Clinical trials: Maternal Depression
Mother-Infant Interaction
The Effect of the Newborn Behavioral Observations System on Maternal Sensitivity
The study evaluates if the Newborn Behavioral Observation system, a relationship building tool, delivered to at risk mothers will have, on one site, an effect on maternal sensitivity and the other site on Childs responsiveness…
- Trial name
- NCT04739332
- Testing
- The Newborn behavioral observations system
- Where
- Iceland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Center for Parents and Infants, Iceland
Premature, Low Birth Weight
Effect of Kangaroo Baby Massage on Mother-infant Interaction at Home
The objective of this randomized clinical trial will determine the effectiveness of nursing intervention (Kangaroo Baby Massage) on the interaction between mothers and premature, low birth weight infants at home The dyad mother…
- Conditions
- Premature, Low Birth Weight, Mother-Infant Interaction, Gain, Weight
- Trial name
- KBM (NCT04908332)
- Testing
- Kangaroo Baby Massage
- Where
- Colombia
- Volunteers
- 68 people
- Sponsor
- Universidad Nacional de Colombia
Infant, Newborn, Maternal Outcome
The Half Swaddling Application on Infant Sleep Routine, Maternal Sleep Quality, Depression
In this prospective controlled study, it was aimed to examine the effects of half swaddling in term infants on infant sleep routine, maternal sleep quality and postpartum depression.
- Trial name
- Half swaddling (NCT06750796)
- Testing
- The Half Swaddling Application
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Tanta University
Neonatal Death, Perinatal Death
Leveraging Interactive Text Messaging to Monitor and Support Maternal Health in Kenya
Mobile health (mHealth) interventions such as interactive short message service (SMS) text messaging with healthcare workers (HCWs) have been proposed as efficient, accessible additions to traditional health care in…
- Conditions
- Neonatal Death, Perinatal Death, Depression
- Trial name
- AI-NEO (NCT05369806)
- Testing
- Interactive two-way SMS dialogue
- Where
- 2 sites in Kenya
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Depression, Postpartum, Malnutrition, Child
Decreasing Stunting by Reducing Maternal Depression in Uganda: A Cluster Randomized Controlled Trial (CRCT) for Improved Nutrition Outcomes
The project seeks to test the integration of Interpersonal Psychotherapy for Groups within Care Group projects and investigate whether the treatment of maternal depression with Interpersonal Psychotherapy for Groups improves the…
- Trial name
- NCT03573713
- Testing
- Care Groups, IPT-G
- Where
- Uganda
- Volunteers
- 1,248 people
- Sponsor
- Food for the Hungry
Perinatal Depression, PerinatalAnxiety
Perinatal Depression & Anxiety (PDA) and Maternal Gut Microbiome
Perinatal depression and anxiety (PDA) are the leading causes of maternal mortality in developed countries. Women with a history of depression have a 20 fold higher risk of PDA at subsequent pregnancies.
- Trial name
- NCT06074250
- Testing
- Fish oil, Probiotics, Prebiotics
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Postnatal Depression
Tackling Postnatal Depression: Culturally Adapted Learning Through Play Plus (LTP+) Intervention for British Mothers of African and Caribbean Origin
By 2030, depression will be the leading global disease burden. Postnatal depression due to childbirth/parenting leads to long-term negative consequences for mothers, their children and their families.
- Trial name
- NCT05148260
- Testing
- Learning Through Play plus (LTP+), Psychoeducation
- Volunteers
- 80 people
- Sponsor
- Nottingham Trent University
Premature Birth, Low Birth Weight
Pilot Trial of CenteringPregnancy With Mindfulness Skills
In the U.S., rates of preterm birth and low birth weight have increased over the past 30 years. Poor birth outcomes are especially high among racial/ethnic minority populations.
- Conditions
- Premature Birth, Low Birth Weight, Postpartum Depression
- Trial name
- NCT01646463
- Testing
- CenteringPregnancy, CenteringPregnancy with Mindfulness Skills
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Child Development Disorder, Post Partum Depression
Optimization of Mother-child Dyad Follow-up by a Multidomain Application: Real-world Cross Sectional Study
After birth, the mother-child dyad can be impacted by issues which are usually under-detected or detected at early stage. Among these issues, neurodevelopmental disorders (NDD) such as autism spectrum disorder are common and…
- Trial name
- MALO_2 (NCT05215028)
- Testing
- web-application
- Where
- France
- Volunteers
- 4,346 people
- Sponsor
- Weprom
Preterm, Mothers
The Effect of Progressive Muscle Relaxation Exercises
Purpose This study was carried out to examine the effectiveness of Progressive Muscle Relaxation (PMR) exercises on mothers' breastfeeding self-efficacy and depression level with preterm infants.
