Clinical trials: Musculoskeletal
Hand Injuries and Disorders, Neurological Conditions
3D Hand Orthosis Trial
In people with chronic hand conditions, hand orthoses are frequently prescribed to improve performance in activities of daily living (ADL).
- Conditions
- Hand Injuries and Disorders, Neurological Conditions, Neuromuscular Diseases (NMD), Musculoskeletal Conditions (e.g., Tendinitis, Capsulitis)
- Trial name
- NCT07633821
- Testing
- 3D-printed hand orthosis (intervention), Conventional hand orthosis (control)
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Shoulder Musculoskeletal Disorders
Development and Validation of Acceptance Questionnaire for The Use of Virtual Reality in Upper Limb Rehabilitation
The development of an Arabic questionnaire to assess acceptance of VR in upper limb rehabilitation would include adapting Technology Acceptance Model TAM, followed by panel review for content validity.
- Trial name
- NCT07850830
- Testing
- Physical rehabilitation using virtual reality
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Mahmoud Aboraya
Musculoskeletal Diseases, Mental Disorder
Expert@Work - Effectiveness of a Digital Expert Team on Return to Work
Long-term sick leave is a challenge in Norway, and the healthcare and labor- and welfare services are often not coordinated in helping the sick-listed employees return to work.
- Trial name
- Expert@Work (NCT05575908)
- Testing
- Digital expert team
- Where
- 4 sites in Norway
- Volunteers
- 170 people
- Sponsor
- St. Olavs Hospital
Morbid Obesity Requiring Bariatric Surgery, Neck Pain Musculoskeletal
Changes in Cervical Posture, Cervical Function, and Neck Pain After Sleeve Gastrectomy
Obesity may contribute to neck pain, altered cervical posture, and impaired cervical function through increased mechanical loading, changes in body alignment, and reduced muscle performance.
- Trial name
- NCT07813429
- Testing
- Laparoscopic Sleeve Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Neck Pain Musculoskeletal, Chronic Neck Pain
Clinical and Brain Activity Assessment Before and After Physiotherapy in People With Chronic Non-specific Neck Pain
The goal of this clinical trial is to investigate whether electroencephalographic features are associated with the multidimensional clinical characteristics of adults with chronic non-specific neck pain and whether clinical and…
- Trial name
- NCT07756229
- Testing
- Manual physiotherapy and neck-specific exercise programme
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ander Cervantes Benítez
Insomnia, Healthy Adult
The Impact of Acute Pain on Sleep Parameters in the Insomnia Population and Healthy Controls
This study investigates how acute exercise-induced muscular pain affects sleep quality and sleep architecture in people with insomnia compared to healthy sleepers.
- Conditions
- Insomnia, Healthy Adult, Sleep, Musculoskeletal Pain
- Trial name
- NCT07826650
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Insomnia, Healthy Adult
The Impact of Insomnia on Pain Sensitivity and the Trajectory of Exercise-induced Muscular Pain
Sleep is a critical determinant of physiological recovery and pain regulation. Growing evidence suggests that sleep disruption directly heightens central and peripheral pain sensitivity to sensory stimuli (e.g., mechanical…
- Conditions
- Insomnia, Healthy Adult, Musculoskeletal Pain, Pain Sensitivity
- Trial name
- NCT07827664
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Musculoskeletal Disorder
Early Identification of Risk for and Prevention of Sickness Absence Due to Musculoskeletal Pain - an RCT
Background: Musculoskeletal pain is a leading cause of disability in the world. Although the majority of musculoskeletal-related pain conditions, such as low back pain, often resolves spontaneously, pain may recur or persist over…
- Trial name
- PREVSAM (NCT03913325)
- Testing
- PREVSAM model, Treatment as usual (standard treatment)
- Where
- Sweden
- Volunteers
- 254 people
- Sponsor
- Vastra Gotaland Region
Orthopedic Disorder, Trauma Injury
X-BS Ortho Bone Graft Study
Randomised investigation of the osteoconductive performance and safety of CE-marked FDBS bone graft (GraftR3®), with contextual reference to CE-marked IBS (MBCP® Putty), in the filling of orthopaedic bone defects.
- Conditions
- Orthopedic Disorder, Trauma Injury, Extremity Injury
- Trial name
- NCT06326827
- Testing
- FDBS (GraftR3®), IBS (MBCP® Putty)
- Volunteers
- 200 people
- Sponsor
- Advanced Medical Solutions Ltd.
Musculoskeletal Diseases
Translation, Cultural Adaptation, and Standardization of E-NMQ
The primary objective of this study is to translate the Nordic Musculoskeletal (E-NMQ) Questionnaire Modified Version into Urdu following international guidelines.
