Clinical trials: Medico-economic Impact
Lymphoma
Remission Evaluation Before Intensified Treatment in Lymphoma: Impact of Positron Emission Tomography (PET) Using Fluorine-18-Floro-Deoxyglucose (FDG) in the Therapeutic Prescription. Medico-Economic Randomised Study
This randomised study aimed at evaluating the medical and economical impact of positron emission tomography (PET) using fluorine-18-fluoro-deoxyglucose (FDG) in the therapeutic prescription in patients with Hodgkin's lymphoma or…
- Trial name
- TEPELY (NCT00169598)
- Testing
- positron emission tomography
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Chronic Kidney Disease stage4, Kidney Diseases
Medico-economic Impacts of NeLLY Service for Not on Dialysis Severe Chronic Kidney Disease
This medico-economic research project (PRME) aim to analyse NeLLY service efficiency for not on dialysis severe chronic kidney disease (DFG < 30ml/mn) patients care.
- Trial name
- NCT03348839
- Testing
- NeLLY service
- Where
- 10 sites in France
- Volunteers
- 600 people
- Sponsor
- Calydial
Cerebral Palsy
Functional Effects and Impact on Motor Neuronal Activity of Early and Intensive Motrice (Hand and Arm Bimanual Intensive Therapy Including Lower Extremities: HABIT-ILE) Reeducation in Children With Pre-school Bilateral Cerebral Palsy
One of the urgent priorities in the field of pediatric neuro-rehabilitation is the development of efficient early motor interventions for children with cerebral palsy (CP).
- Trial name
- MOOV (NCT04362800)
- Testing
- MRI, Electro-Encephalography-High Density, 3D and EMG analysis
- Where
- 2 sites in France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Brest
Arthritis, Rheumatoid, Biological Therapy
Assessment of the Clinical and Medico-economic Impact of SinnoTest® in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is one of the main chronic inflammatory rheumatic diseases (RCI), with a prevalence of about 0.4% of the population.
- Trial name
- SINNO-RA (NCT04117165)
- Testing
- Biotherapy Prescription with SinnoTest® software, Patient Current Care
- Where
- 16 sites in France
- Sponsor
- University Hospital, Grenoble
Nonspecific Chronic Low Back Pain With Work Disability
Functional Restoration for Chronic Low Back Pain: Medico-economic Impact
The hypothesis is that functional restoration is not only effective in term of activity limitation, but also efficient, in regard to its impact on this criterion, the use of healthcare services, return to work and job retention…
- Trial name
- IMPREST (NCT07472374)
- Testing
- functional restoration, non-intensive rehabilitation
- Where
- France
- Volunteers
- 242 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer, Adequate Physical Condition
Impact of Nutritional Intervention in Women With Breast Cancer Under Adjuvant Chemotherapy
Breast cancer is the most common cancer in women. Weight gain in adulthood, overweight or obesity, physical inactivity and alcohol consumption are risk factors commonly associated with risk of breast cancer (mainly for…
- Trial name
- PASAPAS (NCT01331772)
- Testing
- Control arm, Intervention arm
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Leon Berard
Severe Neurological Disabilities
Medico-economic Impact Evaluation in Telemedecine Follow-up in Complement of a Mobile Team in Patients With Neurological Disabilities (HANDI@CCESS)
Access to care for people with traumatic or degenerative neurological disabilities is a current public health concern. New technological tools such as telemedicine can bring expertise to the place of life of people while…
- Trial name
- HANDI@CCESS (NCT03717974)
- Testing
- Telemedecine follow-up after an intervention at home of the mobile team, Mobile team follow-up after an intervention at home of the mobile team
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Pôle Saint Hélier
Breast Cancer, Surgery
Medico-economic Study of Three Strategies of Sentinel Lymph Node Analysis in Operable Breast Cancer
Breast carcinoma requires frequently an adjuvant therapy after surgical excision: in this way, one of the major criteria indicating the need of adjuvant chemotherapy is the diagnosis of a metastatic lymph-node invasion, mainly in…
- Trial name
- SAGE (NCT02056886)
- Testing
- SLN detection +/- complementary axillary lymphadenectomy
- Where
- 17 sites in France
- Volunteers
- 858 people
- Sponsor
- Institut Cancerologie de l'Ouest
Uterine Cervical Dysplasia
Comparison of Pelvic Lymphadenectomy Versus Isolated Sentinel Lymph Node Biopsy Procedure for Early Stages of Cervical Cancers : a Multicenter Study With Evaluation of Medico-economic Impacts
Patients with early cervical cancer are usually treated with radical hysterectomy + pelvic lymph-node dissection. The study randomizes patients in 2 arms.
- Trial name
- SENTICOL2 (NCT01639820)
- Testing
- identification of sentinel nodes + full pelvic lymph-node dissection, only identification of sentinel nodes (without pelvic lymph-node dissection)
- Where
- France
- Volunteers
- 267 people
- Sponsor
- Hospices Civils de Lyon
Exercise Therapy, Behavior and Behavior Mechanisms
Health-Enhancing Adapted Physical Activity Program at "Mon Stade"
Introduction: Regular practice of exercise or physical activity (PA) is a recognized intervention as a determinant of good health acquisition, maintenance, or recovery for a large number of chronic pathologies.
- Conditions
- Exercise Therapy, Behavior and Behavior Mechanisms, Adherence, Patient, Lifestyle, Sedentary
- Trial name
- SESAME (NCT04716322)
- Testing
- Adapted Physical Activity
- Where
- France
- Volunteers
- 2,024 people, healthy volunteers welcome
- Sponsor
- Mon Stade Sports Medicine Centre
Chronic Wounds
Impact médico-économique de la télésurveillance Des Plaies Chroniques Avec Pixacare
The healing of chronic wounds extends over several months and accounts for 3% of the healthcare budget. Care networks capable of managing chronic wounds are heterogeneous, insufficient, and poorly coordinated across the country.
- Trial name
- IMETP (NCT07528950)
- Testing
- Pixacare
- Volunteers
- 100 people
- Sponsor
- University Hospital, Lille
Suicide, Attempted, Relatives
IMTAP : Impact of the Suicide Attempt on the Nearly Entourage in Term of Traumatic Stress and Medico-economic Impact
With 11.000 deaths and 150.000 attempts each year in France, the suicide represents an important public health problem. For each death by suicide, one can count 6 "direct" bereaved people and 20 people in more indirect connection…
- Trial name
- IMTAP (NCT01213797)
- Where
- 12 sites in France
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Multiple Sclerosis
Disease Modifying Therapies Withdrawal in Inactive Secondary Progressive Multiple Sclerosis Patients Older Than 50 Years (STOP-I-SEP)
Further controlled and randomized prospective studies in Multiple sclerosis, analyzing the potential impact of treatment discontinuation on disability progression, focal disease activity and quality of life are needed.
- Trial name
- STOP-I-SEP (NCT03653273)
- Testing
- DMT withdrawal, DMT continuation
- Where
- 27 sites in France
- Volunteers
- 250 people
- Sponsor
- Rennes University Hospital
Dental Caries, Tooth Fractures
Comparison of Conventional and CAD/CAM Dental Restorations
Dental restorations (crowns, inlays or onlays) can be made conventionally or by CAD/CAM. The current literature is weak and does not separate the medical results of these two techniques.
- Conditions
- Dental Caries, Tooth Fractures, Tooth Resorption
- Trial name
- EVACFAOD (NCT02494427)
- Testing
- CAD/CAM manufactured fixed unitary dental prostheses, Conventionally manufactured unitary dental prostheses
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bipolar Disorder, Major Depressive Disorder
Evaluation of the Impact of the EDIT-B® Blood Test on the Health Status of Patients Presenting a Major Depressive Episode. Clinical Utility and Medico-Economic Aspects
Depression is one of the most common mental disorders, affecting nearly 10% of men and 20% of women worldwide. It is associated with a significant increase in mortality, mainly due to suicidal behavior.
- Trial name
- SEM EDIT-B (NCT06507787)
- Testing
- EDIT-B test, EDIT-B test (without giving result)
- Where
- 7 sites in France
- Volunteers
- 450 people
- Sponsor
- Alcediag
Primary Sjögren Syndrome, Small Fiber Neuropathy
Medico-economic and Quality of Life Impact of Sjogren-associated Small Fiber Neuropathy
BACKGROUND Sjögren's syndrome is an autoimmune disease whose prevalence is estimated between 200 and 500 patients per 100,000 persons in France (120 to 500,000 patients).
- Conditions
- Primary Sjögren Syndrome, Small Fiber Neuropathy, Quality of Life, Medico-economic Impact
- Trial name
- SFINESS-QoLEco (NCT03509064)
- Testing
- Collection sheet
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Metastatic Cancer
Medico-economic Evaluation Comparing the Impact of the New Fixed-dose Nivolumab Regimen With the Old mg/kg Regimen in the Management of Patients With Metastatic Cancer
Nivolumab is a selective monoclonal antibody that binds to the Programmed cell Death 1 (PD-1) receptor and causes reduced tumor growth. It is currently approved in France in many indications.
- Trial name
- IMEPOCA (NCT05380336)
- Where
- France
- Volunteers
- 40,000 people
- Sponsor
- Nantes University Hospital
Breast Cancer, Medico-economic Impact
Preoperative Magnetic Tracking in Breast Surgery in France: French Medical-economic Study.
MAGNETO is a French medico-economic study on preoperative localization in breast cancer surgery. The main objective is to conduct a cost-consequence analysis comparing magnetic clip localization with the use of metallic wires for…
- Conditions
- Breast Cancer, Medico-economic Impact, Breast Cancer Surgery
- Trial name
- MAGNETO (NCT06906601)
- Testing
- magnetic clip localization, metallic wire localization., Breast cancer surgery
- Where
- 7 sites in France
- Volunteers
- 772 people
- Sponsor
- Centre Leon Berard
Low Risk of Preterm Delivery
Medico-economic Impact of Screening Atopobium Vaginae and Gardnerella Vaginalis in Molecular Biology by "Point-of-care" During Pregnancy
Infection is the principal cause of preterm births. Most (90%) women with preterm deliveries have no abnormal history. It is widely agreed that preterm delivery is often associated with bacterial vaginosis.
- Trial name
- AuTop (NCT02288832)
- Testing
- -self-collected vaginal samples, zithromax, usual practices
- Where
- 2 sites in France
- Volunteers
- 6,800 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Suicide, Attempted
Effectiveness of a Case Management Algorithm: ALGOS After a Suicide Attempt
The suicidal behaviors are phenomena eminently multifactorial. It is thus always difficult to define univocal strategies of prevention of suicide repetition, during the emergency stay, i.e. almost in general population.
- Trial name
- ALGOS (NCT01123174)
- Testing
- ALGOS algorithm of case management
- Where
- 23 sites in France
- Volunteers
- 1,040 people
- Sponsor
- University Hospital, Lille