Clinical trials: Maxillofacial Abnormalities
Orthognathic Surgery, Maxillofacial Abnormalities
Study Evaluating the Performance and Safety of Global D Implants Indicated for Orthognathic Surgery
This study is set up within the framework of the European Union regulation 2017/745 on medical devices. Its objective is to confirm the performance and safety of the Global D implants (ORTRAUTEK® and MINITEK®) used for…
- Conditions
- Orthognathic Surgery, Maxillofacial Abnormalities, Maxilla Fracture
- Trial name
- CMF-ORTHO (NCT05271383)
- Testing
- Orthognathic surgery using Global D's implants.
- Where
- France
- Volunteers
- 198 people
- Sponsor
- Global D
Maxillofacial Deformity, Maxillofacial Abnormalities
a Comparative Analysis of Subspinal and Conventional Le Fort I Osteotomy on Nasolabial Soft Tissues
Following surgical operations, patients have aesthetic expectations as well as functional ones. To minimize undesirable aesthetic results after surgery and to increase the effectiveness of the surgery, the surgical method used…
- Conditions
- Maxillofacial Deformity, Maxillofacial Abnormalities, Maxillo-facial Surgery
- Trial name
- NCT07549659
- Testing
- conventional le fort I osteotomy type, subspinal le fort I osteotomy type
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Maxillofacial Abnormalities
Evaluation of the Long-term Results of Extended Supra-basillary Genioplasty of the "Chin Wing" Type Without Bone Graft
The correction of maxillomandibular dysmorphoses, responsible for both functional discomfort (lip incompetence, ventilation disorders, periodontal disease) but also aesthetic, calls in particular for genioplasty, of which there…
- Trial name
- SASCWatch (NCT06183853)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Strasbourg, France
Prosthetic Treatment, Craniofacial Abnormalities
Digital Design for Maxillofacial Prosthetics
This study will use a 3D scanner to print a 3D model or mold for each patient's prosthesis. The goal of this study to provide patients with a new, faster method of imaging and creating prostheses that preserves the quality of the…
- Conditions
- Prosthetic Treatment, Craniofacial Abnormalities, Maxillofacial Abnormalities
- Trial name
- NCT04035928
- Testing
- 3D digital scanning for maxillofacial prosthetics
- Where
- United States
- Sponsor
- University of Michigan
Emesis, Postoperative, Maxillofacial Abnormalities
Effects of Antiemetic Agents in Orthognathic Surgery Patients
In an effort to prevent or treat consistently high rates of PONV following maxillofacial operations, several medications, techniques and multimodal protocols have been studied.
- Trial name
- NCT06454825
- Testing
- Intravenous drug
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Maxillofacial Abnormalities
Does Subspinal Le Fort I Osteotomy Affect the Nasal Airway Volume
After the description of Le Fort fractures, maxillary osteotomies are used to correct dentofacial deformities. The profile changes on nasolabial region resulting from a Le Fort I osteotomy, also that affects nasal airway.
- Trial name
- NCT06281197
- Testing
- Conventional, Subspinal
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Maxillofacial Abnormalities
Ultrasonic Bone Scalpel in BSSO
The conventional saw compared with the piezo surgery in BSSO to evaluate cutting time, surgery duration, amount of bleeding. The purpose of this study was to answers following clinical questions: Is ultrasonic bonescalpel…
- Trial name
- NCT06273189
- Testing
- Conventional, Bone Scalpel
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Maxillofacial Abnormalities
Maxillofacial Rehabilitation Using Motor Imagery vs Sham After Orthognathic Surgery
Dento-maxillary dysmorphoses are defined as an anomaly in the relative growth of the maxilla and/or mandible. They lead to functional disorders (i.e., disturbances in chewing or oral communication) and aesthetic issues with…
- Trial name
- MAXIMAND (NCT06263374)
- Testing
- Motor imagery of the jaw, Control task (Sudoku or Crossword puzzle)
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Maxillofacial Abnormalities
Impact of Maxillomandibular Deformities on Individuals' Nutritional Status
This cross-sectional study explores the influence of various types of maxillomandibular deformities on the nutritional status of individuals.
- Trial name
- NCT05936476
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Marmara University
Maxillofacial Abnormalities, Mandible Prognathism
Condylar Position Changes and TMJ Functions After BSSO Mandibular Setback, Low Medial Cut.
