Clinical trials: Meniscus Lesion
Osteoarthritis, Knee, Knee Injuries
Impact of Mulligan Squeeze Technique on Meniscal Derangement in Knee Osteoarthritis Patients
The objective of this study is to find out the effects of Mulligan's Squeeze technique added as a complementary treatment to the conventional physiotherapy for the management of meniscal derangement in knee osteoarthritis…
- Conditions
- Osteoarthritis, Knee, Knee Injuries, Meniscus; Derangement, Meniscus Tear
- Trial name
- NCT06391047
- Testing
- Mulligan's Squeeze Technique - manual therapy, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Faisalabad
Meniscus Injury, Osteoarthritis, Knee
The Effect of Commercially Available Footwear Interventions in Meniscectomy Patients
Injuries to the meniscus are common in sport. A meniscectomy is often performed to manage symptoms associated with the meniscal injury. Following a meniscectomy individuals are highly likely to develop knee osteoarthritis (OA).
- Conditions
- Meniscus Injury, Osteoarthritis, Knee, Footwear
- Trial name
- MENI-FOOT (NCT03379415)
- Testing
- Footwear, Gait analysis
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Salford
Meniscus Injury
Efficacy and Safety of FF-31501 in Meniscus Tear Patients
A single-arm, multi-center study to verify that knee joint function at 52 weeks after injection of FF-31501 is better than at screening in patients with meniscus tear who are eligible for meniscectomy .
- Trial name
- NCT05777967
- Testing
- human autologous synovial stem cells
- Where
- 4 sites in Japan
- Volunteers
- 18 people
- Sponsor
- FUJIFILM Toyama Chemical Co., Ltd.
Meniscus Lesion
Comparison of the Effectiveness of Single and Dual Task Training Applied to Individuals With Knee Meniscus Lesion
The main function of the meniscus is to transfer and distribute femoral pressure to the tibia. Treatment of meniscus tears is divided into conservative and surgical treatment.
- Trial name
- NCT06886542
- Testing
- Dual task training, Single task training, Conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ankara Yildirim Beyazıt University
Cartilage Diseases
Sampling Biomarkers in Meniscus Injury to the Knee
The diagnosis of clinically-significant meniscal tears of the knee remains challenging, and it is unknown why only some injuries become painful.
- Trial name
- NCT00836966
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Scuderi, Gaetano J., M.D.
Meniscus Lesion, Knee Injuries
"Intra-articular Hyaluronic Acid Injection for Accelerating Functional Recovery After Knee Arthroscopy"
This study evaluates the effectiveness of intra-articular hyaluronic acid (HA) viscosupplementation and oral chondroitin sulfate (CS) supplementation, in combination with standard postoperative rehabilitation, on functional…
- Conditions
- Meniscus Lesion, Knee Injuries, Medial Meniscus Tear
- Trial name
- NCT07476508
- Testing
- Standard Postoperative Rehabilitation Protocol, Oral Chondroitin Sulfate (Flextrum), ntra-articular Hyaluronic Acid Injection (Biolevox)
- Where
- 2 sites in Poland
- Volunteers
- 290 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Meniscus Injury, Meniscectomy
Biomechanical Osteoarthritis Outcomes in Meniscectomy Patients
The key aim of this study is to examine biomechanical measures associated with osteoarthritis (OA) progression in patients who have lateral and medial menisci injuries during various tasks.
- Conditions
- Meniscus Injury, Meniscectomy, Osteoarthritis, Knee
- Trial name
- BOOM (NCT03350204)
- Testing
- Meniscectomy, Helathy control comparison
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Salford
Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear
Clinical Efficacy of Exosome in Degenerative Meniscal Injury
Comparison of intra-articular administration of synovial fluid-derived mesenchymal stem cells-derived exosomes with synovial fluid-derived mesenchymal stem cells on the same patient.
- Conditions
- Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear, Meniscus Lesion, Meniscus; Degeneration
- Trial name
- KNEEXO (NCT05261360)
- Testing
- SF-MSC-EX, SF-MSC
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Eskisehir Osmangazi University
Meniscus Tear, Meniscus; Derangement
Enhancing Recovery Through a Combined Mechanobiologic Intervention Following Meniscus Repair
Arthroscopic meniscal procedures are the most commonly performed orthopaedic procedure in the U.S. affecting 15% of Americans ages 10-65 years.
- Conditions
- Meniscus Tear, Meniscus; Derangement, Meniscus Lesion, Meniscus Disorder
- Trial name
- NCT05505747
- Testing
- Fisetin
- Where
- United States
- Sponsor
- Austin V Stone
Meniscus Rupture, Meniscus Injury
Surgical Outcome After Displaced Bucket-handle Meniscal Lesions - Repair Versus Partial Meniscectomy
The menisci of the knee joint are structures composed of cartilage and connective tissue, whose primary functions are to stabilize the joint and distribute weight across joint surfaces.
- Conditions
- Meniscus Rupture, Meniscus Injury, Osteoarthritis of Knee
- Trial name
- NCT07079254
- Testing
- Meniscus suture, Partial meniscectomy
- Where
- 2 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Region Skane
Chronic Meniscal Injury
Mesenchymal Stromal Cells for Degenerative Meniscus Injury
The present proposal has the objective to assess whether the addition of autologous ex vivo expanded mesenchymal stromal cells (XCEL-M-ALPHA) to the conventional meniscal injury rehabilitation program is contributing in creating…
- Trial name
- NCT02033525
- Testing
- XCEL-M-ALPHA and standard rehabilitation, Rehabilitation
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Banc de Sang i Teixits
Meniscus Injury, Meniscus Tear
Assessment of Quadriceps Femoris Muscle Function in Patients After Arthroscopic Knee Surgery in Outpatient Rehabilitation
The goal of this clinical trial is to learn if a high intensity magnetic field is an effective way to treat quadriceps muscle atrophy after knee arthroscopic surgery in adult patients.
- Conditions
- Meniscus Injury, Meniscus Tear, Arthroscopic Knee Surgeries, ACL Injuries
- Trial name
- NCT06870825
- Testing
- High-intensity Magnetic Field Muscle Stimulation, Transcutaneous Neuromuscular Electrical Stimulation
- Where
- Lithuania
- Volunteers
- 150 people
- Sponsor
- Lithuanian University of Health Sciences
Meniscus Tear, Meniscus Lesion
PROPER Trial of Pain and Inflammation After Knee Arthroscopy
The purpose of this study is to determine if ceftriaxone administered postoperatively via intravenous injection reduces postoperative visual analog scale (VAS) pain scores and narcotic consumption in patients undergoing knee…
- Conditions
- Meniscus Tear, Meniscus Lesion, Cartilage Injury
- Trial name
- PROPER (NCT05149287)
- Testing
- Ceftriaxone
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Austin V Stone
Knee Osteoarthristis, Meniscus Injury
Hemi-tibial Plateau Osteotomy Combined With Arthroscopic Repair for Medial Meniscus Posterior Root Tears in Varus Knees
This is a single-center clinical trial started by the study team. The goal is to compare two surgeries for people who have a varus knee alignment and a tear at the back attachment of the medial meniscus.
- Trial name
- NCT07356674
- Testing
- Hemi-tibial plateau osteotomy combined with arthroscopic repair, High tibial osteotomy combined with arthroscopic repair
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Eighth Affiliated Hospital, Sun Yat-sen University
Meniscus Injury
Clinical Application Research of Combined Therapy in ERAS for Accelerated Orthopedic Rehabilitation
The double-blind method is adopted.Case selection Patients who underwent meniscus repair surgery under knee arthroscopy at Li Huili Hospital Affiliated to Ningbo University, the 906th Hospital of the People's Liberation Army…
- Trial name
- NCT07273032
- Testing
- Blank control group, Henggu Bone Injury Healing Agent Intervention Group, Lower limb rehabilitation training system intervention group
- Volunteers
- 120 people
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Meniscus Tear, Tibial
Diagnostic Value of Weight Bearing CT for Detecting Meniscal Tears
This observational study will compare the clinical value of weight-bearing CT arthrography (WBCTa) with that for MRI in evaluating meniscal and cartilage lesions of the knee joint.
- Trial name
- NCT04430829
- Testing
- Weight-Bearing CT arthrography, Knee MRI
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Kansas Medical Center
Meniscal Tear, Chondromalacia
The ChAMP (Chondral Lesions And Meniscus Procedures) Trial
The purpose of this randomized controlled trial is to determine the effectiveness of treating cartilage lesions found during knee arthroscopy.
- Trial name
- NCT01527201
- Testing
- Arthroscopic debridement
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- State University of New York at Buffalo
Chronic Meniscus Injury
Is a Knee Arthroscopy of Any Benefit for the Middleaged Patient With Meniscal Symptoms?
The purpose of this study is to determine whether a knee arthroscopy is effective in the treatment of middleaged patients with meniscal symptoms also receiving a standardised exercise program.
- Trial name
- NCT01288768
- Testing
- Knee arthroscopy
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- University Hospital, Linkoeping
Meniscal Extrusion, Meniscus Injury
Transtibial Pull Out Method Versus Suture Anchor Method for Meniscus Extrusion
The concept of meniscal extrusion has recently been recognized as an important pathological condition associated with meniscal dysfunction.
- Trial name
- NCT06906783
- Testing
- Transtibial Pull Out Method, Suture Anchor Method
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ataturk University
Meniscus Lesion
Effectiveness of Trephination With Platelet Rich Plasma or Placebo in a Primary Meniscal Tear Treatment
This study will compare meniscal healing augmented or without augmentation with platelet rich plasma in primary meniscal tear treatment (prolotherapy).
- Trial name
- Prolotherapy (NCT03066583)
- Testing
- trephination with platelet rich plasma
- Where
- Poland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education