Clinical trials: Mechanical Power
Mechanical Power, Acute Respiratory Failure
Mechanical Power During Pressure Controlled Versus Volume-Controlled Ventilation in Acute Respiratory Failure
This prospective observational cohort study aims to compare mechanical power between pressure-controlled ventilation (PCV) and volume-controlled ventilation (VCV) in critically ill adult patients receiving invasive mechanical…
- Trial name
- MP-PCV-VCV (NCT07834970)
- Where
- Egypt
- Volunteers
- 186 people
- Sponsor
- Assiut University
Patient Transport, Respiratory Failure
HERMES: International Survey and Portable External Power Evaluation During Respiratory Support Transport
The HERMES Phase I-II study was a two-phase observational investigation designed to characterize contemporary practices and safety-related challenges associated with the transport of patients requiring advanced respiratory…
- Conditions
- Patient Transport, Respiratory Failure, Noninvasive Ventilation, High-Flow Nasal Oxygen
- Trial name
- HERMES (NCT07807189)
- Testing
- Portable External Power Supply
- Where
- 20 sites in United States, Chile and 12 more
- Volunteers
- 246 people
- Sponsor
- Medipol University
Acute Respiratory Distress Syndrome (ARDS), s100b
A Study of the Determinants of Neurological Outcomes in Patients With Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is characterized by pathological pulmonary edema caused by direct or indirect damage to the alveolar-capillary membrane.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), s100b, Mechanical Power, Ventilator Induced Lung Injury
- Trial name
- NEURDS (NCT07629973)
- Testing
- Blood test scores calculations
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Intra Abdominal Pressure, Mechanical Power
Relationship Between Mechanical Ventilator's Modes , Intra-Abdominal Pressure, Mechanical Power and Gastric Tube Tolerance Among Mechanically Ventilated Patients.
The study aims to: Explore the relationship between MV modes on the IA, MP and GT tolerance among mechanically ventilated patients.
- Trial name
- MV and IAP (NCT07687303)
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Heba.Attia@nur.dmu.edu.eg
Mechanical Power
Comparison of Laryngeal Mask Airway and Endotracheal Intubation on Mechanical Power in Pediatric Patients
This prospective observational study aims to compare two commonly used airway management methods-Laryngeal Mask Airway (LMA) and Endotracheal Intubation (ETT)-in pediatric patients undergoing elective surgery under general…
- Trial name
- LMA-MP (NCT07252674)
- Testing
- Laryngeal Mask Airway (LMA)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Konya City Hospital
Cardiac Surgery, Mechanical Power
Individualized PEEP and Pulmonary Complications in On-Pump CABG
Postoperative pulmonary complications (PPCs) are an important cause of morbidity and mortality after major surgery and are frequently observed in cardiac surgery patients undergoing cardiopulmonary bypass (CPB).
- Conditions
- Cardiac Surgery, Mechanical Power, Postoperative Pulmonary Complications (PPCs)
- Trial name
- NCT07623109
- Testing
- Driving pressure-based personalized PEEP strategy, Conventional lung protective mechanical ventilation strategy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital
Weaning Mechanical Ventilation, Mechanical Power
Evaluation of Mechanical Power and Ventilator Parameters to Predict Weaning Success in the Intensive Care Unit
The goal of this prospective observational study is to evaluate whether ventilator-based respiratory parameters can predict weaning success in adult intensive care unit (ICU) patients who are mechanically ventilated.
- Conditions
- Weaning Mechanical Ventilation, Mechanical Power, Negative Inspiratory Force, Airway Occlusion Pressure
- Trial name
- NCT07268989
- Testing
- Mechanical power
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Anıl Berkay Balıtatlı
Mechanical Ventilation, Sedation
Inhalational Sedation and Mechanical Power
Analgosedation is usually given to critically ill patients admitted in ICU. Fentanyl is the most common agent used for this purpose. For sedative agent, midazolam and propofol are commonly administered.
- Conditions
- Mechanical Ventilation, Sedation, Mechanical Power, Lung Injury
- Trial name
- NCT05559970
- Testing
- Inhalational sedation, Convention sedation
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Postoperative Pulmonary Complication, Mechanical Power
Postoperative Pulmonary Complications in Adult PNL Patients
The aim of this study is to investigate the effect of different surgical positions (supine/prone) on lung mechanical power (MP) and its relationship with postoperative pulmonary complications in patients planned to percutaneous…
- Trial name
- NCT06462976
- Testing
- mechanical power calculation
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- TC Erciyes University
Mechanical Power, Postoperative Pulmonary Complications (PPCs)
EIT vs Dynamic Compliance Guided PEEP Titration During Laparoscopic Gynecological Surgery
The goal of this randomized controlled clinical trial is to compare the pulmonary protective effects of two different positive end-expiratory pressure (PEEP) titrating methods in patients with non-injured lungs undergoing…
- Conditions
- Mechanical Power, Postoperative Pulmonary Complications (PPCs), Oxygenation
- Trial name
- TITRANT (NCT07170514)
- Testing
- EIT-guided PEEP titration, Cdyn-guided PEEP titration
- Where
- 3 sites in Hungary
- Volunteers
- 200 people
- Sponsor
- Pest County Flór Ferenc Hospital
Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications
Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications
The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Driving Pressure (ΔP), in…
- Conditions
- Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications, Postoperative Respiratory Failure, Postoperative Bronchospasm
- Trial name
- NCT07186933
- Testing
- PEEP titration for Minimum Driving Pressure, Lung Protective Ventilation
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University General Hospital of Patras
Mechanical Ventilation, Mechanical Power
Investigation of the Optimum PEEP Mechanical Power Relationship
The aim of this study is to compare the effects of standard and optimum positive end expiratory pressures on mechanical power during laparoscopic surgeries.
