Clinical trials: Mastitis
Granulomatous Mastitis
Ductal Lavage Versus Corticosteroids Therapy for Idiopathic Granulomatous Mastitis
A single-arm, proof-of-concept trial has shown the safety and efficacy of ductal lavage as a treatment for idiopathic granulomatous mastitis patients (Manuscript accepted in Journal of Surgical Research 2018).
- Trial name
- NCT03724903
- Testing
- Ductal lavage, Corticosteroid therapy
- Where
- 2 sites in China
- Volunteers
- 140 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Mastitis
Ductal Lavage in Non-lactating Female Women With Mastitis
RATIONALE and PURPOSE: For non-lactational mastitis patients pathologically diagnosis of idiopathic granulomatous mastitis (IGM) or periductal mastitis (PD), the investigators hypothesized that ductal lavage is able to relieve…
- Trial name
- NCT02794688
- Testing
- Ductal lavage therapy
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Idiopathic Granulomatous Mastitis, Granulomatous Mastitis
GRAnulomatous MAstitis REGistry Study
Idiopathic granulomatous mastitis (IGM) is a rare benign inflammatory breast condition with unknown cause, affecting approximately 2.4 per 100,000 women aged 20-40 years.
- Trial name
- GRAMAREG (NCT07422870)
- Where
- 2 sites in Germany
- Volunteers
- 1,000 people
- Sponsor
- European Breast Cancer Research Association of Surgical Trialists
Granulomatous Mastitis
Immune Cells in Patients With Granulomatous Mastitis
Granulomatous mastitis is a rare, chronic, benign inflammatory disease of the breast that plays a role in many varying etiologies, including infectious and non-infectious causes.
- Trial name
- NCT04543149
- Testing
- Flow cytometric immunophenotyping
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Idiopathic Granulomatous Mastitis
Idiopathic Granulomatous Mastitis
Assessment of incidence, diagnosis and treatment of idiopathic granulomatous mastitis in Assiut university hospital
- Trial name
- IGM (NCT04424615)
- Volunteers
- 30 people
- Sponsor
- Assiut University
Idiopathic Granulomatous Mastitis
Comparing Effectiveness of Steroids and Methotrexate in Treatment of Chronic Inflammatory Breast Disease
This research study is to determine the effectiveness of prednisolone and methotrexate for IGM patients over a period of one year, in terms of clinical and radiological response.
- Trial name
- IGM (NCT06943482)
- Testing
- Prednisolone, Methotrexate, Folic Acid 5 MG
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- National University Hospital, Singapore
Mastitis
Global Effects of a Probiotic Strain on Lactating Women
In this study, the investigators will try to confirm if application of probiotic strains isolated from breast milk actually have a beneficial effect on women suffering lactational mastitis.
- Trial name
- PROBIOLAC (NCT01124448)
- Testing
- Lactobacillus salivarius PS2
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Granulomatous Mastitis, Mastitis Chronic
Validity and Reliability of the Mastitis Symptom Severity Assessment Methods (M-Score and BISSI) in Non-Lactational Mastitis
The purpose of this study is to evaluate the validity and reliability of the Mastitis-score (M-score) and the Breast Inflammatory Symptom Severity Index (BISSI) as measures for assessing symptom severity in non-lactational…
- Trial name
- NCT06667609
- Testing
- Any treatments regimen
- Where
- 5 sites in China
- Volunteers
- 320 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Mastitis
Physical Therapy Intervention for Puerperal Mastitis
Puerperal mastitis is one of the most commonly reported problems during breastfeeding. Women frequently report breast pain, tenderness, redness, engorgement, fever, malaise, chills, lethargy, sweating, headache, nipple damage and…
- Trial name
- NCT04569136
- Testing
- Education, Therapeutic ultrasound, Breast massage
- Where
- Taiwan
- Volunteers
- 37 people
- Sponsor
- National Cheng Kung University
Mastitis
Osteopathic Manipulative Treatment for Recurrent Mastitis
This study will investigate whether Osteopathic Manipulative Treatment (OMT) is effective in treating recurrent mastitis without the use of antibiotics and if it helps in preventing future recurrence of mastitis in individuals…
- Trial name
- NCT05132426
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Sponsor
- Western University of Health Sciences
Refractory Granulomatous Lobular Mastitis
Surgical Intervention for Refractory Granulomatous Lobular Mastitis
Granulomatous lobular mastitis (GLM) belongs to a group of benign diseases, which is mainly treated with glucocorticoids and surgical treatment.
- Trial name
- NCT04637711
- Testing
- Focus clearing + whole breast exploration and washing + one-stage micro plastic surgery No Intervention: Extensive lesion excision
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Wuhan University
Mastitis, Staphylococcus Aureus
Staphylococcus Aureus Carrier Status in Breastfeeding Mothers and Infants and the Risk of Lactation Mastitis
Lactation (breastfeeding) mastitis is an acute infection of the milk ducts of the breastfeeding woman. Staphylococcus aureus (S. aureus) is the infectious germ most commonly associated with lactation mastitis.
- Conditions
- Mastitis, Staphylococcus Aureus, Staphylococcal Infections
- Trial name
- NCT00620984
- Where
- United States
- Volunteers
- 557 people
- Sponsor
- State University of New York - Upstate Medical University
Breast Infection
Outcomes of a Novel Technique of Mini- Incision and Self-Express (MISE) for Breast Abscess
Conventional techniques for treatment of breast abscess, such as incision and drainage/percutaneous drainage, have disadvantages. Bedside Mini-Incision and Self-Express (MISE) is a novel technique for breast abscess.
- Trial name
- NCT05762016
- Testing
- Bedside Mini-Incision and Self-Express (MISE)
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- KK Women's and Children's Hospital
Breast-conserving Plastic Surgery, Granulomatous Mastitis
Effect of Different Surgical Approaches of Granulomatous Mastitis
The objective of this study was to prospectively investigate the effects of different surgical approaches on the recurrence rate and aesthetic outcome of patients with granulomatous mastitis.
- Trial name
- NCT06712524
- Testing
- Breast-conserving plastic surgery, Traditional breast surgery
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Hubei Cancer Hospital
Mastitis Chronic, Idiopathic Granulomatous Mastitis
Baricitinib in Idiopathic Granulomatous Mastitis
This study will explore the mechanism of targeted drug in treatment of idiopathic granulomatous mastitis, and clarify the clinical classification and corresponding markers.
- Trial name
- B-IGM (NCT05852171)
- Testing
- Baricitinib
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Breast Feeding, Mastitis
Identification of Biomarkers of Mastitis
Breastfeeding is the optimal feeding for infants. WHO currently promotes breastfeeding and recommends it to be exclusive until the baby is 6 months old.
- Conditions
- Breast Feeding, Mastitis, Mastitis Acute Female
- Trial name
- NCT05021042
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- LactApp Women's Health
Mastitis Acute Female
The Effect of Chinese Herbal Medicine for Reducing the Application of Antibiotics in the Treatment of Acute Mastitis
The object of the study is to evaluate the effect of Pugongying (Herba Taraxaci) Granules to reduce the application of antibiotics for women with acute mastitis.
- Trial name
- NCT03756324
- Testing
- CHPM (Chinese Herbal Patent Medicine ), Antibiotics Cefdinir Capsules, Education
- Where
- 3 sites in China
- Volunteers
- 306 people
- Sponsor
- Beijing University of Chinese Medicine
Granulomatous Mastitis
Antibiotics vs Corticosteroids in Treatment of Granulomatous Lobular Mastitis
The goal of this clinical trial is to find the most effective and safe medical treatment for Granulomatous Lobular Mastitis (GLM) - a rare, chronic inflammatory breast disease that affects young and middle-aged women, often…
- Trial name
- GRANMAS (NCT07454772)
- Testing
- Steroid, Antibiotic
- Where
- India
- Volunteers
- 72 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Postpartum Complication
IMPACT: Improving Maternal Postpartum Access to Care Through Telemedicine
The purpose of this study is to compare two complex, multi-component evidence-based postpartum interventions in underserved populations of lower socioeconomic status in an effort to reduce maternal morbidity and mortality.
- Trial name
- IMPACT (NCT06218355)
- Testing
- Intensive Education, Enhanced Virtual Care
- Where
- 2 sites in United States
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Lactation Mastitis
The Effect of Gravity on the Occurrence of Lactational Mastitis
Lactation is the instinct of almost all mammals, including human beings. With the development of human society, the function of lactation has gradually deviated from nature instinct.
- Trial name
- NCT05207241
- Testing
- provides guidance on gravitationally assisted breastfeeding
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital