Clinical trials: Medically Complex
Heart Failure
Development of Scalable New Model(s) Focused on Care Co-ordination and Care Provision for Medically Complex, Co-morbid Chronic Disease Patient Segments Focusing on Heart Failure
The goal is to define a set of clinical pathways for heart failure patients, reflecting the period from prior to admission to the post-discharge period following hospitalisation, under the current system that exists at the two…
- Trial name
- NCT02921607
- Testing
- Observational group
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Medically Complex Infants
Effects of Medical Complexity Using GMA on Lurie Children's In- and Outpatients
The purpose of this study is to research a new type of test for cerebral palsy that can be performed earlier, at 10-15 weeks of age (after the due date for premature infants).
- Trial name
- CIMA (NCT01659710)
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Raye Ann deRegnier
Diabetes Mellitus, Hypertension
Effectiveness of Home-Based Health Messaging for Patients With Hypertension and Diabetes
Patients treated at Veterans Affairs (VA) medical centers are older and have multiple chronic conditions. Two of the most common conditions in the VA population are hypertension (HTN) and Type 2 diabetes (DM).
- Trial name
- NCT00119054
- Testing
- In Home Health Messaging Device
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- US Department of Veterans Affairs
Multimorbidity, Cognitive Impairments
Video-Enhanced Care Management for Medically Complex Veterans
The purpose of this study is to examine the feasibility and acceptability of a 12-week care management program for medically complex Veterans with cognitive impairment, delivered via telephone or videoconferencing.
- Trial name
- NCT02962687
- Testing
- Care management via videoconference, Care management via telephone calls
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
Health Services, Comorbidity
Ambulatory ICU Study for Medically and Socially Complex Patients
This is a prospective randomized wait-list control study to determine whether a stand-alone, co-located team of physician, mental health behaviorist, and care coordinators with decreased panel size (aka "intensive primary care")…
- Conditions
- Health Services, Comorbidity, Primary Health Care
- Trial name
- SUMMIT (NCT03224858)
- Testing
- SUMMIT intervention, Enhanced usual care
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Opioid Dependence, Substance Abuse Disorders
The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Disorder Seen In Primary Care
The goal of this pilot clinical trial is to learn if a community informed designed program of addiction counseling with coordinated community peer navigator for people with Opioid Use Disorder (OUD) and other medical conditions…
- Conditions
- Opioid Dependence, Substance Abuse Disorders, Complex Medical Patients, Primary Care Patients With Chronic Conditions
- Trial name
- MOUD+ (NCT06837662)
- Testing
- MOUD "Plus" Intervention (treatment as usual + coordinated counseling and referral to community based peer), Treatment As Usual (primary care with low threshold MOUD prescribing)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Oregon Health and Science University
Medication Errors and Other Product Use Errors and Issues
Meds@HOME App to Support Medication Safety
This study determines whether the mHealth intervention, Meds@HOME, helps caregivers improve medication administration to Children with Medical Complexity (CMC) who use high-risk medications.
- Trial name
- NCT05816590
- Testing
- Med@HOME Mobile App
- Where
- United States
- Volunteers
- 336 people
- Sponsor
- University of Wisconsin, Madison
Aging, Functional Recovery
Advancing Rehabilitation Paradigms for Older Adults in Skilled Nursing Facilities
This cluster randomized clinical trial seeks to provide large-scale, foundational evidence that high-intensity rehabilitation is effective and can be systematically implemented to improve functional outcomes for patients admitted…
- Conditions
- Aging, Functional Recovery, Skilled Nursing Facility, Medically Complex
- Trial name
- NCT05492240
- Testing
- i-STRONGER, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 4,383 people
- Sponsor
- University of Colorado, Denver
Pediatrics, Medically Complex
Parental Adherence of a Mobile Application
This is a single-site, stratified grouping parallel- randomized control trial design comparing 30-day all-cause readmission rates and parent experience with two groups of pediatric participants.
- Conditions
- Pediatrics, Medically Complex, Children With Medical Complexity (CMC), Nursing
- Trial name
- PARAMETER (NCT06672042)
- Testing
- CHAMP App
- Where
- United States
- Sponsor
- Children's Mercy Hospital Kansas City
Infant and Young Child Feeding
Standardized Application of Feeding Evaluations Using SMART Tool
Premature and medically complex infants have delayed development of oral feeding skills, leading to prolonged hospitalization, costs, and family stress.
- Trial name
- SAFEST (NCT07136610)
- Testing
- SMART Tool
- Where
- 14 sites in United States
- Volunteers
- 3,500 people
- Sponsor
- Wake Forest University Health Sciences
Neonates
NICU-TECH RM9L-RS Probe ME Feasibility Study
Use of a new ultrasound device designed for babies to look at the catheters in veins and arteries as well as the blood vessel itself.
- Trial name
- NCT01181596
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- GE Healthcare
Substance Addiction
A Comprehensive Peer Mentor-based Disease Management Program for Medically Complex Substance Users
Substance-using adults are admitted to hospital for medical complication from their drug and alcohol use at very high rates; yet, their care is often defined by low rates of referral to addiction treatment programs and…
- Trial name
- NCT00993395
- Testing
- peer mentor-based disease management
- Where
- United States
- Sponsor
- Johns Hopkins University
Multimorbidity, Physical Deconditioning
Engaging Medically Complex Veterans in Tele-Rehabilitation Using a Biobehavioral Approach
The aims of this study are to determine the feasibility and acceptability of a multicomponent telerehabilitation program for medically complex older Veterans and to preliminarily assess participant outcomes (physical activity…
- Trial name
- NCT04942613
- Testing
- Motivational Interviewing Techniques, Physical Therapy Interventions, Education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Aging, Functional Recovery
Supplemental Mobility
This pilot study will evaluate the feasibility of a supplemental mobility intervention, the Safe Transfers And Mobility Program (STAMP).
- Conditions
- Aging, Functional Recovery, Skilled Nursing Facility, Medically Complex
- Trial name
- NCT07872384
- Testing
- High Intensity Rehabilitation, Safe Transfers and Mobility Program, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 192 people
- Sponsor
- University of Colorado, Denver
Substance-related Disorder
A Comprehensive Disease Management Program for Medically-Complex Substance Users
Disease management (DM) programs are being increasingly utilized by health plans to coordinate care, improve quality of care, and control costs in chronically ill individuals.
- Trial name
- NCT00865956
- Testing
- Contingency Management, Case management
- Where
- United States
- Sponsor
- Johns Hopkins University
Overweight, Obese
Physical Activity and Health Outcomes
Obesity is common in adults with complex medical problems with ensuing complications afterwards. Obese patients suffer higher mortality and impaired functional status often as a result of their obesity.
- Trial name
- PAHO (NCT01833507)
- Testing
- Self-Exercise, Usual Care
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cardiovascular Risk
Self Management and Reminders With Technology: SMART Appraisal of an Integrated Personal Health Record (PHR)
This project seeks to improve health care outcomes in complex patients with cardiovascular disease (CVD) or who are at high risk for developing CVD by promoting patient self-management.
- Trial name
- SMART PHR (NCT01078532)
- Testing
- SMART PHR, usual care
- Where
- United States
- Volunteers
- 1,815 people
- Sponsor
- University of Pittsburgh
Medically Complex Children, Care Coordination
Improving Care for Children With Complex Needs
Seattle Children's Hospital (SCH), in collaboration with several health plans and Washington State Department of Social and Health Services developed the Comprehensive Case Management (CCM) program with the goal to reduce costs…
- Conditions
- Medically Complex Children, Care Coordination, Case Manager, Care Manager
- Trial name
- I3CN (NCT01587105)
- Testing
- Comprehensive Case Management Service
- Where
- United States
- Volunteers
- 331 people
- Sponsor
- Seattle Children's Hospital
Quality of Life, Chronic Disease
Comprehensive Care of Children With Medical Complexity
Under the auspice of 'Specially for Children and with funding from the Seton Healthcare Family, Children's Comprehensive Care (CCC) in Austin, Texas, has developed a coordinated and integrated model of care for children with…
- Conditions
- Quality of Life, Chronic Disease, Chronic Illness
- Trial name
- NCT01834456
- Testing
- Med Complex Children Intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Seton Healthcare Family
Rheumatoid Arthritis, Diabetes
Effects of a Multi-Faceted Psychiatric Intervention Targeted at the Complex Medically Ill: a Randomized Controlled Trial
Background: somatic patients with psychiatric co-morbidities are a major challenge for the health care system. This study evaluated a psychiatric intervention targeted at the complex medically ill identified by means of the…
- Trial name
- NCT00385528
- Testing
- Multi-faceted psychiatric intervention
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University of Lausanne Hospitals