Clinical trials: Magnetoencephalography (MEG)
Healthy
Acute Effect of Three Neuroactive Drugs Measured by Magnetoencephalography (MEG), Electroencephalography (EEG) and the Synchronous Neural Interaction Test
This placebo-controlled crossover study is intended to measure the effect of three, common neuroactive medications on brain activity measured by magnetoencephalography (MEG) and electroencephalography (EEG).
- Trial name
- NCT00972985
- Testing
- modafinil, methylphenidate, lorazepam
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Orasi Medical, Inc.
Epilepsy
Combined Role of Position Emission Tomography (PET) and Magnetoencephalography (MEG) in Nonlesional Epilepsy
The first aim of this study are to evaluate the lobar concordance of FDG-PET and MEG with intracranial electrographic study in children with intractable partial epilepsy.
- Trial name
- NCT00741559
- Testing
- magnetoencephalography, Positron emission tomography (PET), Magnetic resonance imaging
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- The Hospital for Sick Children
Fibromyalgia
Brain Rhythms in Fibromyalgia: A Magnetoencephalography (MEG) Study
The long-term purpose of the investigator's research is to understand the pathophysiological basis of chronic pain. This will help provide a framework for the development of effective treatments.
- Trial name
- FMP (NCT02159300)
- Testing
- experience brain activity recording
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Major Depressive Disorder, Treatment-Resistant Depression
Antidepressant Effects of TS-161 in Treatment-Resistant Depression
Background: Major depressive disorder (MDD) is a common, chronic mental illness. It can take weeks to months for antidepressants to work. Researchers want to test a new drug that might act more rapidly.
- Conditions
- Major Depressive Disorder, Treatment-Resistant Depression, Depression
- Trial name
- NCT04821271
- Testing
- TS-161
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- National Institute of Mental Health (NIMH)
Primary Progressive Aphasia
HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms
This study aims to evaluate the effectiveness of a therapy called High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for the treatment of the language deficits experienced by people with a type of Primary…
- Trial name
- NCT03805659
- Testing
- HD-tDCS
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Medical College of Wisconsin
Severe Permanent Uni or Bilateral Non-pulsatile Tinnitus, Without Associated Vestibular Pathology
Evaluation of Deep Brain Stimulation (DBS) of the Right Operculum 3 (OP3) in Permanent Non-pulsatile Disabling Tinnitus (TINNOP3-DBS)
This pilot study aims at evaluating the effectiveness of the treatment of unilateral or bilateral, non-pulsatile, disabling, tinnitus, without vestibular dysfunction, using Deep Brain Stimulation (DBS) of the parieto-insular…
- Conditions
- Severe Permanent Uni or Bilateral Non-pulsatile Tinnitus, Without Associated Vestibular Pathology, Resistant to Therapeutic Failure, With or Without Hearing Loss
- Trial name
- TINNOP3-DBS (NCT04296097)
- Testing
- DBS
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Grenoble
Healthy Volunteers
Study of Somatosensory Responses During Millimeter Waves Application
The brain activity induced by a sensory stimulus and measured by magnetoencephalography will be compared before and after exposure to millimeter waves.
- Trial name
- RESOM (NCT04801550)
- Testing
- Millimeter waves local exposure
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Tinnitus
MaST: MEG and Brain Stimulation in Tinnitus
Tinnitus is the awareness of a sound in the ear or head without any outside source. It affects around 15% of people in the UK. About 20% of people with tinnitus experience symptoms that negatively affect their quality of life…
- Trial name
- MaST (NCT04978142)
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Nottingham
Epilepsy
Non-Invasive Seizure Localization in Patients With Medically Refractory Localization Related Epilepsy: Synchronized MEG-EEG Recordings
This study will evaluate the magnetoencephalography (MEG) alone and together with electroencephalography (EEG) in non-invasive presurgical evaluation.
- Trial name
- NCT00071305
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Sleep Disorders
Providing "Good Sleep" for ICU Sedation
Cognitive dysfunction, either alone or as an element in the syndrome of delirium, is a common occurrence with an incidence as high as 75% in intensive care unit (ICU) patients and can independently result in serious consequences…
- Trial name
- ASRV (NCT01342328)
- Testing
- Normal saline infusion, Dexmedetomidine, Propofol
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cerebral Primitive Tumor With Chirurgical Indication
Glial Tumors Electromagnetic Signature Study by MagnetoEncephaloGraphy (MEG) "CONDUCTOME"
The purpose of this study is to determine the correlation between functional MEG analysis of the tumor and its periphery and the tumor stage and treatment response.
- Trial name
- CONDUCTOME (NCT02077504)
- Testing
- MEG and MRI
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Schizophrenia, Oxytocin
Oxytocin MEG Study
The specific aim of this proposal is to investigate the neurophysiological mechanisms of oxytocin's (OT) prosocial effects in patients with schizophrenia and healthy subjects using magnetoencephalography.
- Conditions
- Schizophrenia, Oxytocin, Magnetoencephalography (MEG), Social Cognition
- Trial name
- MEG (NCT02568709)
- Testing
- Oxytocin, Saline Nasal Spray
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sleep Disorder Insomnia Chronic
A Study of the Mechanisms by Which Mood and Sleep Disorders Interact
The main purpose of the study is to explore the mechanisms by which mood and sleep disorders interact. The exploratory aim of this study is to discover the relationship between ECG/MCG and EEG/MEG characteristics and mood and…
- Trial name
- mechanisms (NCT07495189)
- Testing
- electrocardiographic/magnetic and electroencephalographic/magnetic monitoring data, ambulatory electrocardiogram, General clinical information
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Muscle Pain
Brain Network Characteristics of Pain Patients Based on Magnetoencephalography
This is a single-center prospective cohort study. We plan to enroll at least 1,000 patients with muscle pain (VAS ≥ 3) and 200 healthy controls.
- Trial name
- NCT07809542
- Testing
- Magnetoencephalography
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Cognition
Study to Test the Usefulness of Magnetoencephalography (MEG) Imaging of Cognition in Children and Adolescents
The primary objective of this protocol is to test the feasibility and utility of obtaining magnetoencephalography (MEG) recordings in healthy children and also in children who have a psychiatric or developmental disorder.
- Trial name
- NCT00924300
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Refractory Epilepsy in Children
Non-Helium Magnetoencephalography in Pediatric Refractory Epilepsy
The goal of this observational study is to evaluate the effectiveness of Magnetoencephalography (MEG) in the preoperative assessment of children with refractory epilepsy, particularly in identifying the seizure focus, and to…
- Trial name
- NCT07064421
- Testing
- Magnetoencephalography plus Stereo-electroencephalography/Electrocorticography, Stereo-electroencephalography/Electrocorticography
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Healthy Volunteers
Adjustment Exploratory Protocols and Functional Evaluation of New Non Invasive Devices in Healthy Volunteers
Parameters, sequences or paradigms optimisation in view of data quality and relevancy improvement.
- Trial name
- MAP-EFNI (NCT02790411)
- Testing
- Imaging devices, New Non Invasive Devices
- Where
- France
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Epilepsy
Activating Effects of Sleep Deprivation on Synchronized MEG-EEG Recordings of Epilepsy Patients With Non-Diagnostic EEG
This study will evaluate how the state of being completely deprived of sleep has an effect on recordings of magnetoencephalography (MEG) and electroencephalography (EEG), in relation to how alert someone is and how sleepy someone…
- Trial name
- NCT00071370
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Alcohol Use Disorder, Alcohol Dependence
Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study
Alcohol use disorder (AUD) is a complex chronic brain disease characterized by compulsive alcohol use, loss of control over drinking, and negative emotional states.
- Conditions
- Alcohol Use Disorder, Alcohol Dependence, Alcohol Consumption
- Trial name
- TMS (NCT06770556)
- Testing
- Active iTBS, 10 Hz TMS, 1 Hz TMS
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Traumatic Brain Injury, Post-concussive Symptoms
MEG and DTI of Neural Function and Connectivity in Traumatic Brain Injury
The overall hypothesis is that the long-term cognitive and behavioral sequelae of traumatic brain injury (TBI) are due to selective disruption of the long association white matter tracts of the cerebral hemispheres, with…
- Trial name
- Dana-REAC (NCT01298557)
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco