Clinical trials: Micropulse Laser
Macular Edema Due to Type 2 Diabetes Mellitus
Efficacy Analysis of Anti-VEGF Drugs Combined With Micropulse Laser in the Treatment of Diabetic Macular Edema
The goal of this clinical trial is to clarify the efficacy of anti-vascular endothelial growth factor (anti-VEGF) drugs combined with subthreshold micropulse laser (SML) therapy on retinal function and anatomical recovery in…
- Trial name
- VEGF (NCT05759884)
- Testing
- Anti-VEGF, subthreshold micropulse laser
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Diabetic Macular Edema
Combination of Intravitreal Ranibizumab With or Without Micropulse Laser for the Treatment of DME
The objective of this study is to evaluate if combination of intravitreal ranibizumab with micropulse laser shows non inferiority compared to intravitreal ranibizumab only in diabetic macular edema.
- Trial name
- NCT03690947
- Testing
- Intravitreal Ranibizumab, Micropulse Laser, Intravitreal Ranibizumab as needed
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Beijing Hospital
Open Angle Glaucoma
Micropulse Laser Trabeculoplasty (MLT) Versus Selective Laser Trabeculoplasty (SLT) for Treatment of Open Angle Glaucoma
The purpose of this study is to evaluate the effectiveness of a new laser (called Micropulse Laser Trabeculoplasty or MLT) in the treatment of glaucoma compared to the conventional laser presently used which is called selective…
- Trial name
- NCT01956942
- Testing
- Micropulse Laser Trabeculoplasty, Selective Laser Trabeculoplasty
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- David Belyea
Glaucoma, Glaucoma, Open-Angle
Treatment Outcomes of MicroPulse Trans-scleral Cyclophotocoagulation in Uncontrolled Glaucoma
The goal of this study is to evaluate the efficacy and safety of the novel form of trans-scleral cyclophotocoagulation using micropulse diode laser and trans-pars plana treatment (Micropulse TSCPC, mTSCPC MP3, IRIDEX CYCLO G6™…
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Glaucoma, Neovascular, Glaucoma and Ocular Hypertension
- Trial name
- NCT03187418
- Testing
- MicroPulse® P3 Glaucoma Device (MP3)
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Glaucoma
Micropulse Transscleral Diode Laser Cyclophotocoagulation (MP-TSCPC) as a Treatment Modality for Glaucoma Patients
The study objective was to evaluate the efficacy and safety of transscleral cyclophotocoagulation (TSCPC) using micropulse diode laser treatment in patients with various types of glaucoma.
- Trial name
- NCT05299281
- Testing
- Micropulse transscleral cyclophotocoagulation (MP-TSCPC)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Central Serous Choroidopathy
Micropulse 577nm Laser vs Traditional Laser Treatment in Central Serous Chorioretinopathy
The purpose of this study is to observe whether micropulse laser (MPL) is noninferiority to traditional laser therapy in central serous chorioretinopathy.
- Trial name
- NCT02735213
- Testing
- 577-MPL, TLT
- Where
- China
- Volunteers
- 88 people
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Central Serous Chorioretinopathy
Two Patterns of Micropulse Laser in the Treatment of Chronic Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) is a common eye disease mainly involving the macular area, causing central visual acuity loss.
- Trial name
- NCT05687422
- Testing
- 100μm laser spot diameter micropulse laser, 200μm laser spot diameter micropulse laser
- Volunteers
- 50 people
- Sponsor
- Beijing Hospital
Central Serous Chorioretinopathy
Study on the Use of Micropulse Laser to Treat Central Serous Chorioretinopathy
The investigators hypothesis is that using the micropulse laser in patient with Central Serous Chorioretinopathy (CSC) will prompt resolution of CSC and will be effective in significantly minimizing visual recovery time from this…
- Trial name
- NCT01982383
- Testing
- Micropulse Laser Treatment, No treatment
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- George Washington University
Treatment of Refractory Glaucoma
Comparison of Outcome and Effectiveness Between Micropulse Diode Laser Cyclophotocoagulation and Cyclocryoablation in Treatment of Refractory Glaucoma
laucoma having bad prognosis after maximally tolerated medication,glaucoma that fails after filtering operations, neovascular glaucoma, glaucoma following vitrectomy and glaucoma secondary to uveitis etc.
- Trial name
- NCT05437614
- Testing
- Micropulse diode laser cyclophotocoagulation in treatment of refractory Glaucoma, Cyclocryoablation in treatment of refractory Glaucoma
- Where
- Pakistan
- Volunteers
- 47 people
- Sponsor
- University of Health Sciences Lahore
Diabetic Macular Edema
A Comparison of Standard Laser With Micropulse Laser for the Treatment of Diabetic Macular Oedema.
DIAMONDS is a Randomised Controlled Clinical Trial that is being carried out in the UK to determine the clinical effectiveness and cost-effectiveness of micropulse laser, compared with standard laser, for the treatment of…
- Trial name
- DIAMONDS (NCT03690050)
- Testing
- Diode 577 nm subthreshold micropulse laser, Standard threshold laser (532 nm laser)
- Where
- 14 sites in United Kingdom
- Volunteers
- 266 people
- Sponsor
- Belfast Health and Social Care Trust
Diabetic Retinopathy, Macula Edema
Transfoveal Micropulse Laser for Center Involving Diabetic Macular Edema
Anti-vascular endothelial growth factor (VEGF) therapy is currently the mainstay of treatment for diabetic macular edema (DME). One of the main obstacles of anti-VEGF therapy is the need of repeated injections, which carries both…
- Trial name
- NCT04359771
- Testing
- Yellow micro-pulse laser, Diode micro-pulse laser
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Cairo University
Diabetic Macular Edema
Micropulse Laser Photocoagulation in Diabetic Macular Edema
To assess the safety and efficacy of 532 nm subthreshold micropulse laser 5 % duty cycle compared with 15 % duty cycle in treatment of diabetic macular edema .
- Trial name
- NCT07266597
- Testing
- micropulse laser photocoagulation
- Volunteers
- 50 people
- Sponsor
- Sohag University
Diabetic Macular Edema
577nm Micropulse Laser Versus 532nm Subthreshold Laser Photocoagulation for Diabetic Macular Edema
This randomized, parallel controlled, clinical-trial aims to evaluate the therapeutic efficacy and safety of 577nm micropulse laser photocoagulation for diabetic macular edema compared with 532 subthreshold laser photocoagulation.
- Trial name
- NCT02406157
- Testing
- 577-MPL, 532-SLP
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Sun Yat-sen University
Severe Diabetic Macular Oedema
Anti-vascular Endothelial Growth Factor (Anti-VEGF) Monotherapy vs Anti-VEGF Followed by Subthreshold Micropulse Laser for Treating Severe Diabetic Macular Oedema When the Central Retina Goes <400 Microns
The macula is the centre of the retina; it gives central sight, colour and fine detail. People with diabetes may develop diabetic macular oedema (DMO).
- Trial name
- DAME (NCT06985706)
- Testing
- Subthreshold Micropulse Laser (SML), Anti-VEGF Monotherapy (standard care)
- Where
- 22 sites in United Kingdom
- Volunteers
- 264 people
- Sponsor
- Belfast Health and Social Care Trust
Diabetic Macular Edema
Comparing Conventional Grid Laser Photocoagulation and Subthreshold Micropulse Laser in Diabetic Macular Edema Using OCT Angiography
The prevalence of diabetes mellitus has increased significantly in Hong Kong for the past decade [1]. Diabetic macular edema is one of the most common causes of vision loss in patients suffering from diabetes mellitus [3].
- Trial name
- NCT05416099
- Testing
- laser
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Refractory Glaucoma
MicroPulse Transscleral Laser Cyclophotocoagulation With the Zig Zag Mode in Glaucoma.
This is a prospective single-arm clinical trial in which patients with neovascular or primary open angle glaucoma with uncontrolled intraocular pressure (despite maximal tolerated anti-glaucoma medical treatment) were selected…
- Trial name
- NCT05521334
- Testing
- micropulse transscleral cyclophotocoagulation
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Helwan University
Primary Open Angle Glaucoma
External Micropulse Diode Laser Transscleral Trabeculoplasty (EMDLT) for Severe Open Angle Glaucoma
To prove that external contact micropulse diode laser trabeculoplasty (EMDLT) can significantly lower intraocular pressure in cases of advanced open angle glaucoma.
- Trial name
- EMDLT (NCT00443664)
- Testing
- EXTERNAL MICROPULSE DIODE LASER TRANSSCLERAL TRABECULOPLASTY
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- National University Hospital, Singapore
Pseudoexfoliation Glaucoma, Primary Open-angle Glaucoma
Micropulse Laser Trabeculoplasty as Adjunctive Treatment in Patients With Pseudoexfoliation Glaucoma
This study aims to evaluate the effect of a single session of micropulse laser trabeculoplasty (MLT) on cornea in eyes with primary open glaucoma (POAG) and pseudoexfoliation glaucoma (PEXG).
- Trial name
- NCT03483402
- Testing
- Micropulse laser trabeculoplasty
- Volunteers
- 27 people
- Sponsor
- University Hospital of Patras
Macular Edema
Impact of the Navilas ® Micropulse Laser Treatment for Macular Edema Within the CHU Brugmann Hospital Macular Edema
The Navilas® micropulse laser can be used to treat patients with macular edema and good visual acuity, which therefore do not fall within the indications for conventional treatments by intravitreal injections.
- Trial name
- NCT04857099
- Testing
- Data extraction from medical files
- Where
- Belgium
- Volunteers
- 23 people
- Sponsor
- Brugmann University Hospital
Open-Angle Glaucoma, Ocular Hypertension
Selective, Micropulse and Pattern Laser Trabeculoplasty in Medically Treated Open-angle Glaucoma.
This randomized, single-centre, three-arm trial compared three subvisible laser trabeculoplasty delivery protocols in eyes with open-angle glaucoma already receiving intraocular pressure (IOP)-lowering medication: selective laser…
- Trial name
- NCT07756411
- Testing
- Selective laser trabeculoplasty, Micropulse laser trabeculoplasty, Pattern laser trabeculoplasty
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- University of Udine