Clinical trials: Multimorbidity
Multimorbidity, Healthy
Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity
The accumulation of senescent cells with age is a central mechanism that contributes to the development of chronic diseases, primarily by driving systemic chronic inflammation.
- Trial name
- Fisetin HIGH (NCT06431932)
- Testing
- Fisetin
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ove Andersen
Multimorbidity, Knee Arthrosis
Interprofessional Preoperative Geriatric Assessment for Older Arthroplasty Patients With Multimorbidity
The objective of this randomized control trial is to investigate effects and cost effectiveness of interprofessional preoperative assessment among older knee or hip arthroplasty patients.
- Conditions
- Multimorbidity, Knee Arthrosis, Hip Arthrosis
- Trial name
- IPPGA-RCT (NCT04001699)
- Testing
- Preoperative geriatric assessment
- Where
- Finland
- Volunteers
- 157 people
- Sponsor
- University of Eastern Finland
Cardiometabolic Diseases, Multimorbidity
Health Chat for Empowerment-based Lifestyle Planning for Cardiometabolic Multimorbidity
The goal of this study is to: 1. assess the feasibility, acceptability, and the preliminary effects of the health chat for empowerment-based lifestyle planning for CMM (HcELP_CMM); 2.
- Trial name
- HcELP_CMM (NCT07158697)
- Testing
- HcELP_CMM, Usual Care
- Where
- 3 sites in China
- Volunteers
- 232 people
- Sponsor
- The University of Hong Kong
Multimorbidity
Navigation for Elderly People With Multiple Morbidity After Hospital Discharge.
This research aims to create and test a tracking (navigation) model to assist in providing care guidance to elderly people (60 years or older) who have two or more chronic diseases at the same time (multimorbidity) immediately…
- Trial name
- NAVIM (NCT07546006)
- Testing
- Navigation for elderly people after hospital discharge., Routine care.
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Homelessness, Health Promotion
Pilot Feasibility Trial of HEALthy Beginnings for Middle-Aged, and Older Homeless Women
This is a mixed methods pilot feasibility trial of HEALthy Beginnings, an innovative, nurse-driven intervention. Middle-aged and older, homeless women (MAO-HW) will participate in the HEALthy Beginnings intervention and select…
- Conditions
- Homelessness, Health Promotion, Chronic Disease Self-care, Multimorbidity
- Trial name
- HB (NCT06743685)
- Testing
- HEALthy Beginnings
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, Los Angeles
Multimorbidity
The Impact of Nurse Practitioner-Led Multidisciplinary Team Intervention on the Implementation of Guideline-Directed Medical Therapy and Clinical Outcomes in Adults With Multimorbidity
The goal of this clinical trial is to evaluate whether a nurse practitioner-led multidisciplinary team (NP-led MDT) intervention can improve the use of guideline-directed medical therapy (GDMT) and short-term clinical outcomes in…
- Trial name
- NCT07138183
- Testing
- NP-led MDT, Usual Care
- Where
- Taiwan
- Volunteers
- 178 people
- Sponsor
- National Taiwan University Hospital
Chronic Respiratory Diseases, Cardiovascular and Cerebrovascular Diseases
Chinese Population Health and Multimorbidity Study
The Chinese Population Health and Multimorbidity Study (CPHMS; initially named China Pulmonary Health Study, CPHS) was a large-scale epidemiological survey designed to investigate the pulmonary health of Chinese adults aged 20…
- Conditions
- Chronic Respiratory Diseases, Cardiovascular and Cerebrovascular Diseases, Malignant Tumors, Endocrine and Metabolic Diseases
- Trial name
- CPHMS (NCT07026370)
- Where
- China
- Volunteers
- 50,991 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Complex Patient, Multimorbidity
Pursuing the Triple Aim in Hotspotters: Identification and Integrated Care
Hotspotters are patients with complex care needs, defined by problems in multiple life domains and high acute care use. These patients often receive mismatched care, resulting in overuse of care and increased healthcare costs.
- Conditions
- Complex Patient, Multimorbidity, Psychosocial Problem, Chronic Disease
- Trial name
- NCT05878054
- Testing
- Proactive, integrated and personalised care
- Where
- Netherlands
- Volunteers
- 41 people
- Sponsor
- Leiden University Medical Center
Multimorbidity, Physical Deconditioning
Multicomponent Telerehabilitation to Engage Veterans in Effective Self-Management of Complex Health Conditions
Medically complex older Veterans are at greater risk for progressive declines in physical function, lower quality of life, and increasing care needs.
- Trial name
- NCT06288438
- Testing
- Motivational Interviewing Techniques, Physical Therapy Interventions, Education
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- VA Office of Research and Development
Multimorbidity
Enhanced Care for Patients With Complex Multimorbidity in Primary Care
Introduction Patients living with a chronic disease often have more than one chronic condition, which is referred to as multimorbidity.
- Trial name
- MM600-DK (NCT05676541)
- Testing
- Complex intervention to enhance care for patients with multimorbidity in general practice consisting of an extended overview consultation and supporting elements
- Where
- Denmark
- Volunteers
- 117,000 people
- Sponsor
- University of Copenhagen
Kidney Disease, Kidney Failure
Older Kidney Patient Optimisation Pretransplant
The goal of this clinical trial is to learn if a kidney transplant-specific comprehensive geriatric assessment (KT-CGA) can improve the way older adults are assessed for kidney transplantation.
- Conditions
- Kidney Disease, Kidney Failure, Frailty, Cognitive Impairment
- Trial name
- OK-POP (NCT07419945)
- Testing
- Kidney transplant-specific comprehensive geriatric assessment
- Volunteers
- 50 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Multimorbidity, Older Adults (65 Years and Older)
Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT
The goal of this clinical trial is to learn if I-CONNECT (Integrated Care for Older Adults with Major Depression and Physical Multimorbidity) can improve the health and well-being of older adults with depression or bipolar…
- Conditions
- Multimorbidity, Older Adults (65 Years and Older), Mood Disorders, Depression - Major Depressive Disorder
- Trial name
- I-CONNECT (NCT07211750)
- Testing
- integrated care intervention tailored to the needs of older adults leaving at home with mood disorders and multimorbidity in Leuven
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- KU Leuven
Multimorbidity, Comorbidity
A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students
Junior high school students are in a critical period of physical and mental development, currently facing two major health challenges: first, persistently high rates of myopia with a noticeable trend toward younger onset; second…
- Conditions
- Multimorbidity, Comorbidity, Common Diseases in Children and Adolescents, Myopia
- Trial name
- NCT07237698
- Testing
- The intervention group participated in specialized physical education courses.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Wu
Multimorbidity
High-Risk Veteran Initiative
Veterans at high-risk for hospitalization, including those with complex care needs, represent a large population of VHA patients who often do not receive evidence-based primary care practices that would help them avoid the…
- Trial name
- RIVET (NCT05050643)
- Testing
- EBQI-IC, EBQI-LC
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Multimorbidity
Effectiveness of a Patient-oriented Discharge Summary
The discharge preparation is a difficult time to provide teaching, as older patients and their caregivers are often overwhelmed by a substantial amount of information and stressed about leaving hospital.
- Trial name
- PODS (NCT06123546)
- Testing
- Patient oriented discharge summary
- Where
- Switzerland
- Volunteers
- 111 people
- Sponsor
- University of Lausanne
Kidney Transplant, Cardiovascular (CV) Risk
Multimorbidity and Cardiovascular Risk Factors After Renal Transplant
Who can participate? Any adults over the age of 18 who have received a kidney transplant at the research centre are eligible for recruitment within the first month after transplant What does the study involve? The study involves…
- Conditions
- Kidney Transplant, Cardiovascular (CV) Risk, Multimorbidity
- Trial name
- MCaRT (NCT07205692)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Exercise, Sedentary Behavior
Association of a Digital Signature of Physical Activity and Sedentary Lifestyle With the Development of Multimorbidities in Chronic Diseases (eMOB)
Physical activity (PA) and sedentary lifestyle are determinants in the development of chronic diseases and associated quality of life alterations.
- Conditions
- Exercise, Sedentary Behavior, Non Communicable Diseases, Comorbidities and Coexisting Conditions
- Trial name
- eMOB (NCT05578495)
- Testing
- Accelerometer data
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Clermont-Ferrand
Multimorbidity, Hypertension
Development and Validation of a Comprehensive Management Service Package for Older Adults With Multimorbidity
This study aims to test a new comprehensive management service package for older adults with two or more chronic conditions (multimorbidity).
- Conditions
- Multimorbidity, Hypertension, Diabetes Mellitus, Coronary Artery Disease
- Trial name
- COMPASS (NCT07151430)
- Testing
- Service Package Group
- Volunteers
- 358 people
- Sponsor
- Xuanwu Hospital, Beijing
Elderly, Multimorbidity
Telemedicine and Nursing Home
Telemedicine-based care provides remote health and social care to maintain people's autonomy and increase their quality of life.
- Trial name
- GERONTACCESS (NCT02816177)
- Testing
- Telemedicine, Usual Care
- Where
- France
- Volunteers
- 428 people
- Sponsor
- University Hospital, Limoges
Multimorbidity, Heart Failure
Effectiveness of a Multimodal Intervention With Simulation for Learning Home Health Nursing Care of Patients With Multimorbidity and Heart Failure
The goal of this clinical trial is to evaluate the efficacy of a multimodal intervention with high-fidelity simulations on home health nursing in improving the care of multipathological patients with heart failure in nursing…
- Trial name
- NCT06855719
- Testing
- Training in high-fidelity simulation and knowledge of care protocols in patients with multimorbidity and heart failure
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Cadiz