Clinical trials: Motor Cortex; Lesion
Stroke, Motor Cortex; Lesion
Imaging Laterality in Chronic Stroke Patients
In healthy individuals, unimanual movement (with either the left or right hand) is associated with activity in a network of predominantly contralateral brain regions, including the primary motor cortex (PMC).
- Trial name
- NCT03584425
- Testing
- Rasch modified version of the Fugl-Meyer Motor assessment, Anatomical image acquisition, Functional MRI task and acquisition
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Ischemic Stroke
Study of the Therapeutic Effects of Cortical Autograft Implantation in Patients With Cerebral Ischemia
Brain lesions in the adult have dramatic consequences, because the spontaneous capacity of the brain to functionally recover is limited. Besides existing rehabilitative therapeutic approaches (e.g.
- Trial name
- AVCell (NCT04488965)
- Testing
- Autologous transplant
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Glioma, Glioma Intracranial
A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas
This study uses a cranial implant to deliver cortical stimulation that, when paired with physiotherapy, will remap the brain so that critical brain functions can be protected during brain tumor surgery.
- Conditions
- Glioma, Glioma Intracranial, Gliomas Benign, Brain Tumor
- Trial name
- NCT04745156
- Testing
- RNS System Implantation
- Volunteers
- 3 people
- Sponsor
- Medical College of Wisconsin
Focal Dystonia
Motor and Premotor Cortex Stimulation for Treatment of Secondary Focal Dystonia With Striato Palliadal Lesion : Evaluation of Safety and Effectiveness
Dystonia is a neurological movement disorder in which sustained muscle contractions cause twisting and repetitive movements or abnormal postures. This disease is very heterogeneous and can have many causes.
- Trial name
- CORDYS (NCT00505323)
- Testing
- Implantation of neurostimulators and their auxiliary components
- Volunteers
- 5 people
- Sponsor
- University Hospital, Clermont-Ferrand
Healthy
Transcranial Magnetic Stimulation to Study Imagination of Movement
This study will use transcranial magnetic stimulation (TMS) to examine the relationship between cognitive processing and motor control by determining whether a part of the brain called the premotor cortex is essential to…
- Trial name
- NCT00046215
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Brain Tumor, Brain Cancer
A Study to Measure the Effect of Brain Stimulation on Hand Strength and Function in Patients With Brain Tumors
The neurosurgical standard of care for treating a patient with a tumor invading hand primary motor cortex (M1) includes performing a craniotomy with intraoperative direct electrical stimulation (DES) mapping and to resect as much…
- Conditions
- Brain Tumor, Brain Cancer, Motor Cortex; Lesion
- Trial name
- NCT05023434
- Testing
- Intraoperative Brain Simulation - Alternate Stimulation Parameters
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Brain Lesion, Brain Tumor Adult
Handheld Dynamometer During Awake Craniotomy Pilot
The primary purpose of this study is to assess the feasibility, safety and reliability of the use of handheld dynamometry in evaluating intraoperative motor function for patients undergoing awake craniotomy for the resection of…
- Conditions
- Brain Lesion, Brain Tumor Adult, Brain Tumor
- Trial name
- NCT04742231
- Testing
- Hand-held dynamometer
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Motor Cortex; Lesion, Glioma
Accelerating Motor Recovering in Patients With SMA Syndrome After Glioma Surgery by Using nrTMS
The goal of this randomized clinical controlled trial is to learn about whether neuro-navigation repetitive transcranial magnetic stimulation (nrTMS) was useful to accelerate the recovery in patients with SMA syndrome after…
- Conditions
- Motor Cortex; Lesion, Glioma, Supplementary Motor Area Syndrome
- Trial name
- NCT05803057
- Testing
- TMS stimulation treatment
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Beijing Neurosurgical Institute
Paraplegia, Spinal, Myelomeningocele
Brain Function and White Matter Changes in Congenital, Acute and Chronic Spinal Cord Lesions
The purpose of this study is to use functional MRI (fMRI) and magnetic resonance (MR) diffusion tensor imaging (DTI) to investigate brain activation and white matter changes in patients with congenital (birth defect of the spinal…
- Trial name
- NCT01208584
- Testing
- fMRI, DTI
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland