Clinical trials: Minor Stroke
Ischemic Stroke
Combining Aspirin With Ticagrelor or Clopidogrel in Large-vessel Minor Stroke or TIA
Along with the current clinical trial, the efficacy and safety of a 180 mg loading dose of ticagrelor administered within 24 hours of the first-ever large-vessel minor stroke or TIA compared to 300 mg clopidogrel were assessed…
- Trial name
- NCT06591338
- Testing
- Ticagrelor 90 MG, Clopidogrel, Aspirin 75 Mg Oral Tablet
- Where
- Egypt
- Volunteers
- 900 people
- Sponsor
- Kafrelsheikh University
Transient Ischemic Attack
Feasibility Study on the Medical and Economic Consequences of Outpatient Management of TIAs and Minor Strokes
The effectiveness of outpatient management of minor TIAs and strokes in the context of a dedicated outpatient pathway with specialized care has been demonstrated and has resulted in an 80% decrease in stroke in the year followed…
- Trial name
- MEDECO-AIT (NCT03605355)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Toulouse
Transient Ischemic Attack, Minor Ischemic Stroke
Dabigatran Following Transient Ischemic Attack and Minor Stroke
Rationale: To date, anticoagulant therapy in acute stroke has also been limited by excess hemorrhagic events. The oral anticoagulant dabigatran is a novel agent, which has been shown to be associated with much lower intracranial…
- Trial name
- DATAS II (NCT02295826)
- Testing
- Dabigatran, Acetylsalicylic acid
- Where
- 6 sites in Canada
- Volunteers
- 300 people
- Sponsor
- University of Alberta
Ischemic Stroke
Study of Tiprogrel in the Treatment of High-risk Patients with Acute Ischemic Cerebrovascular Events (THRIVE).
This study is designed to evaluate efficacy and safety of tiprogrel in the treatment of patients with acute ischemic cerebrovascular events.
- Trial name
- NCT06601127
- Testing
- Tiprogrel, Clopidogrel
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Tianjin Institute of Pharmaceutical Research Co., Ltd
Ischemia, Stroke
Edoxaban for TIA and Acute Minor Stroke
Transient ischemic attack (TIA) or minor ischemic stroke has a high risk of early recurrent stroke. As the golden standard, aspirin effect modestly on acute ischemic stroke, and slightly increase the risk of intracerebral…
- Conditions
- Ischemia, Stroke, Cerebral Infarction
- Trial name
- NCT02221102
- Testing
- Aspirin, edoxaban
- Where
- China
- Volunteers
- 3,700 people
- Sponsor
- Xijing Hospital
Ischemic Stroke, Transient Ischemic Attack
Liraglutide in Acute Minor Ischemic Stroke or High-risk Transient Ischemic Attack Patients With Type 2 Diabetes Mellitus
The purpose of this study is to assess the safety and efficacy of glucagon-like peptide-1 (GLP-1) analogue liraglutide in the treatment of acute minor stroke (National Institute of Health stroke scale, NIHSS ≤ 3) or high-risk…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Type 2 Diabetes Mellitus
- Trial name
- LAMP (NCT03948347)
- Testing
- Liraglutide
- Where
- China
- Volunteers
- 1,708 people
- Sponsor
- First Affiliated Hospital of Jinan University
Minor Stroke, Non-disabling Stroke
Stroke School -Including Physical Exercise, Patient Education and Individual Follow-up Sessions
In a randomized controlled trial the effect of 12 weeks of cross-sectorial physical exercise combined with patient education and individual follow-up session is investigated in patients with minor stroke or non-disabling stroke.
- Conditions
- Minor Stroke, Non-disabling Stroke, Transient Ischemic Attack
- Trial name
- NCT04945174
- Testing
- Cardiorespiratory exercise combined with patient education and individual follow-up sessions
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev Hospital
Transient Ischemic Attacks, Minor Stroke
The Middle East Dual Anti-platelet Treatment in Acute Transient Ischemic Attack
The primary goal of the research is to determine if 10 days of dual anti-platelet treatment is as effective as 30 days of similar treatment in the prevention of stroke, myocardial ischemia (MI) and death in patients with TIAs and…
- Trial name
- MENA-TIA (NCT02144831)
- Testing
- anti-thrombotic treatment using Aspirin (ASA 75-325mg) and Clopidogrel (75mg)
- Where
- Canada
- Sponsor
- University of Alberta
Stroke, Acute, Ischemic Attack, Transient
Sanchitongtshu Plus Asprine for Minor Ischemic Stroke or Transient Ischemic Attack: A Randomized Double-blind Study
Agents of sanchi have been widely used as a complementary medicine for stroke in China. Sanchitongshu is a new Chinese patent medicine extracted from sanchi which has stronger anti-platelet activity than other agents of sanchi.
- Trial name
- NCT02975076
- Testing
- Sanchitongshu, Aspirin, Clopidogrel
- Volunteers
- 120 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Transient Ischemic Attack
Lleida TIA Intervention Study
Having a transient ischemic attack (TIA) or a minor stroke is a real risk factor not only for early recurrent stroke but also for major extracranial vascular events.
- Trial name
- LLETIS (NCT04524078)
- Testing
- intensive integrated intervention care program
- Volunteers
- 100 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Stroke, TIA
Diabetes in Minor Stroke/TIA, Glucose Tolerance and Haemostasis, a Long-term-follow-up Study and Intervention With Yoga
In acute stroke patients about 20 % have known diabetes. There is a doubled risk of recurrent stroke in diabetic patients. It has been shown that antiplatelet drugs are not as effective in diabetic patients as in non-diabetic…
- Trial name
- NCT01648985
- Testing
- Diabetes in stroke/TIA
- Where
- Sweden
- Volunteers
- 144 people
- Sponsor
- Karolinska Institutet
Ischemic Stroke, TIA
Apixaban Versus Dual-antiplatelet Therapy (Clopidogrel and Aspirin) in Acute Non-disabling Cerebrovascular Events
Nondisabling cerebrovascular events represent the largest group of cerebrovascular disease with a high risk of recurrent stroke.
- Trial name
- ADANCE (NCT01924325)
- Testing
- Apixaban, Clopidogrel, Aspirin
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Xijing Hospital
Ischemic Stroke, Transient Ischemic Attack (TIA)
Ambulatory Stroke Unit Treatment for Elderly Patients
ARTIFICE is a prospective, multicenter, randomized, controlled, exploratory non-inferiority trial evaluating whether an ambulatory stroke unit model (aSU) is non-inferior to conventional inpatient stroke unit care (SU) in…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack (TIA), Retinal Ischemia
- Trial name
- ARTIFICE (NCT07420374)
- Testing
- Ambulatory Stroke Unit Care, Conventional Stroke Unit Care
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- University Hospital Heidelberg
Ischemic Stroke
Combining Aspirin With Cilostazol or Clopidogrel in Large-vessel Minor Stroke or TIA
Along with the current clinical trial, the efficacy and safety of a 300 mg loading dose of clopidogrel and 300 mg loading aspirin administered within 24 hours of the first-ever large-vessel minor stroke or TIA compared to 200 mg…
- Trial name
- NCT06591351
- Testing
- Cilostazol 100 MG, Clopidogrel
- Where
- Egypt
- Volunteers
- 870 people
- Sponsor
- Kafrelsheikh University
Stroke, Ischemic
Motivators and Barriers for Physical Activity in Patients With Minor Stroke
The aim of this study is to investigate motivators and barriers for physical activity in patients discharged from hospital for a minor stroke or TIA.
- Trial name
- NCT04332458
- Testing
- A focus group interview
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Herlev Hospital
Ischemic Stroke, TIA
Colchicine in High-risk Patients With Acute Minor-to-moderate Ischemic Stroke or Transient Ischemic Attack (CHANCE-3)
This study is a multicentre, randomized, double-blind, placebo-controlled, investigator-sponsored study that aims to investigate the efficacy of colchicine in preventing recurrent stroke in the patients with acute…
- Trial name
- NCT05439356
- Testing
- Colchicine
- Where
- 244 sites in China
- Volunteers
- 8,343 people
- Sponsor
- Beijing Tiantan Hospital
Stroke
Precision Reperfusion Therapy for Disabling Minor Stroke With Large Vessel Occlusion Beyond Time Window
To verify the efficacy and safety of intravenous tenecteplase (TNK) in patients with disabling minor stroke and large vessel occlusion (LVO) within a 4.5-24 hour time window.
- Trial name
- TIME-MINOR (NCT07476898)
- Testing
- Tenecteplase (0.25mg/kg), Standard Medical Management
- Where
- 30 sites in China
- Volunteers
- 864 people
- Sponsor
- First Hospital of China Medical University
Lacunar Stroke, Stroke
Lacunar Stroke hyperAcute Clinical Utilization of Novel Approach Regimens: Rt-PA vs. DAPT Randomised Clinical Trial
The goal of this clinical trial is to learn if a combination of antiplatelet drugs works better than intravenous tissue plasminogen activator to treat small ischemic stroke (lacunar stroke).
- Conditions
- Lacunar Stroke, Stroke, Ischemic Stroke
- Trial name
- LACUNAR-tPA (NCT07111559)
- Testing
- rt-PA, DAPT
- Where
- 29 sites in Japan
- Volunteers
- 500 people
- Sponsor
- Nippon Medical School
Ischemic Stroke
Combining Aspirin With Ticagrelor or Cilostazol in Large-vessel Minor Stroke or TIA
Along with the current clinical trial, the efficacy and safety of a 180 mg loading dose of ticagrelor administered within 24 hours of the first-ever large-vessel minor stroke or TIA compared to 200mg cilostazol were assessed…
- Trial name
- NCT06591377
- Testing
- Ticagrelor 90 MG, Cilostazol 100 MG, Aspirin 75mg
- Where
- 2 sites in Egypt
- Volunteers
- 900 people
- Sponsor
- Kafrelsheikh University
Stroke, Transient Ischemic Attack
Clopidogrel in High-risk Patients With Acute Non-disabling Cerebrovascular Events
The purpose of this study is to assess the effects of a 3-month regimen of clopidogrel initiated with a loading dose (LD) of 300 mg followed by 75 mg/day during the first 21days versus a 3-month regimen of ASA 75 mg/day alone on…
- Trial name
- CHANCE (NCT00979589)
- Testing
- Clopidogrel
- Where
- China
- Volunteers
- 5,100 people
- Sponsor
- Beijing Tiantan Hospital