Clinical trials: Maxillary Expansion
Narrow Maxilla
Efficacy of Mini-implant Assisted Maxillary Expansion in Adolescents and Adults
Transverse maxillary deficiency is a common orthodontic issue, affecting around 10% of adults. Late adolescents and adults often require more force to expand the midpalatal suture due to its increased interdigitation.
- Trial name
- MARPE_1 (NCT06449014)
- Testing
- Mini-implants assisted maxillary expansion
- Where
- 2 sites in Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Maxillary Transverse Deficiency
Evaluation of the Effect of Surgically Assisted Rapid Maxillary Expansion on Tooth Color
This prospective study aimed to evaluate effects of surgically assisted rapid maxillary expansion (SARME) on the color, maxillary anterior teeth by comparing them with untreated control group.
- Trial name
- NCT07150572
- Testing
- surgery assisted rapid maxillary expansion
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Apnea, Airway Obstruction, Nasal
Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion
Breathing is a crucial function for everyone. Breathing impairment in children could lead to behavioral and cognitive problems at least.
- Conditions
- Apnea, Airway Obstruction, Nasal, Mandible Small, Maxillary Hypoplasia
- Trial name
- NCT04190953
- Testing
- Twin block then Hyrax, Hyrax then Twin block
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Posterior Cross Bite
Cone Beam Computed Tomography for Evaluating Corticotomy-assisted Maxillary Expansion
Maxillary expansion was performed for adult female patients suffering from maxillary constriction with bilateral posterior cross-bite using fixed Quad-helix appliance, for about 8 months.
- Trial name
- NCT02574117
- Testing
- flap with corticotomy and bone allograft
- Where
- Egypt
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Cairo University
Palatal Expansion Technique
Investigation of Skeletally Anchored Expansion of the Maxilla
This study aims to compare two different methods for maxillary expansion in adult patients with transverse maxillary deficiency. Participants will receive either miniscrew-assisted rapid palatal expansion (MARPE-MICRO-4).
- Trial name
- NCT07383376
- Testing
- MARPE, SARME
- Where
- Hungary
- Volunteers
- 90 people
- Sponsor
- Semmelweis University
Maxillary Expansion
Effects of Skeletal Anchored Maxillary Expander for Constricted Maxilla
The aim of study will be Evaluation of Effects of skeletal anchored maxillary expander for constricted maxilla with different patient's age
- Trial name
- NCT07036822
- Testing
- Skeletal Anchored Maxillary Expander (MARPE)
- Volunteers
- 24 people
- Sponsor
- Samar Hassan Mahmoud Mohamed
Maxillary Expansion
Rapid Maxillary Expansion Related Oxidative Stress and Periodontal Results
The aim of this study was to investigate the effects of rapid maxillary expansion on local and systemic oxidative stress levels.
- Trial name
- NCT06937775
- Testing
- Periodontal measurements (plaque index, gingival index and probing pocket depth scores ), Biochemical Sample Supply (Collection of serum and saliva samples), Rapid maxillary expansion with Hyrax appliance
- Volunteers
- 35 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Nasal Septum; Deviation, Congenital, Cleft Lip and Palate
Three Dimensional Changes on Nasal Septum and Alveolar Cleft After Maxillary Expansion
This study evaluates, by means of cone beam computed tomography (CBCT), the alterations in the nasal septum and alveolar cleft volume that occur in cleft lip and palate (CLP) patients after rapid maxillary expansion(RME).
- Conditions
- Nasal Septum; Deviation, Congenital, Cleft Lip and Palate, Maxillary Hypoplasia
- Trial name
- NCT03976609
- Testing
- Maxillary Expansion
- Volunteers
- 40 people
- Sponsor
- Pontifícia Universidade Católica de Minas Gerais
Control Patients, Class III Malocclusion
Effect of Face Mask Therapy on Blood Oxygen Levels
Skeletal Class III malocclusions are characterized by maxillary retrusion, mandibular protrusion, or a combination of both. In growing individuals presenting with maxillary deficiency, the face mask appliance is widely recognized…
- Trial name
- NCT06939179
- Testing
- Class III Malocclusion
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Biruni University
Class III Skeletal Malocclusion
Comparative 3D Assessment of Class III Malocclusion Treatments
This clinical trial compares three different treatment methods used to correct jaw problems in children with Class III malocclusion (a condition where the lower jaw is positioned forward relative to the upper jaw).
- Trial name
- CLASSIII-3D (NCT07179354)
- Testing
- Rapid Maxillary Expansion with Face Mask (RME/FM), Mini Maxillary Protractor (MMP), Modified Splint with Elastics and Chin Cup (Modified SEC III)
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- TC Erciyes University
Cleft Lip and Palate, Maxillary Expansion
Effectiveness of Two Maxillary Expanders in Improving the Transverse Skeletal and Dental Dimensions in Patients With Cleft Lip and Palate
This randomized controlled trial is designed to compare between quadlelix appliance vs hyrax expander regrading the their effectiveness in maxillary expansion in patients with cleft.
- Trial name
- NCT04331977
- Testing
- Maxillary Expansion
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Expansion of Maxillary Arch, Maxillary Hypoplasia
Dentoskeletal Changes Expansion Using Invisalign Versus Conventional Expander
Cbct evaluation of dentoskeletal changes after expansion using Invisalign versus conventional expander
- Trial name
- NCT05899530
- Testing
- Invisalign, Conventional expander
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Sleep Apnea Syndrome, Rapid Maxillary Expansion
Evaluation of the Effects of Different Rapid Maxillary Expansion Appliances on Obstructive Sleep Apnea
Rapid maxillary expansion (RME) is a commonly used orthodontic treatment in patients with maxillary constriction to provide skeletal expansion, correct posterior crossbite and resolve naso-respiratory problems by reducing oral…
- Trial name
- NCT04604392
- Testing
- Rapid Maxillary Expansion Treatment
- Volunteers
- 46 people
- Sponsor
- Izmir Katip Celebi University
Maxillary Transverse Deficiency
Effectiveness of Clear Aligner Systems in Mixed Dentition Maxillary Transverse Deficiency
he primary aim of this study is to compare the dentoalveolar and skeletal effects of arch expansion using an in-house clear aligner system, produced chairside with an indirect manufacturing technique, and commercially available…
- Trial name
- NCT07586163
- Testing
- Invisalign Palatal Expander Therapy, In-House Clear Aligner Therapy (2-Day Protocol), In-House Clear Aligner Therapy (5-Day Protocol)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- TC Erciyes University
Malocclusion, Maxillary Expansion
Treatment of Unilateral Posterior Cross Bite in Children
Rapid maxillary expansion and quad-helix are two well established appliances in dentistry used for posterior cross bite treatment.
- Conditions
- Malocclusion, Maxillary Expansion, Pain Children
- Trial name
- NCT04458506
- Testing
- Maxillary expansion
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Crowding of Anterior Maxillary Teeth, Orthodontics, Interceptive
Interceptive Maxillary Expansion to Relief Anterior Crowding in the Mixed Dentition
The goal of this clinical trial is to compare if it is better to treat severe anterior crowding in the early mixed dentition then later in the permanent dentition in children with anterior crowding of the upper teeth.
- Conditions
- Crowding of Anterior Maxillary Teeth, Orthodontics, Interceptive, Orthodontics, Corrective, Palatal Expansion Technique
- Trial name
- NCT06187337
- Testing
- Maxillary expansion device
- Where
- 4 sites in Italy, Sweden
- Volunteers
- 60 people
- Sponsor
- Region Örebro County
Maxillary Deficiency
Maxillary Expansion: Leaf Expander Versus Hyrax Expander
The aim of the current study was to evaluate maxillary and mandibular arch widths' response to five different appliances and clinical protocols (Rapid maxillary expander RME, Leaf Expander 450g, Leaf Expander 900g, Self-expander…
- Trial name
- LEAF (NCT05135962)
- Testing
- orthodontic - rapid maxillary expansion, orthodontic - slow maxillary expansion with leaf expander, orthodontic - slow maxillary expansion with self leaf expander
- Volunteers
- 200 people
- Sponsor
- University of Genova
Maxillary Expansion, Forensic Dentistry
Evaluation of Palatal Rugae-Based Identification After Maxillary Expansion Using Local Morphological Patch Analysis
This study investigates the reliability of palatal rugae-based identification following maxillary expansion procedures, including Miniscrew-Assisted Rapid Palatal Expansion (MARPE) and Surgically Assisted Rapid Maxillary…
- Conditions
- Maxillary Expansion, Forensic Dentistry, Intraoral Scanner, Orthodontic Appliance
- Trial name
- NCT07667933
- Testing
- SARME, MARPE, Untreated Control
- Where
- Hungary
- Volunteers
- 45 people
- Sponsor
- Semmelweis University
Maxillary Transverse Deficiency Class I Malocclusion Vitamin D Deficiency Orthodontic Tooth Movement Adolescent Health
Effect of Serum Vitamin D on MARPE Treatment Response
A total of 30 patients are planned to be included in the study during the first half of 2025, who will apply to the clinic. In our clinical routine, approximately 30% of RME patients are treated using the MARPE method.
- Trial name
- NCT06943443
- Testing
- Miniscrew-Assisted Rapid Palatal Expansion (MARPE) Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Obstructive Sleep Apnea
Assessment of the Impact on the Quality of Life of Surgically Assisted Maxillary Expansion in Adult Patients Followed for Obstructive Sleep Apnea Syndrome
The research aims to assess the impact on quality of life of surgically maxillary expansion in adult patients followed for obstructive sleep apnea syndrome.
- Trial name
- QUAVIMAX (NCT04618991)
- Testing
- Filling the Quebec Sleep Questionnaire
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris