Clinical trials: Mastication
Hyperphosphatemia, Chronic Kidney Disease
Double Blind Randomized Placebo Controlled Trial of FOSTRAP Chewing Gum in Patients With CKD and Hyperphosphatemia
The phosphorus content in saliva is increased in chronic kidney disease. We hypothesize that a chewing gum that binds salivary phosphorus would be a novel, effective agent to reduce serum levels of phosphorus in patients with…
- Trial name
- NCT01057108
- Testing
- FOSTRAP Chewing Gum
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Denver Nephrologists, P.C.
Obesity, Overweight
Availability of Lipids in Almonds in Healthy Individuals
Evidence indicates that almond consumption is associated with multiple health benefits. However, nuts are commonly excluded from diets on the basis that their high energy content may induce weight gain.
- Trial name
- NCT00768417
- Testing
- 10 chews, 25 Chews, 40 Chews
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Chronic Kidney Disease
Phosphate Binding of Chitosan Chewing Gum in Patients With Chronic Kidney Disease (CKD)
To determine the amount of phosphate recovered into 2 strengths of K2CG chewing gum in a modified formulation (with or without an extender) added to the gum core, in comparison to matching placebo gums.
- Trial name
- NCT01341691
- Testing
- chewing gum
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Denver Nephrologists, P.C.
Dental Plaque, Saliva Altered
Effects of Two Sugar Substituted Chewing Gums on Caries and Gingivitis Variables
The purpose of this study is to determine the effect of three times a day mastication, during a follow-up period of 4 weeks, of two sugar-substituted chewing gums on various factors associated with dental caries and gingivitis.
- Conditions
- Dental Plaque, Saliva Altered, Gingivitis
- Trial name
- NCT01578603
- Testing
- xylitol, casein phosphopeptide amorphous calcium phosphate complex
- Where
- Colombia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Pain Associated With Fixed Orthodontic Treatment
Efficacy of Chewing Sugarless Gum for Reduction of Orthodontic Appliance Pain
This study investigates whether chewing sugar-free chewing gum can reduce pain associated with braces treatment. The study collects pain scale records for 10 consecutive days after placement of braces.
- Trial name
- NCT02024139
- Testing
- Chewing Sugarless Gum, Using Mouthwash
- Where
- Kuwait
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Bacterial Infections
Effect of Xylitol on Oral Microbiota in Children
1. The present controlled, randomized, doubleblind study aims to answer the following questions: How will the "normal flora" be affected by the xylitol consumption? Will daily consumption of xylitol change the plaque-saliva…
- Trial name
- NCT01528969
- Testing
- xylitol, sorbitol
- Where
- Kuwait
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Bowel Ileus, Flatus
Chewing Gum on Postoperative Ileus in Children
Traditional postoperative care has been challenged recently to improve and speedup recovery (including the return of bowel function) such that patients can be discharged to home more quickly.
- Trial name
- GUM_1 (NCT03666377)
- Testing
- Gum chewing
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Postoperative Ileus
Influence of Gum Chewing on Postoperative Bowel Activity After Complete Staging Surgery for Gynecological Malignancies
Postoperative ileus can cause the accumulation of secretions and gas, resulting in nausea, vomiting and abdominal distension and pain.
- Trial name
- NCT01835119
- Testing
- gum
- Where
- Turkey (Türkiye)
- Volunteers
- 152 people
- Sponsor
- Erzincan Military Hospital
Oral Processing Behavior, Mastication
Oral Processing Behavior of Gluten-free and Gluten-containing Breads
To attend the increasing demand for gluten-free products, new gluten-free formulations emerged in the market containing alternative ingredients to mimic the protein functionality of wheat.
- Conditions
- Oral Processing Behavior, Mastication, Swallowing
- Trial name
- NCT04671277
- Testing
- Chewing of breads
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Udine
Hunger
A Study of Chewing Gum, Snacking and Appetite
Investigators are interested in learning how appetite responds after chewing gum. In this research study subjects will be asked to eat a lunch meal provided at our Center.
- Trial name
- GUM (NCT01316991)
- Testing
- Chewing Gum, No Gum
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Temporomandibular Joint Disorders, Mastication Disorder
Altered MAstication Contribute to TMJ PAin
The cause of temporomandibular joint disorders remains unknown. It is considered multifactorial and includes physical (peripheral) and psychosocial (central) factors.
- Trial name
- MAPA (NCT03139994)
- Testing
- Diagnostic
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
End Stage Renal Disease
Chitosan Chewing Gum Study in Dialysis Patients
The purpose of the pilot study is to determine the impact of short-term administration of chitosan-containing chewing gum on phosphate levels in patients with elevated serum phosphate levels.
- Trial name
- NCT01770470
- Testing
- Chitosan
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Maryland, Baltimore
Nutritional and Metabolic Diseases
FaibaLite - Reduce Weight, One Bite at a Time
This study aims to evaluate the suitability of a fiber-enriched chewing gum as a practical and accessible approach to support healthy body weight management.
- Trial name
- NCT07045766
- Testing
- FibreGum chewing gum
- Sponsor
- University of Bern
Colon Cancer Screening
Impact of Chewing Gum on Bowel Preparation in Patients Undergoing Colonoscopy
Colorectal cancer is the second leading cause of cancer deaths that could be prevented in the United States. Colonoscopy is the best test for finding and removing polyps before they turn into cancer.
- Trial name
- NCT07320989
- Testing
- Chewing Sugar-Free Gum During Bowel Preparation, Standard Bowel Prep (2L PEG-ELP), Standard Bowel Prep
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Maryland, Baltimore
Caries Involving Multiple Surfaces of Tooth, Dental Caries on Chewing Surface of Tooth
The Survival Rate of Glass Ionomer Cement, Glass Carbomer Cement and Compomer in Occlusal and Proximal ART Restorations
The null hypothesis of this study is that GCC, GIC and compomer have the same survival rate when used for the treatment of occlusal and proximal caries in primary molars with ART under field conditions.
- Conditions
- Caries Involving Multiple Surfaces of Tooth, Dental Caries on Chewing Surface of Tooth, Dental Caries Extending Into Dentine
- Trial name
- ARTUSP (NCT02217098)
- Testing
- GIC Restorations, Carbomer Restorations, Compomer Restorations
- Where
- Brazil
- Volunteers
- 530 people
- Sponsor
- Daniela Prócida Raggio
Dental Plaque, Dental Caries
Development of a Novel Anti-caries Chewing Gum
This research study is designed to evaluate the chewing gum's ability to modulate the oral microbiome in human participants, in addition to its safety.
- Conditions
- Dental Plaque, Dental Caries, Periodontal Disease
- Trial name
- NCT05946473
- Testing
- Gum base containing xylitol and essencial oils, Gum base with no additives
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Subjects, Smokers
4 mg Nicotine Polacrilex Gum and Swedish Portion Snus
Fifteen healthy smokers are given single doses of General Onyx 1 g portion snus and General White 1g portion snus, respectively, and one piece of Nicorette 4 mg chewing gum.
- Trial name
- SMWS06 (NCT01182129)
- Testing
- Nicotine
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Contract Research Organization el AB
Postoperative Ileus
Effects of Chewing Gum Against Postoperative Ileus
The purpose of this study is to determine whether the use of chewing gum effects postoperative ileus after pancreaticoduodenectomy.
- Trial name
- NCT02319512
- Testing
- Chewing gum, Glucose
- Volunteers
- 65 people
- Sponsor
- Thomas Andersson
Colonoscopy, Bowel Preparation
Effect of Gum Chewing or Walking on Bowel Prep Quality and Patient Satisfaction Before Colonoscopy
Colorectal cancers are a major global health problem, highlighting the critical importance of screening programs for early diagnosis and effective treatment.
- Trial name
- NCT06192394
- Testing
- Chewing Gum, Walking Exercise, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Istanbul University - Cerrahpasa
Non-sarcopenic Subjects, Possible Sarcopenia
Study on the Effect of Edible Mastication Training Colloid Intervention of Oral Muscle Training in Patients of Sarcopenia
The main purpose of this study is to screen middle-aged and elderly (≧ 45 years old) individuals at high risk of sarcopenia and sarcopenia, and to investigate whether sarcopenia can improve dental bite force and tongue pressure…
- Conditions
- Non-sarcopenic Subjects, Possible Sarcopenia, Sarcopenia (With Low ASM by BIM)
- Trial name
- EMTC-Sarc (NCT07658599)
- Testing
- oral muscle strength training
- Where
- Taiwan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology