Clinical trials: Mandibular Third Molar
Pain
Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1386
The primary aim of this study is to investigate if AZD1386 can relieve the pain induced by the surgical removal of one lower wisdom-tooth.
- Trial name
- NCT00672646
- Testing
- AZD1386, Naproxen
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Postoperative Pain, Facial Swelling
Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery
This randomized, single-blind, controlled clinical trial aims to evaluate the efficacy and safety of Aescin-based herbal extract (Reparil®) compared with Ibuprofen in managing postoperative sequelae following surgical removal of…
- Conditions
- Postoperative Pain, Facial Swelling, Trismus
- Trial name
- Reparil (NCT07244029)
- Testing
- Escin, Ibuprofen 400 mg
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Impacted Third Molar Tooth
Gum Health Gel in Post Extraction Sockets
This research studies the effectiveness of the Gum Health gel in minimizing post operative sequelae associated with the surgical removal of impacted mandibular third molars
- Trial name
- Gum Health gel (NCT06251141)
- Testing
- Gum Health gel, Gel foam
- Where
- Iraq
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Impacted Third Molar Tooth
Effects of Photobiomodulation Conditioning in Impacted Third Molars
The removal of third molars should be considered to avoid problems such as cysts and other complications. Surgical intervention with the manipulation of oral tissues has the undesirable postoperative effects of pain, trismus…
- Trial name
- NCT05344222
- Testing
- Infrared LED, Similar device - Infrared ED
- Where
- Brazil
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Periodontal; Lesion, Periodontal Pocket
Prevention of Mandibular Third Molar Extraction- Associated Periodontal Defects Using Platelet-Rich Fibrin
The extraction of deep impacted mandibular third molar may cause periodontal defects at the distal root of the second molar. The aim of this study was to evaluate the ability of platelet-rich fibrin (PRF) in preventing…
- Conditions
- Periodontal; Lesion, Periodontal Pocket, Molar, Third
- Trial name
- NCT04033744
- Testing
- extraction of mandibular third molar
- Where
- Italy
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Naples
Mastication Disorder
Evaluation of Platelet Rich Fibrin on Reduction of Periodontal Problems After Surgical Removal of Mandibular Third Molar
The purpose of this study is to determine the influence of platelet rich fibrin to reduction of periodontal problems after surgical removal of third molar.
- Trial name
- NCT01583491
- Testing
- autologous platlet rich fibrin, one side in control group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Majid Eshghpour
Impacted Third Molar Tooth
Comperasion the Postoperative Effect of Low Laser Therapy and Platelet Rich Fibrin on Mandibular Third Molar Surgery.
The aim of this study was investigate the comparison of postoperative effects of low laser treatment and platelet-rich fibrin application on mandibular impacted third molar tooth extraction.
- Trial name
- NCT06262945
- Testing
- Diagnoses, traditional osteotomies, platelet rich fibrin
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beste Erismen
Impacted Third Molar Tooth
Comparison of The Surgical Drain Placement With Use of Kinesiologic Tape
The investigator's purpose was to compare the effects of the surgical drain and kinesiologic tape applications on postoperative morbidity after mandibular third molar surgery.
- Trial name
- NCT04108559
- Testing
- Kinesiologic Tape Group, Drain Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Extraction of Third Molar Teeth
Perioperative Acupuncture for Impacted Mandibular Third Molar Extractions
This is a double-blinded, randomized, controlled study on the effect of perioperative acupuncture on pain after third molar extraction.
- Trial name
- NCT02498184
- Testing
- acupuncture
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Third Molars Extraction
Avatar-assisted Pre- and Post-operative Information Following Surgical Removal of a Mandibular Third Molar.
This study assess the efficacy of digital avatar-assisted pre- and post-operative information against nurse-led oral and written information following SRM3 including an analysis of potential risk factors associated with impaired…
- Trial name
- NCT07805304
- Testing
- Avatar-assisted pre- and post-operative information following surgical removal of an mandibular third molar
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Impacted Mandibular Third Molar
Does Vitamin C Improve Postoperative Healing
This randomized, split-mouth clinical trial investigates the effect of oral vitamin C supplementation on postoperative recovery following the surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07012564
- Testing
- Vitamin C
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Impacted Mandibular Third Molar, Alveolar Bone Loss
Healing of Mandibular Third Molar Extraction Sockets Using Platelet Concentrates and Photobiomodulation
Surgical removal of impacted mandibular third molars is a common procedure that may be associated with postoperative pain, swelling, limited mouth opening, and delayed bone healing.
