Clinical trials: Mucositis Oral
Oral Mucositis, Effects of Chemotherapy
Laser Therapy Prevents Mucositis Oral in Chemotherapy for Bone Marrow Transplantation?
Setting: Oral mucositis is a very common complication of cancer treatment, accounting, often at increased risk for infections and even the interruption of treatment, interfering with the prognosis of the disease.
- Conditions
- Oral Mucositis, Effects of Chemotherapy, Malignant Neoplasm of Bone Marrow
- Trial name
- lasertherapy (NCT02020928)
- Testing
- Low level laser therapy
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Recurrent Aphthous Stomatitis
Effect of Zinc Oxide Ointment on Recurrent Aphthous Stomatitis
This randomized placebo-controlled trial evaluated the effectiveness of zinc oxide ointment in the treatment of recurrent aphthous stomatitis (RAS).
- Trial name
- ZO-RAS (NCT07565181)
- Testing
- zinc oxide, Placabo
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Faculty of Dental Medicine for Girls
Steven-Johnson Syndrome, Toxic Epidermal Necrolysis
Severe Cutaneous Adverse Reactions in Thailand
The multicenter registry of patients with severe cutaneous adverse reactions among tertiary medical institutes in Thailand to study clinical characteristics, etiologies, therapeutic outcomes, quality of life, and the values of in…
- Conditions
- Steven-Johnson Syndrome, Toxic Epidermal Necrolysis, Drug Reaction With Eosinophilia and Systemic Symptoms, Acute Generalized Exanthematous Pustulosis
- Trial name
- ThaiSCAR (NCT02574988)
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Chulalongkorn University
Peri-implant Mucositis
Efficacy of a Xanthan-based Chlorhexidine Gel in the Treatment of Peri-implant Mucositis
The peri-implant mucositis is an inflammatory and reversible lesion that surrounds the peri-implant mucosa without loss of supporting bone, clinically characterized by bleeding on gentle probing.
- Trial name
- NCT07047261
- Testing
- Adjunctive use of Xanthan-Chlorexidine based gel
- Where
- Italy
- Volunteers
- 182 people
- Sponsor
- University of Turin, Italy
Severe Acute Mucositis, Head and Neck Cancer
Randomised Study of Mucositis Prevention After Radiochemotherapy Treatment for Head and Neck Cancer
This randomised, double-blind study will compare an oral immunomodulatory solution to a placebo for the prevention of acute severe mucositis in head and neck cancer patients treated surgically and concomitantly with…
- Trial name
- IMPATOX (NCT01149642)
- Testing
- Oral Impact
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Mucositis, Head and Neck Cancer
Analgesic Effects of Topical Ketamine Mouthwash in Patients Receiving Chemoradiation or Radiotherapy for Head & Neck Cancer
The primary objective is to determine the reduction in pain score by ketamine mouthwash compared to placebo in head and neck cancer patients with refractory mucositis.
- Trial name
- NCT01653327
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Oral Mucositis (Ulcerative) Due to Radiation
Melatonin for Prevention of Radiation Induced Oral Mucositis
The main aim of this study was to evaluate the effectiveness of melatonin in prevention of radiation induced oral mucositis clinically and biochemically.
- Trial name
- NCT03833570
- Testing
- Rapid Release Capsules Melatonin, 10 mg, Miconaz oral gel, BBC oral spray
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman
Oral Herpes Simplex
Safety and Efficacy Study of a New Treatment for Recurrent Symptoms of Oral Herpes Virus Infection
The purpose of this study is to determine if a new treatment is effective for the treatment of recurrent symptomatic oral herpes virus infections.
- Trial name
- NCT01308424
- Testing
- BTL TML HSV
- Where
- 4 sites in United States
- Volunteers
- 171 people
- Sponsor
- Beech Tree Labs, Inc.
Aphthous Ulcer
The Efficacy of Nigella Sativa Oil Mouth Rinse in the Management of Recurrent Minor Aphthous Ulcer
This research aims to investigate the effectiveness of Nigella Sativa Oil Mouth Rinse application both clinically and biochemically as a suitable affordable treatment modality for Management of Recurrent Minor Aphthous Ulcer
- Trial name
- NCT06013202
- Testing
- Nigella Sativa Oil Mouth Rinse, isotonic (normal saline) with concentration 0.90% of sodium chloride (NaCl)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nada Sherif
Cancer
Vitamin E to Prevent Mucositis in Children With Cancer
The primary objective is to determine whether in children undergoing doxorubicin-containing chemotherapy, if topical vitamin E, when compared to placebo, decreases an objective measurement of oral mucositis.
- Trial name
- NCT00311116
- Testing
- Vitamin E
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- The Hospital for Sick Children
Swallowing-induced Pain
Doxepin Solution for Alleviation of Stubborn Breakthrough Pain Induced by Swallowing in Patients Receiving Radiotherapy for Nasopharyngeal Carcinoma
The goal of this clinical trial is to explore the effectiveness and adverse reactions of doxepin solution spray for alleviation of stubborn breakthrough pain induced by swallowing in patients receiving radiotherapy for…
- Trial name
- NCT06017895
- Testing
- doxepin solution
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma
SNP-Based Prediction of Oral Mucositis Risk in Patients Receiving Hematopoietic Stem Cell Transplants (HSCT)
The goal of this study is to gain new knowledge about genetic risk factors thta may affect the development of mucositis, the chemotherapy-induced sores in the mouth and esophagus following HSCT.
- Conditions
- Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma, Multiple Myeloma
- Trial name
- NCT01402687
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- Dana-Farber Cancer Institute
Head and Neck Cancer
A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer
The purpose of this study is to evaluate the efficacy and safety of palifermin (recombinant human keratinocyte growth factor, rHuKGF) in reducing the incidence of severe oral mucositis in subjects with locally advanced head and…
- Trial name
- NCT00131638
- Testing
- Palifermin
- Volunteers
- 241 people
- Sponsor
- Amgen
Stomatitis
An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.
This is a multicenter, open-label, single-arm study of prophylaxis for Dato-DXd-related stomatitis in eligible patients with metastatic or inoperable locally recurrent breast cancer or locally advanced or metastatic Epidermal…
- Trial name
- TROPION-SWISH (NCT07357597)
- Testing
- Dexamethasone mouthwash, Datopotamab Deruxtecan (Dato-DXd)
- Where
- 40 sites in United States
- Volunteers
- 100 people
- Sponsor
- AstraZeneca
Denture Stomatitis
Effect of Aqueous Extract of Garlic and Nystatin Mouthwash in Denture Stomatitis
The aim of the present study was to compare the effect of aqueous extract of garlic with nystatin mouthwash in denture stomatitis.
- Trial name
- NCT01198223
- Testing
- garlic , nystatin
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Qazvin University Of Medical Sciences
Oral Ulcer
Basil Extract (Ocimum Basilicum) in the Management of Recurrent Aphthous Stomatitis
A randomized double-blind placebo controlled trial will be carried out on 20 patients complaining from aphthus ulcer and 10 patient healthy control 10 patients treated with mucoadhesive gel containing 2% of basil extract 4 times…
- Trial name
- RCT (NCT04710888)
- Testing
- use of basil extract gel in treatment of aphthus ulcer, no treatment
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University