This study hypotheses that using low medial cut osteotomy BSSO in mandibular setback can be an efficient and effective method to limit the bony segment interferences , decreasing muscles stripping during osteotomy ,decrease…
- Conditions
- Maxillofacial Abnormalities, Mandible Prognathism, Skeletal Malocclusion
- Trial name
- NCT05713084
- Testing
- mandibular setback using BSSRO
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maxillofacial Abnormalities, Maxillofacial Injuries
Vitamin C Level Effect in Orthognathic Surgery
Comparing the pre and post-operative blood plasma levels of vitamin C according to oxidative stress and investigate the correlation between post-operative analgesia requirement and vitamin C levels following orthognathic surgery.
- Conditions
- Maxillofacial Abnormalities, Maxillofacial Injuries, Maxillofacial Trauma
- Trial name
- NCT04416386
- Testing
- Vitamin C
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Maxillofacial Injuries, Maxillofacial Trauma
Superficial Cervical Plexus Block for Orthognathic Surgery
US-guided superficial cervical plexus block (SCPB) may be used for several head and neck surgeries. Local anesthetic is injected under the sternocleidomastoid muscle for SCPB.
- Conditions
- Maxillofacial Injuries, Maxillofacial Trauma, Maxillofacial Abnormalities, Maxillofacial Dysostosis
- Trial name
- NCT04442009
- Testing
- Group SCPB
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Maxillofacial Abnormalities, Jaw Abnormalities
Digital Occlusal Wafer Versus Waferless Distal Segment Repositioning for BSSO in Skeletal Mandibular Deformities
Research studies continues to attempt testing modifications to refine the treatment protocols through computer assisted design or computer-generated surgical Wafer splints, have greatly revolutionized the incorporation of digital…
- Conditions
- Maxillofacial Abnormalities, Jaw Abnormalities, Prognathism, Retrognathia
- Trial name
- NCT05151042
- Testing
- wafer-less approach, Computer Guided orthognathic surgery using occlusal wafers
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maxillofacial Abnormalities, Computer-assisted Surgery
Adherence to Computer-assisted Maxillofacial Reconstructions
The study was approved by the Local Ethics Committee and was conducted in compliance with the World Medical Association Declaration of Helsinki on medical research.
- Conditions
- Maxillofacial Abnormalities, Computer-assisted Surgery, Virtual Surgical Planning
- Trial name
- NCT04895319
- Testing
- Computer-assisted surgery
- Volunteers
- 136 people
- Sponsor
- KU Leuven
Maxillofacial Abnormalities, Blood Pressure
Review of Anaesthetic Practice in Orthognathic Surgery
Orthognathic surgeries for maxillofacial deformities are commonly performed globally. However, they are associated with significant blood loss which can affect the surgical field and result in blood transfusion and its risks.
- Conditions
- Maxillofacial Abnormalities, Blood Pressure, Anesthesia
- Trial name
- NCT04813289
- Where
- Singapore
- Volunteers
- 269 people
- Sponsor
- Singapore General Hospital
Maxillofacial Abnormalities, Post Procedural Discharge
Impact of Manual Lymphatic Drainage on Postoperative Edema of the Face and the Neck After Orthognathic Surgery
Orthognathic surgery aims to standardize position of the maxilla and the mandible and therefore chewing, breathing, phonation and swallowing functions.
- Trial name
- DLMOF (NCT01983436)
- Testing
- Manual Lymphatic drainage
- Where
- 2 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Tours
Orthognathic Surgery, Maxillofacial Abnormalities
Accuracy of Maxillary Repositioning During Orthognathic Surgery
Orthognathic surgery aims to correct jaw position taking into account esthetic and functional criteria (dental occlusion, lip position, breathing...). These surgeries are planned using clinical, radiological and dental cast data.
- Trial name
- POMOCOBS (NCT03357211)
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Oral Mucosal Disease
Clinical Research Core Dental Screening Protocol
This study will screen patients for eligibility in studies sponsored by the Craniofacial Genetics Section (HCGS), the Clinical Research Core (CRC), and other branches located within the National Institute of Dental and…
- Trial name
- NCT00090818
- Where
- United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Cleft Palate, Jaw Abnormalities
Improving Informed Consent for Cleft Palate Repair
To determine if providing a written document in addition to the standard oral discussion of surgical risks improves risk recall for the parents/guardians of a child seen in consultation for cleft palate surgery, and if this has…
- Conditions
- Cleft Palate, Jaw Abnormalities, Maxillofacial Abnormalities, Mouth Abnormalities
- Trial name
- NCT02595307
- Testing
- Pamphlet
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- IWK Health Centre
Maxillofacial Abnormalities
Mandibular Stability and Dentofacial Deformity
The present study intends to clarify whether there is positional mandibular stability in patients to be submitted to orthognathic surgery.
- Trial name
- NCT01486069
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo