Clinical trials: Mononeuropathies
Carpal Tunnel Syndrome
Ultrasound-Guided 5% Dextrose Injection for Carpal Tunnel Syndrome
This study was a prospective randomized double-blind clinical trial conducted at the Physical Medicine and Rehabilitation Clinic of a local research and training hospital in Turkey from October 2023 and May 2024.
- Trial name
- NCT06349265
- Testing
- Carpal Tunnel Hydrodissection with %5 dextrose in water injection
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Kastamonu University
Carpal Tunnel Syndrome
Carpal Tunnel Syndrome Release Using PSU Retractor
The investigators study aims to evaluate both efficacy and safety of carpal tunnel release using limited incision with the PSU retractor compared to standard incision.
- Trial name
- NCT01017471
- Testing
- Limited incision using PSU retractor
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Prince of Songkla University
Carpal Tunnel Syndrome (CTS)
Comparative Effects of Sensory Re-education and Neural Mobilization in CTS Patients
The aim of study is to compare the effects of sensory re-education and neural mobilization in CTS patients.
- Trial name
- NCT06686212
- Testing
- Sensory re-education+ strengthening exercises+ kinesio taping, Neural mobilization+ Strengthening exercises+ Kinesio taping.
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Carpal Tunnel Syndrome Treatment
Effectiveness of Corticosteroid and 5% Dextrose Versus USG-guided Ozone Injections in Patients With Carpal Tunnel Syndrome: Three Blind Randomized Studies
Effectiveness of corticosteroid and 5% dextrose versus USG-guided ozone injections in patients with carpal tunnel syndrome: Three blind randomized studies
- Trial name
- NCT07002892
- Testing
- Ozon treatment, Steroid treatment, Dextrose 5%
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Yunus Burak Bayır
Foot Drop, Peripheral Nervous System Diseases
Walking Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project
The purpose of this research study is to test the utility of an ankle robot, when used during treadmill walking, in people with ankle weakness and foot drop from a peripheral nervous system injury due to neuromuscular or…
- Conditions
- Foot Drop, Peripheral Nervous System Diseases, Gait Disorders, Neurologic, Mobility Limitation
- Trial name
- NCT03556709
- Testing
- Treadmill Ankle Robot Training
- Volunteers
- 100 people
- Sponsor
- Baltimore VA Medical Center
Carpal Tunnel Syndrome
Comparison of Efficacy Between Conservative Versus Operative Management of Carpel Tunnel Syndrome
Patients presented with symptoms of numbness at night, pain, or tingling sensation in the fingers particularly at night diagnosed by consultant orthopedic surgeon on physical examination.
- Trial name
- NCT06060314
- Testing
- Conservative Approach, Surgical Approach
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Combined Military Hospital Abbottabad
Cubital Tunnel Syndrome, Electrical Stimulation
Conditioning Electrical Stimulation to Improve Outcomes in Cubital Tunnel Syndrome
Cubital tunnel syndrome is the second most common compression neuropathy. In severe cases, functional recovery, even with surgery, is often poor.
- Trial name
- NCT05395715
- Testing
- Electrical stimulation
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Multiple Sclerosis, Foot Drop
Walking With FES or AFO in People With MS With Foot Drop
This investigation consists of two parallel groups of participants who will follow the same protocol. The aim of the study is to investigate the effects of using Functional Electrical Stimulation/Ankle Foot Orthosis (AFO) or…
- Trial name
- NCT01977287
- Testing
- Functional Electrical Stimulation, Ankle Foot Orthosis
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Queen Margaret University
Carpal Tunnel Surgery, Trigger Finger Disorder
NAC-REPAIR for Post-surgical Pain
This pilot asks whether peri-operative N-acetylcysteine (NAC) improves recovery after common outpatient hand/foot-ankle surgery-specifically, does NAC reduce pain and opioid use and enhance function by modulating…
- Conditions
- Carpal Tunnel Surgery, Trigger Finger Disorder, De Quervain Syndrome, Guyon's Canal
- Trial name
- NCT07227649
- Testing
- NAC
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Arizona
Carpal Tunnel Syndrome, Exercise
Carpal Tunnel Syndrome in Pregnant Women
The purpose of our study is to evaluate the effectiveness of the home exercise program in patients who develop Carpal tunnel syndrome (CTS).
- Trial name
- NCT03718598
- Testing
- Tendon and Nerve Gliding Exercises
- Volunteers
- 33 people
- Sponsor
- Bezmialem Vakif University
Carpal Tunnel Syndrome, Pregnancy Related
Effects of High Intensity Laser on Mechanical and Physiological Findings in Pregnant Women With Carpal Tunnel Syndrome
This study will propose a novel approach to treat pregnant women with mild to moderate carpal tunnel syndrome (CTS) using the recently introduced High intensity laser therapy with its deep penetration and high-power…
- Trial name
- NCT04969393
- Testing
- High intensity laser therapy, Conventional Physical Therapy
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- October 6 University
Carpal Tunnel Syndrome, Charcot-Marie-Tooth Disease
Patient Reported Outcomes Measures (PROM) in Carpal Tunnel Therapies in Patients With Inherited Neuropathies
The purpose of this study is to learn about focal compressive median neuropathy at the wrist (Carpal Tunnel Syndrome) and outcomes of therapies (e.g.
- Conditions
- Carpal Tunnel Syndrome, Charcot-Marie-Tooth Disease, Inherited Peripheral Neuropathy
- Trial name
- NCT02788734
- Testing
- Web-based survey
- Where
- United States
- Volunteers
- 333 people
- Sponsor
- University of South Florida
Carpal Tunnel Syndrome
Assessment of Ultrasound Findings, Nerve Test Results, and Hand Function in Patients With Carpal Tunnel Syndrome
Carpal tunnel syndrome is one of the most common conditions caused by compression of a nerve at the wrist. It can lead to numbness, tingling, pain, weakness, and difficulty performing daily activities.
- Trial name
- NCT07752797
- Testing
- Ultrasonographic and Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Sciatica
IV Paracetamol vs IV Morphine vs Placebo in Sciatalgia
Siatalgia is one of the main symptoms related to emergency department presentations. Patients with sciatalgia are seeking for immediate pain relief and little known regarding the pain management of these patients in emergency…
- Trial name
- NCT02504996
- Testing
- Paracetamol, morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Akdeniz University
Carpal Tunnel Syndrome
Finnish Carpal Tunnel Surgery Study
Carpal tunnel syndrome (CTS) is a common condition caused by pressure from a ligament on a nerve in the wrist, leading to pain, numbness, and weakness in the hand.
- Trial name
- FINCATS (NCT07614425)
- Testing
- Carpal tunnel release
- Where
- 2 sites in Finland
- Volunteers
- 180 people
- Sponsor
- Helsinki University Central Hospital
Carpal Tunnel Syndrome
Length of Post Operative Dressing After Carpal Tunnel Release
The purpose of the study is to prospectively compare the functional, satisfaction, and wound outcomes of patients treated with one of two accepted methods of postoperative dressing following carpal tunnel release.
- Trial name
- NCT01310218
- Testing
- extended postoperative dressing, short postoperative dressing
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- UConn Health
Carpal Tunnel Syndrome
Mechanisms of Neural Mobilization in the Treatment of Chronic Pain
The purpose of this study was to determine the effect of a manual therapy technique (neural mobilization) on measures of clinical pain and function, experimental pain sensitivity, and on the function of the median nerve in…
- Trial name
- NCT00929123
- Testing
- neural mobilization, healthy controls
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Florida
Stroke, Foot Drop
Effect of FES Interventions on Gait Dynamics in Stroke Population
Our proposal quantitatively analyzes gait dynamics of hemiplegic individuals in response to the Function Electrical Stimulation (FES) intervention and identifies the responders to the intervention.
- Trial name
- NCT01952613
- Testing
- FES
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Sciatica, Lumbosacral Radiculopathy
A Study of the Pharmacokinetics, Safety, and Preliminary Efficacy of MDT-15 in Subjects With Lumbosacral Radiculopathy
The primary objectives of this clinical trial are to investigate the pharmacokinetics and safety of MDT-15 pellets in escalating sequential doses administered to different cohorts.
- Trial name
- NCT01917825
- Testing
- MDT-15
- Where
- 6 sites in United States
- Volunteers
- 54 people
- Sponsor
- Medtronic Spinal and Biologics
Low Back Pain, Sciatica
Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain
The goal of this quasi-experimental trial was to evaluate the effects of non-surgical spinal decompression on disability and pain in patients with chronic low back pain and sciatica throughout a two-month follow-up, and to…
- Conditions
- Low Back Pain, Sciatica, Lumbar Disc Herniation
- Trial name
- NCT06275750
- Testing
- Spinal decompression with BTL-6000 spinal decompression system (BTL Industries Ltd.)
- Where
- Mexico
- Volunteers
- 39 people
- Sponsor
- Hospital Civil de Guadalajara