Clinical trials: Medical Termination of Pregnancy
Abortion Early
Very Early Medical Abortion
The research question begin addressed by this study is "Is Very Early Medical Abortion (VEMA - before a pregnancy is visible on ultrasound scan) as effective as medical abortion when performed later and an intrauterine pregnancy…
- Trial name
- VEMASCOT (NCT03989869)
- Testing
- Immediate treatment
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Completion of Medical Abortion
Use of Low Sensitivity Pregnancy Test for Self-assessment of Medical Abortion
The purpose of the study is to design a self-assessment package that could be the preferred option to a follow-up visit at the clinic by the majority of women having early medical abortion.
- Trial name
- m-Assist+ (NCT02231619)
- Testing
- Baseline verbal instruction on LSUPT
- Where
- South Africa
- Volunteers
- 525 people
- Sponsor
- University of Cape Town
Miscarriage
Sublingual Versus Vaginal Misoprostol In Medical Treatment of Second Trimestric Missed Miscarriage
The aim of this work is to compare the effectiveness of vaginal versus sub-lingual misoprostol for medical treatment of the second trimester missed miscarriage
- Trial name
- NCT05088707
- Testing
- sublingual misoprostol, vaginal misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
Medical Abortion
The Acceptability and Feasibility of an Alternative to Routine Follow-up Visit After Medical Abortion in Vietnam
This trial will compare the efficacy and acceptability of post-medical abortion follow-up by assigning women to either 1) alternative follow-up via routine semi-quantitative pregnancy test and a self-administered follow-up…
- Trial name
- NCT01150422
- Testing
- Alternative follow-up
- Where
- 4 sites in Vietnam
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Outpatient Medical Abortion With Mifepristone and Misoprostol Through 77 Days of Gestation
To demonstrate non-inferiority of the efficacy of 200 mg mifepristone followed in 24 to 48 hours by 800 µg buccal misoprostol in outpatient medical abortion services among women 71-77 days' compared to women 64-70 days' LMP.
- Trial name
- XXGA (NCT02314754)
- Testing
- Mifepristone followed by misoprostol 24-48 hours later
- Where
- 8 sites in United States, Azerbaijan and 3 more
- Volunteers
- 719 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion Induced Complicated, Abortion
Second Trimester Abortion With Letrozole and Misoprostol Compared to Misoprostol Alone
Termination of Second trimester Abortion with Letrozole and Misoprostol Compared to Misoprostol Alone
- Trial name
- NCT07767435
- Testing
- · Misoprostol + letrozole, misoprostol alone
- Volunteers
- 80 people
- Sponsor
- Sohag University
Pregnancy
Evaluation of Telemedicine Medical Abortion Service in Ecuador
This research seeks to demonstrate that a telemedicine model for the provision of legal abortion services in Ecuador is safe, feasible and acceptable to users requesting a medication abortion and who are less than 12 weeks…
- Trial name
- NCT06270056
- Testing
- Misoprostol
- Where
- 3 sites in Ecuador
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Contraception
Immediate Versus Delayed Insertion of the Copper Intrauterine Device (IUD) After Medication Abortion
After medication abortion, women may quickly become pregnant again and therefore need an effective birth control method right away. Intrauterine devices (IUDs) are very effective for preventing pregnancy.
- Trial name
- NCT00737178
- Testing
- CuT380A
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Columbia University
Miscarriage
Vaginal Misoprostol In Medical Treatment of First Trimester Missed Miscarriage
Efficacy of vaginal misoprostol 600 Mg versus 800 Mg in termination of the first trimester missed abortion were assist
- Trial name
- NCT05094375
- Testing
- Vaginal Misoprostol 600 mcg, Vaginal Misoprostol 800 mcg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- hany farouk
Abortion, Induced
Mifepristone Plus Misoprostol Versus Misoprostol Alone for 2nd Trimester Abortion (14 - 21 Weeks Last Menstrual Period (LMP))
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00969982
- Testing
- mifepristone+misoprostol
- Where
- 2 sites in Moldova, Tunisia
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion in First Trimester
Telemedicine for First Trimester Abortion in South Africa
The study aim to determine if medical abortion facilitated by a physician online (s.c. telemedicine), combined with a simplified physical exam, is equally effective, safe and acceptable to women in South Africa as standard…
- Trial name
- NCT04336358
- Testing
- Telemedicine
- Where
- 4 sites in South Africa
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Termination of Pregnancy
Uptake and Acceptability of Home-use of Mifepristone for Medical Abortion
The primary aim of this study is to assess the acceptability of home-use mifepristone for termination of pregnancy among women who choose it and their providers.
- Trial name
- NCT00994734
- Testing
- Mifepristone
- Where
- 7 sites in United States, Moldova and 1 more
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Infertility, Intellectual Disability
Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities
Chromosomal aberrations are major causes of developmental disorders (Intellectual disability (ID), multiple congenital anomalies (MCA), autism spectrum disorders (ASD)) as well as reproductive disorders (RD) in particular…
- Conditions
- Infertility, Intellectual Disability, Malformation, Miscarriage
- Trial name
- CHROMAPS (NCT05290051)
- Testing
- Optical Genome Mapping (Bionano®), Longread sequencing (Nanopore®)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Medical; Abortion, Fetus
Fetal Fibronectin as a Predictor of Successful Induction of Mid-trimester Abortion
Fetal Fibronectin as a Predictor of Successful Induction of Mid-trimester abortion.
- Trial name
- NCT02694198
- Testing
- fetal fibronectin measurement
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Contraception
Study of Immediate Start of Progestin Contraceptives in Medical Abortion
This study will compare immediate to post-abortion start of two progestin-based contraceptives (DMPA and etonorgestrel implants) among women having first trimester medical abortion who wish to use that method for post-abortion…
- Trial name
- Quickstart (NCT01902485)
- Testing
- Timing of Contraceptive Initiation in Medical Abortion
- Where
- 8 sites in United States, Mexico
- Volunteers
- 937 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion, Pain
Cannabinoids for Pain Control During Medical Abortion
The objective of this study is to determine if a synthetic cannabis derivative, dronabinol, in addition to ibuprofen, decreases maximum pain scores compared to ibuprofen and placebo in women undergoing medical abortion.
- Trial name
- NCT03604341
- Testing
- Dronabinol 5mg Cap
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Oregon Health and Science University
Medical Abortion
Self-Assessment of Medical Abortion Outcome Using Serial Multi-level Pregnancy Tests
This study aims to investigate the effectiveness and acceptability of the multi-level pregnancy test for self-assessment of abortion outcomes, without a routine provider contact.
- Trial name
- NCT02570204
- Testing
- Self-assessment
- Where
- 3 sites in United States
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Missed Miscarriage
Mifepristone and Misoprostol Versus Misoprostol Alone in the Medical Management of Missed Miscarriage
Miscarriage is the most common complication of pregnancy. As many as 15-25% of pregnancies end in miscarriage, and the number of miscarriages in England is estimated to be approximately 125,000 per year.
- Trial name
- MifeMiso (NCT03065660)
- Testing
- Mifepristone, Oral, 200 Mg
- Where
- 28 sites in United Kingdom
- Volunteers
- 711 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Early Pregnancy Failure
Comparing Two Medical Treatments for Early Pregnancy Failure.
This study aims to compare whether a combination of two drugs (Mifepristone and misoprostol) are superior compared to using only one of these drugs (Misoprostol) as medical treatment for a miscarriage.
- Trial name
- Triple M (NCT03212352)
- Testing
- Mifepristone, Misoprostol
- Where
- 13 sites in Netherlands
- Volunteers
- 342 people
- Sponsor
- Radboud University Medical Center
Miscarriage
Sublingual Misoprostol In Medical Treatment of First Trimester Missed Miscarriage
The aim of this work is to compare the effectiveness of sublingual misoprostol 400 mcg versus 800 mcg for medical treatment of the first trimester missed miscarriage.
- Trial name
- NCT05103098
- Testing
- misoprostol 400 mcg, misoprostol 800 mcg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- hany farouk