- Trial name
- NCT07626619
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Riphah International University
Musculoskeletal Pain, Physical Activity
Physical Activity in Lawyers: Factors Affecting Musculoskeletal Pain
This study aims to determine the prevalence and distribution of musculoskeletal pain among lawyers registered with the Isparta Bar Association, specifically in relation to their varying levels of physical activity.
- Conditions
- Musculoskeletal Pain, Physical Activity, Burnout, Professional
- Trial name
- NCT07827937
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Musculoskeletal Injury, Frailty
Exercise Engagement in People Over 60 at Risk of Falls
It is a qualitative study, using semi structured interviews to explore patient's experiences of falls and their perceptions on facilitators and barriers to exercise.
- Conditions
- Musculoskeletal Injury, Frailty, Physical Inactivity, Health Behavior
- Trial name
- NCT06100445
- Testing
- Semi structured interviews
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Noonan Syndrome
A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment
The purpose of this study in children with Noonan syndrome is to evaluate the effect of 3 doses of vosoritide on growth as measured by AGV after 6 months of treatment.
- Trial name
- NCT06668805
- Testing
- Vosoritide Injection
- Where
- 38 sites in United States, Australia and 5 more
- Volunteers
- 30 people
- Sponsor
- BioMarin Pharmaceutical
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS)
Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test
The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon problems, or nerve compression).
- Conditions
- Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis
- Trial name
- NCT07158892
- Testing
- Diagnostic Advance Care Planning Discussion, Informational Statement Only
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Texas at Austin
Neck Pain, Neck Pain Musculoskeletal
Sleep Hygiene Plus Physiotherapy for Sleep and Disability in Chronic Neck Pain
This study investigates the effectiveness of a combined intervention that integrates sleep hygiene education with physiotherapy exercises in patients suffering from chronic neck pain.
- Conditions
- Neck Pain, Neck Pain Musculoskeletal, Sleep Disturbances, Fatigue, Mental
- Trial name
- NCT07178496
- Testing
- Sleep Hygiene Techniques, conventional physiotherapy program, Control arm
- Where
- Palestinian Territories
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Musculoskeletal Infection, Chronic Rhinosinusitis (Diagnosis)
Establishing Personalized Phage Therapy and Its Comparative Cost in Difficult-to-treat Infections (EPHICACI)
EPHICACI is a multicenter, prospective study that continues and expands the monocentric PHAGEFORCE registry initiated at UZ Leuven.
- Conditions
- Musculoskeletal Infection, Chronic Rhinosinusitis (Diagnosis), Persistent Bacteremia, Pulmonary Infection
- Trial name
- EPHICACI (NCT06368388)
- Testing
- Prospective data collection phage therapy, Prospective data collection standard-of-care
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
X-linked Hypophosphatemia
A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia
A first-in-human study of KK8123 in adults with X-linked hypophosphatemia.
- Trial name
- NCT06525636
- Testing
- KK8123
- Where
- 10 sites in United States, Canada and 3 more
- Volunteers
- 39 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Fibromyalgia, Chronic Low Back Pain
Mapping Stress and Pain Interactions (G072323N)
The over-arching goal of this observational (case-control, with a cross-sectional and longitudinal arm) study is to comprehensively map stress system (dys)function (including reactivity and recovery) in people with primary…
- Conditions
- Fibromyalgia, Chronic Low Back Pain, Subacute Low Back Pain
- Trial name
- STRAIN (NCT06892977)
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Ghent
Patellar Tendinitis, Jumper's Knee
Identification of Kinematic Variables Specific of Patellar Tendinopathy in Athletes at Risk
This research aims to identify and monitor specific kinematic markers associated with patellar tendinopathy in athletes at risk.
- Conditions
- Patellar Tendinitis, Jumper's Knee, Musculoskeletal Injuries, Knee Injuries
- Trial name
- TENVOL (NCT07406516)
- Testing
- The intervention consists of a series of vertical jump tests captured using high-resolution cameras with markerless motion capture technology., The intervention consists of a series of vertical jump tests captured using high-resolution cameras with markerless motion capture technology at 6 months and 12 months
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Musculoskeletal Pain, Osteoarthritis
Integrated Healthy Lifestyle and Pain Care for People With Musculoskeletal Conditions Living in Rural Areas.
This study aims to compare the effects of an in-person physiotherapist-led lifestyle-focused pain care intervention with a virtual multidisciplinary lifestyle-focused pain care intervention on pain impact in people with…
- Conditions
- Musculoskeletal Pain, Osteoarthritis, Low Back Pain
- Trial name
- HeLP-R (NCT07173335)
- Testing
- In-person physiotherapist led integrated healthy lifestyle and pain care, Virtual multidisciplinary integrated healthy lifestyle and pain care
- Where
- 3 sites in Australia
- Volunteers
- 354 people
- Sponsor
- University of Sydney