Clinical trials: Musculoskeletal Discomfort
Hypermobility, Joint, Hypermobility Syndrome
Exercise in Patients With Hypermobile Joints and Knee Pain
Pain associated with knee joint hypermobility is common in the adult population, but evidence on treatment is sparse. This study investigates if high-load resistance training is superior to usual care in improving…
- Conditions
- Hypermobility, Joint, Hypermobility Syndrome, Knee Discomfort
- Trial name
- HIPEr-Knee (NCT06277401)
- Testing
- Neuromuscular training for the knee, High-load strength training for the knee
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Knee Injuries, Cartilage Injury
Clinical Study of Chondro-Gide® for Large Chondral Lesions in the Knee
Multi-center, prospective, concurrently controlled, non-randomized, double-blind (patient and assessor). Treatment of large chondral lesions in the knee with microfracture plus the Chondro-Gide® ACC is non-inferior to treatment…
- Conditions
- Knee Injuries, Cartilage Injury, Cartilage Disease, Knee Discomfort
- Trial name
- SECURE (NCT04537013)
- Testing
- Microfracture, Microfracture plus placement of Chondro-Gide® ACC
- Where
- 15 sites in United States, Canada and 1 more
- Volunteers
- 82 people
- Sponsor
- Geistlich Pharma AG
Musculoskeletal Diseases or Conditions
Ergonomic Benefits From Robotically Assisted Laparoscopy for Hysterectomies and Other Indications
This is a prospective, single-center, observational clinical trial at the Department of Women's Health of the University Hospital Tübingen.
- Trial name
- ERCON (NCT06109753)
- Testing
- Robotically Assisted Laparoscopic Surgery, Conventional Laparoscopic Surgery
- Where
- Germany
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Joint Discomfort, Musculoskeletal Pain
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of resO™ Bone and Joint Support Postbiotic on Physical Function, Pain Interference, and Mobility in Adults With Joint Discomfort
This randomized, double-blind, placebo-controlled study evaluates the effects of resO™ Bone and Joint Support Postbiotic on physical function, pain interference, mobility, and recovery in adults aged 18-75 years experiencing…
- Conditions
- Joint Discomfort, Musculoskeletal Pain, Mobility Limitation
- Trial name
- RESO101 (NCT07602426)
- Testing
- Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Able Biolabs, LLC
Joint Discomfort, Joint Pain, Stiffness, Function
JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women
The goal of this interventional study is to evaluate whether the study product can help improve quality of life and reduce common menopause symptoms-such as joint discomfort, hot flashes and night sweats-in women aged 50-70.
- Conditions
- Joint Discomfort, Joint Pain, Stiffness, Function, Joint Pain, Hot Flashes
- Trial name
- NCT07238478
- Testing
- JDS-HF3.0
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Bonafide Health
Neuralgia, Myalgia
Safety and Efficacy of Cunermuspir on Energy, Strength, and Fatigue in Patients With Nerve or Muscle Pain
Male and female participants were selected based on chronic neuromuscular pain. Patients were instructed to take two doses of the placebo or cuprous nicotinic acid chelate Cunermusmir twice a day for 28 days.
- Trial name
- NCT04737278
- Testing
- Cunermuspir
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- Mitosynergy LLC
Joint Pain
NAtive Collagen Type II In Healthy VoluntEers With Joint Discomfort
Collagen Supplement is a natural ingredient that contains native collagen derived from chicken sternum. Collagen Supplement is efficacious and safe on healthy subjects as compared to placebo.
- Trial name
- ACTIVE (NCT05282992)
- Testing
- Native type II collagen
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Knee Arthritis, Knee Osteoarthritis
Gold Factor on Knee Joint Health and Function
The purpose of this clinical study was to determine whether gold nanoparticles (AuNP) supplement holds clinical value in improving joint health, function, and quality of life for arthritis patients.
- Conditions
- Knee Arthritis, Knee Osteoarthritis, Knee Pain Chronic, Knee Discomfort
- Trial name
- NCT05347602
- Testing
- Gold Factor (Gold Nanoparticles, AuNPs)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- 4Life Research, LLC
Shoulder Pain
Effect of Intravenous Dexmedetomidine on Patient Discomfort in Laparoscopic Cholecystectomy Under Spinal Anesthesia.
Laparoscopic cholecystectomy (LC) has been routinely performed under general anesthesia despite the several disadvantages of general anesthesia compared to regional anesthesia.