- Conditions
- Impacted Mandibular Third Molar, Alveolar Bone Loss, Impacted Mandibular Third Molar Extraction
- Trial name
- NCT07324213
- Testing
- Mandibular Third Molar Extraction With Primary Wound Closure, Autologous Platelet Concentrates, Photobiomodulation
- Where
- Poland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw
Oral Health
Effect of Hypochlorous Acid-containing Mouthwash on Healing After Impacted Wisdom Tooth Surgery
INTRODUCTION: Local chemotherapeutic agents are used to reduce inflammation after impacted tooth extraction and to minimize possible complications, as well as to increase patient comfort.
- Trial name
- Mouthwash (NCT06920485)
- Testing
- Third molar surgery, Pain Medicine, Wound healing
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Pain
Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1940
The primary aim of this study is to investigate if AZD1940 can relieve the pain induced by the surgical removal of one lower wisdom-tooth.
- Trial name
- NCT00659490
- Testing
- AZD1940, Naproxen
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Third Molar Extraction
The Safety and Efficacy of Alveolar Bone Defect Repair Induced by Gelatin Sponge-loaded Apoptotic Vesicle Complex
Distal bone loss of the second molar due to extraction of the third molar is one of the most common pathological conditions that results in tooth loss of second molar.
- Trial name
- NCT05971342
- Testing
- Gelatin sponge-loaded apoptotic vesicle complex（Kuaikang®), Gelatin sponge only （Kuaikang®)
- Where
- China
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Fifth Affiliated Hospital of Guangzhou Medical University
Tooth Displacement
Retrieval of Displaced Mandibular Third Molar Teeth
The aim of this study is to compare multi-detector CT and CBCT as pre-surgical diagnostic imaging before surgical retrieval of iatrogenic displaced mandibular third molar teeth/roots.
- Trial name
- NCT06060522
- Testing
- CT, CBCT
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tanta University
Impacted Third Molar Tooth
Effectiveness of Platelet Rich Plasma in Wound Healing
Purpose: This prospective randomized comparative clinical study was conducted to assess the effect of platelet-rich plasma (PRP) gel on soft tissue healing and bone regeneration potential on lower third molar extraction sockets.
- Trial name
- NCT02831374
- Testing
- Local anesthesia, surgical extraction of impacted third molar, Preparation of PRP gel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Linyi People's Hospital
As a Decision-support Tool During Preoperative Assessment
Accuracy of AI in Positional Classification Between Lower Third Molar and Mandibular Canal
This study will be performed to develop and validate an artificial intelligence model for automatic positional assessment of mandibular third molars relative to the mandibular canal on panoramic radiographs
- Trial name
- AI (NCT07918651)
- Volunteers
- 631 people, healthy volunteers welcome
- Sponsor
- Roshan Adel Ahmed Elsayed
Third Molar Surgery
A-PRF AND HA AFTER IMPACTED THIRD MOLAR SURGERY
This randomized controlled clinical trial evaluated the effects of advanced platelet-rich fibrin (A-PRF) and hyaluronic acid (HA) on healing after surgical removal of impacted mandibular third molars.
- Trial name
- NCT07835373
- Testing
- Advanced Platelet-Rich Fibrin, Sodium hyaluronate
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Inonu University
Stem Cell, Third Molar
Effect of Dental Pulp Stem Cells and L-PRF After Impacted Third Molar Extraction
The purpose of this study is to compare the clinical and radiographic effectiveness of Leukocyte-Platelet Rich Fibrin (L-PRF) and L-PRF combined with dental pulp stem cell (DPSC) application to the extraction socket of mandibular…
- Conditions
- Stem Cell, Third Molar, Periodontal Pocket
- Trial name
- NCT04641533
- Testing
- L-PRF + DPSC, L-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Baskent University