AzTrials
AzTrials

Musculoskeletal DiseasesNCT07626619

Translation, Cultural Adaptation, and Standardization of E-NMQ

An observational study of Musculoskeletal Diseases, run by Riphah International University at 1 site in Pakistan.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

The primary objective of this study is to translate the Nordic Musculoskeletal (E-NMQ) Questionnaire Modified Version into Urdu following international guidelines. Presently, there exists no validated tool to comprehensively measure symptoms such as pain, stiffness and weakness in Urdu-speaking patients in Pakistan. Read more about this study

Who is it for?
Ages 20 to 45 years
Conditions the study is for
Musculoskeletal Diseases
How many people
110 participants
Where
1 sitePakistan
Study dates
1 Aug 2026to 1 Nov 2026
Phase
Observational
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 20 to 45 years
  • All sexes
  • Adult

Study population: ndividuals with a condition affecting the musculoskeletal system

Who may be able to join

  • Age between 18 and 45 years.
  • Both male and females
  • Able to speak and read Urdu language Individuals with a condition affecting the musculoskeletal system
  • Age matched healthy individual recruited will be either the attendants/family members accompanying patients in Jinnah Hospital or employees of Riphah International University.

Who cannot join

  • Pregnant females, inflammation, local infection, fracture, suspected tumor, Recent surgery
  • Unwilling patients
  • Cognitive impairment \& speech impairment
  • Any neurological diseases (reflex changes \& loss of sensation)

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Imran Amjad, PhD contact

03324390125

Imran.amjad@riphah.edu.pk

Pakistan1 site, 1 recruiting

  • Ghurki Hospital Lahore

    Lahore, Punjab Province, 54000

    Khansa Najam, MSOMPT

    Recruiting

Other trials in Pakistan

About this study

Official title: Translation, Cultural Adaptation, and Standardization of the Extended Version of the Nordic Musculoskeletal Questionnaire (E-NMQ) for the Urdu-Speaking Population

The primary objective of this study is to translate the Nordic Musculoskeletal (E-NMQ) Questionnaire Modified Version into Urdu following international guidelines. Presently, there exists no validated tool to comprehensively measure symptoms such as pain, stiffness and weakness in Urdu-speaking patients in Pakistan. Specifically, the widely used E-NMQ, having these three vital categories, has yet to be translated and validated for Urdu-speaking individuals with musculoskeletal disease (MSD).

Read the detailed description

To find the reliability and validity of the Urdu version of E-NMQ in patients of MSD, procedure involves following stages: E-NMQ will be adapted in Urdu and then back translated in English, then will be first tested for its content validity by using the content validity index. Then Urdu version of the E-NMQ will be pilot run; tested for its validity and reliability. In next step Urdu version of the E-NMQ will be tested for its validity and reliability in patients with MSD.

Keywords
Cultural Adaptation, Musculoskeletal Disorders, Reliability, Validity
Medical subject headings
Musculoskeletal Diseases

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Urdu version of Nordic Musculoskeletal Questionnaire (E-NMQ) for Urdu-Speaking Populations

    Urdu version of Nordic Musculoskeletal Questionnaire (E-NMQ) for Urdu-Speaking Populations

    Measured: 6 weeks

  2. Modified Oswestry Disability Index

    As a comparator

    Measured: 6 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted4 Jun 2026
  2. Study start1 Aug 2026
  3. Primary completion10 Oct 2026 (estimated)
  4. Study completion1 Nov 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Ecologic or community
Time perspective
Prospective
Enrolment
110 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07626619
Sponsor's protocol ID
REC/RCR&AHS/25/0119
Status last verified
Sep 2026
First submitted
1 Jun 2026
Last updated
24 Sep 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Crawford JO, Berkovic D, Erwin J, Copsey SM, Davis A, Giagloglou E, Yazdani A, Hartvigsen J, Graveling R, Woolf A. Musculoskeletal health in the workplace. Best Pract Res Clin Rheumatol. 2020 Oct;34(5):101558. doi: 10.1016/j.berh.2020.101558. Epub 2020 Jul 14.

    PubMed 32680769

  • El-Tallawy SN, Nalamasu R, Salem GI, LeQuang JAK, Pergolizzi JV, Christo PJ. Management of Musculoskeletal Pain: An Update with Emphasis on Chronic Musculoskeletal Pain. Pain Ther. 2021 Jun;10(1):181-209. doi: 10.1007/s40122-021-00235-2. Epub 2021 Feb 11.

    PubMed 33575952

  • Horn CG, Jensen K, Hartvigsen J, Wekre LL, Skou ST, Folkestad L. Evaluation of the Nordic Musculoskeletal Questionnaire for Measuring Prevalence and the Consequence of Pain in a Danish Adult OI Population: A Pilot Study. Calcif Tissue Int. 2024 Oct;115(4):405-412. doi: 10.1007/s00223-024-01262-9. Epub 2024 Jul 27.

    PubMed 39066925

  • Kahraman T, Genc A, Goz E. The Nordic Musculoskeletal Questionnaire: cross-cultural adaptation into Turkish assessing its psychometric properties. Disabil Rehabil. 2016 Oct;38(21):2153-60. doi: 10.3109/09638288.2015.1114034. Epub 2016 Jan 4.

    PubMed 26726840

Questions about this trial

What is this clinical trial studying?

An observational study of Musculoskeletal Diseases, run by Riphah International University at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 24 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Imran Amjad, PhD (03324390125, Imran.amjad@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Urdu version of Nordic Musculoskeletal Questionnaire (E-NMQ) for Urdu-Speaking Populations (time frame: 6 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07626619, which also lists 4 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Sep 2026; AzTrials last refreshed its copy on 7 Nov 2026.

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