Clinical trials: Methamphetamine Abuse
Methamphetamine Dependence, Methamphetamine Withdrawal
Characterizing Methamphetamine Withdrawal in Recently Abstinent Methamphetamine Users: A Pilot Study
Methamphetamine use has escalated in recent years. Methamphetamine use has also spread throughout the country. Although much information has been gathered on the treatment of cocaine abuse, very little information has been…
- Trial name
- NCT00653263
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Arkansas
Methamphetamine Abuse
Cognitive Behavioral Therapy(CBT) in Treatment of Methamphetamine Use Disorder
The efficacy of cognitive behavioral therapy(CBT) in treatment of methamphetamine use disorder
- Trial name
- NCT05593796
- Testing
- cognitive behavioral therapy
- Volunteers
- 50 people
- Sponsor
- Assiut University
Methamphetamine Abuse, HIV
Risky Decision Making in Methamphetamine Users: The Role of Opioid Blockade
The purpose of this protocol is to learn more about impulsive decision making in people who use methamphetamines. The investigators would like to know if a medication called naltrexone changes how people make decisions.
- Trial name
- NCT01822132
- Testing
- Extended release naltrexone
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- Oregon Health and Science University
Attention Deficit Hyperactivity Disorder
Methylphenidate on Intracortical Inhibition in Methamphetamine Abusers Attention Deficit Hyperactivity Disorder (ADHD)
Previous studies using transcranial magnetic stimulation (TMS) with paired pulse protocols have shown that a conditioning TMS pulse applied to the human motor cortex changes the excitability of motor pathways from the motor…
- Trial name
- ADHD (NCT01651169)
- Testing
- methylphenidate tablets and Inter-stimulus Intervals (ISI)
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Tehran University of Medical Sciences
Substance Use Disorders, Adolescent Behavior
Addiction in Adolescence - Pathomechanisms and Treatment Evaluation
This study aims to investigate the sociodemographic background as well as psychiatric comorbidities of adolescent substance users with substance use disorders.
- Trial name
- MATRIX-A (NCT03444974)
- Testing
- adapted treatment according to the MATRIX-A therapy
- Where
- Germany
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Methamphetamine Dependence, Methamphetamine Abuse
An ACE Inhibitor (Perindopril) or an Angiotensin Receptor Blocker (Candesartan) as a Treatment for Methamphetamine Dependence
The primary objective is to determine the dose dependent effects of treatment with perindopril on methamphetamine (MA)-induced craving and on the reinforcing effects of MA indexed by MA self-administration.
- Conditions
- Methamphetamine Dependence, Methamphetamine Abuse, Substance Abuse
- Trial name
- NCT01062451
- Testing
- Perindopril, Candesartan
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor College of Medicine
Drug Abuse, Drug Dependence
Prometa Pharmacotherapy for Methamphetamine Dependence
The purpose of this study is to assess the efficacy of the PROMETA pharmacotherapy compared to placebo for initiating abstinence and for preventing relapse to methamphetamine use in treatment-seeking individuals meeting criteria…
- Trial name
- NCT00260481
- Testing
- Prometa
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Abuse
Peer Engagement in Methamphetamine Harm-Reduction With Contingency Management (PEER-CM)
The main goal of this study is to tests the effect of incentivizing achievement of self-identified, personal harm reduction goals (Contingency management or CM) compared with standard of care (peer harm reduction service with…
- Trial name
- NCT05700994
- Testing
- Peer Contingency Management, Standard of Care Contingency Management
- Where
- 2 sites in United States
- Volunteers
- 1,283 people
- Sponsor
- Oregon Health and Science University
Substance Abuse, HIV Infections
Stonewall Treatment Evaluation Project
This treatment outcome evaluation of the Stonewall Project will recruit 150 participants to complete a face-to-face assessment visit at baseline, 3-month follow-up, and 6-month follow-up to examine treatment outcome with respect…
- Trial name
- STEP (NCT01129401)
- Testing
- Stonewall Project
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Francisco
Burns, Acute Lung Injury
Amphetamine Induced Adult Respiratory Distress Syndrome
Methamphetamine and amphetamine has various cardiovascular and central nervous system effects. Long-term use is associated with many adverse health effects including cardiomyopathy, hemorrhagic, and ischemic stroke.
- Conditions
- Burns, Acute Lung Injury, Acute Respiratory Distress Syndrome, Methamphetamine Abuse
- Trial name
- NCT05611385
- Testing
- Difference in development of Acute Lung Injury in Amphetamine positive and negative patients
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Arrowhead Regional Medical Center
Methamphetamine-dependence, Methamphetamine Abuse
Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder
The primary objective of this study is to evaluate the efficacy of extended release naltrexone plus bupropion XL (XR-NTX/BUP-XL) compared to matched injectable and oral placebo (iPLB/oPLB) in reducing methamphetamine (MA) use in…
- Trial name
- NCT06233799
- Testing
- extended-release naltrexone (XR-NTX), extended release bupropion (BUP-XL) tablets (BUP-XL), iPLB
- Where
- 11 sites in United States
- Volunteers
- 360 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Methamphetamine Abuse, Methamphetamine Dependence
Safety Assessment of Atomoxetine With MA IV Administration
This is a study of 4 nontreatment seeking individuals who were MA-dependent and the safety and tolerability of atomoxetine. This double-blind, placebo-controlled, within-subjects study is to determine the safety and tolerability…
- Trial name
- NCT01019707
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Dependence in Remission
The Efficacy of N-acetylcysteine Versus Placebo for the Treatment of Metamphetamine Withdrawal Symptoms
Up to date, no approved medications are available for the treatment of methamphetamine addiction. Recently, N-acetylcysteine is recently being studied for methamphetamine withdrawal.
- Trial name
- NCT04405193
- Testing
- N-acetyl cysteine
- Where
- Indonesia
- Volunteers
- 66 people
- Sponsor
- Melva Louisa
Methamphetamine Abuse, Pulmonary Hypertension
Screening of Pulmonary Hypertension in Methamphetamine Abusers
Methamphetamine is misuse if classified as a "likely" risk factor for pulmonary arterial hypertension (PAH). Nevertheless the actual prevalence of and a screening strategy for PAH in methamphetamine users have not been…
- Trial name
- SOPHMA (NCT04019600)
- Testing
- Echocardiography
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Methamphetamine Dependence, Substance Abuse
Varenicline vs Placebo for the Treatment of Methamphetamine Dependence
Methamphetamine (MA) abuse is the fastest growing drug problem in the United States and is responsible for significant public health complications, including HIV infection.
- Conditions
- Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
- Trial name
- RAVEN (NCT01011829)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Methamphetamine Abuse
Field Study of a Digital Therapeutic Platform to Facilitate Treatment for Methamphetamine-Primary Stimulant Use Disorder
The overall purpose of the observational, investigational pilot study is to assess the clinical utility of the Affect digital health platform (the Affect® "app") as part of the Affect program of treatment for…
- Trial name
- NCT05266716
- Testing
- Affect Methamphetamine Treatment Program
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Affect Therapeutics, Inc.
Methamphetamine Dependence, Methamphetamine Abuse
Varenicline as a Treatment for Methamphetamine Dependence
The primary purpose of the study is to determine the effects of treatment with varenicline (1 and 2 mg daily), compared to treatment with placebo, on methamphetamine-induced craving and subjective effects in…
- Conditions
- Methamphetamine Dependence, Methamphetamine Abuse, Substance Abuse
- Trial name
- Varenicline (NCT01571167)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Baylor College of Medicine
Methamphetamine Abuse, Methamphetamine-dependence
Clinical Trial of High Dose Lisdexamfetamine and Contingency Management in MA Users
The goal of this clinical trial is to learn if administering a high dose stimulant with Contingency Management reduces days of use in adults who use methamphetamine better than the usual treatment provided by the clinic.
- Conditions
- Methamphetamine Abuse, Methamphetamine-dependence, Addiction, Substance, Addiction
- Trial name
- NCT05854667
- Testing
- Treatment as Usual plus lisdexamfetamine (LDX-01), Treatment as Usual plus lisdexamfetamine (LDX-01) plus Contingency Management
- Where
- 4 sites in Canada
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Behavior and Mental Disorders, Methamphetamine Disorders
Development of a Family-Based Treatment for Adolescent Methamphetamine Use
The AIMS study compares a methamphetamine-specific treatment intervention to a treatment-as-usual Functional Family Therapy (FFT) approach for adolescents ages 15 to 19.
- Trial name
- AIMS (NCT00680511)
- Testing
- Adolescent Methamphetamine Treament (AMT), Functional Family Therapy (FFT)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Methamphetamine Use Disorder
Accelerated Development of Additive Pharmacotherapy Treatment (ADAPT-2) for Methamphetamine Use Disorder
This is a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy of extended-release naltrexone plus bupropion as a combination pharmacotherapy for methamphetamine use disorder.
- Trial name
- ADAPT-2 (NCT03078075)
- Testing
- Naltrexone: Vivitrol®, Bupropion: Wellbutrin XL®
- Where
- 8 sites in United States
- Volunteers
- 403 people
- Sponsor
- University of Texas Southwestern Medical Center