Clinical trials: Maternal Nutrition
Pregnancy Complications, Maternal Death
Nutrition Optimalization Among Pregnant Women to Improve Maternal and Neonatal Outcome in DKI Jakarta
The goal of this MONAS Study is to learn about comprehensive monitoring and nutritional intervention among pregnant women in order to improve maternal and neonatal outcomes. The main questions it aims to answer are: 1.
- Conditions
- Pregnancy Complications, Maternal Death, Preeclampsia, Intrauterine Infection
- Trial name
- MONAS (NCT06268509)
- Testing
- Nutritional panel laboratory examination, Pregnancy supplements (other than provided by Ministry of Health), Fetomaternal ultrasound
- Where
- Indonesia
- Volunteers
- 245 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Breastfeeding
Effects of 5-Methyltetrahydrofolic Acid Supplementation on Maternal Health and One-Carbon Metabolism During Lactation
This double-blind, randomized, placebo-controlled parallel trial evaluates the effects of maternal 5-methyltetrahydrofolate (5-MTHF) supplementation during breastfeeding.
- Trial name
- OCMS (NCT07508917)
- Testing
- 5-MTHF Supplementation
- Where
- 2 sites in Spain
- Volunteers
- 36 people
- Sponsor
- Fundació Sant Joan de Déu
Malnutrition
District-based Mainstreaming Nutrition Project in Rural Pakistan
This study aims to provide evidence regarding the feasibility of integrating an enhanced maternal and child care health education package into the existing curricula of the National Program for Family Planning and Primary Health…
- Trial name
- NF Nutrition (NCT00816946)
- Testing
- Enhanced education
- Where
- Pakistan
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Malnutrition, Wasting
Nutritional Impact of Moringa Oleifera Leaf Supplementation in Mothers and Children
Studies to date on the effects of Moringa oleifera in diabetes and anemia and animal studies that examine the utility of moringa for increased milk and litter yield are of small scale, however high-quality large-scale placebo or…
- Conditions
- Malnutrition, Wasting, Growth Failure
- Trial name
- NCT04587271
- Testing
- Moringa oleifera (high dose), Moringa oleifera (low dose)
- Where
- 2 sites in Kenya
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Suzanna L Attia
Vitamin A Deficiency, HIV
Single-dose Postpartum Vitamin A Supplementation of Mothers and Neonates
The ZVITAMBO PROJECT is testing whether giving mothers and infants a single large dose of vitamin A during the immediate post partum period will reduce: 1.
- Trial name
- ZVITAMBO (NCT00198718)
- Testing
- Vitamin A (retinyl palmitate)
- Volunteers
- 28,220 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Post Menopausal Osteoporosis
Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis
Post-menopausal osteoporosis and the resulting fractures are an important cause of disability and loss of independence. They also increase the risk of morbidity and mortality.
- Trial name
- NUTRANACRE (NCT05571514)
- Testing
- Mother-of-pearl, Calcium Carbonate
- Where
- 7 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Depression, Postpartum, Malnutrition, Child
Decreasing Stunting by Reducing Maternal Depression in Uganda: A Cluster Randomized Controlled Trial (CRCT) for Improved Nutrition Outcomes
The project seeks to test the integration of Interpersonal Psychotherapy for Groups within Care Group projects and investigate whether the treatment of maternal depression with Interpersonal Psychotherapy for Groups improves the…
- Trial name
- NCT03573713
- Testing
- Care Groups, IPT-G
- Where
- Uganda
- Volunteers
- 1,248 people
- Sponsor
- Food for the Hungry
Obesity & Overweight
Healthy Eating for My Infant: A Community- Informed Infant Obesity Prevention Program Addressing the Impact of Maternal Mental Health on Eating and Feeding
Infants from low-income families are at increased risk for obesity, but obesity prevention programs tailored specifically to the needs of these infants are lacking.
- Trial name
- NCT07284108
- Testing
- Healthy Eating for My Infant (HEMI)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Iron Deficiency Anemia of Pregnancy
Adiposity and Iron Requirements in Pregnancy
This study aims to explore how body fat influences the response to either 25 or 50 mg of daily iron supplements during pregnancy.
- Trial name
- ADIPREG (NCT06425796)
- Testing
- Adiposity and Iron Requirements in Pregnancy (ADIPREG)
- Where
- 3 sites in United Kingdom
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Thyroid Function
Mothers and Babies at Yorkhill Thyroid Health Cohort
This is an observational study in pregnant mothers and their newborn babies. The rationale of the study is to examine early markers of the effects of iodine insufficiency during pregnancy on thyroid stimulating hormone (TSH) and…
- Trial name
- MABY (NCT02390128)
- Testing
- observational only
- Where
- United Kingdom
- Volunteers
- 697 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Overweight or Obesity
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
The goal of this clinical trial is to test an enhanced version of the National Diabetes Prevention Program (NDPP-NextGen) that is tailored to young women in childbearing years.
