Clinical trials: Menopause Symptoms
Menopause-Hot Flashes
Flushes and Sertraline Trial
The primary outcome of FAST (a randomized double-blinded, placebo controlled, trial of the effect of sertraline vs. placebo in reducing the incidence and severity of hot flushes in healthy women) is to determine if 6 weeks of…
- Trial name
- NCT00283192
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Menopause, Vulvovaginal Atrophy
TXV13-01 Estradiol Vaginal Softgel Capsules in Treating Postmenopausal Women With Symptoms of Vulvar and Vaginal Atrophy
The study was designed to evaluate the efficacy and safety of TX-12-004-HR 10 μg in treating moderate to severe symptoms of vaginal atrophy associated with menopause after 14 days of treatment, and to estimate the effect size and…
- Conditions
- Menopause, Vulvovaginal Atrophy, Painful Intercourse, Dyspareunia
- Trial name
- NCT02449902
- Testing
- Estradiol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- TherapeuticsMD
Climacteric Syndrome, Postmenopausal Symptoms
Multimodal Program for Climacteric Women
Your study seems to aim at emphasizing the significance of non-pharmacological and non-hormonal approaches in managing menopausal symptoms, particularly focusing on muscle training and education.
- Conditions
- Climacteric Syndrome, Postmenopausal Symptoms, Menopause, Perimenopausal Disorder
- Trial name
- NCT06419972
- Testing
- multimodal physiotherapy programme
- Where
- 2 sites in Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Menopause Syndrome, Menopause
A Study of NOE-115 in Women With Vasomotor Symptoms Due to Menopause
The purpose of this study is to determine the safety, tolerability, and preliminary effectiveness of NOE-115 on moderate to severe vasomotor symptoms (hot flashes) due to menopause in women.
- Conditions
- Menopause Syndrome, Menopause, Hot Flashes
- Trial name
- NCT06385795
- Testing
- NOE-115
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Noema Pharma AG
Breast Cancer, Fertility
Intervening on Women's Health for Rural Young Breast Cancer Survivors
The purpose of this study is to evaluate the effectiveness of a multi-component intervention to improve young breast cancer survivors' engagement in goal-concordant oncofertility care, concurrently with observing and gathering…
- Conditions
- Breast Cancer, Fertility, Contraception, Menopausal Symptoms
- Trial name
- NCT05414812
- Testing
- Multi-component oncofertility care intervention
- Where
- 4 sites in United States
- Volunteers
- 81 people
- Sponsor
- University of California, San Diego
Aging, Menopause
Gonadal Hormone, Gonadotropin and Cardiovascular Events
Deficiency in gonadal hormone has been considered to play a role in ageing related increased incidence of cardiovascular events. But the mechanism has not been fully elucidated.
- Trial name
- NCT02810821
- Where
- China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Menopause
Efficacy and Safety of S-equol on Vasomotor Symptoms in Menopausal Patients
The purpose of this study is to assess the safety and effectiveness of S-equol in menopausal patients with hot flushes and night sweats.
- Trial name
- NCT00962585
- Testing
- S-equol
- Where
- 9 sites in United States, Australia
- Volunteers
- 169 people
- Sponsor
- Ausio Pharmaceuticals, LLC
Pelvic Organ Prolapse, Menopause
Effect of Preoperative Estrogen Treatment on Connective Tissues of the Pelvic Floor
This is a study to determine how vaginal estrogen cream given for several weeks before pelvic reconstructive therapy will effect elastic fiber assembly in the muscularis layer of the vaginal wall.
- Trial name
- PET (NCT01778985)
- Testing
- Premarin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Menopause
Dose Finding Evaluation of Kudzu Root Extract in Women With Menopause Symptoms
The aim of the study is to investigate effects of daily intake of Nordic Kudzu for 28 days in 5 groups of 10 menopausal women with symptoms.
- Trial name
- KUDZU-01 (NCT04552106)
- Testing
- 3 caps x3/day, 3 caps x2/day, 2 caps x3/day
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Nordic Bioscience A/S
Psychological Distress, Quality of Life and Menopause
The Effect of Continuous Care Model on Psychological Distress and Quality of Life Among Postmenopausal Women With Urinary Incontinence
This research aimed to evaluate the effect of continuous care model on psychological distress and quality of life among postmenopausal women with urinary incontinence.
