Clinical trials: Musculoskeletal Function
Pain, Osteoarthritis, Hip
Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the Knee
This clinical trial tests the pain relieving effectiveness of OROS hydromorphone, a once-daily formulation of a strong opioid against placebo in patients, who are suffering from pain due to osteoarthritis of the hip or the knee…
- Conditions
- Pain, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT00980798
- Testing
- OROS hydromorphone HCl
- Where
- 12 sites in Czechia, Romania and 2 more
- Volunteers
- 288 people
- Sponsor
- Janssen-Cilag International NV
Knee Osteoarthritis
The Efficacy of Exercise and Alternative Applications of NMES on Pain and Function in Patients With Knee OA
The aim of the study was to investigate the efficacy of exercise and different size electrodes of neuromuscular electrical stimulation (NMES) applications on pain, range of motion (ROM), muscle strength, function status and…
- Trial name
- NCT03571698
- Testing
- Neuromuscular Electrical Stimulator
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Plantar Fasciitis
Efficacy of a Custom Temporary Foot Orthosis for Plantar Fasciitis Treatment
The aim of this randomized control trial is to identify the possible effectiveness of the temporary use of an inexpensive, custom-made plantar fascia orthotic (PFO).
- Trial name
- NCT01882894
- Testing
- Custom PFO, Faux orthosis
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Puget Sound
Post-thoracotomy Pain Syndrome, Shoulder Pain
The Effect of Mirror Therapy After Thoracotomy
After thoracotomy, limitation in shoulder functions, ipsilateral shoulder pain, decrease in shoulder muscle strength and deterioration in quality of life occur.
- Trial name
- NCT05962736
- Testing
- Mirror therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Akdeniz University
Healthy Japanese Individuals
Verification Study of the Effects of Consumption of the Test Food on the Musculoskeletal System
The goal of this clinical trial is to test the effects of the test products on the locomotor system in healthy Japanese adults with low muscle mass and knee joint discomfort.
- Trial name
- NCT07729657
- Testing
- Food containing NAG and HA, Food containing NAG
- Where
- 2 sites in Japan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bloomage Biotechnology Corp., Ltd.
Lumbar Spondylosis
An Immediate Functional Progression Program for Adolescent Athletes With Spondylolysis
Spondylolysis, a stress fracture in the pars interarticularis of a lumbar vertebra, is the most common identifiable cause of low back pain (LBP) in adolescent athletes, occurring in 14-30% of athletes who experience LBP.
- Trial name
- NCT05505981
- Testing
- Immediate PT, Rest until pain resolves
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Nationwide Children's Hospital
Muscle Spasticity
Muscle Ultrasound Measures as Biomarkers of Upper Motor Neuron Function
Background: Primary lateral sclerosis (PLS) is a rare disease. It leads to weakness in the muscle of the arms, legs, and face. People with PLS develop muscle stiffness called spasticity.
- Trial name
- NCT02408900
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Knee Osteoarthritis
Evaluation of an Educational Program Associated With Exercises (EDEX) Before Total Knee Arthroplasty
The purpose of this study is to determine whether a standardized education and exercise program proposed before a total knee replacement for knee osteoarthritis is effective in functional recovery after surgery.
- Trial name
- EDEX (NCT01671917)
- Testing
- Educational and exercise program, Usual care
- Where
- France
- Volunteers
- 262 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bone Neoplasm, Metastatic Malignant Neoplasm in the Bone
Intraoperative Neuromonitoring of Sacral Reflexes to Predict Post Operative Function in Patients Undergoing Sacrectomy for Pelvic Bone Malignancy or Patients Undergoing Spinal Procedures Without Sacral Root Involvement
This clinical trial tests how well monitoring the sacral reflexes during surgery (intraoperatively) works to predict the post operative function for patients undergoing removal of the lowest part of the spine (sacrectomy) for…
- Trial name
- NCT07707024
- Testing
- Intraoperative Nerve Monitoring, Surgical Procedure, Survey Administration
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- City of Hope Medical Center
Knee Arthropathy
Effect of Pre-op Patient Education on Functional Outcomes After TKA
This study aims to evaluate the effect of preoperative patient education program on functional mobility, gait, postural control, and kinesiophobia level in subjects with TKA.
- Trial name
- NCT03230942
- Testing
- Pre-operative education, Pos-operative rehabilitation
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of the State of Santa Catarina
Temporomandibular Joint Dysfunction Syndrome, Forward Head Posture
Efficacy of Scapulothoracic Exercises on Postural Stability, Proprioception, Muscular Features and Mandibular Functions
The goal of this Randomized, Double-Blind, Clinical Trial is to investigate the effects of scapulothoracic exercises on postural stability, muscle strength, muscular endurance, mandibular functions and proprioception in sedentary…
- Trial name
- NCT05966103
- Testing
- Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Cyprus International University
Knee Osteoarthritis
Comparison of Functional Recovery After Total Knee Arthroplasty Between Low Phase Angle and High Phase Angle Group
The goal of this observational study is to compare the functional outcome of patients with end-stage knee osteoarthritis (OA) before and after total knee arthroplasty based on the phase angle level.
- Trial name
- NCT06701474
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Patellofemoral Pain Syndrome
Comparative Effects of Perturbation and Functional Stabilization Training on Patellofemoral Pain Syndrome
The main objective of this study is to determine the comparative effects of perturbation and functional stabilization training on pain, balance, and performance in athletes with patellofemoral pain syndrome(PFPS).
- Trial name
- NCT06511362
- Testing
- Functional stabilization training, perturbation exercises
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Fibromyalgia
Effect of tDCS in Intrinsic Functional Brain Connectivity Assessed by Functional Magnetic Resonance in Fibromyalgia
Considering the central component of fibromyalgia (FM), the focus of research on current therapeutic approaches has been techniques that may modify the dysfunctional neuroplasticity process, such as transcranial direct current…
- Trial name
- NCT03841227
- Testing
- Active-tDCS
- Where
- 2 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Distal Radius Fractures
Functional Outcome Following Fracture of the Distal Radius
Patients attending the University Hospital Coventry UK with a broken wrist requiring an operation, will be invited to enter the study.
- Trial name
- NCT01435070
- Testing
- Kirschner wire fixation, Volar Locking Plate fixation
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Warwick
Osteoarthritis, Knee
An Acupuncture Functional Magnetic Resonance Imaging (fMRI) Study on Chronic Pain: Response Reliability and Dose Effect
In this proposal, we plan to dynamically investigate brain response to verum acupuncture (of two different "doses") and placebo acupuncture, using a paradigm that approximates clinical acupuncture practice across multiple…
- Trial name
- NCT01079390
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Massachusetts General Hospital
C10.228.140.140.254
The Socioeconomic Status and Child Characteristics on the Physical Therapy Outcome in Children With Spastic Cerebral Palsy
The main outcome of physical therapy interventions is the progress of gross motor functions which result from the interactions between many factors not limited to physical, medical or surgical interventions but also including…
- Trial name
- NCT04160403
- Testing
- physical therapy intervention
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zeinab Hussein
Coxarthrosis, Avascular Necrosis of Hip
Effect of Peri-operative Glucocorticoids on Short-term Functional Outcome After THA
This randomized, single surgeon, placebo controlled, double blind study will be conducted in order to investigate whether or not peri-operative high doses of intravenous glucocorticoids improve short-term functional outcome after…
- Trial name
- DEXA (NCT04317872)
- Testing
- High dose of peri-operative intravenous dexamethasone, Low dose of peri-operative intravenous dexamethasone
- Where
- Belgium
- Volunteers
- 71 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity (Disorder), Obesity
Effect of Vitamin D on Body Composition and Functionality of Older Adults
Older adults with obesity often experience a gradual loss of muscle mass and muscle strength, a condition sometimes described as sarcopenic obesity.
- Conditions
- Obesity (Disorder), Obesity, Sarcopenia, Sarcopenia in Elderly
- Trial name
- NCT07275177
- Testing
- Vitamin D
- Where
- Mexico
- Volunteers
- 29 people
- Sponsor
- Universidad Autónoma Benito Juárez de Oaxaca
Muscle Weakness, Syndrome; Institutionalization
Respiratory Muscle Training in Institutionalized Elderly Population
The global loss of muscle mass and strength associated with aging is a cause of functional impairment and disability, particularly in the frail elderly.
- Conditions
- Muscle Weakness, Syndrome; Institutionalization, Other Diagnoses, Comorbidities, and Complications
- Trial name
- NCT01624272
- Testing
- Threshold® Inspiratory Muscle Trainer (Respironics® Health Scan Inc. Cedar Grove, NJ, USA)., Yoga Pranayama breathing exercises
- Where
- 3 sites in Spain
- Volunteers
- 71 people
- Sponsor
- University of Valencia