain
Chronic pain is a common condition that can affect sleep, daily functioning, and overall quality of life. Many individuals living with chronic pain seek non-medication approaches to help manage their symptoms.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Sleep Disturbance, Pain Disorders
- Trial name
- EMBRACE (NCT07498491)
- Testing
- Weighted Blanket
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National University of Natural Medicine
Chronic Low Back Pain, Musculoskeletal Pain
Veterans' Intervention Blending NeuRomodulation and YogA for Chronic Low BackPaiN Treatment: VIBRANT
The objectives of this VA Merit application are to demonstrate efficacy of combined intermittent theta burst (iTBS) and yoga (iTBS+yoga) intervention on improving pain, function, analgesic use, self-efficacy, quality of life and…
- Trial name
- VIBRANT (NCT07158567)
- Testing
- intermittent theta burst stimulation, LoveYourBrain Yoga Program
- Where
- 2 sites in United States
- Volunteers
- 213 people
- Sponsor
- VA Office of Research and Development
Morbid Obesity Requiring Bariatric Surgery, Neck Pain Musculoskeletal
Changes in Cervical Posture, Cervical Function, and Neck Pain After Sleeve Gastrectomy
Obesity may contribute to neck pain, altered cervical posture, and impaired cervical function through increased mechanical loading, changes in body alignment, and reduced muscle performance.
- Trial name
- NCT07813429
- Testing
- Laparoscopic Sleeve Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital