Clinical trials: Motor Impairment
Alzheimer Disease, Early Onset, MCI
The Interactive Physical and Cognitive Exercise System
This study is intended to clarify the benefits to brain health and thinking processes that result from different forms of exercise.
- Conditions
- Alzheimer Disease, Early Onset, MCI, Aging, Mild Cognitive Impairment
- Trial name
- iPACES™ (NCT03069391)
- Testing
- physical exercise alone (PES) first, cognitive exercise alone (iCE) first, interactive Physical and Cognitive Exercise (iPACES™)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Union College, New York
Impaired Thermoregulation
Effects of Pre-Exercise Nutrition Strategies on Body Temperature and Thermoregulatory Responses
Carbohydrate ingestion, in particular fructose, has been shown in a handful of previous studies to elicit a thermic effect and increase core body temperature after ingestion.
- Trial name
- NCT02814188
- Testing
- Carbohydrate Beverage
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Cerebral Palsy
Investigation of Relations Between Edinburgh Visual Gait Score and Selective Motor Control for Children With CP
Children with Cerebral Palsy have generally limited selective motor control which affects their ability to complete functional tasks Selective Motor Control has been shown to correlate with specific characteristics of gait…
- Trial name
- NCT04686630
- Testing
- Video based observational gait analysis and SCALE Test
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Yeditepe University
Aging, Exercise
Assessing Cognitive and Health Improvements in the Elderly Via Exercise (ACHIEVE) - Study.
In Colombia, a demographic transition is occurring that is reflected in an inverted population pyramid, with an increase in the proportion of older adults due to a better quality of life, as well as a decrease in the young…
- Trial name
- NCT06052644
- Testing
- Exercise Dose-Response
- Where
- Colombia
- Volunteers
- 118 people
- Sponsor
- University of Jaén
Stroke Rehabilitation
Effectiveness of Transcranial Magnetic Stimulation in Subacute Stroke Patients With Severe Upper Limb Paresis
There has been A-level evidence for the effectiveness of inhibitory rTMS of the contralesional M1 hand region in stroke patients in the acute stage. However, it has been reported to be ineffective in the chronic stage.
- Trial name
- NCT05505201
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 6 people
- Sponsor
- Izmir Katip Celebi University
Multiple Sclerosis, Relapsing-Remitting
Targeting Subclinical Motor and Cognitive Impairment in Patients With Early Onset Multiple Sclerosis
Our project proposal is based on an individualized rehabilitation approach in patients with early stage relapsing remission (RR) MS.
- Trial name
- RELIABLE (NCT06303024)
- Testing
- personalized combined physical and cognitive intervention
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Mild Cognitive Impairment, Accidental Falls
A Study of Dual-task Exercise Training to Prevent Falls Among Older Adults With Mild Cognitive Impairment
To determine the efficacy of a dual-task tai ji quan training therapy in reducing the incidence of falls in older adults with mild cognitive impairment.
- Conditions
- Mild Cognitive Impairment, Accidental Falls, Aging
- Trial name
- NCT05725668
- Testing
- dual-task tai ji quan, standard tai ji quan, stretching
- Where
- United States
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Patients Treated for Cancer
Cancer Related Cognitive Impairment
Various recent scientific data testify to the cognitive deficiencies of cancer patients, called Cancer-Related Cognitive Impairments (CRCI) (Noal, Daireaux \& Joly, 2010).
- Trial name
- APACO (NCT03949322)
- Testing
- Adapted Physical Activity Program
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Institut Cancerologie de l'Ouest
Motor Recovery
BreEStim for Post-Stroke Motor Recovery
The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with…
- Trial name
- NCT04750551
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke, Neurological Diseases or Conditions
Development and Efficacy of a Novel, Cost-Effective Gait Training Device Utilized at Home for Stroke Survivors
This pilot, parallel-group randomized controlled trial will evaluate the feasibility, safety, usability, and preliminary efficacy of the Rise\&Walk InHome (RWH), a novel robotic gait training device designed for home use after…
- Conditions
- Stroke, Neurological Diseases or Conditions, Hemiparesis;Poststroke/CVA, Gait Disorders, Neurologic
- Trial name
- NCT07250425
- Testing
- Rise&Walk InHome by Healing Innovations
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Healing Innovations
Mild Cognitive Impairment, Dementia
Remote Game-based Exercise Program for Cognitive and Motor Function Improvement
As our population ages, more older adults face motor-cognitive declines, increasing their risk of falls and fear of falling. Exercise is an effective way to maintain cognitive function, as supported by recent studies.