- Conditions
- Mechanical Ventilation, Mechanical Power, Optimum PEEP, Laparoscopic Abdominal Surgery
- Trial name
- NCT06625099
- Testing
- Mechanical Ventilation (MV) with Low PEEP, Mechanical Ventilation (MV) with Optimum PEEP
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Kocaeli City Hospital
COVID - 19, Thoracic Anesthesia
COVID-19 Infection and Thoracic Anesthesia?
SARS-CoV-2 has infected more than 776 million people worldwide, raising concerns about its impact on patients with lung cancer, the most common cancer in men and the second most common cancer in women.
- Conditions
- COVID - 19, Thoracic Anesthesia, Mechanical Power
- Trial name
- NCT07118917
- Testing
- Prehabilitation, No postponement
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara University
Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation
Effect of Transpulmonary MP on Prognosis of Patients With Severe ARDS Treated With VV-ECMO
Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a salvage treatment for severe acute respiratory distress syndrome (ARDS).
- Conditions
- Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation, Mechanical Power, Transpulmonary Mechanical Power
- Trial name
- NCT06062212
- Testing
- Transpulmonary pressure
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Chao Yang Hospital
Acute Hypoxemic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
EIT-Guided Ventilator Settings in AHRF
This exploratory study aims to investigate the effect of Electrical Impedance Tomography (EIT)-guided ventilator settings on mechanical power in patients with acute hypoxemic respiratory failure (AHRF), including both ARDS and…
- Conditions
- Acute Hypoxemic Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS), Mechanical Power, Ventilator Induced Lung Injury
- Trial name
- NCT06936618
- Testing
- Electrical Impedance Tomography (EIT), Enlight 2100
- Where
- Thailand
- Volunteers
- 17 people
- Sponsor
- Mahidol University
COPD (Chronic Obstructive Pulmonary Disease), ARDS (Acute Respiratory Distress Syndrome)
Can Total Mechanical Power Be a Determinant of Weaning Failure in Chronic Obstructive Pulmonary Disease (COPD)?
A Comparison of Ventilator Parameters (TV, DP, Total Mechanical Power, etc.) Between Successfully and unsuccessfully Weaned Patients with COPD Undergoing Mechanical Ventilation Due to Respiratory Failure, and Diagnosed with…
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), ARDS (Acute Respiratory Distress Syndrome), Mechanical Power, Pneumonia
- Trial name
- NCT06751654
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Mechanical Power, Alveolar Recruitment Maneuvers
The Role of Periodic Alveolar Recruitment Maneuvers in Intraoperative Protective Ventilation
The goal of this clinical trial is to compare three open-lung strategies on respiratory function and lung injury in protective ventilation for laparoscopic anterior resection.
- Conditions
- Mechanical Power, Alveolar Recruitment Maneuvers, Protective Ventilation, Postoperative Pulmonary Complications
- Trial name
- REMAIN-2 (NCT05962125)
- Testing
- periodic alveolar recruitment maneuvers, positive end-expiratory pressure
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Mechanical Power
Mechanical Power As a Predictor for Weaning in Chronic Obstructive Pulmonary Disease Patients :Prospective Cohort Study.
The primary objective is to evaluate the mechanical power as a predictor of weaning of mechanical ventilation in COPD patients hospitalized in the respiratory intensive care unit of Assiut University Hospital The secondary…
- Trial name
- NCT06493929
- Testing
- Chest ultrasound, Calculation of Mechanical Power on the first day of intubation and before First trial of weaning:
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Assiut University
Mechanical Power
Mechanical Power Versus Diaphragmatic Excursion As a Predictor for Weaning in Chronic Obstructive Pulmonary Disease Patients
The primary objective is to evaluate the mechanical power as a predictor of weaning of mechanical ventilation in COPD patients hospitalized in the respiratory intensive care unit of Assiut University Hospital.
- Trial name
- weaning (NCT06510517)
- Testing
- Calculation of Mechanical Power., Measurement Diaphragmatic Excursion after first SBT
- Volunteers
- 84 people
- Sponsor
- Assiut University
ARDS, Mechanical Power
Ventilatory Parameters in Predicting Outcomes in ARDS Patients
This is a single-centre prospective observational study aimed to determine if Pocc (occlusion pressure at 100 msec), TCe ( Expiratory time constant ), Mechanical Stress power, Ventilatory ratio and C20/Cdyn would predict outcomes…
- Trial name
- OCTANE (NCT06400095)
- Testing
- Poccl, Time constant, driving pressure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- CentraCare