Clinical trials: Maxillofacial Surgery
Postoperative Pain
Sphenopalatine Ganglion Block in Maxillofacial Surgeries
Patients will be divided into 2 groups, 30 each. Group A will receive sphenopalatine ganglion block via a gauze soaked in local anesthetic introduced in the 2 nostrils then by local anesthetic injected by a cannula into both…
- Trial name
- NCT05854537
- Testing
- Sphenopalatine ganglion block using bupivacaine: xylocaine, Sphenopalatine ganglion block using normal saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Postoperative Pain
Peripheral Nerve Block Techniques During Cleft Palate
Regional blocks are commonly used in pediatric anesthesia to achieve adequate postoperative analgesia. Suprazygomatic Maxillary nerve block (SMN) and Greater Palatine nerve block (GPN) are regional blocks described for use during…
- Trial name
- NCT04467463
- Testing
- peripheral nerve block by 0.25% levobupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Unilateral Cleft Lip and Palate, Cleft Lip
Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate Patients
The purpose of this study is to evaluate which surgical protocol for treating Unilateral Cleft Lip and Palate (UCLP), a single or two stage repair ( with hard palate late closure) will have less impact in mid facial growth.
- Conditions
- Unilateral Cleft Lip and Palate, Cleft Lip, Cleft Palate, Developmental Disabilities
- Trial name
- NCT02329509
- Testing
- two stage palate surgical repair, One stage Palate Surgical repair
- Volunteers
- 64 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Fear, Dental
Validation of Universal Scale in Oral Surgery (USOS) for Patient's Psycho-emotional Status Rating
Patient's psycho-emotional status is being affected during various dental procedures causing patient's and doctor's discomfort. There are three basic factors, composing psycho-emotional status: fear, stress and pain sensitivity.
- Trial name
- NCT03165448
- Testing
- Pre-operative USOS scale testing, Pre-operative SDPQ, MDAS and VAS testing, Post-operative doctor's reported USOS
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Inesa Astramskaitė
Oropharyngeal Cancer
Primary Radiotherapy Versus Primary Surgery for HPV-Associated Oropharyngeal Cancer
The goal of this randomized treatment de-escalation study is to formally compare outcomes in HPV related oropharyngeal cancer tumors treated with a primary radiotherapy versus a primary surgical approach, to provide a high level…
- Trial name
- ORATOR2 (NCT03210103)
- Testing
- Radiation, Transoral Surgery (TOS) + Neck Dissection
- Where
- 9 sites in Australia, Canada
- Volunteers
- 61 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Mandibular Fracture, Virtual Plan of Mandibular Fracture
Evaluation of the Accuracy of 3d Printed Reduction Guide in Treatment of Mandibular Fractures Using Two Different Methods of Virtual Planning
This study will evaluate the accuracy of the use of 3-D printed reduction guide in treatment of mandibular fractures using two different methods of virtual planning.
- Trial name
- NCT07385924
- Testing
- Mandibular fracture treatment by 3d printed guide where virtual planning will be done using the manual reduction technique., Mandibular fracture treatment by 3d printed guide where virtual planning will be done using the mirror image reduction technique.
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Alexandria University
Impacted Third Molar Tooth, Osteotomy
Fracture Pattern Following Bilateral Sagittal Split Osteotomy With or Without Impacted Third Molars
The goal of this clinical trial is to investigate the hypothesis that there are none difference in the treatment result of orthognathic surgery on the lower jaw, with interoperative wisdom tooth removal rather than preoperative…
- Conditions
- Impacted Third Molar Tooth, Osteotomy, Orthognathic Surgery, Mandibular Fractures
- Trial name
- NCT06338982
- Testing
- Interoperative wisdom tooth removal in conjunction with BSSO
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Kimie Bols Østergaard
Impacted Mandibular Third Molar
Cyanoacrylate Adhesive in Impacted Mandibular Third Molars Surgery
The goal of this randomized clinical trial is to evaluate whether cyanoacrylate tissue adhesive can improve postoperative outcomes compared with conventional silk sutures in patients undergoing surgical removal of impacted…
- Trial name
- NCT07445724
- Testing
- cyanoacrylate tissue adhesive, Silk Sutures
- Where
- 2 sites in Vietnam
- Volunteers
- 23 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Rehabilitation, Neck Cancer
Rehabilitation Nursing Program in Otolaryngology
The European Commission's current political guidelines demonstrate into a joint plan aimed at improving and controlling cancer disease. Head and neck cancer (HNC) are the sixth most common cancer worldwide.
- Conditions
- Rehabilitation, Neck Cancer, Otorhinolaryngologic Neoplasms
- Trial name
- NCT05246891
- Testing
- rehabilitation nursing
- Where
- Portugal
- Volunteers
- 151 people
- Sponsor
- University of Évora
Zygomatic Fractures
Evaluation of Navigation Assisted Reconstruction of Posttraumatic Zygomatic Deformity
Treatment of late deformities following fractures of the orbitozygomaticomaxillary complex can be considered a formidable challenge, even to the skilled surgeon.
- Trial name
- NCT01487018
- Testing
- Navigation Surgery, Traditional Surgery
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Peking University
Pediatric and Adult: Mucosal Closure in Facial and Oral Surgery, Pediatric and Adult: Skin Closure (Dermal Sutures)
Prospective, International Monosyn® Quick - Non Interventional Study
The Monosyn® Quick non-interventional study (NIS) has been designed to implement an action within the framework of a proactive post-market surveillance system.
- Conditions
- Pediatric and Adult: Mucosal Closure in Facial and Oral Surgery, Pediatric and Adult: Skin Closure (Dermal Sutures), Women: Episiotomy, Pediatric: Urological Interventions (Circumcision, Phimosis Etc.)
- Trial name
- PRIMOQ (NCT03355001)
- Testing
- Monosyn® Quick
- Where
- 3 sites in Germany
- Volunteers
- 153 people
- Sponsor
- Aesculap AG
Cleft Palate
The Role of Antibiotic Prophylaxis in Cleft Palate and Velopharyngeal Insufficiency Repair
Cleft Lip and Palate surgical repair is one of the most common procedures performed by Plastic and Reconstructive Surgeons in the World.
- Trial name
- Cleft Palate (NCT02688634)
- Testing
- Amoxicillin
- Where
- 2 sites in United States
- Sponsor
- University of Florida
Surgical Blood Loss
Assessment of Hematologic Parameters Before and After Bimaxillary Orthognathic Surgery
The purpose of the present study was to compare some hematologic parameters and operation time in patients who underwent esthetic bimaxillary surgery under hypotensive anesthesia.
- Trial name
- NCT02364765
- Testing
- Remifentanil
- Where
- Brazil
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Dentofacial Deformities
Custom Titanium Plates vs. 3D Splints in LeFort I Osteotomy
This randomized comparative study evaluates the accuracy and feasibility of two techniques for maxillary repositioning in Le Fort I osteotomy: Customized titanium plates (splintless technique) Three-dimensional (3D)-printed…
- Trial name
- NCT06933628
- Testing
- Patient-Specific Titanium Plates, 3D-Printed Intermediate Splint
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Al-Azhar University
Anesthesia, Pain, Postoperative
The Evaluation of the Effect of Preoperatively Applied Throat Lozenge
Purpose:The aim of this study is to evaluate the effect of preoperative throat lozenge on pain relief in the postoperative period of the mucosal damage caused by intubation in patients who underwent operations in the head and…
- Trial name
- NCT06114771
- Testing
- strepsilis
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Wound Healing, Wound Healing Complication
Sutureless Versus Conventional Suturing in Oral Surgery
This randomized clinical study compares sutureless wound closure using n-butyl-2-cyanoacrylate tissue adhesive with conventional silk suturing following minor oral surgical procedures.
- Conditions
- Wound Healing, Wound Healing Complication, Postoperative Pain, Oral and Maxillofacial Surgery Complications
- Trial name
- NCT07856524
- Testing
- Sutureless Wound Closure Using n-Butyl-2-Cyanoacrylate, Conventional Suturing
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- Jouf University
Pain, Postoperative, Anxiety, Dental
Identification of Predictive Factors of Postoperative Pain After Oral Surgery From Phenotypic Parameters Easily Accessible Preoperatively (PHEDOPO)
This project aims to study various predictive factors of postoperative pain after oral surgery among different parameters accessible preoperatively, in order to build a predictive model.
- Trial name
- PHEDOPO (NCT05405088)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 148 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cleft Lip and Palate, Maxillary Hypoplasia
Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?
Cleft lip and palate patients normally present with a sunken face due to collapse in the middle part of the face and inability of the upper and lower teeth to meet during chewing.
- Trial name
- NCT00930124
- Testing
- Orthognathic surgery, Distraction osteogenesis
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Mandible Fracture
Computer Guided Lag Screw Fixation Versus Conventional Lag Screw Fixation in Anterior Mandibular Fractures
Comparison between computer guided lag screw fixation versus traditional lag screw fixation in open reduction and internal fixation of anterior mandibular fractures.
- Trial name
- NCT03530891
- Testing
- Computer guided lag screw fixation, Conventional lag screw fixation
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Cairo University
Maxillofacial, Osteotomy
The Use of Piezoelectric Surgery for Osteotomies
Piezo-surgery was first used in oral and maxillofacial surgery in 2001 by Vercellotti and colleagues to simplify maxillary sinus surgery by avoiding perforation of the schneiderian membrane.
- Trial name
- NCT05202444
- Testing
- Osteotomy using piezoelectrical device
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Minia University