Clinical trials: Malignant Hypertension
Glaucoma, Malignant Glaucoma
Study on Intraocular Structural Parameters and Surgical Effect Before and After the Onset of Malignant Glaucoma
In this retrospective observational study, we collected intraocular structure parameters of malignant glaucoma and primary angle closure glaucoma.
- Trial name
- MG (NCT04220879)
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Biliary Tract Neoplasms, Pancreatic Neoplasm
Portal Vein Stenting for Malignant Obstruction: Feasibility, Safety, and Clinical Outcomes
Introduction: Pre-hepatic portal hypertension of malignant origin can lead to severe complications such as refractory ascites or gastrointestinal bleeding, significantly impairing patients' quality of life.
- Conditions
- Biliary Tract Neoplasms, Pancreatic Neoplasm, Portal Hypertension, Portal Vein Thrombosis
- Trial name
- NCT07252570
- Testing
- Transhepatic portal vein stent implantation
- Where
- France
- Volunteers
- 63 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc)
Pragmatic RCT of AI-Assisted Reading for Malignant Hepatic Lesions on CE-CT
The purpose of this multicenter pragmatic randomized controlled trial is to determine whether AI-assisted interpretation of multiphasic liver contrast-enhanced computed tomography (CE-CT) is non-inferior to standard radiology…
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma
- Trial name
- NCT07768085
- Testing
- AI-assisted abdominal CE-CT reporting, Standard abdominal CE-CT reporting without AI assistance
- Where
- China
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Oncological Comorbidities (e. g. Hypertension, Diabetes, Malnutrition)
AI-Assisted Comprehensive Management for Cancer Patients With Comorbidities (GCOG-CG001)
Combined with the digital whole process management data pool, a multi-modal data fusion framework is developed, and an AI model is established to realize risk stratification and personalized treatment Recommendation and dynamic…
- Trial name
- GCOG-CG001 (NCT07136727)
- Testing
- AI-assisted comprehensive management system
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Malignant Hypertension
A New Breath for Malignant Hypertension: Implementation of the HAMA Cohort
This registry aims to provide the first prospective, multicentric database of patients with malignant hypertension. It will allow to assess modern epidemiology of the disease, diversity of current management and care pathway, to…
- Trial name
- HAMA (NCT03755726)
- Where
- 37 sites in France, Poland
- Volunteers
- 1,200 people
- Sponsor
- Centre Hospitalier de PAU
Pulmonary Hypertension
Pulmonary Hypertension and Arrhythmia
Patients with pulmonary hypertension underwent (routine) Holter ECG and were screened for (malignant) arrhyhtmias. Results of Holter ECGs were correlated with clinicial and technical data (echocardiography and right heart…
- Trial name
- NCT05496504
- Testing
- Holter ECG
- Volunteers
- 222 people
- Sponsor
- Asklepios Neurological Clinic Bad Salzhausen
Malignant Hypertension
Determinants of Malignant Hypertension Onset and Related Target Organ Damages: the HAMA Biobank
The HAMA bank is an initiative aimed at collecting, preparing, and storing biological samples from patients treated for malignant hypertension and included in the HAMA cohort.
- Trial name
- HAMABANK (NCT06629363)
- Testing
- biobank
- Where
- 11 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier de PAU
Malignant Media Infarction, Stroke
Optic Nerve Sonography to Monitor Intracranial Pressure After Ischemic sTrokE - The ONSITE Study
The goal of the ONSITE study is to investigate whether an increase Optic nerve sheath diameter (ONSD) may help to predict intracranial hypertension (IH) after stroke.
- Conditions
- Malignant Media Infarction, Stroke, Intracranial Hypertension
- Trial name
- ONSITE (NCT06939114)
- Where
- Switzerland
- Volunteers
- 107 people
- Sponsor
- University of Zurich
Hypertension, Malignant, Airway Management
Using Ambu Aura-i Laryngeal Mask Airway in Cranial Surgery
the investigators hypothesize that Ambu aura-i LMA can be used safely in patients undergoing craniotomies and are effective in reducing the incidence of emergence hypertension.
- Trial name
- NCT04582227
- Testing
- Ambu aura-i LMA
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Intracranial Pressure Increase
Non-invasive Absolute Intracranial Pressure Measurement in Patients With Malignant Middle Cerebral Artery Infarction for Determination of Timing to Descompressive Craniectomy.
This is a single centre, observational study with a medical device which has Conformité Européenne (CE) marking. The aim of the study is to demonstrate that patients with malignant middle cerebral artery infarction (M-MCA) show…
- Trial name
- NCT03221959
- Testing
- Medical Device Vittamed 205
- Volunteers
- 48 people
- Sponsor
- Kienzler Jenny
Malignant Hypertension
Interrupters of VAscular daMAge in Malignant Hypertension
The pathophysiology of malignant hypertension is poorly understood. The objective of this translational research project is to evaluate the relationship between activation of vasoactive systems (renin-angiotensin and endothelin…
- Trial name
- IVAMA (NCT04991077)
- Testing
- analyse of angiogenic, vasoactive and VEGF systems
- Where
- 7 sites in France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier de PAU
Metastatic Malignant Melanoma, Unresectable Malignant Melanoma
Bevacizumab vs Dacarbazine in Metastatic Melanoma
The purpose of this study is to compare efficacy of bevacizumab monotherapy with standard chemotherapy (DTIC) in patients with metastatic malignant melanoma.
- Trial name
- NCT01705392
- Testing
- Bevacizumab, Propranolol, Enalapril
- Where
- Norway
- Volunteers
- 2 people
- Sponsor
- Haukeland University Hospital
Chronic Non-communicable Disease
Risk Factors at Chronic Non-communicable Diseases in People of Working Age
Objectives: to study the clinical and demographic characteristics of working age persons, to highlight the main factors of non-communicable diseases (NCDs), to identify NCDs with physical examination, laboratory tests…
- Trial name
- FORTUNE (NCT06812767)
- Testing
- electrocardiography, analysis for glucose and cholesterol in the capillary blood, detection of microalbumuria
- Where
- Russia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Middle Cerebral Artery Infarction
Stereotactic Infarct Tissue Aspiration for Malignant Infarction of Middle Cerebral Artery
Malignant middle cerebral artery infarction(MMCI) has a high rate of disability and mortality. At present, there is no effective treatment except for craniotomy decompression, but the controversy of the craniotomy decompression…
- Trial name
- SMART (NCT02609256)
- Testing
- Stereotactic infarct tissue aspiration, Medical therapy
- Where
- China
- Volunteers
- 12 people
- Sponsor
- General Hospital of Shenyang Military Region
Appendicitis, Cholelithiasis
Single Incision Laparoscopy
Laparoscopic surgery being performed with only one small incision via the umbilicus (belly button).
- Conditions
- Appendicitis, Cholelithiasis, Malignant Hypertension
- Trial name
- SIL (NCT00616616)
- Testing
- single incision laparoscopic surgery
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, San Diego