Clinical trials: Mesenteric Vascular Disease
Mesenteric Ischemia, Bowel; Ischemic
Copenhagen Mesenteric Stent Study - A Randomized Trial of Stent Versus Covered Stent Treatment for Chronic Mesenteric Ischemia
Chronic mesenteric ischemia (CMI) is often caused by narrowings in the arteries providing blood to the intestines. Endovascular stent placement is considered the preferred treatment for this condition.
- Conditions
- Mesenteric Ischemia, Bowel; Ischemic, Superior Mesenteric Atherosclerosis, Mesenteric Artery Stenosis
- Trial name
- COMESS (NCT05244629)
- Testing
- BMS vs. CS
- Where
- Denmark
- Volunteers
- 98 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Visceral Artery Aneurysm, Mesenteric Artery Ischemia
European Multicentre Study of Long-term Results Following Visceral Arteries Revascularization: the E-VisAR Study
Visceral arteries pathologies are a broad-spectrum of conditions with an extremely low incidence, estimated at 9.2% and 6.2% per 100,000 inhabitants for chronic and acute mesenteric ischemia, respectively, and 0.01-0.2% for…
- Conditions
- Visceral Artery Aneurysm, Mesenteric Artery Ischemia, Renal Artery Aneurysm, Renal Artery Stenosis
- Trial name
- E-VisAR (NCT06913530)
- Volunteers
- 500 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Laparotomy, Bowel Obstruction
Early vs Postponed Parenteral Nutrition After Emergency Abdominal Surgery
The aim of this study is to investigate the effect of early, supplementary parenteral nutrition following emergency laparotomy. Currently, parenteral nutrition is used in postoperative patients if or when oral or enteral…
- Conditions
- Laparotomy, Bowel Obstruction, Ischemia, Mesenteric
- Trial name
- EATERS (NCT06089551)
- Testing
- SmofKabiven
- Where
- Denmark
- Volunteers
- 342 people
- Sponsor
- Copenhagen University Hospital at Herlev
Thoracic Aortic Aneurysms, Dissecting, Aneurysm
Endovascular Treatment of Thoracic Aortic Disease
The purpose of this study is to assess the role endovascular therapy to treat aortic disease involving the ascending aorta, the aortic arch, and the visceral segment of the aorta (or thoracoabdominal aorta)
- Conditions
- Thoracic Aortic Aneurysms, Dissecting, Aneurysm, Ascending Aorta Aneurysm, Aortic Arch; Aneurysm, Dissecting
- Trial name
- EVOLVE Aorta (NCT00583817)
- Testing
- Endovascular stent-graft implantation
- Where
- 2 sites in United States
- Volunteers
- 170 people
- Sponsor
- Matthew Eagleton
Mesenteric Ischemia
Predictive Factors of Intestinal Infraction in Acute Mesenteric Ischemia
The study aims to identify several factors that can accurately predict the incident of intestinal infraction in patients with mesenteric vascular occlusion or ischemia.
- Trial name
- NCT02645240
- Testing
- Heparin injection
- Where
- Egypt
- Volunteers
- 97 people
- Sponsor
- Mansoura University
Portal Vein Thrombosis, Mesenteric Vein Thrombosis
Treatment of Splanchnic Vein Thrombosis With Rivaroxaban. A Pilot, Prospective Cohort Study
Anticoagulant therapy is generally recommended for all patients presenting with acute symptomatic splanchnic vein thrombosis, starting with either low-molecular weight heparin (LMWH) or unfractionated heparin and continuing with…
- Conditions
- Portal Vein Thrombosis, Mesenteric Vein Thrombosis, Splenic Vein Thrombosis
- Trial name
- NCT02627053
- Testing
- rivaroxaban
- Where
- 4 sites in Canada, Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Submucosal Tumor of Gastrointestinal Tract, Gastrointestinal Stromal Tumor (GIST)
Mesenteric Vascular Preconditioning Combined With Laparoscopic and Endoscopic Cooperative Surgery for Submucosal Tumor at the Gastroesophageal Junction
This study is a single-center, prospective, single-arm, exploratory clinical study (phase II exploratory trial). No parallel control group was established in the study, and all subjects who met the inclusion criteria underwent a…
- Trial name
- SAVE-GEJ (NCT07550582)
- Testing
- laparoscopic and endoscopic cooperative surgery
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University People's Hospital
Mesenteric Artery Ischemia
Incidence, Treatment and Outcome After Acute Mesenteric Ischemia in the Region of Västra Götaland, 2000-2023.
The goal of this retrospective observational study is to describe the incidence and outcome of patients diagnosed with acute mesenteric ischemia (AMI) in the Västra Götaland region of Sweden between 2000-2023.
- Trial name
- AMIGO (NCT07274306)
- Where
- 2 sites in Sweden
- Volunteers
- 2,446 people
- Sponsor
- Sahlgrenska University Hospital
Mesenteric Vein Thrombosis
Acute Mesenteric Venous Thrombosis.. in Assiut University Hospital Management Controversies
Initial treatment in the management of acute mesenteric vein thrombosis (MVT) is controversial. Some authors have proposed a surgical approach, whereas others have advocated medical therapy (anticoagulation).
- Trial name
- NCT03483207
- Testing
- Warfarin, MVT with failure of anticoagulation therapy, Heparin
- Volunteers
- 30 people
- Sponsor
- Assiut University
Intracranial Aneurysm
Aneurysmal Subarachnoid Hemorrhage and Superior Mesenteric Artery Flow Study
The purpose of this research study is to determine if the diameter and flow of the superior mesenteric artery in patients with aneurysmal subarachnoid hemorrhage undergoing hypertensive therapy for cerebral artery vasospasm are…
- Trial name
- NCT02684500
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Florida
Chronic Mesenteric Ischemia, Median Arcuate Ligament Syndrome
Intestinal Ischemia Biomarker in Patients With Chronic Mesenteric Ischemia
Plasma Alpha glutathione S transferase (Alpha GST) has been previously demonstrated to be raised in patients with chronic mesenteric ischemia (CMI) caused by atherosclerosis and in patients with median arcuate ligament syndrome…
- Conditions
- Chronic Mesenteric Ischemia, Median Arcuate Ligament Syndrome, Crohn Disease, Cholelithiasis
- Trial name
- NCT06468774
- Testing
- Laparoscopic surgery
- Where
- Norway
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Colorectal Cancer
Influence of the Surgical Technique Used for Colectomies on the Concentration of Circulating Tumor DNA and the Presence of Circulating Tumor Cells: Comparison of the "no Touch" Technic With Either First Clamping of the Mesenteric Vessels or First Mobilization of the Tumor Followed by Clamping.
Colectomy is the most commonly used therapeutic approach for the treatment of non-metastatic colorectal cancer. This approach is generally very effective however the rate of recurrence and the appearance of metachronous…
- Trial name
- ADNCHIR (NCT03809403)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mesenteric Ischemia
Cohort SURVI : Intestinal Ischemia and Vascular Diseases
The first Intestinal Vascular Emergency Unit (SURVI), with the institutional support of AP-HP, opened on 4 January 2016, within the Paris-Nord Val de Seine University Hospital Group.
- Trial name
- Survibase (NCT04746534)
- Where
- France
- Volunteers
- 20,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Endometriosis, Bowel Endometriosis
Mesenteric Sparing Surgery in Laparoscopic Colorectal Resection for Endometriosis
Colorectal resection is a standard surgical treatment of bowel deep infiltrating endometriosis (DIE). Nevertheless, concerns about different bowel functional outcomes related to radical surgery versus conservative surgery as…
- Conditions
- Endometriosis, Bowel Endometriosis, Constipation
- Trial name
- IRE-1 (NCT03565848)
- Testing
- Mesenteric vascular and nerve sparing surgery in laparoscopic segmental colorectal resection
- Volunteers
- 50 people
- Sponsor
- Università degli Studi dell'Insubria
Pregnancy Related
Diagnostic Performance of Antenatal Ultrasound for High-Risk Intestinal Malrotation
The aims of this study are: To assess the performance of third-trimester ultrasound scan in the localization of intestinal structures (small bowel, gut, mesenteric vessels..) involved in malrotations with a higher-risk of…
- Trial name
- MALGRE (NCT03968107)
- Testing
- Reference ultrasound examination
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Mesenteric Vascular Disease, Colorectal Surgery
Anastomotic Leakage Prevention by Endovascular Stenting of the Superior Mesenteric Artery
Rationale: Anastomotic leakage (AL) is a severe complication of colon surgery, with an incidence of 2.7-11.9%. It is associated with long-term increased mortality, reduced quality of life, and high healthcare costs due to…
- Conditions
- Mesenteric Vascular Disease, Colorectal Surgery, Preventive Intervention
- Trial name
- ALPrES²MA (NCT07486570)
- Testing
- Percutaneous transluminal angiopasty and endovascular stenting of the superior mesenteric artery, Colon surgery, Mono antiplatelet therapy with Ascal 80mg daily
- Where
- 18 sites in Netherlands
- Volunteers
- 360 people
- Sponsor
- Medisch Spectrum Twente
Ischemia, Fatty Acid-Binding Proteins
Kidney and Intestinal Markers for Early Detection of Organ Injury After Endovascular Aortic Repair
This study aims to investigate the predictive value of novel biomarkers and contrast-enhanced ultrasonography for early detection of abdominal end-organ (kidney and intestinum) hypoperfusion and ischemia in patients undergoing…
- Conditions
- Ischemia, Fatty Acid-Binding Proteins, Mesenteric Vascular Disease, Acute Kidney Injury
- Trial name
- KISMED (NCT01915446)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Regensburg
Mesenteric Ischemia
Serum Lactate in Acute Mesenteric Ischemia
Background: Acute mesenteric ischemia is a vascular emergency with high mortality because of ambiguous symptomatology and a lack of early diagnostic markers.
- Trial name
- NCT04671979
- Testing
- Lactate Dehydrogenase
- Where
- Colombia
- Volunteers
- 74 people
- Sponsor
- Universidad del Rosario
Ultra-trail Participation
Evaluation of Biological Markers of Mesenteric Ischemia During an Ultra-trail
To assess the evolution of biological markers of mesenteric ischemia during ultratrail.
- Trial name
- ISKETRAIL (NCT03205098)
- Testing
- Blood analysis
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Rectal Cancer
PROSPECTIVE CONTROLLED AND RANDOMIZED STUDY OF THE GENITOURINARY FUNCTION AFTER RECTAL CANCER SURGERY IN RELATION TO THE DISSECTION OF THE INFERIOR MESENTERIC VESSELS
Purpose: The "Total Mesorectal Excision" (TME) is the standard surgical technique for the treatment of rectal cancer. Up to 50% of sexual dysfunction is described after TME and up to 30% of urinary dysfunction.
- Trial name
- NCT03520088
- Testing
- Inferior mesenteric Vein dissection, Inferior mesenteric Artery dissection
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Corporacion Parc Tauli