Clinical trials: Morbidity
Pacemaker Complication, Arrhythmias, Cardiac
Association of Obesity and Cardiovascular Outcomes in Patients With Pacemaker
In this study, the investigators evaluated the association between various measures of adiposity [BMI and waist circumference (WC)] and clinical outcomes in Asian patients who underwent pacemaker insertion, using a nationwide…
- Conditions
- Pacemaker Complication, Arrhythmias, Cardiac, Obesity, Cardiovascular Morbidity
- Trial name
- Paradox (NCT05645978)
- Testing
- Pacemaker insertion
- Where
- South Korea
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
Preventive Medicine
Clinical Trial of Anaferon for Children Efficacy in Prevention of Influenza and Other ARVI
The objective of this study is to obtain additional data on the efficacy and safety of 12-week course of therapy with Anaferon for children for prevention of influenza and other acute respiratory viral infections in children…
- Trial name
- NCT03301155
- Testing
- Anaferon for children
- Where
- 33 sites in Russia, Uzbekistan
- Volunteers
- 1,036 people, healthy volunteers welcome
- Sponsor
- Materia Medica Holding
Diabetes Type 2, Renal Failure
A Study of the Usefulness & Usability of a Healthcare IT System for Managing Multi-morbidity and Poly-pharmacy
To assess the acceptability of a personalised ICT tool that facilitates coordinated care planning, treatment optimisation and patient self-management for patients with multiple long term conditions and their team of health…
- Conditions
- Diabetes Type 2, Renal Failure, Heart Failure, Depression
- Trial name
- C3-Cloud (NCT03834207)
- Testing
- Use of the C3-Cloud IT system
- Where
- 3 sites in Spain, Sweden and 1 more
- Volunteers
- 672 people
- Sponsor
- Dr Christopher Marguerie
Mastectomy; Lymphedema, Chronic Pain
Erector Spinae Block Versus Paravertebral Block on Chronic Pain After Mastectomy
The goal of this clinical trial is to learn if the erector spinae block can reduce the incidence of chronic pain compared to the paravertebral block in adult patients undergoing total mastectomy.
- Conditions
- Mastectomy; Lymphedema, Chronic Pain, Regional Anesthesia Morbidity, Opioid Use
- Trial name
- NCT07561411
- Testing
- Paravertebral block, Erector Spinae block
- Where
- Lebanon
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Hepatectomy, Elective Hepatectomy
Interest of PReOPerative Immunonutrition in Liver Surgery for Cancer
To study the efficacy of preoperative immunonutrition in reducing postoperative morbidity after liver resection for cancer.
- Conditions
- Hepatectomy, Elective Hepatectomy, Malignant Tumors
- Trial name
- PROPILS (NCT02041871)
- Testing
- Oral immunonutrition
- Where
- France
- Volunteers
- 399 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neonatal Morbidity and Mortality, Intrauterine Growth Disorders (IUGR and Macrosomia)
Analysis on the Health of Newborns in Three Hospitals, 2008-2024
The objective of this observational study is to analyze the factors associated with neonatal morbidity and mortality in three hospitals in Quito, Ecuador, from January 2008 to June 2024.
- Conditions
- Neonatal Morbidity and Mortality, Intrauterine Growth Disorders (IUGR and Macrosomia), Prematurity Complications, Neonatal Infections
- Trial name
- NCT06758622
- Where
- Ecuador
- Volunteers
- 40,000 people
- Sponsor
- HOSPITAL GINECO OBSTETRICO ISIDRO AYORA
Cardiovascular Diseases, Lidocaine Causing Adverse Effects in Therapeutic Use
Evaluation of the Effect of 10% Lidocaine Spray Undergoing Coronary Artery Bypass Graft Operation
In patients undergoing coronary bypass surgery; 10% topical lidocaine administered endotracheally before intubation is to investigate the effect of hemodynamic response and EKG paramater after intubation.
- Conditions
- Cardiovascular Diseases, Lidocaine Causing Adverse Effects in Therapeutic Use, Tracheal Intubation Morbidity
- Trial name
- ELCABG (NCT03304431)
- Testing
- Orotracheal Lidocaine Oral Spray application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Acute Lymphoblastic Leukemia
Neurologic Morbidity and Disability in Acute Lymphoblastic Leukemia Survivors
Treatment of acute lymphoblastic leukemia achieves high cure rate, but is potentially neurotoxic. Long-term neurologic morbidity in survivors and its effect on function are inadequately studied.
- Trial name
- NCT00664131
- Testing
- Neurological Examination/Questionnaires
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- St. Jude Children's Research Hospital
Shoulder Symptoms After Lymph Node Dissection
Pulsed Electromagnetic Fields (PEMF) and Post-Axillary Surgery Morbidity
The most important prognostic indicator for the breast cancer patient is the axillary lymph node status. With the introduction of the sentinel lymph node biopsy, many women were spared the morbidity of a full axillary lymph node…
- Trial name
- NCT01255631
- Testing
- PEMF Device
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Columbia University
Regional Anesthesia Morbidity
Dexmedetomidine in IVRA
A prospective randomized controlled double-blinded study will be conducted on 90 patients assigned randomly into three equal groups,
- Trial name
- NCT05123170
- Testing
- Dexmedetomidine Injectable Solution [Dexdomitor], Lidocaine IV
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Hyperglycemia, Leukemia
Intensive Glycemic Control on Infectious Morbidity In Patients With Acute Leukemia
RATIONALE: Controlling blood sugar levels may be effective in preventing infections in patients receiving chemotherapy for acute myeloid leukemia or acute lymphoblastic leukemia.
