Clinical trials: Malnutrition, Child
Maternal Obesity Complicating Pregnancy, Birth,or Puerperium, Child Malnutrition
Addressing the Double Burden of Malnutrition in Guatemala
Globally, populations are experiencing increases in the double burden of malnutrition, commonly defined as maternal overweight/obesity and child stunting in the same household.
- Trial name
- NCT06750120
- Testing
- Family food ration, Optimal weight counseling, Enhanced Usual Care
- Where
- Guatemala
- Volunteers
- 1,532 people
- Sponsor
- Brigham and Women's Hospital
Zinc Deficiency, Mother and Child Malnutrition
Multi-Omic Profiling of a Zinc-Biofortified Maize Intervention in Guatemalan Mothers and Children
A trial evaluating the systemic and ecological impact of zinc-biofortified maize consumption on cellular zinc status, inflammatory biomarkers, and gut microbiota composition in a cohort of Guatemalan mothers and children.
- Trial name
- NCT07585318
- Testing
- F3 Biofortified Maize, Conventional Maize
- Where
- Guatemala
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition of Central America and Panama
Prevention, Malnutrition, Child
Evaluation of 7-day vs 1-day Packaging of Small Quantity Lipid-based Nutrition Supplementation (SQ-LNS)
Small Quantity Lipid-based Nutrient Supplements (SQ-LNS), are fortified, lipid-based nutritional supplements that were specifically designed for children 6-24 months to prevent malnutrition.
- Conditions
- Prevention, Malnutrition, Child, Nutrition
- Trial name
- NCT07540793
- Testing
- 7dp SQ-LNS, 1dp SQ-LNS
- Where
- 3 sites in Ethiopia, Germany and 1 more
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Malnutrition in Children, Undernutrition
Nutrition Intervention Among Ethnic Minority Children Aged 5-16 Years in Tra Vinh Province, Vietnam
The goal of this study is to evaluate the effectiveness of a nutrition health education intervention among ethnic minority children aged 5-16 years in Tra Vinh Province, Vietnam.
- Conditions
- Malnutrition in Children, Undernutrition, Overweight, Obesity
- Trial name
- NCT07583667
- Testing
- Nutrition Health Education
- Where
- Vietnam
- Volunteers
- 811 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Malnutrition, Severe Acute, Malnutrition, Child
Slow Introduction of Nutrition for Ill Malnourished Children
The goal of this clinical trial is to learn if giving lower calorie feeds during the first stage of treatment helps improve survival in severely malnourished children who are ill.
- Conditions
- Malnutrition, Severe Acute, Malnutrition, Child, Malnutrition, Infant
- Trial name
- F50 (NCT06846749)
- Testing
- F75 milk feeds, F50 milk feeds, F35 milk feeds
- Where
- 2 sites in Bangladesh, Malawi
- Volunteers
- 135 people
- Sponsor
- The Hospital for Sick Children
Severe Acute Malnutrition in Childhood, Malnutrition, Child
Treatment of Severe Acute Malnutrition in Children 6 to 59 Months Old With Standard Ready To Use Therapeutic Food Compared to a Newly Formulated Lipid Optimized Ready To Use Therapeutic Food
The goal of this randomized clinical trial is to learn if a newly formulated Lipid-Optimized Ready-to-Use Therapeutic Food (LO-RUTF) can treat severe acute malnutrition in children aged 6 to 59 months.
- Conditions
- Severe Acute Malnutrition in Childhood, Malnutrition, Child, Neurocognition, Child
- Trial name
- NCT07345884
- Testing
- Lipid-Optimized Ready to Use Therapeutic Food (RUTF), Ready to Use Therapeutic Food (RUTF)
- Where
- Pakistan
- Volunteers
- 125 people
- Sponsor
- University of California, Los Angeles
Malnutrition, Child
Childrens Real Food Tolerance Study
A prospective, longitudinal, 28-day intervention study evaluating the tolerance, compliance, acceptability and safety to two new enteral tube feed and one new oral nutritional supplement based on real food ingredients (1kcal/ml…
- Trial name
- NCT05269992
- Testing
- Real food products
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Nutricia UK Ltd
Tuberculosis, Child Health
The DECIDE-TB Trial; Validation of Treatment Decision Algorithms for Childhood Tuberculosis
The Decide-TB project aims to generate evidence for the implementation of a comprehensive Treatment Decision Algorithms (TDA) based approach for TB in children living in high TB burden and resource-limited countries, at District…
- Conditions
- Tuberculosis, Child Health, HIV, Severe Acute Malnutrition
- Trial name
- DTB (NCT06593080)
- Testing
- The comprehensive TDA based approach
- Where
- 29 sites in Zambia
- Volunteers
- 30,240 people, healthy volunteers welcome
- Sponsor
- Chishala Chabala
Malnutrition, Child, Malnourishment
the Effect of High Caloric Oral Nutritional Supplements on Growth and Development of Malnourished Children
The goal of this clinical trial is to investigate the effect of high caloric oral nutritional supplements on body proportion, weight, linear growth pattern, neuropsychological development level and related health aspects (gut…
- Conditions
- Malnutrition, Child, Malnourishment, Nutritional Deficiency, Undernutrition
- Trial name
- EHCONSGDMC (NCT05911893)
- Testing
- high caloric oral nutritional supplements, nutritional education, dietary guidance
- Where
- 13 sites in China
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Pediatric Cancer, Malnutrition, Child
From Kitchen to Clinic
Children receiving cancer treatment often experience nutrition-related challenges, such as changes in appetite, weight, and food intake, due to treatment side effects and the demands placed on families during care.
- Conditions
- Pediatric Cancer, Malnutrition, Child, Caregiver Burden
- Trial name
- NCT07454902
- Testing
- Medically Tailored Meals, Caregiver Coaching
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Drexel University
Malnutrition in Pregnancy, Preterm Birth
Improving Cognition and Gestational Duration With Targeted Nutrition
The goal of this clinical trial is to test (1) a novel maternal ready-to-use supplementary food and (2) a novel cognitive behavioral therapy intervention in undernourished Sierra Leonean women.
- Conditions
- Malnutrition in Pregnancy, Preterm Birth, Child Development, Postpartum Depression
- Trial name
- COGENT (NCT05949190)
- Testing
- M-RUSF+ (Maternal Ready-to-Use Supplementary Food + DHA/EPA/choline), M-RUSF (Maternal Ready-to-Use Supplementary Food), Azithromycin
- Where
- 10 sites in Sierra Leone
- Volunteers
- 1,660 people
- Sponsor
- Washington University School of Medicine
Malnutrition, Infant, Malnutrition, Child
Efficacy of Mobile Health Application in Promotion of Exclusive Breast Feeding and Young Child Feeding Practices in Pakistan
Early life nutrition is the key modifiable determinant of child growth, development, survival and diseases of adult onset. Pakistan ranks highest for neonatal mortality rate (44.2/1000 live births (LBs)) globally.
- Trial name
- NCT05590351
- Testing
- First diet: m-health coaching application, Face to Face counselling
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Undernutrition, Healthy Nutrition
Women Supporting Women to Improve Infant and Child Feeding Practices
Undernutrition in the first 2 years of life is the largest preventable cause of death before age 5. Among those who survive, stunting before age two leaves millions with lifelong physical and cognitive deficits, which are…
- Conditions
- Undernutrition, Healthy Nutrition, Health Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT05473312
- Testing
- Community Sensitization, 28-day PD/Hearth Sessions, Supplemental Print Information
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- Aga Khan University
Malnutrition in Children
Women Supporting Women to Improve Infant and Child Feeding Practices in Pakistan
This project aims to reduce child malnutrition in Pakistan by building on local strengths and practical community solutions. The project focuses on children 7-23 months of age.
- Trial name
- NCT07345754
- Testing
- 28-day Behavioural Change Program
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- University of British Columbia
Cerebral Palsy (CP), Malnutrition in Children
Assessment of Nutritional Status Using Mid-Upper Arm Circumference Z-Score in Children With Cerebral Palsy
Children with cerebral palsy are at increased risk of malnutrition due to motor impairment, feeding difficulties, and chronic health problems.
- Trial name
- NCT07351695
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Muğla Sıtkı Koçman University
Nutrition, Growth
Impact of Diet and Nutrition on Growth and Development in Young Children
The association between nutrition in early life and its long-term health consequences has long been known. However, there is a scarcity of scientific evidence on how nutritional status affects child growth and development in…
- Conditions
- Nutrition, Growth, Development, Stunting
- Trial name
- DIGEST (NCT06018636)
- Where
- Pakistan
- Volunteers
- 832 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Iron Absorption, Iron Deficiencies
Maximizing the Benefits of Iron in Ready-to-Use Therapeutic Foods for Malnourished Children in Kenya
Reports from the Kenya Red Cross Society (KRCS) in Kwale County, southern Kenya, indicate a limited impact of Ready-to-Use Therapeutic Foods (RUTFs) on malnutrition or anemia.
- Conditions
- Iron Absorption, Iron Deficiencies, Severly Acutely Malnourished Children, Malnutrition in Children
- Trial name
- SAMI (NCT07315295)
- Testing
- Iron absorption from RUTF on Day 0, Treatment with RUTF for 80 days, Iron absorption from RUTF on Day 20
- Where
- 2 sites in Kenya, Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
HIV Infections, HIV/AIDS
Evaluation of a Home-based Community Health Worker Program in Rural Eastern Cape, South Africa
The purpose of this early Phase 2 comparison trial is to evaluate the impact of community health worker (CHW) home visitors on pregnant women and their children in a rural setting in the rural Eastern Cape of South Africa.
- Conditions
- HIV Infections, HIV/AIDS, Depression, Depressive Symptoms
- Trial name
- NCT03517878
- Testing
- Comprehensive CHW Program
- Where
- 2 sites in South Africa
- Volunteers
- 1,490 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Malnutrition, Child, Malnutrition, Infant
Mother Screening for Relapse Using Mid-upper Arm Circumference Among Children Recovered From Severe Acute Malnutrition (Full Scale Trial)
A 1:1:1 individually randomized unmasked controlled trial is proposed in which caregivers will be trained to screen their children who have recovered from an episode of SAM (severe acute malnutrition) using MUAC (mid-upper arm…
- Conditions
- Malnutrition, Child, Malnutrition, Infant, Malnutrition or Risk of Malnutrition, Hemoglobin Level Measurement
- Trial name
- MAMAN (NCT06599580)
- Testing
- Training caregivers to screen children for malnutrition relapse, Reduced follow-up schedule
- Where
- Burkina Faso
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Malnutrition, Child, Severe Acute Malnutrition
Azithromycin as Adjunctive Treatment for Uncomplicated Severe Acute Malnutrition
Amoxicillin is recommended by the World Health Organization (WHO) as adjunctive therapy for the treatment of uncomplicated severe acute malnutrition (SAM).
- Trial name
- AMOUR (NCT06010719)
- Testing
- Azithromycin, Amoxicillin
- Where
- Burkina Faso
- Volunteers
- 3,000 people
- Sponsor
- University of California, San Francisco