Clinical trials: Menstrual Migraine
Transformed Migraine, Chronic Daily Headache
Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines
This study will compare a local anesthetic technique that has been used to treat subjects suffering from transformed migraines (chronic migraines) versus medical management with traditional antidepressant Amitriptyline / Elavil.
- Trial name
- NCT02090998
- Testing
- SPG Block with 5% Lidocaine gel, Amitriptyline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rutgers, The State University of New Jersey
Menstrually Associated Migraine
A Randomized Trial of Frovatriptan for the Intermittent Prevention of Menstrual Migraine
The primary objective of this study was to determine whether frovatriptan was effective in the prevention of menstrually associated migraine (MAM) headaches when compared to placebo.
- Trial name
- NCT00644033
- Testing
- Frovatriptan
- Where
- United States
- Volunteers
- 579 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Menstrual Migraine
CGRP, Estrogen, Cortisol, VIP, α-Amylase, PGE2, PGI2 and ß-Endorphin Levels in Menstrual Migraine Before and After Treximet
The purpose of this study is to (1) evaluate pain-free efficacy of Treximet™ following treatment of menstrual migraine, (2) investigate levels of Calcitonin gene-related peptide (CGRP), estrogen, cortisol, vasoactive intestinal…
- Trial name
- NCT01329562
- Testing
- Treximet
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Cady, Roger, M.D.
Migraine
Study to Test a Marketed Drug in the Treatment of Menstrual Migraine (0462-071)
The purpose of this study is to test the effectiveness of a marketed drug in the treatment of a menstrual migraine attack.
- Trial name
- NCT00111709
- Testing
- MK0462, rizatriptan benzoate / Duration of Treatment -1 day
- Volunteers
- 393 people
- Sponsor
- Organon and Co
Menstrual Migraine (MM)
Study of Oral Atogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine
A migraine attack is a moderate or severe headache that usually occurs on one side of the head and is often throbbing or pulsating.
- Trial name
- ATO MM (NCT06806293)
- Testing
- Atogepant
- Where
- 95 sites in China, Czechia and 10 more
- Volunteers
- 468 people
- Sponsor
- AbbVie
Cystitis, Interstitial, Dysmenorrhea
Chronic Pain Risk Associated With Menstrual Period Pain
The purpose of this study is to determine if some women with dysmenorrhea (painful periods) are at higher future risk of developing chronic pelvic pain (CPP) and if oral contraceptives (OC) can be used to reverse this chronic…
- Conditions
- Cystitis, Interstitial, Dysmenorrhea, Migraine Disorders, Pelvic Pain
- Trial name
- CRAMPP (NCT02214550)
- Testing
- cyclic microgestin 1/20, continuous microgestin 1/20
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Menstrual Migraine
An Investigation of the Safety and Utility of Treximet in the Treatment of Menstrual Migraine
The study is to primarily investigate whether Treximet® (Imitrex RT/naproxen sodium 500mg) taken at the first onset of menstrual migraine will both terminate the acute headache and assist in preventing headache recurrence and the…
- Trial name
- NCT01578941
- Testing
- Diary
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Alabama at Birmingham
Menstrual Migraine
Fremanezumab for the Prevention of Menstrually-related Migraine Attacks
The goal of this observational study is to compare, in real-world clinical practice, the effect of fremanezumab on menstrual migraine to the effect of fremanezumab on non-perimenstrual attacks.
- Trial name
- FROMM (NCT06659120)
- Testing
- Fremanezumab
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Menstrual Migraine
A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine
The purpose of this study is to evaluate the efficacy and safety of rimegepant when administered during the peri-menstrual period (PMP) for intermittent prevention of migraine in women who experience menstrual migraine attacks.
- Trial name
- NCT06641466
- Testing
- Rimegepant, Standard of Care
- Where
- 123 sites in United States, Argentina and 13 more
- Volunteers
- 723 people
- Sponsor
- Pfizer
Menstrual Migraine
A Study Investigating the Efficacy and Safety of Sepranolone in Women With Menstrual Migraine
The objective of this phase 2 Proof.of Concept study is to evaluate the efficacy and safety of Sepranolone (UC1010) in preventing menstrual migraine attacks in adult women with migraine occurring between Day -2 and Day 5 of the…
- Trial name
- APH204 (NCT04102995)
- Testing
- Sepranolone injection low dose, Sepranolone injection high dose
- Where
- 7 sites in Finland, Sweden
- Volunteers
- 86 people
- Sponsor
- Asarina Pharma
Menstrual Migraine
Comparison of the Prophylactic Effect Between Acupuncture and Acupressure on Menstrual Migraine
This study is designed to make comparisons between acupuncture and acupressure for preventing menstrual migraine (MM). Whether acupuncture is superior to acupressure is the most interesting point of this study.
- Trial name
- NCT02592681
- Testing
- verum acupuncture, acupressure, control acupuncture
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Migraine, Migraine;Menstrual
The Effect of Topiramate on Etonogestrel Concentrations in Contraceptive Implant Users
A prospective, non-inferiority study to evaluate the pharmacokinetic effect of topiramate on serum Etonogestrel (ENG) levels in contraceptive implant users.
- Conditions
- Migraine, Migraine;Menstrual, Contraception
- Trial name
- NCT03335163
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Menstrual Migraine (MM) Headaches
Effectiveness And Safety Of Frovatriptan For The Management (Acute Treatment) Of Menstrual Migraine
Females 18 years of age or older with at least one year history of menstrual migraine (MM) headaches participated in a Phase 4 clinical trial to evaluate the efficacy of frovatriptan when used at the early stage (International…
- Trial name
- NCT00904098
- Testing
- Frovatriptan, Usual Care
- Where
- 21 sites in United States
- Volunteers
- 192 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Migraine, Migraine Disorders
Menstrual Migraine Treatment With TREXIMET (Formerly Known as TREXIMA)
This study was designed to determine efficacy of TREXIMET (sumatriptan/naproxen sodium), formerly known as TREXIMA compared to placebo for the treatment of a menstrual migraine.
- Trial name
- NCT00329355
- Testing
- sumatriptan succinate/naproxen sodium
- Where
- 35 sites in United States
- Volunteers
- 351 people
- Sponsor
- GlaxoSmithKline
Migraine Disorders
Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as TREXIMA, for Menstrual Migraine in Women With Dysmenorrhea
This study was designed to determine efficacy of TREXIMA compared to placebo for the treatment of a menstrual migraine.
- Trial name
- NCT00329459
- Testing
- sumatriptan succinate/naproxen sodium
- Where
- 34 sites in United States
- Volunteers
- 320 people
- Sponsor
- GlaxoSmithKline
Migraine, Menstrual Migraine
Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45
The goal of this clinical trial is to learn about how a migraine prevention medicine works for people who have migraines/headaches with their menstrual period.
- Conditions
- Migraine, Menstrual Migraine, Menstrually Related Migraine
- Trial name
- NCT06173661
- Testing
- Fremanezumab
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Brigham and Women's Hospital
Migraine
Treatment of Menstrual Migraine With Sequential, Transdermal, 17-Beta-Estradiol. A Double-Blind, Randomised, Cross-Over Trial.
The purpose of this study is to determine whether transdermally administered 17-beta estradiol sequentially could reduce the number of, and severity of, menstrual migraine attacks.
- Trial name
- NCT00204074
- Testing
- 17-beta-estradiol (drug)
- Where
- Sweden
- Sponsor
- University Hospital, Linkoeping
Migraine, Migraine;Menstrual
Oral Contraceptive Pill Compared With Vitamin E in Women With Migraine
Open-label randomized controlled trial to study the efficacy of continuous daily use of ethinylestradiol/levonorgestrel (30/150 µg/day) compared with vitamin E (400 IU/day) in the treatment of women with menstrually-related and…
- Trial name
- WHATT (NCT04007874)
- Testing
- Ethinylestradiol/levonorgestrel, Vitamin E
- Where
- Netherlands
- Volunteers
- 360 people
- Sponsor
- Leiden University Medical Center
Migraine
Study of the Molecular Genetics of Menstrual Migraine
The investigators hypothesize that genes that play a role in menstrual migraine can be identified using a well characterised migraine population and a comprehensive genome-wide association scan approach.
- Trial name
- NCT00904150
- Where
- United Kingdom
- Volunteers
- 585 people, healthy volunteers welcome
- Sponsor
- The City of London Migraine Clinic
Menstrual Migraine
Intracranial Pressure During Migraine
An increase in intracranial pressure (ICP) during migraine attacks is possible and could contribute to pain initiation and maintenance. From now on, it was not possible to measure ICP in a non-invasive way.
- Trial name
- MigICP (NCT03152305)
- Testing
- Intracranial pressure variations
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand