Clinical trials: Maxillofacial Abnormalities
Malocclusion, Craniofacial Morphology
Research on Deep Learning-Based Intelligent Diagnosis and Treatment
This study aims to develop and evaluate deep learning-based artificial intelligence models for craniomaxillofacial multi-modal imaging analysis and clinical decision support.
- Conditions
- Malocclusion, Craniofacial Morphology, Dentofacial Deformities
- Trial name
- NCT07551622
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Xi'an Jiaotong University
Velopharyngeal Insufficiency, Real Time MRI
Etiological Study of Persistent Velopharyngeal Insufficiency in Children With Operated Velopalatine Cleft by Analysis of Velopharyngeal Motor Skills in Static and Dynamic MRI
Velopharyngeal insufficiency is defined as the inability of the soft palate to isolate the nasopharynx from the oropharynx. It is a frequent sequela in patients with a velopalatine cleft despite anatomical restoration of the soft…
- Conditions
- Velopharyngeal Insufficiency, Real Time MRI, Cleft Palate
- Trial name
- FENTIRM (NCT06072495)
- Testing
- real time MRI
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Maxillary Hypoplasia
Orthodontic Retention on the Maxillary Stability After SARME Using Laser Scanner
The objective of this study was to evaluate the effect of the orthodontic retainer on transverse maxillary dental and skeletal stability after SARME.
- Trial name
- NCT01770782
- Testing
- Surgically Assisted Rapid Maxillary Expansion (SARME), Laser Scanner
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Max Domingues Pereira
Recovery After Cleft Palate Surgery
Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate Surgery
A cleft deformity of the lip and/or palate is one of the commonest major birth defects. Primary surgery of cleft palates (CP) varies according to the different surgical teams.
- Trial name
- NCT02923869
- Testing
- Levobupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cleft Lip and Palate, Maxillary Hypoplasia
Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?
Cleft lip and palate patients normally present with a sunken face due to collapse in the middle part of the face and inability of the upper and lower teeth to meet during chewing.
- Trial name
- NCT00930124
- Testing
- Orthognathic surgery, Distraction osteogenesis
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Craniofacial Abnormalities, Cleft Lip
FaceBase Biorepository
The purpose of this study is to find out if there are any genetic differences between people with and without disorders of the head, face, and eye.
- Conditions
- Craniofacial Abnormalities, Cleft Lip, Cleft Palate
- Trial name
- NCT01252264
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Jeff Murray
Cleft Palate
Efficacy of Oral Versus Intravenous Acetaminophen for Primary Pediatric Cleft Palate Repair
The purpose of this investigator-initiated study is to determine whether acetaminophen is an effective pain reliever for primary cleft palate repair in children and possesses opioid sparing effects.
- Trial name
- NCT01500109
- Testing
- Oral acetaminophen, Ofirmev®, Opioid only
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Loma Linda University
Nasal Septum; Deviation, Congenital, Cleft Lip and Palate
Three Dimensional Changes on Nasal Septum and Alveolar Cleft After Maxillary Expansion
This study evaluates, by means of cone beam computed tomography (CBCT), the alterations in the nasal septum and alveolar cleft volume that occur in cleft lip and palate (CLP) patients after rapid maxillary expansion(RME).
- Conditions
- Nasal Septum; Deviation, Congenital, Cleft Lip and Palate, Maxillary Hypoplasia
- Trial name
- NCT03976609
- Testing
- Maxillary Expansion
- Volunteers
- 40 people
- Sponsor
- Pontifícia Universidade Católica de Minas Gerais
Cleft Palates
Preventing Complications in Cleft Palate Repair With Antibiotics
The primary objective of this study is to determine the efficacy of administering a single dose of preoperative antibiotics to prevent complications in patients undergoing primary closure of a cleft secondary palate.
- Trial name
- NCT00760006
- Testing
- Unasyn, saline solution
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Joseph Losee
Cleft Lip, Cleft Palate
Primary Palatoplasty in Pediatric Patients - A Retrospective Review of Surgical Outcomes
Children who are born with cleft palate need surgery in order to correct the problem. The surgery is needed because the defect allows food to leak into the nose.
- Trial name
- NCT01380171
- Where
- United States
- Volunteers
- 1,295 people
- Sponsor
- Children's Healthcare of Atlanta
Orthognathic Surgical Procedures, Psychiatric Disorders
Incidence of Body Dysmorphic Disorder (BDD) in a Population of Patients Undergoing Orthognathic Surgery
Assessment of the incidence of Body dismorphic disorder in a population candidated to orthognathic surgery
- Conditions
- Orthognathic Surgical Procedures, Psychiatric Disorders, Prognathism
- Trial name
- IBDOS (NCT06879275)
- Testing
- Questionnaire and Physical Exam
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Mandibular Hypoplasia, Relapse
Evaluation of Early Relapse After Mandibular Lengthening Surgery
The goal of this study is to evaluate whether the use of a bone graft substitute at the osteotomy site will result in better stability and diminish early relapse after mandibular lengthening surgery.
- Trial name
- NCT03710512
- Testing
- Bilateral sagittal split osteotomy
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitair Ziekenhuis Brussel
Orofacial Myofunctional Disorders, Myo Munchee
Trial to Compare the Effects of Myo Munchee Therapy and Oral Motor Therapy (OMT) in Pediatric Patients to Treat Maxillary Deficiency and Orofacial Myofunctional Dysfunction (OMD).
Multi-center, 6-month, randomized, and controlled trial to compare the effects of Myo Munchee therapy and Oral Motor Therapy (OMT) in pediatric patients (aged 3-5 years) to treat maxillary deficiency and orofacial myofunctional…
- Conditions
- Orofacial Myofunctional Disorders, Myo Munchee, Oral Motor Therapy, Maxillary Deficiency
- Trial name
- NCT07088055
- Testing
- Chewing device only, Myo Munchee and Oral Motor Therapy Treatment, Oral Motor Therapy Treatment Arm
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Myo Munchee (Operations) Pty Ltd
Dentofacial Deformities
Correlation Between Dental Inclination and Bone Thickness in Patients With Class III Dentofacial Deformities
The correlation between tooth inclination and bone thickness and the comparison between thickness measurements and buccolingual inclination before and after dental decompensation will be evaluated through tridimensional images in…
- Trial name
- NCT02491619
- Testing
- orthodontic decompensation
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Michelle Sendyk
Pierre Robin Sequence
Pierre Robin Sequence Outcome Assessment Multi Institutional Study
The purpose of this prospective, multi-center, longitudinal study is to assess clinical outcomes related to the surgical treatment of PRS ( Pierre Robin Sequence) by MDO (Mandibular distraction osteogenesis).
- Trial name
- PROMIS (NCT02432638)
- Where
- United States
- Sponsor
- NYU Langone Health
Dentofacial Deformities, Dentofacial Anomalies [Including Malocclusion] and Other Disorders of Jaw (M26-M27)
Effect of Proximal Segment Positioning on Postoperative Condylar Remodeling in Bimaxillary Orthognathic Surgery
Bimaxillary orthognathic surgery is a surgical procedure that involves simultaneous corrections to both the maxilla (upper jaw) and mandible (lower jaw).
- Trial name
- NCT06897787
- Testing
- manuel positioning group, mandibular basis osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Orthognathic Surgery, Dentofacial Deformities
Development and Validation of an Automated Three-dimensional Cephalometry Method
This study is aimed to develop and assess the validity of an algorithm for automated three-dimensional cephalometry.
- Trial name
- AutoCEPH-3D (NCT04464252)
- Where
- France
- Volunteers
- 453 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Jaw Abnormalities
A Modified Minimally Invasive Approach Towards Le Fort I Osteotomy: a Prospective Study
Nowadays, maxillary Le Fort I osteotomy is a safe and routinely performed procedure. The conventional approach is characterized by a vestibular incision extending from molar-to-molar, associated with a pterygomaxillary…
- Trial name
- MILF-I (NCT02660216)
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- AZ Sint-Jan AV
Craniofacial Abnormalities, Maxillofacial Abnormalities
3D Imaging of Hard and Soft Tissue in Orthognathic Surgery
The primary objective of this clinical trial is to assess the influence of orthognathic surgery on facial soft tissue, such as changes (volume, linear, angular) of facial hard and soft tissue, in three dimensions, so enabling the…
- Conditions
- Craniofacial Abnormalities, Maxillofacial Abnormalities, Cleft Lip, Cleft Palate
- Trial name
- NCT00285714
- Testing
- 3D stereophotogrammetric imaging, 3D CT-imaging with cone-beam CT, Case report form
- Where
- 3 sites in Netherlands
- Volunteers
- 450 people
- Sponsor
- Radboud University Medical Center
Palatal Expansion Technique, Cleft Lip and Palate
MARPE in Patients With Cleft Lip and Palate
The objective of this randomized controlled study will be to evaluate the dental and skeletal effects of maxillary protraction with a facemask, associated with MARPE and Class III elastics in patients with unilateral cleft lip…
- Conditions
- Palatal Expansion Technique, Cleft Lip and Palate, Class III Malocclusion, Skeletal Malocclusion
- Trial name
- NCT04354116
- Testing
- Rapid maxillary expansion, Maxillary Protraction
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pontifícia Universidade Católica de Minas Gerais