- Trial name
- NCT00943709
- Testing
- insulin glargine recombinant, therapeutic insulin
- Where
- United States
- Sponsor
- University of Medicine and Dentistry of New Jersey
Obesity, Morbid, Stem Cells
Effect of Weight Loss Surgery on Stem Cells.
Obesity and diabetes are linked to increased risk for health problems such as heart attack, stroke, and death. At the cellular level, obesity and diabetes increase levels of harmful inflammatory cells (M1 macrophages) and…
- Conditions
- Obesity, Morbid, Stem Cells, Cardiovascular Morbidity
- Trial name
- NCT04132531
- Testing
- Bariatric (weight loss) surgery
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Helicobacter Pylori Resistance
Helicobacter Pylori Resistance
The main goal of the study was to characterize the morbidity, immunological, microbiolical and clinical phenotypes of patients with treated- resistance to Helicobacter pylori (HP) infection, and the effect of triple therapy…
- Trial name
- CRIHEP (NCT05019586)
- Testing
- levofloxacin, amoxicillin, clarithromycin
- Volunteers
- 185 people
- Sponsor
- University Hospital of North Norway
Respiratory Depression, Anesthesia Morbidity
Effect of Interscalene Block on Ventilatory Function
Interscalene block with local anesthetic impairs ventilation (unilateral diaphragmatic dysfunction). Single injection of local anesthetic induced transitory dysfunction (< 24h).
- Conditions
- Respiratory Depression, Anesthesia Morbidity, Block
- Trial name
- KTBIS (NCT01740453)
- Testing
- ropivacaine 2 mg/ml
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Pierre and Marie Curie University
PTSD, Post ICU Syndrome
Intensive Care Unit (ICU) Diary Project
Psychological morbidity in both patients and family members related to the intensive care unit (ICU) experience is an often overlooked, and potentially persistent, healthcare problem recognized by the Society of Critical Care…
- Trial name
- NCT04305353
- Testing
- Diary (blank journal) plus PTSD psycho-education, PTSD psycho-education alone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Tulane University School of Medicine
Airway Morbidity
Comparative Evaluation of Three Airway Maneuvers in the Unconscious Apneic Person
One-handed E-C clamp mask holding technique, two-handed mask ventilation with jaw thrust, and two-handed mask ventilation with triple airway maneuver are three common airway management maneuvers.
- Trial name
- NCT02104453
- Testing
- airway maneuver
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Congestive Heart Failure
Candesartan Cilexetil in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Added)
A study to evaluate the effect of Atacand on patients with heart failure with depressed left ventricular function
- Trial name
- NCT00634309
- Testing
- Candesartan
- Volunteers
- 597 people
- Sponsor
- AstraZeneca
HIV-associated Co-morbidities
Vitamin D Supplements for HIV-positive Patients on cART
The ability of vitamin D to modulate the immune system and strengthen bones may mitigate the adverse medication consequences of HIV/AIDS, but little is known about either the health benefits of vitamin D supplements, or about the…
- Trial name
- NCT01295034
- Testing
- conventional vitamin D treatment, tiered/titrated vitamin D dosing
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Andrea Branch
Establish the Efficacy Between the Four Schemes in Terms of the Aggressiveness of the Tumors According to the Gleason Classification, Establish the Efficacy Between the Four Schemes in Terms of Morbidity Associated With the Technique
Impact of Magnetic Resonance and Biomarkers for Screening for Prostate Cancer. Cost-effectiveness Analysis
Objectives: To establish if there are differences between an ultrasound-guided transrectal prostate biopsy (BPTE) and a transperineal prostatic biopsy (BPTP) with and without a multiparametric Magnetic Resonance (RMmp) in…
- Conditions
- Establish the Efficacy Between the Four Schemes in Terms of the Aggressiveness of the Tumors According to the Gleason Classification, Establish the Efficacy Between the Four Schemes in Terms of Morbidity Associated With the Technique, Establish the Efficacy Between the Four Schemes in Terms of the Patient's Subjective Perception Regarding Pain and Quality of Life, Establish the Association of the Tumor Biomarker in the Early Detection and Aggressiveness of Tumors
- Trial name
- RMPBX201801 (NCT04283032)
- Testing
- Multiparametric magnetic resonance
- Where
- Spain
- Volunteers
- 628 people
- Sponsor
- InvestigatorUrologyIBSAL
Intubation Complication, Anaesthesia
Laryngeal Morbidity After Endotracheal Intubation - Endoflex-tube Versus Use of Stylet
This study is aimed at reducing the risk of hoarseness and damage to the vocal cords following general anaesthesia. Conventional endotracheal intubation with use of a stylet will be compared with the Endoflex tube.
- Trial name
- NCT00953433
- Testing
- Endoflex tube, Polyvinyl chloride endotracheal tube with a stylet
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet