As a Decision-support Tool During Preoperative AssessmentAINCT07918651
Accuracy of AI in Positional Classification Between Lower Third Molar and Mandibular Canal
An observational study of As a Decision-support Tool During Preoperative Assessment, run by Roshan Adel Ahmed Elsayed.
Trial summary
This study will be performed to develop and validate an artificial intelligence model for automatic positional assessment of mandibular third molars relative to the mandibular canal on panoramic radiographs Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- As a Decision-support Tool During Preoperative Assessment
- How many people
- 631 participants
- Where
- No sites listed yet
- Study dates
- 1 Jan 2027to 30 Jul 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: All Panoramic images with adequate image quality without significant artifacts of patients who are with minimum age of 18 years and have at least one mandibular third molar.
Who may be able to join
- Patients aged 18 years or older.
- Presence of at least one mandibular third molar.
- Panoramic images with adequate image quality without significant artifacts
Who cannot join
- Poor-quality radiographs.
- Motion artifacts.
- Incomplete visualization of the mandibular canal.
- Extensive pathology affecting the region of interest.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Accuracy of Artificial Intelligence in the Positional Assessment of Lower Third Molar in Relation to the Mandibular Canal Using Panoramic Radiography: Observational Cross Sectional Study
This study will be performed to develop and validate an artificial intelligence model for automatic positional assessment of mandibular third molars relative to the mandibular canal on panoramic radiographs
- Keywords
- AI, Mandibular canal and mandibular third molar relation
What is being measured
The primary outcome is the main question the study is designed to answer.
Detection of positional relationship between Mandibular third molar and Mandibular canal
Measured: 5 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Nov 2026
- Study start1 Jan 2027 (estimated)
- Primary completion30 May 2027 (estimated)
- Study completion30 Jul 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for As a Decision-support Tool During Preoperative AssessmentStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 631 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Roshan Adel Ahmed Elsayed
- Sponsor type
- University, hospital or other
- Collaborators
- Misr University for Science and Technology
- Responsible party
- Sponsor-investigator, Roshan Adel Ahmed Elsayed, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07918651
- Sponsor's protocol ID
- ORAD-AI-CU-2026
- Acronym
- AI
- Status last verified
- Oct 2026
- First submitted
- 30 Oct 2026
- Last updated
- 5 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Kempers S, van Lierop P, Hsu TH, Moin DA, Berge S, Ghaeminia H, Xi T, Vinayahalingam S. Positional assessment of lower third molar and mandibular canal using explainable artificial intelligence. J Dent. 2023 Jun;133:104519. doi: 10.1016/j.jdent.2023.104519. Epub 2023 Apr 13.
PubMed 37061117
Study at a glance
From the registry record, last updated by the sponsor on 5 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Accuracy of Artificial Intelligence in the Positional Assessment of Lower Third Molar in Relation to the Mandibular Canal Using Panoramic Radiography: Observational Cross Sectional Study
- ClinicalTrials.gov ID
- NCT07918651
- Acronym / sponsor ID
- AI / ORAD-AI-CU-2026
- Keywords
- AI, Mandibular canal and mandibular third molar relation
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 631 participants (estimated)
- Lead sponsor
- Roshan Adel Ahmed ElsayedUniversity, hospital or other
- Collaborators
- Misr University for Science and Technology
- Study start
- 1 Jan 2027 (estimated)
- Primary completion
- 30 May 2027 (estimated)
- Study completion
- 30 Jul 2027 (estimated)
- First posted
- 5 Nov 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will be performed to develop and validate an artificial intelligence model for automatic positional assessment of mandibular third molars relative to the mandibular canal on panoramic radiographs
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- All Panoramic images with adequate image quality without significant artifacts of patients who are with minimum age of 18 years and have at least one mandibular third molar.
Key inclusion criteria (3 listed)
- Patients aged 18 years or older.
- Presence of at least one mandibular third molar.
- Panoramic images with adequate image quality without significant artifacts
Key exclusion criteria (4 listed)
- Poor-quality radiographs.
- Motion artifacts.
- Incomplete visualization of the mandibular canal.
- Extensive pathology affecting the region of interest.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Detection of positional relationship between Mandibular third molar and Mandibular canal
Time frame: 5 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Nov 2026.
- Results publication: PubMed 37061117Kempers S, van Lierop P, Hsu TH, Moin DA, Berge S, Ghaeminia H, Xi T, Vinayahalingam S. Positional assessment of lower third molar and mandibular canal using explainable artificial intelligence. J Dent. 2023 Jun;133:104519. doi: 10.1016/j.jdent.2023.104519. Epub 2023 Apr 13.
- Individual participant dataSharing planned: Undecided
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
An observational study of As a Decision-support Tool During Preoperative Assessment, run by Roshan Adel Ahmed Elsayed.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 5 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Roshan Adel Ahmed, Assistant lecturer (01152925888, roshan.ahmed@dentistry.cu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Detection of positional relationship between Mandibular third molar and Mandibular canal (time frame: 5 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07918651, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Nov 2026; AzTrials last refreshed its copy on 6 Nov 2026.