- Trial name
- NCT05453734
- Testing
- Progressive Muscle Relaxation Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul University - Cerrahpasa
Perinatal Depression
Pilot Study of Mothers and Babies Online in Home Visiting
The investigators propose a pilot randomized controlled trial (RCT) that examines how the redesigned version of Mothers and Babies Online (eMB) can be delivered in the context of home visiting (HV) programs that serve pregnant…
- Trial name
- eMB (NCT05714956)
- Testing
- Mothers and Babies Online (eMB)
- Where
- 6 sites in United States
- Volunteers
- 42 people
- Sponsor
- Northwestern University
Post-partum Depression
Systems of Care for New Moms: Integrating Depression Treatment
NUMOMS involves collaboration between Nurses for Newborns Foundation and Washington University in St. Louis. This study explores the co-location of depression treatment within nurse home visitation and the organizational changes…
- Trial name
- NUMOMS (NCT01407783)
- Testing
- Problem Solving Tools (PST)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Washington University School of Medicine
Mother of a Child With Cerebral Palsy
Effect of Vagus Nerve Stimulation and Breathing Exercise on the Autonomic Nervous System
This project will compare the effects of intraaural vagus nerve stimulation and deep breathing exercises on the autonomic nervous system in mothers of children with cerebral palsy.
- Trial name
- NCT06970769
- Testing
- Vagus nerve stimulation, Deep Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Atlas University
Overweight, Pregnancy
Effects of Antenatal Nutrition Counseling on Maternal and Infant Outcomes
This randomized controlled trial evaluated whether individualized antenatal nutrition counseling provided between 24 and 36 weeks of gestation could improve maternal dietary quality, dietary inflammatory potential, gestational…
- Trial name
- NCT07845773
- Testing
- Dietitian-Led Nutrition Education and Counseling
- Where
- Cyprus
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Mental Health Issue, Substance Use Disorders
Improving Maternal Mental Health & SUD Screening and Treatment
The purpose of the study is to compare a text message-based mental health and substance use screening and referral to a treatment program, called Listening to Women and Pregnant and Postpartum People (LTWP), to standard of care…
- Conditions
- Mental Health Issue, Substance Use Disorders, Postpartum Depression, Postpartum Anxiety
- Trial name
- NCT05764213
- Testing
- Listening to Women & Pregnant and Postpartum People
- Where
- United States
- Volunteers
- 10,469 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Depression
Using the LENA System in Early Intervention
This project will determine whether an intervention to enhance communication between infants and toddlers with developmental disabilities and their depressed mothers can be integrated into federally-funded Early Intervention (EI)…
- Trial name
- NCT03164642
- Testing
- LENA with Feedback, LENA no feedback
- Where
- United States
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Postpartum
The Effect of Magnesium on Maternal Mood, Cognitive Function, and Birth Experience
Magnesium is sometimes used to prevent seizures in the setting of hypertensive disorders of pregnancy. The primary aim of this study is to determine if women who receive magnesium are less likely to experience postpartum…
- Trial name
- NCT02454322
- Testing
- Magnesium Sulfate
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Post Partum Depression
Improving Outcomes for Low-Income Mothers With Depression
This is a randomized comparative effectiveness trial to improve outcomes among pregnant and post-partum women with symptoms of depression.
- Trial name
- NCT03221556
- Testing
- Engagement-Focused Care Coordination (EFCC), Problem Solving Education (PSE)
- Where
- United States
- Volunteers
- 231 people
- Sponsor
- Boston Medical Center
Depression, Self-regulation
Building Regulation in Dual Generations
Families who experience maternal mental illness and a variety of chronic stressors are currently underserved by the parenting programs.
- Conditions
- Depression, Self-regulation, Child Development
- Trial name
- BRIDGE (NCT04347707)
- Testing
- BRIDGE Therapy Program
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Mother-child Relationship Disturbances
Mother-Infant Psychoanalysis Project of Stockholm (MIPPS)- Follow-up at 4½ Years
An RCT comparing mother-infant psychoanalytic treatment (MIP) with Child Health Centre care in cases of mother-infant relationship disturbances was performed on 80 cases in Stockholm 2005-2008.
- Trial name
- MIPPS-02 (NCT01087112)
- Testing
- Mother-Infant Psychoanalytic tmt, Child Health Centre care
- Where
- Sweden
- Volunteers
- 71 people
- Sponsor
- Karolinska Institutet