- Trial name
- NCT07538752
- Testing
- Continuous Care Model sessions
- Where
- Palestinian Territories
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Al-Quds University
Menopausal and Postmenopausal Women
Relaxation Training for Menopausal and Postmenopausal Women
Relaxation training is one of the methods used in the reduction of many menopausal symptoms such as vasomotor symptoms, sleep disturbance, and emotional status changes.
- Trial name
- NCT07158320
- Testing
- Relaxation training
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Baskent University
Menopause, Sleep
The Effect of Interactive Game Supported Sleep Hygiene Training on Sleep Quality, Menopausal Symptoms and Quality of Life in Menopausal Women
This study will present an innovative approach for sleep hygiene education in this age group by developing an interactive game-based education model for menopausal women.
- Trial name
- NCT06750562
- Testing
- interactive game
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Meryem Vural Şahin
Sleep Initiation and Maintenance Disorders, Depression
Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia
This study will evaluate the effectiveness of estrogen replacement therapy in treating depression in menopausal women with hot flashes and insomnia.
- Trial name
- NCT00227942
- Testing
- Estrogen Replacement Therapy, Zolpidem
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hadine Joffe, MD
Postmenopausal Atrophic Vaginitis, Postmenopausal Symptoms
LASER and Radiofrequency and Genitourinary Syndrome of Menopause
This is a randomized controlled trial to evaluate the use of LASER, Micro Ablative radiofrequency and topic strogen to treat symptoms of vulvovaginal atrophy of post menopause.
- Conditions
- Postmenopausal Atrophic Vaginitis, Postmenopausal Symptoms, Genitourinary Symptoms
- Trial name
- EPMLARF-arm1 (NCT04045379)
- Testing
- LASER, Microablative Radiofrequency, Estriol
- Where
- Brazil
- Volunteers
- 195 people
- Sponsor
- Federal University of São Paulo
Post Menopausal
Effects of Progressive Resistance Training Vasomotor Symptoms in Post Menopausal Women
The study will be a randomized clinical trial and will be conducted in Civil Hospital and Kalsoom Hospital Samundry. This study will be completed in time duration of 10 months after the approval of synopsis.
- Trial name
- NCT06166264
- Testing
- Progressive resistance training, Control group
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Urinary Incontinence
Comparison Between Pelvic Muscle Training and Pilates Exercises for UI in Postmenopausal Women
Introduction: Urinary incontinence (UI) is a condition that affects around 40% of postmenopausal women and is therefore considered a public health problem.
- Trial name
- NCT05446792
- Testing
- PFMT, PE
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Norte do Parana
Menopause
Effect of Red Clover on Menopause Symptoms and Lipid Profile
The goal of this clinical trial is to investigate the effects of red clover isoflavones on menopausal symptoms and lipid profile in menopausal females.This prospective randomized, double-blind, placebo-controlled study included…
- Trial name
- NCT06209697
- Testing
- red clover
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Medipol University
Menopause, Metabolic Syndrome
Lacto-ovo-vegetarian Diet Riched in Omega-3 Fatty Acids in Menopausal Women
Healthy lifestyle, based on healthy diet and exercise, is a key factor to prevent the most common menopausal disorders and chronic diseases to which women are more exposed during this life stage.
- Conditions
- Menopause, Metabolic Syndrome, Hepatic Steatosis
- Trial name
- NCT02816814
- Testing
- Diet rich in omega-3 fatty acids, Diet with extra virgin olive oil
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Women With Breast Cancer
Effect of Intravaginal Prasterone on Symptoms of Genitourinary Syndrome of Menopause (GSM) in Women in Menopause With Previous Breast Cancer
The goal of this interventional study is to evaluate the effect of Intravaginal Prasterone for the treatment of moderate to severe symptoms of genitourinary syndrome (GSM) due to natural, surgical or treatment-induced menopause…
- Trial name
- PROPOSE (NCT06611514)
- Testing
- Prasterone (DHEA)
- Where
- Italy
- Volunteers
- 95 people
- Sponsor
- European Institute of Oncology
Menopause
Menopausal Symptoms Probiotic Study
In this study, we want to investigate if the active product consisting of a probiotic blend can potentiate the recirculation of active oestrogens into the bloodstream and help to mitigate menopause symptoms, which are closely…
- Trial name
- NCT06446869
- Testing
- Gyntima Menopause
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- Community Pharmacology Services Ltd