- Trial name
- NCT05674799
- Testing
- NDPP-NextGen
- Where
- United States
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Birth Outcomes, Stunting
Uganda Birth Cohort Study
The UBC was a USAID-funded longitudinal prospective cohort study of pregnant women (n= 5030) aged 15-49 years from rural North and South-Western regions of Uganda, conducted between 2014 and 2016.
- Conditions
- Birth Outcomes, Stunting, Wasting, Anemia
- Trial name
- UBC (NCT04233944)
- Where
- United States
- Volunteers
- 5,044 people
- Sponsor
- Tufts University
IBD (Inflammatory Bowel Disease), IBD
Exploring Fecal Calprotectin Levels, Maternal and Infant Microbiota, Infant Health, Nutrition, and Adverse Pregnancy Outcomes With Patient With Inflammatory Bowel Disease
The goal of this prospective longitudinal cohort study is to examine how the human microbiome of pregnant women-including bacteria and fungi in the gastrointestinal tract, vaginal canal, skin, and breastmilk-may influence infant…
- Conditions
- IBD (Inflammatory Bowel Disease), IBD, IBD - Inflammatory Bowel Disease, Pregnancy
- Trial name
- CALINA-IBD (NCT07385807)
- Where
- 2 sites in Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Under Five Child Health Nutrition and Immunization
Naunehal - Integrated Immunization & MNCH Interventions; A Quasi-Experimental Study
Maternal, newborn, and child health (MNCH) are an area of concern in Pakistan with many health and nutrition indicators at sub-optimal levels.
- Trial name
- NCT05135637
- Testing
- Mobile health services, Private practitioner engagement for immunization, Community engagement and mobilization
- Where
- Pakistan
- Volunteers
- 8,100 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Obesity, Obesity, Maternal
Obesity and OSA in Pregnancy
The purposes of this project are 1) to compare the impact of maternal obesity versus excessive gestational weight gain on obstructive sleep apnea (OSA) in obese and non-obese women; 2) to investigate the mechanism(s) by which…
- Conditions
- Obesity, Obesity, Maternal, Obstructive Sleep Apnea, Blood Pressure
- Trial name
- NCT05654259
- Where
- 2 sites in United States
- Volunteers
- 116 people
- Sponsor
- University of Texas Southwestern Medical Center
Healthy Nutrition, Pregnancy Related
Maternal Carotenoids Across Pregnancy Study
Before infants are born, they depend on their mother to provide the nutrients necessary to grow and develop, such as iron, folic acid, iodine and other vitamins and minerals.
- Trial name
- MCAPS (NCT06004479)
- Testing
- Carotenoid Intake, Serum carotenoid concentration
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Overweight, Pregnancy
Effects of Antenatal Nutrition Counseling on Maternal and Infant Outcomes
This randomized controlled trial evaluated whether individualized antenatal nutrition counseling provided between 24 and 36 weeks of gestation could improve maternal dietary quality, dietary inflammatory potential, gestational…
- Trial name
- NCT07845773
- Testing
- Dietitian-Led Nutrition Education and Counseling
- Where
- Cyprus
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Overweight, Obesity
Iron Absorption and Transfer to the Fetus During Pregnancy in Normal Weight and Overweight/Obese Women and the Effects on Infants Iron Status
Overweight and obesity causes low-grade systemic inflammation, which sharply increases risk for iron deficiency. Studies in our laboratory have shown that this is mainly the result of reduced dietary iron absorption because of…
- Conditions
- Overweight, Obesity, Pregnancy
- Trial name
- PIANO (NCT02747316)
- Testing
- Stable iron isotope 57 (57Fe) labeled iron solution, Stable iron isotope 58 (58Fe) labeled iron solution
- Where
- Switzerland
- Volunteers
- 83 people
- Sponsor
- Swiss Federal Institute of Technology
Diabetes Mellitus, Type 2, Pregnancy in Diabetic
The Effect of In-utero Exposure to Metformin in 5-11 Year Old Offspring of Mothers in the MiTy Trial
The incidence of diabetes in pregnancy is rising, with rates of 1 in 7 pregnancies globally. Metformin is used for type 2 diabetes (T2DM) outside of pregnancy and is now increasingly prescribed during pregnancy.
- Conditions
- Diabetes Mellitus, Type 2, Pregnancy in Diabetic, Child Obesity, Child Development
- Trial name
- MiTy Tykes (NCT05025852)
- Where
- 12 sites in Australia, Canada
- Volunteers
- 132 people
- Sponsor
- Mount Sinai Hospital, Canada
Dental Caries, Obesity Risk
Mothers' Action Project for Child Health
This randomized controlled trial will recruit Bangladeshi mothers and their young children into a 12 month intervention that provides child health and oral health education and seeks to build social networks among mothers.
- Trial name
- MAP-CH (NCT06753669)
- Testing
- health education and social network building, dental referral and educational materials
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester