Clinical trials: Meniere Disease
Intratympanic Steroid Injection, Idiopathic Sudden Sensorineural Hearing Loss
Comparing Topical Tetracaine Drops to Topical Focal Phenol for Local Anesthesia During Intratympanic Steroid Injection
Intratympanic steroid injections are an accepted treatment for Meniere's disease and idiopathic sudden sensorineural hearing loss. This treatment is typically performed using local topical anesthesia.
- Conditions
- Intratympanic Steroid Injection, Idiopathic Sudden Sensorineural Hearing Loss, Meniere Disease
- Trial name
- NCT04794842
- Testing
- Tetracaine 5% drops, Phenol 90% concentration
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Our Lady of the Lake Hospital
Meniere's Disease, Benign Paroxysmal Positional Vertigo
CAVA: Dizziness Trial
Clinical investigation of a medical device (CAVA) for recording eye movements. Patients suffering from diagnosed dizziness conditions will wear the device for 23 hours a day, for 30 days.
- Conditions
- Meniere's Disease, Benign Paroxysmal Positional Vertigo, Recurrent Vestibulopathy, Vestibular Migraine
- Trial name
- CAVA (NCT04026516)
- Testing
- CAVA Device
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Meniere Disease
Laser Acupuncture for Meniere Disease
Objective: To evaluate the effect of laser acupuncture for the patients Meniere disease. Methods: We enrolled 324 patients at Beijing Tongren Hospital.
- Trial name
- NCT06544434
- Testing
- Multiwave Locked System (MLS) laser (Mphi laser, ASA Srl, Vicenza, Italy), Betahistine Mesylate tablet
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Beijing Tongren Hospital
Meniere's Disease
Effects of Betaserc on Vestibular Compensation in Patients Suffering From Disabling Meniere's Disease and Having Undergone Vestibular Neurotomy
This study is to compare the effects of Betaserc 24mg and placebo on compensation of postural and locomotor deficits (static and dynamic posturography) after vestibular neurotomy in patients suffering from disabling Menière's…
- Trial name
- NCT00160238
- Testing
- Betahistine 24 mg bid (Betaserc)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Solvay Pharmaceuticals
Meniere Disease
Transcutaneous Auricular Vagus Nerve Stimulation for Meniere Disease
Objective: To evaluate the effect of Transcutaneous auricular vagus nerve stimulation for the patients Meniere disease. Methods: We enrolled 231 patients at Beijing TongRen Hospital.
- Trial name
- NCT06544590
- Testing
- taVNS, Betahistine Mesylate tablet
- Where
- China
- Volunteers
- 77 people
- Sponsor
- Beijing Tongren Hospital
Meniere Disease
Effects of Cervical Mobilization on Dizziness, Balance, and Joint Position Sense in Patients With Meniere's Disease
The study will employ a stratified randomization method. Patients presenting to the Afyonkarahisar Health Sciences University Health Application and Research Center, Ear, Nose, and Throat Outpatient Clinic, with a definitive…
- Trial name
- NCT07272473
- Testing
- Vestibular Rehabilitation + Cervical Mobilization, vestibular rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Abant Izzet Baysal University
Meniere's Disease
Magnetic Resonance Imaging Evaluation of Inner Ear Pathology Using Intra-Tympanic Contrast Agent
This is a pilot study of patients with clinical symptoms of Ménière's disease using injection of diluted magnetic resonance imaging (MRI) contrast agent into the ear to evaluate inner ear structures.
- Trial name
- NCT02080312
- Testing
- Magnevist (gadopentetate dimeglumine)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, San Diego
Ménière's Disease, Vestibular Migraine
The CAVA Multicentre Dizziness Trial
The CAVA trial is a diagnostic accuracy multicentre device trial which aims to quantify the extent to which the CAVA system can differentiate three common inner-ear causes of dizziness: Ménière's disease, vestibular migraine and…
- Conditions
- Ménière's Disease, Vestibular Migraine, Benign Paroxysmal Positional Vertigo (BPPV)
- Trial name
- CAVA 2 (NCT05984901)
- Testing
- The continuous ambulatory vestibular assessment (CAVA) system
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Meniere's Disease
Isobide Solution and Meniace Tablets Compared to Monotherapy With Meniace Tablets
A multicenter, randomized, open-label clinical study with a concurrent control group to assess the effectiveness and safety of combined therapy with Isobide solution and Meniace tablets compared to monotherapy with Meniace…
- Trial name
- NCT02718846
- Testing
- Meniace, Isobide
- Volunteers
- 220 people
- Sponsor
- Alvogen Korea
Meniere Disease, Allergic Rhinitis
Repurposed Use of Allergic Rhinitis and Allergic Asthma Drug to Reduce Vertigo and Hearing Loss in Meniere's Disease
The purpose of this study is to evaluate a previously FDA-approved medication that is known to help with allergy symptoms to see if it can decrease symptoms in patients with Meniere's Disease.
- Conditions
- Meniere Disease, Allergic Rhinitis, Vertigo
- Trial name
- NCT04815187
- Testing
- Montelukast
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- House Ear Institute
Meniere Disease, Psychosocial Problem
Comprehensive Evaluation in Patients With Meniere's Disease
The aim of our study is to determine the severity of the disease in people with Meniere's Disease; physical conditions such as balance, posture, pain, physical activity level, neck joint range of motion, proprioception; to…
- Conditions
- Meniere Disease, Psychosocial Problem, Physical Disability, Quality of Life
- Trial name
- NCT05844657
- Testing
- Case report form, Tinnitus disability scale, A feeling of fullness and/or pressure in the ear
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Meniere Disease
Transcutaneous Auricular Vagus Nerve Stimulation Treatment on Meniere Disease
Objective: To evaluate the effect of Transcutaneous auricular vagus nerve stimulation for the patients Meniere disease. Methods: We accrued 25 patients at Beijing TongRen Hospital.
- Trial name
- NCT04686695
- Testing
- taVNS
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Beijing Tongren Hospital
Meniere's Disease
SPI-1005 for the Treatment of Patients With Meniere's Disease
This study will evaluate the safety, efficacy, and Pharmacokinetics (PK) of two dose levels of SPI-1005 administered for 28 days compared to placebo in patients with Meniere's disease.
- Trial name
- NCT03325790
- Testing
- 200mg SPI-1005 BID, 400mg SPI-1005 BID
- Where
- 13 sites in United States
- Volunteers
- 149 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Meniere's Disease
Study of OTO-104 in Subjects With Unilateral Meniere's Disease
The purpose of this study is to evaluate the effectiveness of OTO-104 for the treatment of Meniere's disease.
- Trial name
- AVERTS-2 (NCT02717442)
- Testing
- OTO-104
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Otonomy, Inc.
Meniere's Disease
Evaluation of Inner Ear and Brain Structures With Contrast-enhanced MRI in Patients With Meniere's Disease
This prospective study aims to better characterize inner ear's perilymphatic structures with Magnetic Resonance Imaging using contrast media and delayed injection in patient's with Meniere's disease.
- Trial name
- PROSPER (NCT02530931)
- Testing
- Gadolinium
- Where
- France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Grenoble
Meniere's Disease, Ménière's Disease
SPI-1005 for the Treatment of Meniere's Disease (Open Label)
Study of the safety of open-label SPI-1005 400 mg BID treatment in adults with Meniere's Disease (MD) for 6 or 12 months to support chronic or chronic intermittent use.
- Trial name
- NCT06859788
- Testing
- Ebselen
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Meniere´s Disease
Efficacy and Safety of Isosorbide Oral Solution in Patients With Meniere's Disease
The purpose of this study is to evaluate the efficacy and safety of isosorbide oral solution compared with placebo in people with unilateral Meniere's disease.
- Trial name
- MD (NCT06765993)
- Testing
- Isosorbide oral solution
- Volunteers
- 234 people
- Sponsor
- Lunan Better Pharmaceutical Co., LTD.
Meniere Disease
Ventilation Tube Insertion for Unilateral Menière's Disease
The purpose of this trial is to assess the effects of transmyringeal ventilation tubes compared with sham-treatment which do not ventilate the middle ear, on the number of vertigo attacks lasting more than 20 minutes in…
- Trial name
- NCT04835688
- Testing
- Transmyringeal ventilation tube insertion
- Where
- Denmark
- Volunteers
- 104 people
- Sponsor
- Casper Grønlund Larsen
Meniere's Disease
Efficacy of Local Overpressure Treatment for Meniere's Disease
The purpose of this study to date, is that no causal therapy for Meniere's disease has been discovered. Local overpressure treatment for Meniere's disease is a new treatment form that has been shown in animal and human…
- Trial name
- NCT00831688
- Testing
- Meniett(C) device by MedTronic
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Klinikum der Universitaet Muenchen, Grosshadern
Ménière's Disease
Ménière's Disease Registry
Recent research has suggested that Ménière's disease may be a consequence of a number of individual conditions rather than developing from a single cause.
- Trial name
- MDR (NCT04438538)
- Where
- United Kingdom
- Volunteers
- 410 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust