Clinical trials: Medication Systems
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Resistant Hypertension, Medication Adherence
Heart Rate Variability and Medication Adherence in Resistant Hypertension
This single-center, cross-sectional observational study examines the relationship between adherence to antihypertensive therapy - verified objectively by therapeutic drug monitoring (TDM) - and heart rate variability (HRV) in…
- Conditions
- Resistant Hypertension, Medication Adherence, Autonomic Nervous System
- Trial name
- HRV-HYP-1 (NCT07707583)
- Testing
- Heart rate variability recording (Polar H10) ·, Therapeutic drug monitoring (antihypertensive drug levels), Questionnaires (MARS-CZ, PHQ-9, SF-36, IPAQ)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Myasthenia Gravis (MG), Myasthenia Gravis, Generalized
AXIS MG Patient Registry
The goal of the AXIS Autoimmune Neurology Registry is to learn about the experiences of adults living with autoimmune neurological disorders, starting with myasthenia gravis (MG), over time.
- Conditions
- Myasthenia Gravis (MG), Myasthenia Gravis, Generalized, Myasthenia Gravis, Ocular, Myasthenia Gravis Crisis
- Trial name
- AXIS (NCT07761026)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Autoimmune Neurology Alliance
Palliative Care, Terminal Care
Appropriate Medication Use in Dutch Terminal Care
The AMUSE trial is a multicentre stepped-wedge cluster randomized controlled trial where medication optimization of patients with a life expectancy of less than three months is investigated by using CDSS-OPTIMED (a personalized…
- Conditions
- Palliative Care, Terminal Care, Medication Therapy Management, Clinical Decision Support System (CDSS)
- Trial name
- AMUSE (NCT05351281)
- Testing
- CDSS-OPTIMED
- Where
- 7 sites in Netherlands
- Volunteers
- 250 people
- Sponsor
- Prof.dr Carin (C.C.D.) van der Rijt
Medication Systems, Quality Improvement
Use and Opinions of Care Home Medicines Audit Tools
To describe the barriers and facilitators experienced by residents, health and social care staff, commissioners and regulators when managing medicines within care homes.
- Trial name
- NCT05133700
- Testing
- Interview or focus group discussion, Review of submitted medicines audit tools
- Where
- United Kingdom
- Volunteers
- 152 people
- Sponsor
- University of Central Lancashire
Multimorbidity, Polypharmacy
MultiPAP Plus: Improving Prescription in Primary Care Patients With Multimorbidity and Polypharmacy
This study assesses the effectiveness of a complex intervention in young-old patients with multimorbidity and polypharmacy aimed at improving physician drug prescription in primary care, measured by hospitalization-mortality at…
- Conditions
- Multimorbidity, Polypharmacy, Comorbidities and Coexisting Conditions, Clinical Decision-Support Systems
- Trial name
- MultiPAP Plus (NCT04147130)
- Testing
- MultiPAP Plus, Usual care
- Where
- 3 sites in Spain
- Volunteers
- 1,162 people
- Sponsor
- Instituto Aragones de Ciencias de la Salud
Endocrine Disorder, Deficiency
Endocrinological Profile in Patients With Medication-overuse Headache Before and After Withdrawal Therapy
The project will be conducted to investigate the hormonal homeostasis in men and women, with a special emphasis on sex hormones in men and AMH level in women, before and after withdrawal of the overused analgesics among MOH…
- Conditions
- Endocrine Disorder, Deficiency, Medication Overuse Headache, Migraine
- Trial name
- ENDOMOH (NCT04090333)
- Testing
- Standard withdrawal therapy
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Danish Headache Center
Medication Systems, Breast Feeding
The Feasibility of Drug Delivery to Infants During Breastfeeding
Parents commonly find giving medicines to babies, using oral syringes or spoons, difficult and emotionally stressful. In developing countries, additional stress arises due to hygiene difficulties and the lack of clean water.
- Conditions
- Medication Systems, Breast Feeding, Milk, Human, Infant, Newborn
- Trial name
- FEDD (NCT03799367)
- Testing
- Drug delivery during breastfeeding
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Medication Errors, Medical Records Systems, Computerized
Improving Pediatric Safety and Quality With Health Care Information Technology
This study includes four projects aimed to improve the quality and safety of pediatric care through the implementation of four clinical decision support services in the electronic health record (EHR).
- Conditions
- Medication Errors, Medical Records Systems, Computerized, Patient Safety, Quality Improvement
- Trial name
- NCT00134823
- Testing
- weight based dosing decision support
- Where
- United States
- Volunteers
- 5,420 people
- Sponsor
- Massachusetts General Hospital
Drugs, Non-Prescription, Medication Systems
Over-the-Counter Medication Usage
There are several benefits of over-the-counter medications, yet there is little research evaluating how to increase patient compliance when a health care provider suggests an over-the-counter (OTC) medication.
- Trial name
- NCT00439348
- Testing
- Verbal advice, Prescription
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- AdventHealth