Clinical trials: Malocclusion Class II, open to volunteers
Class II Malocclusion, Class II Malocclusion, Division 1
Comparison of Early Interceptive Orthodontic Appliances (Traditional and Novel) and Later Fixed Appliance Treatment in Class II Malocclusion.
Background Approximately 15% of children have a Class II malocclusion, where the maxilla is positioned anterior to the mandible, and around 90% of these children also present with an increased overjet.
- Conditions
- Class II Malocclusion, Class II Malocclusion, Division 1, Overjet
- Trial name
- MACTWin (NCT07404696)
- Testing
- Head gear activator, Twin Block, Invisalign mandibular advancement
- Where
- 3 sites in Sweden
- Volunteers
- 144 people
- Sponsor
- Vastra Gotaland Region
Skeletal Class II Malocclusion, Skeletal Class III Malocclusion
Clinical and Radiographic Evaluation of Low Sagittal Medial Ramus Osteotomy for Treatment of Skeletal Class II and Class III Malocclusion
This prospective clinical trial aims to evaluate the clinical and radiographic outcomes of the low sagittal medial ramus osteotomy-a technical modification of the conventional sagittal split osteotomy (SSO)-for treating patients…
- Conditions
- Skeletal Class II Malocclusion, Skeletal Class III Malocclusion, Dentofacial Deformities
- Trial name
- NCT07746700
- Testing
- Low Sagittal Medial Ramus Osteotomy
- Volunteers
- 11 people
- Sponsor
- Al-Azhar University
Malocclusion, Class II Malocclusion
Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy
Patient with class ii division 1 malocclusion who have mild increased overjet will be treated in this study. The efficacy of clear aligners in the treatment of Class II division 1 Malocclusion Using Intermaxillary Elastics will…
- Trial name
- malocclusion (NCT05684510)
- Testing
- clear aligners, traditional treatment Fixed appliances with class II elastics.
- Where
- Syria
- Volunteers
- 24 people
- Sponsor
- Hama University
CLASS II DIVISION 1 MALOCCLUSION
Twin-Block and LIPUS for TMJ Outcomes in Skeletal Class II Patients
Evaluation of the efficacy of early treatment of skeletal class II patients with twin-block in conjunction with low intensity pulsed ultrasound on temporomandibular joint region: a prospective clinical trial
- Trial name
- AlAzharU (NCT07676695)
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Class II Malocclusion
Maxillary Arch Distalization With Infrazygomatic Crest Miniscrews for Class II Malocclusion
This prospective clinical study will evaluate the effects of moving the entire upper dental arch backward using infrazygomatic crest miniscrews in participants with Class II malocclusion.
- Trial name
- NCT07875660
- Testing
- Infrazygomatic Crest Miniscrews
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Mansoura University
CLASS II DIVISION 1 MALOCCLUSION
EVALUATION OF TREATMENT CHANGES IN CLASS II DIVISION 1 MALOCCLUSION DURING EN MASSE RETRACTION OF UPPER ANTERIOR TEETH USING MINI IMPLANTS PLACED AT INFRAZYGOMATIC CREST AND INTERRADICULAR SITES A RANDOMIZED CLINICAL TRIAL.
Rationale: Class II Division 1 malocclusion is characterized by upper anterior teeth protrusion resulting in upper lip protrusion and convex facial profile, which are considered esthetically unfavorable.
- Trial name
- NCT07405905
- Testing
- retraction of anterior teeth using mini implants placed at infrazygomatic crest., retraction of anterior teeth using mini implants placed at interradicular sites.
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Malocclusion of Anterior Teeth, Malocclusion in Children
Patient-Reported Outcomes for Different Orthodontic Thermoplastics Used in Clear Aligners
Clear aligner therapy is an esthetic orthodontic treatment modality that uses removable thermoplastic trays to correct dental alignment.
- Conditions
- Malocclusion of Anterior Teeth, Malocclusion in Children, Malocclusion Class II
- Trial name
- NCT07790315
- Testing
- Device / orthodontic clear aligner material
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Class II Division 1 Adolescent Patients
Three-Dimensional Evaluation of Pharyngeal Airway and Facial Dimension Changes in Skeletal Class II Patients Treated With Twin Block Versus Myobrace Appliances
This study is intended primarily to compare the effects of two Class II correction appliances, namely Twin block and Myobrace appliances, on pharyngeal airway dimensions during the treatment of class II division 1 adolescent…
- Trial name
- NCT06976749
- Testing
- myobrace appliance, Twin block
- Where
- Iraq
- Volunteers
- 50 people
- Sponsor
- University of Baghdad
Malocclusion, Angle Class II, Overbite (Excessive) Horizontal
Long-term Stability of Treatment With the Twin Block Appliance
The objective of this observational study is to investigate the long-term stability of treatment with the Twin block appliance in a patient group previously treated with a Twin block appliance.
- Conditions
- Malocclusion, Angle Class II, Overbite (Excessive) Horizontal, Overbite (Excessive) Deep, Treatment Outcome
- Trial name
- NCT07752498
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Region Jönköping County
Malocclusion, Angle Class I, Malocclusion, Angle Class II
3D Printed Occlusal Splints for Intraoperative Use
A 3D printed intraoperative occlusal splint is a custom-made biocompatible resin guide that allows surgeons properly align a patient's upper and lower dentition during surgery.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- NCT07079111
- Testing
- Formlabs 3D printed occlusal splint, Industry made occlusal splint
- Volunteers
- 70 people
- Sponsor
- Johns Hopkins University
Malocclusion, Angle Class II, Malocclusion, Angle Class III
Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative Time
The purpose of this study is to find out if 3D printed patient-specific titanium plates improve surgical accuracy and decrease operative time compared to milled patient-specific titanium plates in patients having Le Fort I…
- Conditions
- Malocclusion, Angle Class II, Malocclusion, Angle Class III, Dentofacial Deformities, Osteotomy, Le Fort I
- Trial name
- TiPlateRCT (NCT07841067)
- Testing
- 3D-Printed Patient-Specific Titanium Plates, Milled Patient-Specific Titanium Plates
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Future University in Egypt
Orthodontic Appliances, Removable, Orthodontic Appliance Complication
Microbial Adherence, Surface Roughness, Effectiveness and Impact on Patients Between Conventional and 3D Printed Twin Block Appliances
The Twin Block appliance is a removable orthodontic appliance that is used to help correct a backward positioned lower jaw in growing children.
- Conditions
- Orthodontic Appliances, Removable, Orthodontic Appliance Complication, Class II Malocclusion, Division 1
- Trial name
- NCT06944860
- Testing
- Conventional TBA, 3D TBA
- Where
- Malaysia
- Volunteers
- 32 people
- Sponsor
- University of Malaya
Class II Malocclusion, Mandibular Advancement
Invisalign® System with Mandibular Advancement
The goal of this clinical trial is to observe study participants' comfort and fit of their aligners with occlusal blocks, as well as evaluate the engagement of the blocks using the Invisalign® System with mandibular advancement…
- Conditions
- Class II Malocclusion, Mandibular Advancement, Mandibular Retrognathism, Excessive Overjet
- Trial name
- NCT06651944
- Testing
- Invisalign® System with mandibular advancement featuring occlusal blocks
- Where
- 3 sites in Canada
- Volunteers
- 36 people
- Sponsor
- Align Technology, Inc.
Malocclusion, Angle Class II, Division 1, Bimaxillary Protrusion
LLLLT vs Piezocision in Accelerating Orthodontic Canine Retraction
This comparative controlled clinical study aims to evaluate and compare the effectiveness of piezocision and low-level laser therapy (LLLT) as adjunctive interventions to accelerate orthodontic canine retraction.
- Conditions
- Malocclusion, Angle Class II, Division 1, Bimaxillary Protrusion, Class I Malocclusion
- Trial name
- NCT07466641
- Testing
- Low Level Laser Therapy, Piezocision
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Hesham Nabil Ali Al-Qamhawy
Bite, Orthodontics
Evaluation of a Novel Lip Bumper With Integrated Distal Shoe Appliance in Preventing Second Molar Impaction in Children With Anterior Deep Bite
The goal of this clinical trial is to evaluate the effectiveness of a novel lip bumper with an integrated distal shoe in preventing second molar impaction in children aged 8-10 years with anterior open bite during the mixed…
- Trial name
- Novel Lip Bump (NCT07015385)
- Testing
- Lip Bumper with Integrated Distal Shoe, Conventional Lip Bumper
- Volunteers
- 40 people
- Sponsor
- Dar Al Uloom University
CLASS II DIVISION 1 MALOCCLUSION, Class II Malocclusion
The Effectiveness of the Twin Block and Carriere Motion Appliances in Post-pubertal Patients and an Evaluation of the Impact of Class II Malocclusion and Its Correction on Oral Health-related Quality of Life
The investigators of this clinical trial aim to: Compare the effectiveness and efficiency of Clark's Twin Block Appliance (CTB) vs Carriere Motion Appliance (CMA) in correcting Class II malocclusion when used in post-pubertal…
- Conditions
- CLASS II DIVISION 1 MALOCCLUSION, Class II Malocclusion, Growth, Overjet
- Trial name
- NCT07292636
- Testing
- CTB, CMA
- Where
- Ireland
- Volunteers
- 88 people
- Sponsor
- Aslam Alkadhimi
Bimaxillary Protrusion, Class II Div 1 Malocclusion
Discision as Acceleration Method in Canine Retraction in Orthodontics With Aligner and Fixed Appliances in Young Adults a Split Mouth Study
The effectiveness of discision in accelerating orthodontic canine retraction will be evaluated during clear aligner therapy and during conventional fixed orthodontic appliances.
- Trial name
- NCT07920276
- Testing
- Discision
- Where
- 2 sites in Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Mal Occlusion Class 2
Comparative Study Between Two 3D Functional Appliances Herbst and Mandibular Anterior Repositioning Appliance (MARA) on Posterior Airway Space And TMJ in Growing Class II Malocclusion Patients
The aim of this study is to evaluate effect of three dimensional printed appliances Herbst appliance and Mandibular Anterior Repositioning Appliance (MARA) on Posterior Airway Space (PAS) and Temporomandibular Joint (TMJ) in…
- Trial name
- NCT07094841
- Testing
- 3D PRINTED herbst appliance, 3d printed mara
- Volunteers
- 20 people
- Sponsor
- Moataz Sleem Ahmed Ali
Malocclusion Class II, Malocclusion, Angle Class I
Effect of Early Versus Late Premolar Extraction on Orthodontic Tooth Movement
The goal of this randomized controlled trial is to evaluate whether the timing of premolar extraction affects the rate of orthodontic space closure during en-masse anterior retraction.
- Trial name
- NCT07773389
- Testing
- Early Maxillary First Premolar Extraction, Late Maxillary First Premolar Extraction
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Shifa College of Dentistry
Class II Malocclusion, Mandibular Deficiency
Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II
Objective: to evaluate the dentoskeletal effects of CAD/CAM 3D-Printed fixed twin block versus MARA appliances in the management of skeletal class II due to Mandibular Deficiency in Preadolescence Class II malocclusion is…
- Trial name
- NCT07340242
- Testing
- MARA appliance, fixed twin block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University