- Trial name
- RCT (NCT04115449)
- Testing
- Dexmedetomidine, normal saline
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Joint Pain
Clinical Study to Evaluate the Effect of Different Doses of UC-II® Supplementation on the Range of Motion & Joint Discomfort in Healthy Subjects
A Randomized, Double-Blind, Placebo-controlled, Parallel Design Clinical Study to Evaluate the Effect of Different Doses of UC-II® Supplementation on the Range of Motion \& Joint Discomfort in Healthy Subjects
- Trial name
- NCT05212259
- Testing
- Collagen type II (40 mg/day), Collagen type II (80mg/day), Collagen type II (120 mg/day)
- Where
- 10 sites in India
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Menopause, Menopausal Hormone Therapy
A Retrospective and Prospective Clinical Registry for Data Collection of Perimenopausal, Menopausal and Premature Ovarian Insufficiency Women
This study is designed as on observational, retrospective, and prospective clinical registry aimed at collecting comprehensive real-world data on women in perimenopause, menopause, and with premature ovarian insufficiency (POI)…
- Conditions
- Menopause, Menopausal Hormone Therapy, Menopause Surgical, Menopause Related Conditions
- Trial name
- NCT07606326
- Volunteers
- 5,000 people
- Sponsor
- IRCCS San Raffaele
Crossbite, Maxillary Hypoplasia
Pain and Discomfort During Maxillary Expansion
The aim of the present study is to investigate and analyze the perception of pain and function impairment during the first week of activation with two different palatal expansion screw to identify an effective pain prevention…
- Trial name
- NCT03757468
- Testing
- orthodontic - maxillary expansion
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Genova
Musculoskeletal Pain
Combined Effects of Exercise Breaks and Rest Breaks on Fatigue and Musculoskeletal Discomfort in Static Workstation Office Workers
Musculoskeletal discomfort and work fatigue has enormous impact on quality of personal and professional life and increases health related economic burden on country due to increased cost of healthcare and reduced productivity in…
- Trial name
- NCT05337579
- Testing
- Supplemental Micro Breaks, Exercise Breaks
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Pain, Discomfort
Association Among Pain Perception, Severity of Temporomandibular Joint Dysfunction, and Spinal Health in Caregivers of Stroke Individuals
This study aims to examine pain perception, temporomandibular disorder severity and spine health in caregivers of stroke patients.
- Conditions
- Pain, Discomfort, Caregiver, Temporomandibular Disorder
- Trial name
- NCT06052735
- Testing
- Correlation research
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Clubfoot
Sucrose Analgesia in Infants Undergoing Casting for Club Foot
Babies with congenital clubfeet are treated by the Ponseti casting method. The procedure may cause discomfort to the patient. This study will examine the use of 5 CC Sucrose solution as a comforting agent for the babies.
- Trial name
- SCF (NCT01050088)
- Testing
- sucrose solution, Saline
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Rabin Medical Center
Stress, Resilience and Mental Health of First Responders
Mindfulness in Motion Targeted to Sustaining the Mental and Physical Resilience of First Responders
High levels of chronic and recurrent workplace stress can profoundly impact the physical, mental, and emotional health of first responders.
- Conditions
- Stress, Resilience and Mental Health of First Responders, Work Engagement, Musculoskeletal Discomfort
- Trial name
- NCT07502092
- Testing
- Mindfulness in Motion for First Responders
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Occupational Injuries, Occupational Exposure
The Effect of Intelligent Exercise and Ergonomic Recommendations on Surgeon Musculoskeletal Discomfort
The goal of this clinical trial is to investigate the effects of Intelligent Physical Exercise Training (IPET) and ergonomic recommendations on musculoskeletal pain among abdominal and pelvic surgeons.
- Trial name
- NCT06112106
- Testing
- Intelligent Physical Exercise Training (IPET)
- Where
- 7 sites in United States, Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Musculoskeletal Discomfort, Work-related Vigor
AI-Powered Micro-Breaks at Work
This study evaluates the feasibility of an online intervention based on artificial intelligence-the Movebite app integrated into the Slack platform-aimed at promoting engagement in micro-breaks involving physical activity, with…
- Trial name
- NCT07209553
- Testing
- Mobi
- Where
- Romania
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- West University of Timisoara
Low Back Pain
Active Break Intervention on Low Back Pain and Musculoskeletal Discomfort During Prolonged Sitting Among Young People
The most recent evidence showed that the COVID-19 (coronavirus disease 2019, National Institutes of Health) pandemic caused an increase in low back pain (LBP) prevalence and intensity among young people.
- Trial name
- NCT05810519
- Testing
- Active break with the proposed lumbar and hip extension exercises, Self-care recommendations
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- Józef Piłsudski University of Physical Education
Osteoarthritis, Knee, Osteoarthritis
A Study of the Feasibility of Using the Dietary Supplement "ARTNEO" in Patients With Osteoathritis
The goal of this clinical study is to evaluate the effectiveness of the properties that support the functional state of the joints and the safety of the dietary supplement for food ARTNEO®, oral capsules, in patients with stage…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Knee Osteoarthritis, Knee Arthritis
- Trial name
- NCT05975879
- Testing
- undenaturated collagen type II, methylsulfonylmethane, boswellia serrata, vitamin D3 (cholecalciferol), vitamin C (ARTNEO)
- Where
- 12 sites in Russia
- Volunteers
- 212 people
- Sponsor
- NPO Petrovax