- Conditions
- Mild Cognitive Impairment, Dementia, Cognitive Impairment, Memory Loss
- Trial name
- NCT05235113
- Testing
- Tele-Exergame Platform, No Tele-Exergame Platform
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- University of California, Los Angeles
Coginitive Dysfunction
The Effects, Usability, Satisfaction, Barriers, and Benefits of a Remote, Multidomain Website-based Intervention to Prevent Cognitive Decline in Older Adults
Mexico exhibits a high prevalence of dementia, exceeding 8%, and it is estimated that by 2050 around 3.5 million older adults will be living with this condition.
- Trial name
- MeMoHealthCogR (NCT07668440)
- Testing
- Multi-domain intervention: Physical activity, cognitive training, and educational program through a website
- Where
- Mexico
- Volunteers
- 71 people
- Sponsor
- Instituto Mexicano del Seguro Social
Hearing Impaired
Brain and Cognitive Changes After Reasoning or Physical Training in Cognitively Normal Seniors
Seniors 65 years of age and older represent one of the fastest growing segments of society with the population doubling within the next 25 years with dramatic rates of mental decline, costing society billions of dollars each…
- Trial name
- NCT00977418
- Testing
- SMART- Strategic Memory and Reasoning Training, Physical Exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Childhood Cancer, Cognitive Impairment
Cognitive and Motor Training in Pediatric Posterior Fossa Tumor Survivors
The purpose of this study is to create a rehabilitation program for children who survived posterior fossa tumors using the latest technology.
- Conditions
- Childhood Cancer, Cognitive Impairment, Motor Skills Disorders, Posterior Fossa Tumor
- Trial name
- NCT03951246
- Testing
- Cognitive and Motor Training
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Cognitive Decline, Cognitive Impairment
Effects of Cognitive Intervention on Cognition, Mobility and Brain Electrocortical Activity
Within this project the investigators tested the effectiveness of 2-month of computerized cognitive training (CCT) on CogniFit online platform on 77 older adults, which were randomly divided into intervention and control group.
- Conditions
- Cognitive Decline, Cognitive Impairment, Aging, Motor Coordination or Function
- Trial name
- GIBKOP (NCT03860441)
- Testing
- Computerized cognitive training
- Where
- Slovenia
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Science and Research Centre Koper
Stroke
Motor Recovery of the Severely Impaired Paretic Upper Limb After Mirror Therapy in Sub-acute Stroke
Our study aims at investigating the effect of intensive mirror therapy on the motor recovery of severely impaired paretic arm at subacute stroke.
- Trial name
- NCT02942875
- Testing
- mirror therapy, control therapy
- Where
- Hong Kong
- Volunteers
- 35 people
- Sponsor
- The Hong Kong Polytechnic University
Mild Cognitive Impairment
Multi-component Exercise on Mild Cognitive Impairment In Elderly Population
Participants will be randomized to exercise intervention and control groups, for 6 weeks. The participants will be examined for following test Mini mental state examination, Trail making test A and B, MOCA.
- Trial name
- NCT03938051
- Testing
- Experimental group, Control group
- Where
- Pakistan
- Volunteers
- 51 people
- Sponsor
- Riphah International University
Aging, Cognitive Decline
Augmented Reality Treadmill Walking for Cognitive and Physical Health in Older Adults
This study evaluated the feasibility and health effects of using augmented reality (AR) treadmill walking in older adults. Sixty community-dwelling adults aged 65 to 80 years were randomly assigned to either an AR treadmill group…
- Conditions
- Aging, Cognitive Decline, Sarcopenia, Mobility Limitation
- Trial name
- ART-Walk (NCT07074613)
- Testing
- Traditional Treadmill Walking, JOHNSON 8.1T treadmill with Passport AR system
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan College of Performing Arts
Adult Children
Investigation of Physical Impairments in Young Adults
Physical inactivity is widespread among young adults due to different disasters like the COVID-19 and earthquakes. On the other hand, it is unknown how physical activity level affects cough strength and balance in young adults.
- Trial name
- NCT06561776
- Testing
- Physical Evaluations of individuals
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Izmir Democracy University
Stroke
Physical Performance and Cognitive Functions in Patients With Chronic Stroke
This study aims to investigate the impact of cognitive impairment on upper extremity physical performance, cognitive skills, and functional independence in individuals with chronic stroke.
- Trial name
- NCT07887776
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Kutahya Health Sciences University