Clinical trials: Malrotation
Congenital Disorders
Racial Distribution of Heterotaxy Syndrome
Heterotaxy syndrome is a heterogeneous disease that is the result of a failure of normal right-left lateralization of the abdominal and thoracic organs during development.
- Trial name
- NCT00485654
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Children's Healthcare of Atlanta
Postnatal Complication, Mesenteric Pregnancy
Prenatal Screening of Intestinal Malrotation With a Higher Risk of Volvulus.
Digestive malrotation is an anatomical anomaly of the positionning of the mesenteric vessels and the digestive tract that can lead in some form to a dangerous neonatal complication: intestinal volvulus.
- Trial name
- MALROT (NCT05148429)
- Testing
- Ultrasound exam, Fetal MRI, Postnatal abdominal ultrasound
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Necrotizing Enterocolitis, Intestinal Atresia
Pattern And Outcome Of Neonatal Gastrointestinal Emergencies In Assiut University Children Hospital
This prospective observational study aims to evaluate the pattern, clinical presentation, complications, and short-term outcomes of neonates admitted with gastrointestinal emergencies to the NICU at Assiut University Children…
- Conditions
- Necrotizing Enterocolitis, Intestinal Atresia, Malrotation, Hirschsprung Disease
- Trial name
- NCT07526636
- Volunteers
- 120 people
- Sponsor
- Assiut University
Pregnancy Related
Diagnostic Performance of Antenatal Ultrasound for High-Risk Intestinal Malrotation
The aims of this study are: To assess the performance of third-trimester ultrasound scan in the localization of intestinal structures (small bowel, gut, mesenteric vessels..) involved in malrotations with a higher-risk of…
- Trial name
- MALGRE (NCT03968107)
- Testing
- Reference ultrasound examination
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Interna Rotation Gait, Cerebral Palsy
Controlling Femoral Derotation Osteotomy With Electromagnetic Tracking
The study is designed to evaluate the use of electromagnetic tracking in femoral derotation osteotomies. The goal is to raise the precision of the surgical procedure in order to improve the outcome in short- and long term.
- Conditions
- Interna Rotation Gait, Cerebral Palsy, Malrotation; Bone, In-toing
- Trial name
- NCT02976532
- Testing
- Electromagnetic tracking unit in femoral derotation surgery
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Heidelberg University
NEC, Atresia
Safety and Feasibility of Indocyanine Green Fluorescence for Intraoperative Assessment of Intestinal Perfusion in Young Infants and Neonates
The goal of this clinical trial is to test the use of the SPY-PHI device for the purpose of ICG-mediated intestinal perfusion visualization during gastrointestinal surgery in neonates and young infants (<3 months old) undergoing…
- Conditions
- NEC, Atresia, Malrotation, Intestinal Perforation
- Trial name
- IMAGINE (NCT05734118)
- Testing
- Perfusion assessment by means of the SPY-PHI camera
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
Fetal Volvulus, Midgut Volvulus
Prenatal Diagnosis of Antenatal Midgut Volvulus: Specific Ultrasound Features
Objective: The small bowel volvulus is a rare cause of intestinal obstruction which may occur in utero and whose prenatal diagnosis is difficult.Sonographic signs are mainly indirect and non specific.The aim of this study is to…
- Trial name
- NCT03362450
- Testing
- Fetal ultrasound during the second or third trimester/ Postnatal surgery / Post mortem examination
- Where
- France
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Metacarpal Shaft Fractures
Swelling or Malrotation of Metacarpal Shaft Fractures in the Evaluation of Rotational Deformity
Rotational deformity or malunion causes the most significant functional deficit in these common fractures. The evaluation of the rotation may be performed with the metacarpophalangeal joints flexed although postoperative swelling…
- Trial name
- NCT00934869
- Where
- 2 sites in Israel
- Sponsor
- Hadassah Medical Organization
Singleton-Merten Syndrome, Postnatal Complication
Prenatal US Assessment of Superior Mesenteric Vessels for Digestive Rotation
Digestive malrotation is an anatomical anomaly of the positionning of the mesenteric vessels and the digestive tract that can lead in some form to a dangerous neonatal complication: intestinal volvulus.
- Trial name
- SMA (NCT05204771)
- Testing
- Ultrasound exam, Postnatal abdominal ultrasound, Pediatric Follow up
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Heterotaxy Syndrome, Congenital Heart Defects
Molecular Genetics of Heterotaxy and Related Congenital Heart Defects
The goal of this study is to obtain specimens and data from individuals and their families with heterotaxy and related congenital heart defects in order to clarify the molecular genetics of this disorder.
- Trial name
- NCT02432079
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Indiana University
Sacroiliac Strain, Low Back Pain
Correction of Low Back Pain From Sacroiliac Malrotation With a Simple in Home Exercise
60 participants with low back pain will be examined to determine the direction and extent of sacroiliac malrotation. If malrotation exists, they will be randomized to 3 treatment groups: 1 will be taught how to use their thigh to…
- Trial name
- SIbackpain (NCT03888235)
- Testing
- Immediate corrective exercises, Immediate use of pelvic support belt, Delayed treatment
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Intestinal Malrotation
Prenatal Ultrasound Screening of Intestinal Malrotation With a Higher Risk of Volvulus
The aim of this study was to assess the value of an unusual relative position of the superior mesenteric artery (SMA) and vein (SMV) to screen intestinal malrotation with a higher risk of volvulus.
- Trial name
- VOLMES (NCT03356314)
- Testing
- MRI between 30-35 GA, Pediatric surgeon meeting, Postnatal abdominal ultrasound, barium enema and upper gastrointestinal
- Where
- France
- Volunteers
- 9,000 people
- Sponsor
- University Hospital, Montpellier
Gastrointestinal Complication, Intestinal Obstruction
The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies
This study explores the use of an exclusive human milk diet versus standard feeding practices to compare the influence on feeding outcomes and the gut bacteria in infants with intestinal differences.
- Conditions
- Gastrointestinal Complication, Intestinal Obstruction, Gastroschisis, Hirschsprung Disease
- Trial name
- NCT06072976
- Testing
- Standard of Care, Exclusive Human Milk
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Seattle Children's Hospital
Heterotaxy Syndrome
Heterotaxy Syndrome and Intestinal Rotation Abnormalities - A Prospective Study
Infants with heterotaxy syndrome (HS) are born with an abnormal arrangement of organs along the right-left body axis. Abnormalities of intestinal rotation and fixation are commonly associated with HS.
- Trial name
- NCT01591928
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Endourology, Stones, Kidney
Flexible URS in Management of Renal Stones in Anomalous Kidney
The urotheliasis is a common problem encountered daily by all urologists worldwide with rates up to 13% in North America, 9% in Europe and 5% in Asia .
- Conditions
- Endourology, Stones, Kidney, Laser, Congenital Disorders
- Trial name
- NCT05299996
- Testing
- flexible ureterorenoscopy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Intestinal Atresia, Necrotizing Enterocolitis
The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery.
Background: Intestinal resections are commonly performed in the pediatric population. Perfusion of the bowel is one of the most important factors determining the viability of an intestinal anastomosis.
- Conditions
- Intestinal Atresia, Necrotizing Enterocolitis, Hirschsprung Disease, Gastroschisis
- Trial name
- NCT04020939
- Testing
- SPY imaging, Indocyanine Green
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Knee Osteoarthritis
Using Intraoperative Sensing Technology to Evaluate Revision Total Knee Arthroplasty
This study will attempt to draw relationships between the soft-tissue related complications contributing to early TKA revision and the loading and positional patterns from intraoperative tibial trial sensors.
- Trial name
- NCT03023410
- Testing
- VERASENSE
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Orthosensor, Inc.