Clinical trials: Malocclusion, Class I/II
Malocclusion, Angle Class II, Malocclusion, Angle Class III
Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative Time
The purpose of this study is to find out if 3D printed patient-specific titanium plates improve surgical accuracy and decrease operative time compared to milled patient-specific titanium plates in patients having Le Fort I…
- Conditions
- Malocclusion, Angle Class II, Malocclusion, Angle Class III, Dentofacial Deformities, Osteotomy, Le Fort I
- Trial name
- TiPlateRCT (NCT07841067)
- Testing
- 3D-Printed Patient-Specific Titanium Plates, Milled Patient-Specific Titanium Plates
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Future University in Egypt
Malocclusions, Malocclusion, Angle Class I
Microanalysis of Changes in 3D Geometry of Orthodontic Mini-implants
The orthodontic mini-implants used in the study are temporary screws inserted into the bone to provide anchorage for challenging tooth movements that could not be carried out using the patient's own teeth.
- Conditions
- Malocclusions, Malocclusion, Angle Class I, Malocclusion, Angle Class II
- Trial name
- NCT06743360
- Testing
- Insertion, Scanning
- Where
- 2 sites in Poland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Class II Division 1 Malocclusion
The Effect of Autologous Platelet Concentrations on Orthodontic Treatment Time
60 patients needed therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines were divided to randomly three groups: (1) PRP group: Received PRP injections, (2) I-PRF group…
- Trial name
- NCT05335824
- Testing
- The platelet-rich plasma (PRP), The injectable platelet-rich fibrin (I-PRF) group, The control group
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Class II Div 1 Malocclusion
Root Resorption in Class II Div 1 Malocclusion in Upper 1st Premolar Extraction vs Distalization
Rationale: Class II Division 1 malocclusion is characterized by upper anterior teeth protrusion resulting in upper lip protrusion and convex facial profile, which are considered esthetically unfavorable.
- Trial name
- NCT05639725
- Testing
- maxillary Ist premolar extraction, SURGICAL
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Class II Malocclusion
Evaluation of Skeletal and Dental Effect of the New Hybrid Aesthetic Functional Appliance
use new hybrid aesthetic functional appliance for treatment of class II div 1 malocclusion.
- Trial name
- NCT06209125
- Testing
- hybrid aesthetic functional appliance
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Malocclusion, Class I/II
Comparison of Corticotomy and Micro-Osteoperforation During Canine Retraction
Corticotomy and micro-osteoperforation (MOP) have been proven to accelerate tooth movement and shorten orthodontic treatment time, compared to conventional treatment.
- Trial name
- NCT04999150
- Testing
- Micro-Osteoperforations, Corticotomy
- Where
- Puerto Rico
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Malocclusion, Angle Class I, Malocclusion; Angle Class II Division 1
Efficiency of Piezo-Corticision in Accelerating Orthodontic Tooth Movement
The purpose of this study is to provide evidence on the effectiveness, the efficiency and efficacy of Peizo-Corticission in accelerating orthodontic tooth movement and reducing orthodontic treatment time.
- Trial name
- NCT02549950
- Testing
- Peizocorticision, Conventional Orthodontic Mechanics
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- AL Yousef
Malocclusion, Class I/II, Crowding, Tooth
Treatment Outcome of Clear Aligner and Traditional Fixed Appliances in Four Premolar Extraction Cases
Patients with severe crowding requiring the extraction of four premolars will be enrolled in this study. The degree of apical root resorption associated with using the clear aligner technique compared with vestibular fixed…
- Trial name
- NCT07236775
- Testing
- Clear Aligners, Traditional fixed appliances
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Malocclusion, Class I/II, Crowding
A Comparative Study Between Modified Miniscrew-Assisted Rapid Palatal Expander And Modified Rapid Palatal Expander in Molar Distalization Using Cone- Beam Computed Tomography
Comparative study between modified miniscrew-assisted rapid palatal expander and modified rapid palatal expander in molar distalization using CBCT.
- Conditions
- Malocclusion, Class I/II, Crowding, Maxillary First Molar Distalization
- Trial name
- MIDPAC (NCT07038902)
- Testing
- Group A: Modified Miniscrew-Assisted Rapid Palatal Expander (MARPE), Group B: Modified Rapid Palatal Expander (RPE)
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion, Angle Class I, Malocclusion, Angle Class II
3D Printed Occlusal Splints for Intraoperative Use
A 3D printed intraoperative occlusal splint is a custom-made biocompatible resin guide that allows surgeons properly align a patient's upper and lower dentition during surgery.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- NCT07079111
- Testing
- Formlabs 3D printed occlusal splint, Industry made occlusal splint
- Volunteers
- 70 people
- Sponsor
- Johns Hopkins University
Tooth Crowding, Malocclusion
Predictability of Orthodontic Tooth Movement With Invisalign Aligners
Together with the increased adult patient demand for orthodontic treatment and the push toward increasingly personalized treatment, technology developments have resulted in a growing worldwide demand for clear aligners, to the…
- Conditions
- Tooth Crowding, Malocclusion, Malocclusion, Angle Class II, Malocclusion, Class I/II
- Trial name
- NCT05356780
- Testing
- Aligner
- Where
- Italy
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Malocclusion, Angle Class I, Malocclusion, Angle Class II
AI-Assisted Versus Conventional Orthodontic Diagnosis and Treatment Planning
This study compared an artificial intelligence-assisted orthodontic diagnostic workflow using WebCeph with a conventional clinician-based workflow.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- AI-OrthoDx (NCT07690774)
- Where
- Yemen
- Volunteers
- 120 people
- Sponsor
- Ben Hafeed Dental Center
Dental Malocclusion, Angle Class II
BRIUS Vs FFA Efficiency
The purpose of this study is to compare the Full Fixed Preadjusted appliances (regular braces) when to the BRIUS system.
- Conditions
- Dental Malocclusion, Angle Class II, Angle Class I, Crowding, Tooth
- Trial name
- NCT04347018
- Testing
- BRIUS
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Class I Malocclusion, Class II Div 1 Malocclusion
Assesment of Ethnic Bias in an Artificial Intelligence Based Orthodontic Diagnosis System
This study explores how artificial intelligence (AI) can be used in orthodontics, which is the area of dentistry that focuses on correcting jaw and bite problems.
- Conditions
- Class I Malocclusion, Class II Div 1 Malocclusion, Class II Division 2 Malocclusion, Class III Malocclusion
- Trial name
- NCT07162753
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
CLASS II DIVISION 1 MALOCCLUSION
Response of Individuals With Class II Malocclusion
This investigation aims at distinguishing the subjects that react in a favorable way to the treatment protocol we propose for the Class II treatment
- Trial name
- NCT00248014
- Testing
- Mandibular Advancement Via A Functional Appliance
- Where
- Greece
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Malocclusion Class II, Malocclusion, Angle Class I
Effect of Early Versus Late Premolar Extraction on Orthodontic Tooth Movement
The goal of this randomized controlled trial is to evaluate whether the timing of premolar extraction affects the rate of orthodontic space closure during en-masse anterior retraction.
- Trial name
- NCT07773389
- Testing
- Early Maxillary First Premolar Extraction, Late Maxillary First Premolar Extraction
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Shifa College of Dentistry
Malocclusion
Evaluation of Clear Aligner Trays to Straighten Teeth
The objective of this study is to evaluate the efficacy of Clear Aligners to correct tooth malocclusions with the use of attachments and/or buttons, as determined by the amount of teeth movement and overall achievement goals of…
- Trial name
- NCT03141788
- Testing
- Clear Aligner
- Where
- 9 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Solventum Orthodontics Corporation
Malocclusion, Angle Class II, Division 1
Efficacy of Injectable Platelet Rich Fibrin (i-PRF) in Enhancing Bone Quality
Twenty patients need therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines, will be divided randomly into two groups, and will randomly assigned to one side of the maxillary…
- Trial name
- NCT03399760
- Testing
- i-PRF, canine retraction
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Malocclusion, Angle Class II, Division 1, Bimaxillary Protrusion
LLLLT vs Piezocision in Accelerating Orthodontic Canine Retraction
This comparative controlled clinical study aims to evaluate and compare the effectiveness of piezocision and low-level laser therapy (LLLT) as adjunctive interventions to accelerate orthodontic canine retraction.
- Conditions
- Malocclusion, Angle Class II, Division 1, Bimaxillary Protrusion, Class I Malocclusion
- Trial name
- NCT07466641
- Testing
- Low Level Laser Therapy, Piezocision
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Hesham Nabil Ali Al-Qamhawy
Malocclusion, Angle Class II, Division 1
Efficacy of Biological Technique in Upper Canine Retraction and Levels of Discomfort
Twenty patients need therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines, will be divided randomly into two groups, and will randomly assigned to one side of the maxillary…
- Trial name
- NCT03399422
- Testing
- i-PRF, canine retraction
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University