Clinical trials: Meniere's Disease, active
Vertigo, Meniere's Disease
Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With Phenotypes
Aim of this work was to assess the role of polymorphisms belonging to genes involved in the regulation of ionic homeostasis in Caucasian patients with Ménière Disease (MD) and compare results with a cohort of patients affected by…
- Conditions
- Vertigo, Meniere's Disease, Vestibular Migraine
- Trial name
- Menière09 (NCT07518069)
- Testing
- a blood withdrawal will be obtained, blood withdrawal
- Where
- Italy
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Autoimmune Inner Ear Disease, Meniere's Disease
Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear Disease
A Phase II randomized, placebo controlled study design of anakinra (Kineret) in corticosteroid-resistant or intolerant Meniere's disease (CR-MD)and corticosteroid-resistant or intolerant autoimmune inner ear disease (CR-AIED)…
- Trial name
- NCT03587701
- Testing
- Anakinra 100Mg/0.67Ml Inj Syringe (Period 1), Anakinra 100Mg/0.67Ml Inj Syringe (Period 2)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Northwell Health
Meniere's Disease, Enlarged Vestibular Aqueduct Syndrome
Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets
Background: Disorders of hearing instability (HI) are poorly characterized and ineffectively treated. HI can cause fluctuations in hearing thresholds and speech understanding.
- Conditions
- Meniere's Disease, Enlarged Vestibular Aqueduct Syndrome, Autoimmune Inner Ear Disease
- Trial name
- NCT04806282
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Ménière
Treatment of Meniere's Disease With Migraine Medications
Meniere's disease (MD) is a chronic disease with a variety of fluctuating signs and symptoms, which include vertigo, hearing loss, tinnitus (ringing noise in the ear), aural pressure (feeling of ear fullness), and disequilibrium…
- Trial name
- NCT05582837
- Testing
- nortriptyline + topiramate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Irvine
Meniere´s Disease
Efficacy and Safety of Isosorbide Oral Solution in Patients With Meniere's Disease
The purpose of this study is to evaluate the efficacy and safety of isosorbide oral solution compared with placebo in people with unilateral Meniere's disease.
- Trial name
- MD (NCT06765993)
- Testing
- Isosorbide oral solution
- Volunteers
- 234 people
- Sponsor
- Lunan Better Pharmaceutical Co., LTD.
Meniere Disease, Allergic Rhinitis
Repurposed Use of Allergic Rhinitis and Allergic Asthma Drug to Reduce Vertigo and Hearing Loss in Meniere's Disease
The purpose of this study is to evaluate a previously FDA-approved medication that is known to help with allergy symptoms to see if it can decrease symptoms in patients with Meniere's Disease.
- Conditions
- Meniere Disease, Allergic Rhinitis, Vertigo
- Trial name
- NCT04815187
- Testing
- Montelukast
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- House Ear Institute
Meniere's Disease, Ménière's Disease
SPI-1005 for the Treatment of Meniere's Disease (Open Label)
Study of the safety of open-label SPI-1005 400 mg BID treatment in adults with Meniere's Disease (MD) for 6 or 12 months to support chronic or chronic intermittent use.
- Trial name
- NCT06859788
- Testing
- Ebselen
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Meniere Disease
The Effecttiveness of Intratympanic Methylprednisolon Injections Compared to Placebo in the Treatment of Vertigo Attacks in Meniere's Disease
Ménière's disease is an inner ear disorder in which patients suffer from attacks of vertigo, tinnitus and hearing loss. To date, it is unclear what the best treatment for this condition is.
- Trial name
- PREDMEN (NCT05851508)
- Testing
- Methylprednisolon
- Where
- Netherlands
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Vestibular Schwannoma, Meniere Disease
CI Following VS Removal or Labyrinthectomy
This study is a prospective, clinical study to determine if it is safe and effective to use a cochlear implant over time in individuals undergoing removal of a vestibular schwannoma (VS), benign tumor of the hearing and balance…
- Trial name
- NCT03795675
- Testing
- Cochlear Implant
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ohio State University