Clinical trials: Meniere Disease
Meniere's Disease, Ménière's Vertigo
Study of Lamotrigine to Treat Ménière's Disease
This double-blinded study evaluates the frequency of vertigo attacks and the quality of life of patients diagnosed with Ménière's disease after being randomly assigned to take a placebo or lamotrigine.
- Conditions
- Meniere's Disease, Ménière's Vertigo, Vertigo, Intermittent, Vertigo, Aural
- Trial name
- NCT02158585
- Testing
- Lamotrigine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Dent Neuroscience Research Center
Vertigo, Meniere Disease
Effect of Stellate Ganglion Block on Meniere's Disease
Stellate ganglion block (SGB) has been the alternative treatment of Meniere's disease for years. However, objective evidence of the effect of SGB was still lack.
- Trial name
- NCT01574313
- Testing
- stellate ganglion block, 0.25mg, fludiazine, 25mg cephadol@ (diphenidol)
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Chi Mei Medical Hospital
Meniere Disease
Assessing the Efficacy of a Serotonin and Norepinephrine Reuptake Inhibitor for Improving Meniere's Disease Outcomes
As of yet, the cause of Meniere's disease is uncertain and there is no cure. Given the lack of high level evidence for treatments, we seek to perform a randomized, placebo-controlled, double-blind, crossover, pilot trial of…
- Trial name
- NCT04218123
- Testing
- Venlafaxine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Meniere Disease
Laser Acupuncture for Meniere Disease
Objective: To evaluate the effect of laser acupuncture for the patients Meniere disease. Methods: We enrolled 324 patients at Beijing Tongren Hospital.
- Trial name
- NCT06544434
- Testing
- Multiwave Locked System (MLS) laser (Mphi laser, ASA Srl, Vicenza, Italy), Betahistine Mesylate tablet
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Beijing Tongren Hospital
Meniere's Disease
Study of OTO-104 in Subjects With Unilateral Meniere's Disease
The purpose of this study is to evaluate the effectiveness of OTO-104 for the treatment of Meniere's disease.
- Trial name
- AVERTS-1 (NCT02612337)
- Testing
- OTO-104
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Otonomy, Inc.
Meniere's Disease
Sildenafil For Meniere's Disease
Meniere's disease affects a person's sense of balance. An attack can last 20 minutes to 2 hours or longer. Symptoms include rotational vertigo, hearing loss, tinnitus and a sensation of fullness in the affected ear and may be…
- Trial name
- NCT00145483
- Testing
- Sildenafil
- Where
- 4 sites in Australia
- Volunteers
- 163 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Meniere's Disease, Benign Paroxysmal Positional Vertigo
CAVA: Dizziness Trial
Clinical investigation of a medical device (CAVA) for recording eye movements. Patients suffering from diagnosed dizziness conditions will wear the device for 23 hours a day, for 30 days.
- Conditions
- Meniere's Disease, Benign Paroxysmal Positional Vertigo, Recurrent Vestibulopathy, Vestibular Migraine
- Trial name
- CAVA (NCT04026516)
- Testing
- CAVA Device
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Meniere Disease
A Study of a Mastoid Device in Subjects With Ménière's Disease
The purpose of this study is to investigate the efficacy of a mastoid treatment device in patients with active Ménière's disease that is not controlled by traditional medical management
- Trial name
- NCT03520322
- Testing
- Mastoid Oscillator, Control Device
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Rochester
Unilateral Acoustic Neuroma, Meniere's Disease
Cochlear Implantation After Labyrinthectomy or a Translabyrinthine Surgical Approach
The goal of this project is to determine whether subjects who have undergone labyrinthectomy or a translabyrinthine surgical approach as the treatment for vestibular schwannoma or Meniere's disease benefit from cochlear…
- Trial name
- NCT02309099
- Testing
- Cochlear Implant
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of North Carolina, Chapel Hill
Meniere's Disease
Effects of Endolymphatic Sac Drainage With Steroids for Meniere's Disease
Meniere's disease is a common inner ear disease with an incidence of 15-50 per 100,000 population. Since Meniere's disease is thought to be triggered by an immune insult to inner ear, we examined intra-endolymphatic sac…
- Trial name
- EDSS (NCT00500474)
- Testing
- endolymphatic sac drainage with steroids
- Where
- Japan
- Volunteers
- 197 people
- Sponsor
- Osaka University
Ménière
Treatment of Meniere's Disease With Migraine Medications
Meniere's disease (MD) is a chronic disease with a variety of fluctuating signs and symptoms, which include vertigo, hearing loss, tinnitus (ringing noise in the ear), aural pressure (feeling of ear fullness), and disequilibrium…
- Trial name
- NCT05582837
- Testing
- nortriptyline + topiramate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Irvine
Autoimmune Inner Ear Disease, Meniere's Disease
Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear Disease
A Phase II randomized, placebo controlled study design of anakinra (Kineret) in corticosteroid-resistant or intolerant Meniere's disease (CR-MD)and corticosteroid-resistant or intolerant autoimmune inner ear disease (CR-AIED)…
- Trial name
- NCT03587701
- Testing
- Anakinra 100Mg/0.67Ml Inj Syringe (Period 1), Anakinra 100Mg/0.67Ml Inj Syringe (Period 2)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Northwell Health
Vertigo
Effectiveness of Betaserc® (Betahistine Dihydrochloride) in Patients With Vestibular Vertigo in Routine Practice
The purposes of this international post-marketing observational program is to investigate effectiveness of betahistine dihydrochloride (Betaserc®) tablets and assess the course of vestibular vertigo after treatment…
- Trial name
- VIRTUOSO (NCT01759251)
- Where
- 24 sites in Russia, Ukraine
- Volunteers
- 309 people
- Sponsor
- Abbott
Meniere's Disease
Clinical Trial of Traditional Chinese Diaoshi Jifa Therapy of Meniere's Disease
The hypothesis of this study is that DiaoShi Jifa reduces the symptoms, such as dizziness in patients with Meniere's disease.
- Trial name
- TCDMD (NCT01454726)
- Testing
- Diaoshi Jifa therapy plus the Western medical treatment., drug
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Beijing Administration of Traditional Chinese Medicine Bureau
Autoimmune Inner Ear Disease
The Effects of Gevokizumab in Corticosteroid-resistant Subjects With Autoimmune Inner Ear Disease
The purpose of this study is to determine if gevokizumab therapy may be an alternate therapy in patients with steroid resistant Autoimmune Inner Ear Disease.
- Trial name
- NCT01950312
- Testing
- gevokizumab
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- XOMA (US) LLC
Ménière
Minimally Invasive Vestibular Neurectomy Versus Tenotomy of the Stapedius and Tensor Tympani Muscles in the Management of Patients With Unilateral Meniere's Disease
The distinctive symptoms of Meniere's disease (MD) include recurrent vertigo spells, fluctuating hearing loss, aural fullness and tinnitus.
- Trial name
- NCT04847700
- Testing
- Surgical treatment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Meniere's Disease
Efficacy of Local Overpressure Treatment for Meniere's Disease
The purpose of this study to date, is that no causal therapy for Meniere's disease has been discovered. Local overpressure treatment for Meniere's disease is a new treatment form that has been shown in animal and human…
- Trial name
- NCT00831688
- Testing
- Meniett(C) device by MedTronic
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Klinikum der Universitaet Muenchen, Grosshadern