Clinical trials: Malocclusion
Malocclusion
A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.
This is a three-armed, multicenter clinical study evaluating the SureSmile clear aligner medical device. The primary objective is to confirm the safety and assess the accuracy of different tooth movements.
- Trial name
- NCT07290790
- Testing
- SureSmile® Clear Aligners
- Where
- 6 sites in United States, Spain and 1 more
- Volunteers
- 90 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Dental Crowding, Malocclusion, Angle Class I
Treatment Outcome of Elastomeric and Nickel-Titanium Separators in Tooth Separation
Patients seeking fixed orthodontic treatment that requires band placement will be enrolled in this study. This trial aims to compare the efficiency of rectangular cross-section nickel-titanium separators with elastomeric…
- Trial name
- NCT07591454
- Testing
- Elastomeric separators, Nickel-Titanium separators
- Volunteers
- 30 people
- Sponsor
- 3D-Aligners
Malocclusion, Orthodontic Treatment
Impact of Photobiomodulation on Pain During Orthodontic Treatment.
The objective of this study is to determine to effect of PBM Ortho, a photobiomodulation device, in adult patients undergoing clear aligners orthodontic treatment.
- Trial name
- NCT05361616
- Testing
- PBM Ortho
- Where
- 2 sites in Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PBM Healing International Limited
Malocclusion, Clear Aligner Appliance
Impact of Aligner Replacement Protocols on Predictability of Planned Dental Movements: Evaluation of Double Aligner
The study will evaluate the impact of replacing aligners after 7 days with new aligners made of different materials on the predictability of planned dental movements.
- Conditions
- Malocclusion, Clear Aligner Appliance, Orthodontics, Tooth Movement
- Trial name
- NCT06882395
- Testing
- Group 1: FLX aligners for 10 days, Group 3: FLX aligners for 7 days, followed by new FLX aligners for 3 days., Group 2: FLX aligners worn for 7 days, followed by FLX35 aligners for 3 days.
- Where
- Brazil
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Neodent
Malocclusion, Tooth Movement Techniques
Efficacy of Orthodontic Tooth Movement Using Beveled and Conventional Attachments in Aligners
The objective of this study is to evaluate the efficacy of tooth movement using beveled attachments and conventional attachments.
- Trial name
- NCT06873932
- Testing
- Arm 1: Beveled Attachments, Conventional Rectangular Attachments
- Where
- Brazil
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Neodent
Malocclusions, Narrow Maxilla
Hyrax Vs. Invisalign Palatal Expander Clinical Study
The purpose of this study is to compare expansion result and the overall experience between the Invisalign Palatal Expander and the Hyrax expander.
- Conditions
- Malocclusions, Narrow Maxilla, Narrow Maxillary Arch, Crowding
- Trial name
- NCT06662279
- Testing
- Removable Rapid Palatal Expander, Banded Palatal Expander
- Where
- 4 sites in United States
- Volunteers
- 36 people
- Sponsor
- Align Technology, Inc.
Malocclusion
Evaluation of Clear Aligner Trays to Straighten Teeth
The objective of this study is to evaluate the efficacy of Clear Aligners to correct tooth malocclusions with the use of attachments and/or buttons, as determined by the amount of teeth movement and overall achievement goals of…
- Trial name
- NCT03141788
- Testing
- Clear Aligner
- Where
- 9 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Solventum Orthodontics Corporation
Dental Malocclusion
Precision Orthodontics: A Comparison of Custom vs Traditional Bracket Treatment Efficiency
This investigational testing aims to target multiple investigations sites to examine treatment efficiency metrics using a completely digital and patient-specific bracket treatment system for the correction of malocclusions.
- Trial name
- NCT04266769
- Testing
- LightForce Orthodontic System
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- LightForce Orthodontics
Class II Malocclusion, Mandibular Advancement
Invisalign® System with Mandibular Advancement
The goal of this clinical trial is to observe study participants' comfort and fit of their aligners with occlusal blocks, as well as evaluate the engagement of the blocks using the Invisalign® System with mandibular advancement…
- Conditions
- Class II Malocclusion, Mandibular Advancement, Mandibular Retrognathism, Excessive Overjet
- Trial name
- NCT06651944
- Testing
- Invisalign® System with mandibular advancement featuring occlusal blocks
- Where
- 3 sites in Canada
- Volunteers
- 36 people
- Sponsor
- Align Technology, Inc.
Malocclusion
Class II Correction Study Using the Invisalign System
To demonstrate that growing teenagers which present up to full cusp Class II malocclusions can be treated using the Invisalign System.
- Trial name
- NCT02376829
- Testing
- Invisalign System
- Where
- 10 sites in United States, Canada
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Dental Malocclusion, Edentulous Mouth
Safety and Technical Performance of Plastalgin and Plastalgin Fast in Patients Requiring a Dental Impression
The aim of this study is to gather clinical data related to the use of Plastalgin and Plastalgin Fast, in order to comply with the new medical device regulation.
- Conditions
- Dental Malocclusion, Edentulous Mouth, Dental Misalignment
- Trial name
- NCT05614635
- Testing
- Plastalgin and Plastalgin Fast
- Where
- 2 sites in France
- Volunteers
- 59 people
- Sponsor
- Septodont
Malocclusion
EXD-959 Orthodontic Brackets and EXD-961 Related Instruments Trial
The purpose of this study is to assess the performance of the EXD-959 self-ligating ceramic bracket system using EXD 961 instruments in the treatment of orthodontic malocclusion.
- Trial name
- NCT03606551
- Testing
- EXD-959 Bracket System
- Where
- 5 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- 3M
Malocclusion
Primer Aligner Study
To demonstrate that a primer aligner product can achieve similar results to the currently marketed product.
- Trial name
- NCT02550938
- Testing
- Invisalign
- Where
- 19 sites in United States, United Kingdom
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Malocclusion
One Week Aligner Evaluation
The purpose of this study is to demonstrate that changing aligners weekly provides similar results to changing aligners every two weeks.
- Trial name
- NCT02603289
- Testing
- Invisalign
- Where
- 24 sites in United States, Canada
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Abnormalities, Jaw, Malocclusion, Angle Class III
First-In-Man Performance and Safety Evaluation of the CARLO® Device in Midface Osteotomies
The study product is a Cold Ablation Robot-guided Laser Osteotome (CARLO®) robotic surgery device. It is a device that removes hard tissue such as bone by means laser ablation - it is therefore an alternative to Piezo-Electric…
- Trial name
- NCT03901209
- Testing
- Mid-face osteotomy
- Where
- 4 sites in Austria, Germany and 1 more
- Volunteers
- 31 people
- Sponsor
- Advanced Osteotomy Tools (AOT) AG
Malocclusion
The Use of Clear Aligners With Movement Enhancement Techniques
The purpose of this study is to use clear aligners to measure tooth movement and length of treatment.
- Trial name
- NCT02087163
- Testing
- Movement Enhancement Technique, Clear Aligner
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Malocclusion
OrthoPulse 2.0 and 2.1 Feasibility Evaluation
OrthoPulse is a device that uses near-infrared light therapy in order to decrease orthodontic treatment time. The aim of this study is to evaluate OrthoPulse products modified with extended arrays, OrthoPulse 2.0 and OrthoPulse…
- Trial name
- BX13 (NCT03683017)
- Testing
- OrthoPulse 2.0, OrthoPulse 2.1, Invisalign 3.5 Day Wear
- Where
- 7 sites in United States, Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion
The Effect of OrthoPulse™ on the Rate of Orthodontic Tooth Movement
This open label study is designed to evaluate the ability of OrthoPulse™ to safely and effectively increase the rate of orthodontic tooth movement with fixed appliances.
- Trial name
- BX8RN (NCT02267811)
- Testing
- Orthodontic Treatment, OrthoPulse™
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion
The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances
The aim of this study is to determine efficacy of OrthoPulse photobiomodulation on the rate of tooth movement during alignment for Subjects receiving fixed appliance orthodontic treatment.
- Trial name
- NCT03202355
- Testing
- Fixed Appliance Orthodontic Treatment, OrthoPulse™
- Where
- 3 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion
The Effect of OrthoPulse™ Photobiomodulation on Tooth Movement and Treatment Time When Used With Invisalign Treatment
The aim of the study is to determine if, and to what degree photobiomodulation treatment with OrthoPulse has an effect on the rate of tooth movement during alignment for patients receiving Invisalign orthodontic aligner treatment.
- Trial name
- NCT02954133
- Testing
- Invisalign (7 day), Invisalign (5 day), OrthoPulse
- Where
- 4 sites in United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.